Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 169630762

GI number: 169630762

Start: 3736439

End: 3737461

Strand: Reverse

Name: trpS [H]

Synonym: MAB_3683c

Alternate gene names: 169630762

Gene position: 3737461-3736439 (Counterclockwise)

Preceding gene: 169630763

Following gene: 169630761

Centisome position: 73.76

GC content: 64.32

Gene sequence:

>1023_bases
ATGACTGCCGAAACCGCCGCCCGGGGACGCCTGTTCTCCGGTATTCAGCCCACCGCCGATTCTCTTCACCTCGGAAACGT
GCTGGGTGCGGTGCAGCAGTGGGTGCGGTTGCAGCACGAGTACGAGGCGCTGTTCTGTGTCGTCGACCTGCATGCGATCA
CGGTCGCCCAAGACCCCGAGGAACTTCGGCGGCGCACCCGCGCGGTGGTCGCACAGTACGTGGCACTCGGCGTCGACCCG
GCCAAGAGCGCCATCTTCGTGCAGAGCCACGTACCCGCACACGCCGAATTGGCTTGGGTACTGGGGTGTTTGACCGGTTA
CGGGGAAGCTGCCCGGATGACGCAGTTCAAGGACAAGTCGGCCAAGCAGGGTAACGACGCCACGACGGTAGGCCTGTTCA
CCTATCCGGTGCTGATGGCGGCCGACATCCTGCTGTACCAGACCAATGTGGTGCCGGTGGGTGACGACCAGCGTCAGCAC
CTCGAACTGACTCGGGATGTGGCGCAGCGATTCAACGGCCGGTACGGCCAGACATTCGTGCTGCCGGAGACGTTCGTGCC
GAAGAACGCGGCCCGTATCTACGACCTGCAGGACCCGACGGTCAAGATGAGCAAGTCGGCCTCCACTCCCGCCGGGCTGA
TCAACCTGCTCGATGAACCGGCGGTCTCGGCCAAAAAGGTCAAGTCGGCACAGACCGACAGCGACCGTGAGATCCGCTTT
GATCGGGACGCCAAGCCGGGTGTCTCCAATCTACTGAGCATCCAGTCCGCGCTCACCGGAGCCGATATCGAGACTCTCGT
GGACGGGTACGCCGGGCGCGGGTACGGGGACCTGAAGAAAGACACGGCCGAGGCGCTGATCGAATTCGTCACACCGGTCC
GTGACCGGACGAATGAGCTGCTCAGCGACACCGCGGCGCTCGACGACATCCTGGCTTCCGGTGCGGCGCGTGCCCGGGAG
CTGGCGGAGAAGACTCTCACCGAGGTCTATGACCGGATAGGGTTTGTCCGGCCCGCGAGGTAG

Upstream 100 bases:

>100_bases
TCCGATCACGCCCCGGTGACGGTGGAGTACCGGTAGGGCGCCTTGCGGCCAGAGCGGCAGCCAGAATCGCTTTGACCGGG
CATGCCAGGATGGATGCACT

Downstream 100 bases:

>100_bases
TTAACAGCAGAGGCGGTGAGTGGTGGCTGAAGACGACAAGCCTGGAATCCTTGACCGCTATCGCGCCAGATTTCCCTGGT
TCGACCACATCATGCGCATG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTAETAARGRLFSGIQPTADSLHLGNVLGAVQQWVRLQHEYEALFCVVDLHAITVAQDPEELRRRTRAVVAQYVALGVDP
AKSAIFVQSHVPAHAELAWVLGCLTGYGEAARMTQFKDKSAKQGNDATTVGLFTYPVLMAADILLYQTNVVPVGDDQRQH
LELTRDVAQRFNGRYGQTFVLPETFVPKNAARIYDLQDPTVKMSKSASTPAGLINLLDEPAVSAKKVKSAQTDSDREIRF
DRDAKPGVSNLLSIQSALTGADIETLVDGYAGRGYGDLKKDTAEALIEFVTPVRDRTNELLSDTAALDDILASGAARARE
LAEKTLTEVYDRIGFVRPAR

