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The map label for this gene is gnuT [H]

Identifier: 169630713

GI number: 169630713

Start: 3683427

End: 3684815

Strand: Reverse

Name: gnuT [H]

Synonym: MAB_3634c

Alternate gene names: 169630713

Gene position: 3684815-3683427 (Counterclockwise)

Preceding gene: 169630714

Following gene: 169630709

Centisome position: 72.72

GC content: 64.58

Gene sequence:

>1389_bases
ATGAACGCCGGGCTGGTGCTCCTGGCCGAACAGGCGAACGTCGCGCACACCACGAGTGAGGTCCGGCTGCTCGCCGCTGT
GCTGCTGAGTATCGGGGCGATCATTCTGCTCATCACCCGCCTTCGGCTGCATCCGTTCCTGGCGCTGCTGTTGGGGTCGG
GGACACTGGCTGCCGCCGCGAGCGTCCCGTTCGACAAGTTGCTGGGCTCGTTTGTGACGGGGTTCGGCTCGACCATCGCC
GGTGTTGGGCTGCTCATCGGCCTGGGTGCGATGCTCGGCCGGCTGCTGGCCGATTCCGGCGGGGCGAACATCGTGGCCGA
CGCCGTGCTCACCCGGTCCAGTCCACGTCTGCTGCCGTGGGCAGTGGCGTCGATCGCCGCCGTGCTGGGCCTGCCCTTGT
TCTTCGAAGTGGGTGTGGTGCTGTTGATTCCGATTGTGCTCTTGGTGGCACGTCGGGGAAATGTGCCACTGCTACGGGTG
GGCATCCCAGCGCTGGCGGGCCTGTCAGTACTGCATGGGCTGGTGCCGCCGCATCCGGGCCCGTTGGTGGCAGTGGATGC
GCTGAAGGCCGACCTGGGTGTCACTCTGGCATTCGGACTTGTGGCGGCGGTGCCCACCTTGATCGTGGCGGGACCGCTCT
ACGCGCGGATCGCGGAGCGCTGGGTGGGGCCGTTGGACATTCCCACCGCGACGGCGCCTGAAGCCGAGCGCACGGGGCCC
GCACCCAGCGTGGTGGCAGTGCTGGCGACCATCTTGCTACCGGTGACGCTGATGTTGGCGAAGGCGTTGTCCGATGTCGT
CATCGACAATCCGAAATCGTTGGTGCAGCGGATCTTCGATACGATCGGGACCCCACTGGTTGCGCTGTTGGCAGCGACGT
TGGTGGCCATGGTGACACTGGGCAAGGCATCGGGTCTGGATCGGATTGGTGTCGCGGGGATCATCGAGAAGTCGCTGGGA
CCCATCGCGGGAATTGTCTTCATCGTTGGTGCCGGTGGCGGATTCAAGCAGACGCTCATCGATGTCGGGGTGGGAGACGC
GGTGAGCAGTTGGTCGGAGAAATGGCAGATTCCCGCGCTGGTGCTCGGCTGGCTCATCGCGGTGCTCATTCGATTGGCCA
CCGGATCAGCCACGGTAGCCACCATTACGGCCGCCGGTATCGTCTCGCCGTTGGCCGCCGACATGTCCACCGCCCATGTC
GCGCTACTGGTACTGGCGGTGGGTGCCGGATCACTGTTCTTCTCGCACGTGAACGACGCCGGATTCTGGTTGGTCAAGGA
GTATTTCGGTATGAGTGTGGGCCAGACGCTCAAGTCGTGGTCGGTGATGGAAACGCTGATCTCGGTTGTCGGATTCGCGA
TGGTGCTGCTGCTGAGTGTCGTGGTCTGA

Upstream 100 bases:

>100_bases
ACATTCTCGAACCGCTGCAATCCGACGAGAAGGGCGTCGCACTGGATGTGGGCACCGAGCCGGAGCAATTGGTGGCAGAG
GCGTTGAGGCAGTTCGGCGT

Downstream 100 bases:

>100_bases
CGCTTTTGTCCGCGCCGATGAACTGCGACAGGCCGCGAACTTCCTGTTCAGAGCTAGATACTTAGGTACTGCGGCGCCAG
CACGATCGAGTAGAGGATGG

Product: putative gluconate permease

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALLLGSGTLAAAASVPFDKLLGSFVTGFGSTIA
GVGLLIGLGAMLGRLLADSGGANIVADAVLTRSSPRLLPWAVASIAAVLGLPLFFEVGVVLLIPIVLLVARRGNVPLLRV
GIPALAGLSVLHGLVPPHPGPLVAVDALKADLGVTLAFGLVAAVPTLIVAGPLYARIAERWVGPLDIPTATAPEAERTGP
APSVVAVLATILLPVTLMLAKALSDVVIDNPKSLVQRIFDTIGTPLVALLAATLVAMVTLGKASGLDRIGVAGIIEKSLG
PIAGIVFIVGAGGGFKQTLIDVGVGDAVSSWSEKWQIPALVLGWLIAVLIRLATGSATVATITAAGIVSPLAADMSTAHV
ALLVLAVGAGSLFFSHVNDAGFWLVKEYFGMSVGQTLKSWSVMETLISVVGFAMVLLLSVVV

