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The map label for this gene is mmpL4 [H]

Identifier: 169630642

GI number: 169630642

Start: 3605444

End: 3608299

Strand: Reverse

Name: mmpL4 [H]

Synonym: MAB_3562c

Alternate gene names: 169630642

Gene position: 3608299-3605444 (Counterclockwise)

Preceding gene: 169630643

Following gene: 169630641

Centisome position: 71.21

GC content: 59.84

Gene sequence:

>2856_bases
ATGAGTAACCACGAGATGCCCACGGGCCCGATACCGGTCAGGCGTCCGTTGGTTCCGCGCATGGTCCGCGTCCTTGCGGT
GCCGATCATCGTCTTCTGGGCGTTCCTGGCTGTGACGACCAATACCTTTGTGCCGCAGGTTGAAAAGGTTGCCGAGGAAC
TCGCTGGGCCGATGATTCCCCACTACGCGCCGTCGCAGCGTGCCATGTTGCATATCGGCGAAAAGTTCCAGGAATCAACG
TCGACGAGCCTGACGATGGTTGTGCTGGAATCGCAGGATCGTGTGCTCGGAGACGAGGATCATCGCTACTACGACGAGCT
GATGCAGAGGTTCAAGGACGATAGCGAGCACGTTCAGTATGTGATGGACCTGTGGGGGAAATCGATCACATCGGCTGGCG
CGCAAAGCATCGACGGCAAGTCCACCTATGTGCTGTTGCGCCTGGCCGGTGACATAGGCCAGATGCAGGCCAACGAGTCC
GTCCGGGCGGTGCGCGCCATCGTCGACAAGCAGACGCCACCAGCGGGTCTCCGGGTGTACGTGAGCGGACCTGCGCCATT
GGCCGGTGACACCCTGGACATCGCGAATTCGAGCCTGAACAACATCACCATCATCACCATCATCCTCATCATCGTGATGC
TGTTGCTGGTGTATCGCTCCTTCTCGACGCTGTTGTTGCCGCTGGCCGGTGTGCTGATCGAAATGCTTGTCACCAAGGGC
GTCATCGCGACGCTCGGGCACCTGGGGTACATCGAACTATCGTCGTTCGCGGTCAACATAGTGGTCTCGCTGACGCTGGG
CGCGGGCACCGACTACGGCATTTTCCTTTTGGGGCGATACCACGAGGCACGGTCCACGGGCCAGAGTCGTGAGGAGGCCT
ATTACACGGCGTACCGCGGTGTGGCGCCGGTCGTTATCGGATCCGGTTTGACCATCGCGGGAGCCTGCTATTGCCTGAGC
TTTGCCCGGCTGAATTATTTCCACACCATGGGGCCCGCGGTGGCCATCGCCATGGTGCTCACCATCGCGGCGGCCCTTAC
CCTGGTGCCGGCCGTGCTCACCGTCGGGAGTTTGTTCGGGCTATTCGACCCGAAGGCAAAAGCGAAGGCGCAGTTGTATC
GTCGCATCGGAGCCAGTGTGGTGCGCTGGCCGGTGCCGATCTTTGTGGCAAGCAGCATTATCGTCATGGTGGGTGCGGTC
