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The map label for this gene is ubiB [C]

Identifier: 169630585

GI number: 169630585

Start: 3546669

End: 3548021

Strand: Direct

Name: ubiB [C]

Synonym: MAB_3504

Alternate gene names: 169630585

Gene position: 3546669-3548021 (Clockwise)

Preceding gene: 169630584

Following gene: 169630588

Centisome position: 69.99

GC content: 64.01

Gene sequence:

>1353_bases
ATGGCTGAGATTCGTCGTGGCCGCGCCGCGCGCGCCGCAAAACTCGCATCGCTTCCGGCCGGTATTGCCGGTCGTGCCGC
GCTCGGTGTCGGGAAACGGCTGACCGGTAAGTCCAAGGACGAGGTCAACGCCGAGATGATGGAGAAGGCGGCCGAACAGC
TGTTCCAGGTGCTCGGCGAGCTCAAGGGCGCGGCCATGAAACTGGGCCAGGCGCTGTCGGTGTTCGAAGCCGCCATTCCC
CCGGCCTTCGCCGAACCCTTCCGCGAGGCCCTGACCAAGCTGCAAAGCGACGCCCCACCGCTGCCCGCGGACAAGGTCCA
TCGGGTCCTCGACGCGCAGCTCGGCACCAAATGGCGTGAACGCTTCCAGTCCTTCGACGACAAGCCGGTCGCCTCGGCCA
GCATCGGGCAAGTGCACCGCGCCGTGTGGAGCGATGGGCGCGTGGTCGCCGTCAAGGTGCAATACCCGGGCGCCGACGAG
GCGGTGCGCTCGGACTTGAAGACCATGCAGCGGCTCTCGTCATTGTTCAAGCAGATCGTGCCCGGCGCAGACGTCAAAAG
CATCATCGATGAGCTGATCGAGCGCACCGAGGAAGAACTCGACTACCGCATCGAAGCCACCAACCAACGAGCCTTCGCCA
AGGCCTTCAAAGGCGACCCGGAGTTCTACGTGTCACCGGTTGTGGCCTCGGCCCCCAAGGTCGTCATCAGTGAATGGATG
CAGGGCCGGAAGCTCTCCGAAATCATCGGCAGTGGGACCGAAGACGAGCGCAATGAGTGCGGACGCCTGCTCCTTAAGTT
CACCGTCAGCTCCCCCTATCGCTGCGGACTGCTACACGCAGACACCCACCCTGGAAACTTCATGCTGCTGCCCGACGGAC
GCCTCGGCGTCATGGACTTCGGCGCCTGCGCCACCCACGAGGGTGGATTCCCGCCCAACCTGGGGCCCATCTGGCGGCTG
GAACGTGACGGAATGTGGGATGAACTGATCCCTCTCATGCGTGCGGAAGGATTCATCCCGCCGCACACCGAGGTGTCCCC
CGAGGAGATCGACGAGTACCTCAAGCCATTCATCGATCCGCTCAAATCCGATGAGTTCCACTTCACCCGGAAATGGATGC
AGCGGGTGGCTGCCAAATCCAGCGATGTGCGCGGCGCCCAGTTCCAGACGGGCCGGCATCTGGACCTGCCTCCCGTCTAC
CTGATGATGTTCCGGGTGCTGGGCAGCCTGTCCGGCATTCTGGCCCAACTCGACGCGACAATCCCCTATGCGCGAATCAT
CGGCGACTGGGTTCCCGGCTTCCGCGAGGATGAAGACCGAATGCCCGTGGCTCCCGGGGGCATTCGGTCTTAA

Upstream 100 bases:

>100_bases
TTCCCGGCTTCCACGAGGACAGCAAGGCCCCAGCCGCCACCTAGCCCAAGAGGAAAACCTGCGTTGTCAGAATCATCCGG
GCCCCGGCATGATGTAACTC

Downstream 100 bases:

>100_bases
CTGCACCCGCTAGGCGCTCGCCAAGCGAGCGAGTTCGGCGTCCTGTTCGGGCGATCCACCGGAAGCTCCGAGCCCGCCGA
TCAACGCGCCGGCTTGGTCG

Product: ABC transporter ATP-binding protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MAEIRRGRAARAAKLASLPAGIAGRAALGVGKRLTGKSKDEVNAEMMEKAAEQLFQVLGELKGAAMKLGQALSVFEAAIP
PAFAEPFREALTKLQSDAPPLPADKVHRVLDAQLGTKWRERFQSFDDKPVASASIGQVHRAVWSDGRVVAVKVQYPGADE
AVRSDLKTMQRLSSLFKQIVPGADVKSIIDELIERTEEELDYRIEATNQRAFAKAFKGDPEFYVSPVVASAPKVVISEWM
QGRKLSEIIGSGTEDERNECGRLLLKFTVSSPYRCGLLHADTHPGNFMLLPDGRLGVMDFGACATHEGGFPPNLGPIWRL
ERDGMWDELIPLMRAEGFIPPHTEVSPEEIDEYLKPFIDPLKSDEFHFTRKWMQRVAAKSSDVRGAQFQTGRHLDLPPVY
LMMFRVLGSLSGILAQLDATIPYARIIGDWVPGFREDEDRMPVAPGGIRS

Sequences:

>Translated_450_residues
MAEIRRGRAARAAKLASLPAGIAGRAALGVGKRLTGKSKDEVNAEMMEKAAEQLFQVLGELKGAAMKLGQALSVFEAAIP
PAFAEPFREALTKLQSDAPPLPADKVHRVLDAQLGTKWRERFQSFDDKPVASASIGQVHRAVWSDGRVVAVKVQYPGADE
AVRSDLKTMQRLSSLFKQIVPGADVKSIIDELIERTEEELDYRIEATNQRAFAKAFKGDPEFYVSPVVASAPKVVISEWM
QGRKLSEIIGSGTEDERNECGRLLLKFTVSSPYRCGLLHADTHPGNFMLLPDGRLGVMDFGACATHEGGFPPNLGPIWRL
ERDGMWDELIPLMRAEGFIPPHTEVSPEEIDEYLKPFIDPLKSDEFHFTRKWMQRVAAKSSDVRGAQFQTGRHLDLPPVY
LMMFRVLGSLSGILAQLDATIPYARIIGDWVPGFREDEDRMPVAPGGIRS
>Mature_449_residues
AEIRRGRAARAAKLASLPAGIAGRAALGVGKRLTGKSKDEVNAEMMEKAAEQLFQVLGELKGAAMKLGQALSVFEAAIPP
AFAEPFREALTKLQSDAPPLPADKVHRVLDAQLGTKWRERFQSFDDKPVASASIGQVHRAVWSDGRVVAVKVQYPGADEA
VRSDLKTMQRLSSLFKQIVPGADVKSIIDELIERTEEELDYRIEATNQRAFAKAFKGDPEFYVSPVVASAPKVVISEWMQ
GRKLSEIIGSGTEDERNECGRLLLKFTVSSPYRCGLLHADTHPGNFMLLPDGRLGVMDFGACATHEGGFPPNLGPIWRLE
RDGMWDELIPLMRAEGFIPPHTEVSPEEIDEYLKPFIDPLKSDEFHFTRKWMQRVAAKSSDVRGAQFQTGRHLDLPPVYL
MMFRVLGSLSGILAQLDATIPYARIIGDWVPGFREDEDRMPVAPGGIRS

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=315, Percent_Identity=29.8412698412698, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI27363457, Length=261, Percent_Identity=29.8850574712644, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI40254938, Length=294, Percent_Identity=27.2108843537415, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI217416386, Length=225, Percent_Identity=28.4444444444444, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI41393593, Length=287, Percent_Identity=27.8745644599303, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI217035081, Length=216, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI2367309, Length=253, Percent_Identity=27.6679841897233, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32565180, Length=347, Percent_Identity=29.6829971181556, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17559152, Length=295, Percent_Identity=27.7966101694915, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=302, Percent_Identity=26.8211920529801, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323282, Length=273, Percent_Identity=25.2747252747253, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI18859849, Length=293, Percent_Identity=29.6928327645051, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI22024280, Length=280, Percent_Identity=29.2857142857143, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24662575, Length=259, Percent_Identity=28.1853281853282, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 49734; Mature: 49602

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIRRGRAARAAKLASLPAGIAGRAALGVGKRLTGKSKDEVNAEMMEKAAEQLFQVLGE
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKGAAMKLGQALSVFEAAIPPAFAEPFREALTKLQSDAPPLPADKVHRVLDAQLGTKWRE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHH
RFQSFDDKPVASASIGQVHRAVWSDGRVVAVKVQYPGADEAVRSDLKTMQRLSSLFKQIV
HHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
PGADVKSIIDELIERTEEELDYRIEATNQRAFAKAFKGDPEFYVSPVVASAPKVVISEWM
CCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHCCCCCEEECCHHHCCHHHHHHHHH
QGRKLSEIIGSGTEDERNECGRLLLKFTVSSPYRCGLLHADTHPGNFMLLPDGRLGVMDF
CCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEECEEECCCCCCCEEEECCCCCCCEEC
GACATHEGGFPPNLGPIWRLERDGMWDELIPLMRAEGFIPPHTEVSPEEIDEYLKPFIDP
CCHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LKSDEFHFTRKWMQRVAAKSSDVRGAQFQTGRHLDLPPVYLMMFRVLGSLSGILAQLDAT
HCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
IPYARIIGDWVPGFREDEDRMPVAPGGIRS
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEIRRGRAARAAKLASLPAGIAGRAALGVGKRLTGKSKDEVNAEMMEKAAEQLFQVLGE
CCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKGAAMKLGQALSVFEAAIPPAFAEPFREALTKLQSDAPPLPADKVHRVLDAQLGTKWRE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHH
RFQSFDDKPVASASIGQVHRAVWSDGRVVAVKVQYPGADEAVRSDLKTMQRLSSLFKQIV
HHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
PGADVKSIIDELIERTEEELDYRIEATNQRAFAKAFKGDPEFYVSPVVASAPKVVISEWM
CCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHCCCCCEEECCHHHCCHHHHHHHHH
QGRKLSEIIGSGTEDERNECGRLLLKFTVSSPYRCGLLHADTHPGNFMLLPDGRLGVMDF
CCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEECEEECCCCCCCEEEECCCCCCCEEC
GACATHEGGFPPNLGPIWRLERDGMWDELIPLMRAEGFIPPHTEVSPEEIDEYLKPFIDP
CCHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LKSDEFHFTRKWMQRVAAKSSDVRGAQFQTGRHLDLPPVYLMMFRVLGSLSGILAQLDAT
HCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
IPYARIIGDWVPGFREDEDRMPVAPGGIRS
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]