Sequences:

>Translated_462_residues
MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALLLGSGTLAAAASVPFDKLLGSFVTGFGSTIA
GVGLLIGLGAMLGRLLADSGGANIVADAVLTRSSPRLLPWAVASIAAVLGLPLFFEVGVVLLIPIVLLVARRGNVPLLRV
GIPALAGLSVLHGLVPPHPGPLVAVDALKADLGVTLAFGLVAAVPTLIVAGPLYARIAERWVGPLDIPTATAPEAERTGP
APSVVAVLATILLPVTLMLAKALSDVVIDNPKSLVQRIFDTIGTPLVALLAATLVAMVTLGKASGLDRIGVAGIIEKSLG
PIAGIVFIVGAGGGFKQTLIDVGVGDAVSSWSEKWQIPALVLGWLIAVLIRLATGSATVATITAAGIVSPLAADMSTAHV
ALLVLAVGAGSLFFSHVNDAGFWLVKEYFGMSVGQTLKSWSVMETLISVVGFAMVLLLSVVV
>Mature_462_residues
MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALLLGSGTLAAAASVPFDKLLGSFVTGFGSTIA
GVGLLIGLGAMLGRLLADSGGANIVADAVLTRSSPRLLPWAVASIAAVLGLPLFFEVGVVLLIPIVLLVARRGNVPLLRV
GIPALAGLSVLHGLVPPHPGPLVAVDALKADLGVTLAFGLVAAVPTLIVAGPLYARIAERWVGPLDIPTATAPEAERTGP
APSVVAVLATILLPVTLMLAKALSDVVIDNPKSLVQRIFDTIGTPLVALLAATLVAMVTLGKASGLDRIGVAGIIEKSLG
PIAGIVFIVGAGGGFKQTLIDVGVGDAVSSWSEKWQIPALVLGWLIAVLIRLATGSATVATITAAGIVSPLAADMSTAHV
ALLVLAVGAGSLFFSHVNDAGFWLVKEYFGMSVGQTLKSWSVMETLISVVGFAMVLLLSVVV

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=441, Percent_Identity=40.3628117913832, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1790716, Length=435, Percent_Identity=39.3103448275862, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1790776, Length=445, Percent_Identity=35.2808988764045, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI2367370, Length=434, Percent_Identity=36.6359447004608, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI48994939, Length=433, Percent_Identity=34.6420323325635, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1788707, Length=453, Percent_Identity=33.5540838852097, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789097, Length=446, Percent_Identity=31.6143497757848, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46988; Mature: 46988

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALLLGSGTLAAAA
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SVPFDKLLGSFVTGFGSTIAGVGLLIGLGAMLGRLLADSGGANIVADAVLTRSSPRLLPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHH
AVASIAAVLGLPLFFEVGVVLLIPIVLLVARRGNVPLLRVGIPALAGLSVLHGLVPPHPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCC
PLVAVDALKADLGVTLAFGLVAAVPTLIVAGPLYARIAERWVGPLDIPTATAPEAERTGP
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
APSVVAVLATILLPVTLMLAKALSDVVIDNPKSLVQRIFDTIGTPLVALLAATLVAMVTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GKASGLDRIGVAGIIEKSLGPIAGIVFIVGAGGGFKQTLIDVGVGDAVSSWSEKWQIPAL
HCCCCCCHHHHHHHHHHHCCHHEEEHEEEECCCCHHHHHHHHCCCHHHHHHHHCCCCHHH
VLGWLIAVLIRLATGSATVATITAAGIVSPLAADMSTAHVALLVLAVGAGSLFFSHVNDA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GFWLVKEYFGMSVGQTLKSWSVMETLISVVGFAMVLLLSVVV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALLLGSGTLAAAA
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SVPFDKLLGSFVTGFGSTIAGVGLLIGLGAMLGRLLADSGGANIVADAVLTRSSPRLLPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHH
AVASIAAVLGLPLFFEVGVVLLIPIVLLVARRGNVPLLRVGIPALAGLSVLHGLVPPHPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCC
PLVAVDALKADLGVTLAFGLVAAVPTLIVAGPLYARIAERWVGPLDIPTATAPEAERTGP
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
APSVVAVLATILLPVTLMLAKALSDVVIDNPKSLVQRIFDTIGTPLVALLAATLVAMVTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GKASGLDRIGVAGIIEKSLGPIAGIVFIVGAGGGFKQTLIDVGVGDAVSSWSEKWQIPAL
HCCCCCCHHHHHHHHHHHCCHHEEEHEEEECCCCHHHHHHHHCCCHHHHHHHHCCCCHHH
VLGWLIAVLIRLATGSATVATITAAGIVSPLAADMSTAHVALLVLAVGAGSLFFSHVNDA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GFWLVKEYFGMSVGQTLKSWSVMETLISVVGFAMVLLLSVVV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]