TTCGTGCCCACGTACCAGGTCAGTTACGACGACCGTGCCTATCAACCAGCCGGCGCGCCGGCCAATCAGGGCTTCGCGGC
GGCGGACCGGCATTTTTCCAAGAGCAAGCTCTTCACCGAGATGCTGATGGTCGAGTCCGACCACGATATGCGAAATTCTG
CCGACTTCATCTCCTTGGATCGGGTGGCTAAGAGCCTCGTGCGCCTTCCCGGCGTGTCGATGGTACAGAGCATCACCCGT
CCGCTGGGCAGGCCACTGGAACATGCCACGCTCCCTTATCTTTTCACCACGCAGGGCAGTGGCAATGGTCAGCAGCTCCC
GTTCACCAAGCGGCAGAACGGCAATACCGCGCAGCAAGCCGAGATCATGGGGAACACCATTGTGGTGCTGCGGGACATGA
TTGACCTCACCCAGAAACTCACCGATGCGATGCACGCGACGGTCGTCACGATGGAGGACATGCAGCAGGTCACCGAGGCG
ATGGATCAGTACGTTTCGAATCTCGACGACTTCATGCGGCCGCTGCGTAACTACTTCTATTGGGAACCGCACTGCTTTGA
CATCCCCGCGTGCTGGGCCTTCCGGTCGCTGTTCGACATGCTTGACAGCGTCGACAAACTAGCGGCCGACATCAAGGACG
CTGTCGCCCAGCTTGAAATTGTGGACAAGCTGCTGCCGCAAATGGTTTCGCAGCTGAAGGTGATGGCCAACGATATGGAG
GGCATCAGGGCGCTCATCATCAACACGTACGGAACTTCCGACCTGCAGTCAACGCTGACCACGCAGACATTCGACGACAT
GATCAATGTGGGTCTCGACTTCGACAAATCCCGCAGTGACGACTTCTTCTACATCCCCCGACAGGGCTTCGAGAACGAAG
ACGTCAAGACCGGGATGCAGCTGCTGATGTCGCCCGACGGTATGGCCGCGCGGTTCATGATCACGCATGAGGGCAACGCG
ATGGGTCCCGAGGGTGTCGAACACGTCGAGCAGTTCCCGGAGGCGGTGGGCCTGGCGTTGAAGGAGACCTCACTGGCGGG
TGCGAGGGTCTATGTCGGTGGCGCAGGCTCGAACGACAAGGACATCAAAGAGTACGGCGCATCCGATCTGCTTATTGTGG
CGATCGCCGCATTCGTCTTGATCTTCTTGATCATGATGTTCCTGACCCGAAGCTTGATGGCGCCCTTTGTGATCATCGGC
ACGGTCGCCTTTTCCTACAGTGGCGCGTTCGGTCTGTCGGTGCTTATCTGGCAGCACCTCATCGGCTTGCCGCTGCATTG
GCTGGTGTTACCGCTGACATTCATCATCCTGGTCGCGGTGGGGTCGGACTACAACCTGCTTTTGGTCGCGCGATTGAAAG
AAGAGACCGGGGCCGGACTCAACACCGGCCTGATCCGGGCGCTCGGCAGCACCGGGGCAGTGGTGACATCGGCCGGTCTG
GTCTTCGCGTTCACCATGTTGGCCATGCTCGCCAGTGACTTGCGCACGATCGGCCAGGTCGGTTCGACGATATGCATTGG
CTTGCTGCTCGACACCTTGATCGTGCGATCGTTTATCGTCCCGTCGTTGGTGCGGCTTTTCGGAACTTGGTTCTGGTGGC
CGACAAGGGTTTTCGCTCGCCCCTTACGGCGACAGAATGTAGGAGCGCACCGGTGA

