Click here to switch to the map view.

The map label for this gene is mtrB [H]

Identifier: 169630670

GI number: 169630670

Start: 3639373

End: 3641103

Strand: Reverse

Name: mtrB [H]

Synonym: MAB_3590c

Alternate gene names: 169630670

Gene position: 3641103-3639373 (Counterclockwise)

Preceding gene: 169630671

Following gene: 169630669

Centisome position: 71.86

GC content: 65.45

Gene sequence:

>1731_bases
GTGATCTTCAGCTCGAAGCGGCGCATTCAGCGGCGATCGGCACCACTGGTACGCGGACTGAAGGCGCTGAGTCGAGCGGT
CGGGTTCACCTGGCGCCGTTCCCTGCAGGTGCGGGTGGTGGTGTCCAACCTGGCGCTGTCCTCCCTGGTCATCCTGATCC
TGGGATTTGTGCTCACCAGCCAGGTCACCGACCGCATCCTGGAGTCGAAGATCCGGGTGGCGACCGAGGAGATGGAACGC
GCACGCGTCATCGTCAGCGACGATGTCGGCGGTGAGGAAACCCGGTCATTACAAAGCAGTCTGGAGCTGGCCCGTAACCA
GCTGCTGAACGGCAGCAAGGGTTCTGAAGGCGGCGGCGCGGGCGCGTTCGATGCTGTTCTGCTGGTTCCCGGCGACGGCC
CCCGCGAGGCAACTTCGGCGGGACCGGCCACTCAGATTCCGGGCCCCTTGCGTGAATTCGTCAAGGCAGGCCAGGTCAGC
TACCAATACTCGACGGTCCATACCGAGAGTTTCTCGGGCAAGGCACTGGTCATCGGCTCGCCGACGACCTCGAAGGTCAC
CGCCCTCGAGCTGTACCTGGTCTTCCCACTGTCCAACGAGGAAAGCACTATTTCCCTGGTGCGCGGCACCATCGTCACCG
GTGGCGTGGTGCTGTTGGTGCTGCTGGCCGCGGCGGCGCTGCTGGTCGCTCGTCAGGTGGTGTTGCCGGTGCGGTCGGCA
TCGCGCATCGCCGAGCGTTTCGCCGAAGGACATCTGTCCGAACGGATGCCGGTGCGCGGCGTCGACGATATGGCGCGGCT
GGCGGTGTCGTTCAACGATATGGCCGAAAGCCTGTCGCGTGAGATCACCCAACTGGAAGAGTTCGGAAATCTGCAGCGCC
GCTTCACCTCTGATGTGAGCCACGAACTGCGTACGCCGCTGACCACGGTGCGGATGGCGGCCGACCTGATCTACGACAAC
CGCGAAGAGCTTGATCCGGCCCTGCAGCGGTCCGCCGAGCTGATGGTCAACGAGCTCGATCGATTCGAAACGCTGCTCGC
CGACCTGTTGGAAATCTCGCGGCACGACGCGGGTGTGGCTGAATTGGCAGTAGAGCAGGTGGATCTGCGTGACACCGTCA
AGGCGGTGGTGGCCTCTGTTCAGCACCTGGCCGACGAGCTGGATACCAGCGTCGAGCTTGACATGCCCGACAAAGAGATC
ATCGCCGAGGTGGATCCCCGCCGCGTGGAACGCATCCTGCGCAATCTGGTGGCCAATGCCATCGACCACAGCGAGCACAA
GCCCGTCACCATCCGGATGGCCGCCGATATCGACAGTGTGGCCGTCACTGTGCGCGATCGCGGTGTCGGGCTGCGTCCCG
GCGAGGAAAAGCTGGTGTTCAACAGGTTCTGGCGCGCGGATCCGTCGCGCAAGCGGCATTCCGGCGGCACCGGCCTGGGA
CTTGCCATCAGCGTCGAGGACGCCCGGTTGCACCAGGGGCGCCTGGAGGCGTGGGGCGAACCGGGTAATGGAGCGTTGTT
CCGTCTGACGGTGCCGCTGGTGCGTGGGCATAAGGTGACCACGAGTCCGCTGCCGTTGAACCCGACCAGCCGCCCGAGTT
CGGCTGTGCGACGGGCGGCTTCGCGGGGTGCTCACCCCGGCGAGCAAGAGACGACGCCCATGCGCGCCTCGGGTGCCAAA
ATCGAGCGCCCGCGGGAGTCGGCCGGCGGCCGGGCGGAGGATGCGTCGTGA