Sequences:

>Translated_340_residues
MTAETAARGRLFSGIQPTADSLHLGNVLGAVQQWVRLQHEYEALFCVVDLHAITVAQDPEELRRRTRAVVAQYVALGVDP
AKSAIFVQSHVPAHAELAWVLGCLTGYGEAARMTQFKDKSAKQGNDATTVGLFTYPVLMAADILLYQTNVVPVGDDQRQH
LELTRDVAQRFNGRYGQTFVLPETFVPKNAARIYDLQDPTVKMSKSASTPAGLINLLDEPAVSAKKVKSAQTDSDREIRF
DRDAKPGVSNLLSIQSALTGADIETLVDGYAGRGYGDLKKDTAEALIEFVTPVRDRTNELLSDTAALDDILASGAARARE
LAEKTLTEVYDRIGFVRPAR
>Mature_339_residues
TAETAARGRLFSGIQPTADSLHLGNVLGAVQQWVRLQHEYEALFCVVDLHAITVAQDPEELRRRTRAVVAQYVALGVDPA
KSAIFVQSHVPAHAELAWVLGCLTGYGEAARMTQFKDKSAKQGNDATTVGLFTYPVLMAADILLYQTNVVPVGDDQRQHL
ELTRDVAQRFNGRYGQTFVLPETFVPKNAARIYDLQDPTVKMSKSASTPAGLINLLDEPAVSAKKVKSAQTDSDREIRFD
RDAKPGVSNLLSIQSALTGADIETLVDGYAGRGYGDLKKDTAEALIEFVTPVRDRTNELLSDTAALDDILASGAARAREL
AEKTLTEVYDRIGFVRPAR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=42.2960725075529, Blast_Score=271, Evalue=5e-73,
Organism=Homo sapiens, GI41352700, Length=181, Percent_Identity=51.3812154696133, Blast_Score=193, Evalue=2e-49,
Organism=Escherichia coli, GI1789786, Length=328, Percent_Identity=51.5243902439024, Blast_Score=345, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=37.1601208459215, Blast_Score=221, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71982793, Length=331, Percent_Identity=37.1601208459215, Blast_Score=220, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=40.8695652173913, Blast_Score=226, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24666151, Length=328, Percent_Identity=41.4634146341463, Blast_Score=260, Evalue=9e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37101; Mature: 36970

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAETAARGRLFSGIQPTADSLHLGNVLGAVQQWVRLQHEYEALFCVVDLHAITVAQDPE
CCCCHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHEECCCHH
ELRRRTRAVVAQYVALGVDPAKSAIFVQSHVPAHAELAWVLGCLTGYGEAARMTQFKDKS
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
AKQGNDATTVGLFTYPVLMAADILLYQTNVVPVGDDQRQHLELTRDVAQRFNGRYGQTFV
CCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEE
LPETFVPKNAARIYDLQDPTVKMSKSASTPAGLINLLDEPAVSAKKVKSAQTDSDREIRF
CCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEE
DRDAKPGVSNLLSIQSALTGADIETLVDGYAGRGYGDLKKDTAEALIEFVTPVRDRTNEL
CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSDTAALDDILASGAARARELAEKTLTEVYDRIGFVRPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAETAARGRLFSGIQPTADSLHLGNVLGAVQQWVRLQHEYEALFCVVDLHAITVAQDPE
CCCHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHEECCCHH
ELRRRTRAVVAQYVALGVDPAKSAIFVQSHVPAHAELAWVLGCLTGYGEAARMTQFKDKS
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
AKQGNDATTVGLFTYPVLMAADILLYQTNVVPVGDDQRQHLELTRDVAQRFNGRYGQTFV
CCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEE
LPETFVPKNAARIYDLQDPTVKMSKSASTPAGLINLLDEPAVSAKKVKSAQTDSDREIRF
CCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEE
DRDAKPGVSNLLSIQSALTGADIETLVDGYAGRGYGDLKKDTAEALIEFVTPVRDRTNEL
CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSDTAALDDILASGAARARELAEKTLTEVYDRIGFVRPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]