Upstream 100 bases:

>100_bases
GCGGTGAGGTCGGTTGCCGAATCTTGGTCAATGACGTTGTCCGAGATGAGAAGTTCGACGATCATCACGACGCTGACGTC
ACGTGCAGGGTCAAGTCGGT

Downstream 100 bases:

>100_bases
TCTCATACGCAACCCTGACGGTGCTGGCAGCCGTAGTCGAGGTAGTGCTGGTTGTGTGCGTGTTCGTATACGTGAGGCGT
TTGCAGCGGCGGCACACCAC

Product: MmpL family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 951; Mature: 950

Protein sequence:

>951_residues
MSNHEMPTGPIPVRRPLVPRMVRVLAVPIIVFWAFLAVTTNTFVPQVEKVAEELAGPMIPHYAPSQRAMLHIGEKFQEST
STSLTMVVLESQDRVLGDEDHRYYDELMQRFKDDSEHVQYVMDLWGKSITSAGAQSIDGKSTYVLLRLAGDIGQMQANES
VRAVRAIVDKQTPPAGLRVYVSGPAPLAGDTLDIANSSLNNITIITIILIIVMLLLVYRSFSTLLLPLAGVLIEMLVTKG
VIATLGHLGYIELSSFAVNIVVSLTLGAGTDYGIFLLGRYHEARSTGQSREEAYYTAYRGVAPVVIGSGLTIAGACYCLS
FARLNYFHTMGPAVAIAMVLTIAAALTLVPAVLTVGSLFGLFDPKAKAKAQLYRRIGASVVRWPVPIFVASSIIVMVGAV
FVPTYQVSYDDRAYQPAGAPANQGFAAADRHFSKSKLFTEMLMVESDHDMRNSADFISLDRVAKSLVRLPGVSMVQSITR
PLGRPLEHATLPYLFTTQGSGNGQQLPFTKRQNGNTAQQAEIMGNTIVVLRDMIDLTQKLTDAMHATVVTMEDMQQVTEA
MDQYVSNLDDFMRPLRNYFYWEPHCFDIPACWAFRSLFDMLDSVDKLAADIKDAVAQLEIVDKLLPQMVSQLKVMANDME
GIRALIINTYGTSDLQSTLTTQTFDDMINVGLDFDKSRSDDFFYIPRQGFENEDVKTGMQLLMSPDGMAARFMITHEGNA
MGPEGVEHVEQFPEAVGLALKETSLAGARVYVGGAGSNDKDIKEYGASDLLIVAIAAFVLIFLIMMFLTRSLMAPFVIIG
TVAFSYSGAFGLSVLIWQHLIGLPLHWLVLPLTFIILVAVGSDYNLLLVARLKEETGAGLNTGLIRALGSTGAVVTSAGL
VFAFTMLAMLASDLRTIGQVGSTICIGLLLDTLIVRSFIVPSLVRLFGTWFWWPTRVFARPLRRQNVGAHR

Sequences:

>Translated_951_residues
MSNHEMPTGPIPVRRPLVPRMVRVLAVPIIVFWAFLAVTTNTFVPQVEKVAEELAGPMIPHYAPSQRAMLHIGEKFQEST
STSLTMVVLESQDRVLGDEDHRYYDELMQRFKDDSEHVQYVMDLWGKSITSAGAQSIDGKSTYVLLRLAGDIGQMQANES
VRAVRAIVDKQTPPAGLRVYVSGPAPLAGDTLDIANSSLNNITIITIILIIVMLLLVYRSFSTLLLPLAGVLIEMLVTKG
VIATLGHLGYIELSSFAVNIVVSLTLGAGTDYGIFLLGRYHEARSTGQSREEAYYTAYRGVAPVVIGSGLTIAGACYCLS
FARLNYFHTMGPAVAIAMVLTIAAALTLVPAVLTVGSLFGLFDPKAKAKAQLYRRIGASVVRWPVPIFVASSIIVMVGAV
FVPTYQVSYDDRAYQPAGAPANQGFAAADRHFSKSKLFTEMLMVESDHDMRNSADFISLDRVAKSLVRLPGVSMVQSITR
PLGRPLEHATLPYLFTTQGSGNGQQLPFTKRQNGNTAQQAEIMGNTIVVLRDMIDLTQKLTDAMHATVVTMEDMQQVTEA
MDQYVSNLDDFMRPLRNYFYWEPHCFDIPACWAFRSLFDMLDSVDKLAADIKDAVAQLEIVDKLLPQMVSQLKVMANDME
GIRALIINTYGTSDLQSTLTTQTFDDMINVGLDFDKSRSDDFFYIPRQGFENEDVKTGMQLLMSPDGMAARFMITHEGNA
MGPEGVEHVEQFPEAVGLALKETSLAGARVYVGGAGSNDKDIKEYGASDLLIVAIAAFVLIFLIMMFLTRSLMAPFVIIG
TVAFSYSGAFGLSVLIWQHLIGLPLHWLVLPLTFIILVAVGSDYNLLLVARLKEETGAGLNTGLIRALGSTGAVVTSAGL
VFAFTMLAMLASDLRTIGQVGSTICIGLLLDTLIVRSFIVPSLVRLFGTWFWWPTRVFARPLRRQNVGAHR
>Mature_950_residues
SNHEMPTGPIPVRRPLVPRMVRVLAVPIIVFWAFLAVTTNTFVPQVEKVAEELAGPMIPHYAPSQRAMLHIGEKFQESTS
TSLTMVVLESQDRVLGDEDHRYYDELMQRFKDDSEHVQYVMDLWGKSITSAGAQSIDGKSTYVLLRLAGDIGQMQANESV
RAVRAIVDKQTPPAGLRVYVSGPAPLAGDTLDIANSSLNNITIITIILIIVMLLLVYRSFSTLLLPLAGVLIEMLVTKGV
IATLGHLGYIELSSFAVNIVVSLTLGAGTDYGIFLLGRYHEARSTGQSREEAYYTAYRGVAPVVIGSGLTIAGACYCLSF
ARLNYFHTMGPAVAIAMVLTIAAALTLVPAVLTVGSLFGLFDPKAKAKAQLYRRIGASVVRWPVPIFVASSIIVMVGAVF
VPTYQVSYDDRAYQPAGAPANQGFAAADRHFSKSKLFTEMLMVESDHDMRNSADFISLDRVAKSLVRLPGVSMVQSITRP
LGRPLEHATLPYLFTTQGSGNGQQLPFTKRQNGNTAQQAEIMGNTIVVLRDMIDLTQKLTDAMHATVVTMEDMQQVTEAM
DQYVSNLDDFMRPLRNYFYWEPHCFDIPACWAFRSLFDMLDSVDKLAADIKDAVAQLEIVDKLLPQMVSQLKVMANDMEG
IRALIINTYGTSDLQSTLTTQTFDDMINVGLDFDKSRSDDFFYIPRQGFENEDVKTGMQLLMSPDGMAARFMITHEGNAM
GPEGVEHVEQFPEAVGLALKETSLAGARVYVGGAGSNDKDIKEYGASDLLIVAIAAFVLIFLIMMFLTRSLMAPFVIIGT
VAFSYSGAFGLSVLIWQHLIGLPLHWLVLPLTFIILVAVGSDYNLLLVARLKEETGAGLNTGLIRALGSTGAVVTSAGLV
FAFTMLAMLASDLRTIGQVGSTICIGLLLDTLIVRSFIVPSLVRLFGTWFWWPTRVFARPLRRQNVGAHR