Upstream 100 bases:

>100_bases
ACGTCCACGTGCAGCGTCTGCGGGCGAAGGTCGAGAAGGACCCCGAGAATCCGACCGTGGTGTTGACCGTTCGAGGAGTG
GGATATAAGGCCGGACCCCC

Downstream 100 bases:

>100_bases
CATGCCGCAAGGTGGCCGCGGTTCTGGCGGCGGTAGCGCTCATCGTCCCCAGTTGCGCCGGCGTGCCCTCATCGTCCTCG
CCGCAGGCGATCGGCACAGT

Product: sensor histidine kinase MtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MIFSSKRRIQRRSAPLVRGLKALSRAVGFTWRRSLQVRVVVSNLALSSLVILILGFVLTSQVTDRILESKIRVATEEMER
ARVIVSDDVGGEETRSLQSSLELARNQLLNGSKGSEGGGAGAFDAVLLVPGDGPREATSAGPATQIPGPLREFVKAGQVS
YQYSTVHTESFSGKALVIGSPTTSKVTALELYLVFPLSNEESTISLVRGTIVTGGVVLLVLLAAAALLVARQVVLPVRSA
SRIAERFAEGHLSERMPVRGVDDMARLAVSFNDMAESLSREITQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADLIYDN
REELDPALQRSAELMVNELDRFETLLADLLEISRHDAGVAELAVEQVDLRDTVKAVVASVQHLADELDTSVELDMPDKEI
IAEVDPRRVERILRNLVANAIDHSEHKPVTIRMAADIDSVAVTVRDRGVGLRPGEEKLVFNRFWRADPSRKRHSGGTGLG
LAISVEDARLHQGRLEAWGEPGNGALFRLTVPLVRGHKVTTSPLPLNPTSRPSSAVRRAASRGAHPGEQETTPMRASGAK
IERPRESAGGRAEDAS

Sequences:

>Translated_576_residues
MIFSSKRRIQRRSAPLVRGLKALSRAVGFTWRRSLQVRVVVSNLALSSLVILILGFVLTSQVTDRILESKIRVATEEMER
ARVIVSDDVGGEETRSLQSSLELARNQLLNGSKGSEGGGAGAFDAVLLVPGDGPREATSAGPATQIPGPLREFVKAGQVS
YQYSTVHTESFSGKALVIGSPTTSKVTALELYLVFPLSNEESTISLVRGTIVTGGVVLLVLLAAAALLVARQVVLPVRSA
SRIAERFAEGHLSERMPVRGVDDMARLAVSFNDMAESLSREITQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADLIYDN
REELDPALQRSAELMVNELDRFETLLADLLEISRHDAGVAELAVEQVDLRDTVKAVVASVQHLADELDTSVELDMPDKEI
IAEVDPRRVERILRNLVANAIDHSEHKPVTIRMAADIDSVAVTVRDRGVGLRPGEEKLVFNRFWRADPSRKRHSGGTGLG
LAISVEDARLHQGRLEAWGEPGNGALFRLTVPLVRGHKVTTSPLPLNPTSRPSSAVRRAASRGAHPGEQETTPMRASGAK
IERPRESAGGRAEDAS
>Mature_576_residues
MIFSSKRRIQRRSAPLVRGLKALSRAVGFTWRRSLQVRVVVSNLALSSLVILILGFVLTSQVTDRILESKIRVATEEMER
ARVIVSDDVGGEETRSLQSSLELARNQLLNGSKGSEGGGAGAFDAVLLVPGDGPREATSAGPATQIPGPLREFVKAGQVS
YQYSTVHTESFSGKALVIGSPTTSKVTALELYLVFPLSNEESTISLVRGTIVTGGVVLLVLLAAAALLVARQVVLPVRSA
SRIAERFAEGHLSERMPVRGVDDMARLAVSFNDMAESLSREITQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADLIYDN
REELDPALQRSAELMVNELDRFETLLADLLEISRHDAGVAELAVEQVDLRDTVKAVVASVQHLADELDTSVELDMPDKEI
IAEVDPRRVERILRNLVANAIDHSEHKPVTIRMAADIDSVAVTVRDRGVGLRPGEEKLVFNRFWRADPSRKRHSGGTGLG
LAISVEDARLHQGRLEAWGEPGNGALFRLTVPLVRGHKVTTSPLPLNPTSRPSSAVRRAASRGAHPGEQETTPMRASGAK
IERPRESAGGRAEDAS

