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The map label for this gene is map [H]

Identifier: 169630862

GI number: 169630862

Start: 3837414

End: 3838208

Strand: Reverse

Name: map [H]

Synonym: MAB_3782c

Alternate gene names: 169630862

Gene position: 3838208-3837414 (Counterclockwise)

Preceding gene: 169630863

Following gene: 169630855

Centisome position: 75.75

GC content: 66.92

Gene sequence:

>795_bases
GTGGGTCTCTTCGGCCGTAAGAAGACGGTGGAACAGCGCACGCCCGGTGAGCTCGACGCCATGGCTGCTGCCGGCTCCAT
CGTGGGGGCGGCGCTGGTCGCGGTGCGCGATGCCGCCAAGGCCGGGGTGTCGACGCTGGAGTTAGATCAGGTCGCCGAGT
CCGTGATCCGCGAGGCCGGAGCGGTGCCCTCGTTCCTGGGCTACCACGGCTTTCCGGCGTCCATCTGCTCATCGGTCAAC
GACCAGGTGGTGCACGGAATACCTTCCGCGACAGCGGTACTTGCCGACGGCGATCTTGTCTCCATCGATTGTGGCGCGAT
ACTGGACGGCTGGCACGGGGATTCCGCATGGACGTTCGCGGTAGGCACCGTCATCCCCAGTGACGAAGCGCTGTCCGAGG
CGACGCGTTTGTCGATGGAGGCGGGCATTGCGGCGATGATCCCGGGTAACCGGCTCACCGATGTCTCGCACGCCATCGAA
CTGGGCACCCGCGCCGCCGAGAAGCAATTCGACCGAGCGTTCGGAATCGTGGACGGCTACGGCGGGCACGGCATCGGGCG
CTCGATGCATCTGGATCCGTTCCTGCCGAACGAGGGAGCTCCCGGTAAGGGCCCGCTACTCGCGGTGGGATCGGTACTCG
CCATCGAACCGATGCTCACGCTCGGCACCACCCAGACTCGGGTGCTTGCCGACGATTGGACCGTTGTCACCACCGACGGG
TCTCGTGCCGCGCACTGGGAGCACACGGTGGCCGTCACCGAGGCCGGCCCCCGCATCCTCACCATGCGTCCCTAG

Upstream 100 bases:

>100_bases
ACTACCAGAACGTGCTGCAGACCATCGATGCCGTCGGCACGGTGGACGAGGTGTTCGCGCGCACCTCGCAGGCACTGGGC
CGGTAGTAGCGAGTTCGTTA

Downstream 100 bases:

>100_bases
CTATTTGCCCTTGATCGAGGCGGTGCGCTGCGTATCGAAGGTGGCCACGCACGCGATCGCCCGATCCCCTTGAGCCCATG
AACGTTTCGTCGGATACAGA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MGLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAGAVPSFLGYHGFPASICSSVN
DQVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFAVGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIE
LGTRAAEKQFDRAFGIVDGYGGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDG
SRAAHWEHTVAVTEAGPRILTMRP

Sequences:

>Translated_264_residues
MGLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAGAVPSFLGYHGFPASICSSVN
DQVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFAVGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIE
LGTRAAEKQFDRAFGIVDGYGGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDG
SRAAHWEHTVAVTEAGPRILTMRP
>Mature_263_residues
GLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAGAVPSFLGYHGFPASICSSVND
QVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFAVGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIEL
GTRAAEKQFDRAFGIVDGYGGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDGS
RAAHWEHTVAVTEAGPRILTMRP

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=256, Percent_Identity=33.203125, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI164420681, Length=224, Percent_Identity=36.1607142857143, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1786364, Length=252, Percent_Identity=37.6984126984127, Blast_Score=179, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=33.7209302325581, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6323273, Length=226, Percent_Identity=36.7256637168142, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=34.8178137651822, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24583427, Length=254, Percent_Identity=36.6141732283465, Blast_Score=151, Evalue=3e-37,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27275; Mature: 27144

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAG
CCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
AVPSFLGYHGFPASICSSVNDQVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFA
CCCHHHHCCCCHHHHHCCCCCHHHHCCCCCEEEEECCCEEEEECCCEEECCCCCCEEEEE
VGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGY
EEEECCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECC
GGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDG
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHCCHHHCCCCCEEEEECCEEEEEECC
SRAAHWEHTVAVTEAGPRILTMRP
CCCCCCEEEEEEECCCCEEEEECC
>Mature Secondary Structure 
GLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAG
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
AVPSFLGYHGFPASICSSVNDQVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFA
CCCHHHHCCCCHHHHHCCCCCHHHHCCCCCEEEEECCCEEEEECCCEEECCCCCCEEEEE
VGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGY
EEEECCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECC
GGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDG
CCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHCCHHHCCCCCEEEEECCEEEEEECC
SRAAHWEHTVAVTEAGPRILTMRP
CCCCCCEEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]