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 104232; Mature: 104100

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHEMPTGPIPVRRPLVPRMVRVLAVPIIVFWAFLAVTTNTFVPQVEKVAEELAGPMIP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HYAPSQRAMLHIGEKFQESTSTSLTMVVLESQDRVLGDEDHRYYDELMQRFKDDSEHVQY
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
VMDLWGKSITSAGAQSIDGKSTYVLLRLAGDIGQMQANESVRAVRAIVDKQTPPAGLRVY
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHCCCCCCCEEEE
VSGPAPLAGDTLDIANSSLNNITIITIILIIVMLLLVYRSFSTLLLPLAGVLIEMLVTKG
ECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIATLGHLGYIELSSFAVNIVVSLTLGAGTDYGIFLLGRYHEARSTGQSREEAYYTAYRG
HHHHHHCCCHHHHHHHHEEEEEEEEECCCCCCCEEEEECHHHHHCCCCHHHHHHHHHHCC
VAPVVIGSGLTIAGACYCLSFARLNYFHTMGPAVAIAMVLTIAAALTLVPAVLTVGSLFG
CCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFDPKAKAKAQLYRRIGASVVRWPVPIFVASSIIVMVGAVFVPTYQVSYDDRAYQPAGAP
CCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
ANQGFAAADRHFSKSKLFTEMLMVESDHDMRNSADFISLDRVAKSLVRLPGVSMVQSITR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
PLGRPLEHATLPYLFTTQGSGNGQQLPFTKRQNGNTAQQAEIMGNTIVVLRDMIDLTQKL
HHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
TDAMHATVVTMEDMQQVTEAMDQYVSNLDDFMRPLRNYFYWEPHCFDIPACWAFRSLFDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LDSVDKLAADIKDAVAQLEIVDKLLPQMVSQLKVMANDMEGIRALIINTYGTSDLQSTLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
TQTFDDMINVGLDFDKSRSDDFFYIPRQGFENEDVKTGMQLLMSPDGMAARFMITHEGNA
HHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCC
MGPEGVEHVEQFPEAVGLALKETSLAGARVYVGGAGSNDKDIKEYGASDLLIVAIAAFVL
CCCHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHH
IFLIMMFLTRSLMAPFVIIGTVAFSYSGAFGLSVLIWQHLIGLPLHWLVLPLTFIILVAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GSDYNLLLVARLKEETGAGLNTGLIRALGSTGAVVTSAGLVFAFTMLAMLASDLRTIGQV
CCCCCEEEEEEEHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSTICIGLLLDTLIVRSFIVPSLVRLFGTWFWWPTRVFARPLRRQNVGAHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNHEMPTGPIPVRRPLVPRMVRVLAVPIIVFWAFLAVTTNTFVPQVEKVAEELAGPMIP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HYAPSQRAMLHIGEKFQESTSTSLTMVVLESQDRVLGDEDHRYYDELMQRFKDDSEHVQY
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
VMDLWGKSITSAGAQSIDGKSTYVLLRLAGDIGQMQANESVRAVRAIVDKQTPPAGLRVY
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHCCCCCCCEEEE
VSGPAPLAGDTLDIANSSLNNITIITIILIIVMLLLVYRSFSTLLLPLAGVLIEMLVTKG
ECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIATLGHLGYIELSSFAVNIVVSLTLGAGTDYGIFLLGRYHEARSTGQSREEAYYTAYRG
HHHHHHCCCHHHHHHHHEEEEEEEEECCCCCCCEEEEECHHHHHCCCCHHHHHHHHHHCC
VAPVVIGSGLTIAGACYCLSFARLNYFHTMGPAVAIAMVLTIAAALTLVPAVLTVGSLFG
CCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFDPKAKAKAQLYRRIGASVVRWPVPIFVASSIIVMVGAVFVPTYQVSYDDRAYQPAGAP
CCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
ANQGFAAADRHFSKSKLFTEMLMVESDHDMRNSADFISLDRVAKSLVRLPGVSMVQSITR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
PLGRPLEHATLPYLFTTQGSGNGQQLPFTKRQNGNTAQQAEIMGNTIVVLRDMIDLTQKL
HHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
TDAMHATVVTMEDMQQVTEAMDQYVSNLDDFMRPLRNYFYWEPHCFDIPACWAFRSLFDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LDSVDKLAADIKDAVAQLEIVDKLLPQMVSQLKVMANDMEGIRALIINTYGTSDLQSTLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
TQTFDDMINVGLDFDKSRSDDFFYIPRQGFENEDVKTGMQLLMSPDGMAARFMITHEGNA
HHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCC
MGPEGVEHVEQFPEAVGLALKETSLAGARVYVGGAGSNDKDIKEYGASDLLIVAIAAFVL
CCCHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHH
IFLIMMFLTRSLMAPFVIIGTVAFSYSGAFGLSVLIWQHLIGLPLHWLVLPLTFIILVAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GSDYNLLLVARLKEETGAGLNTGLIRALGSTGAVVTSAGLVFAFTMLAMLASDLRTIGQV
CCCCCEEEEEEEHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSTICIGLLLDTLIVRSFIVPSLVRLFGTWFWWPTRVFARPLRRQNVGAHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]