Specific function: Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=328, Percent_Identity=29.2682926829268, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786783, Length=378, Percent_Identity=25.3968253968254, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787894, Length=271, Percent_Identity=30.6273062730627, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=30.2521008403361, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=27.6223776223776, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI87081816, Length=437, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=28.099173553719, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789149, Length=353, Percent_Identity=26.628895184136, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1786912, Length=325, Percent_Identity=26.7692307692308, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082128, Length=306, Percent_Identity=25.4901960784314, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=299, Percent_Identity=24.7491638795987, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=27.7992277992278, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789403, Length=477, Percent_Identity=25.3668763102725, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=25.4098360655738, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=24.8868778280543, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789808, Length=307, Percent_Identity=25.4071661237785, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790551, Length=285, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=27.0386266094421, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790861, Length=280, Percent_Identity=26.7857142857143, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62619; Mature: 62619

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSSKRRIQRRSAPLVRGLKALSRAVGFTWRRSLQVRVVVSNLALSSLVILILGFVLTS
CCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHH
QVTDRILESKIRVATEEMERARVIVSDDVGGEETRSLQSSLELARNQLLNGSKGSEGGGA
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GAFDAVLLVPGDGPREATSAGPATQIPGPLREFVKAGQVSYQYSTVHTESFSGKALVIGS
CCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEC
PTTSKVTALELYLVFPLSNEESTISLVRGTIVTGGVVLLVLLAAAALLVARQVVLPVRSA
CCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRIAERFAEGHLSERMPVRGVDDMARLAVSFNDMAESLSREITQLEEFGNLQRRFTSDVS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPLTTVRMAADLIYDNREELDPALQRSAELMVNELDRFETLLADLLEISRHDAGVA
HHHHCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELAVEQVDLRDTVKAVVASVQHLADELDTSVELDMPDKEIIAEVDPRRVERILRNLVANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHCCCHHHHHHHHHHHHHHH
IDHSEHKPVTIRMAADIDSVAVTVRDRGVGLRPGEEKLVFNRFWRADPSRKRHSGGTGLG
HCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCCEE
LAISVEDARLHQGRLEAWGEPGNGALFRLTVPLVRGHKVTTSPLPLNPTSRPSSAVRRAA
EEEEECHHHHHCCHHHCCCCCCCCEEEEEEEEHHCCCEEECCCCCCCCCCCHHHHHHHHH
SRGAHPGEQETTPMRASGAKIERPRESAGGRAEDAS
HCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MIFSSKRRIQRRSAPLVRGLKALSRAVGFTWRRSLQVRVVVSNLALSSLVILILGFVLTS
CCCCHHHHHHHHCCHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHH
QVTDRILESKIRVATEEMERARVIVSDDVGGEETRSLQSSLELARNQLLNGSKGSEGGGA
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GAFDAVLLVPGDGPREATSAGPATQIPGPLREFVKAGQVSYQYSTVHTESFSGKALVIGS
CCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEC
PTTSKVTALELYLVFPLSNEESTISLVRGTIVTGGVVLLVLLAAAALLVARQVVLPVRSA
CCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRIAERFAEGHLSERMPVRGVDDMARLAVSFNDMAESLSREITQLEEFGNLQRRFTSDVS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPLTTVRMAADLIYDNREELDPALQRSAELMVNELDRFETLLADLLEISRHDAGVA
HHHHCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELAVEQVDLRDTVKAVVASVQHLADELDTSVELDMPDKEIIAEVDPRRVERILRNLVANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHCCCHHHHHHHHHHHHHHH
IDHSEHKPVTIRMAADIDSVAVTVRDRGVGLRPGEEKLVFNRFWRADPSRKRHSGGTGLG
HCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCCEE
LAISVEDARLHQGRLEAWGEPGNGALFRLTVPLVRGHKVTTSPLPLNPTSRPSSAVRRAA
EEEEECHHHHHCCHHHCCCCCCCCEEEEEEEEHHCCCEEECCCCCCCCCCCHHHHHHHHH
SRGAHPGEQETTPMRASGAKIERPRESAGGRAEDAS
HCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA