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The map label for this gene is sigC [H]

Identifier: 169630509

GI number: 169630509

Start: 3473766

End: 3474317

Strand: Reverse

Name: sigC [H]

Synonym: MAB_3428c

Alternate gene names: 169630509

Gene position: 3474317-3473766 (Counterclockwise)

Preceding gene: 169630511

Following gene: 169630507

Centisome position: 68.57

GC content: 67.39

Gene sequence:

>552_bases
GTGGCCACCGGCACCGACGACGAGCAGCTGCTTGAGCTTGCGCTGTCCGCTGGCCGTGGCGACCAGTCCGCGCTCGAATC
TTTGGTCAAGGCGACCCAGGGCGACGTGTGGCGATTCGTTGCCTACCTGGCTGATTCCGGCGTCGCCGACGACCTTACCC
AAGAGACATATCTCAGGGCTCTCGGCGCTCTACCGCGCTTCGCTGGGCGCTCGACGGTGCGCACCTGGCTGCTGTCGATC
GCGCGCCGGGTGGTGGCCGACCATATTCGTCATCTGAAGTCCCGGCCGCGCATCGCACATGGTGCAGACCTCGAGGAAGC
TTCGCTGCGCCGCCCCACGCACCGGTTCGAGGAGCTGGTGGAGCTCAAGTCGCTGCTGGCCGCGCTTGACGATGACCGGC
GCGAGGCGTTGGTGCTGACCCAGGTGGTCGGCTTGTCGTACGCCGAGACAGCCGATGTCTGCGGCTGTGCCATCGGCACC
ATTCGTTCGCGGGTAGCCCGGGCCCGTGACGAGCTGATCGGCTGGGCCGAGCCCGAGAACCTGACCGGCTAG

Upstream 100 bases:

>100_bases
GGGCCGGTCCTCGGTATAAGTCACGGGATATTGGTCGGATGAATCGGTTAAAGAGTTCCCGCTGTTCACCCCCGAACGTC
TACGACATAGAGTAGGACTC

Downstream 100 bases:

>100_bases
AGCGACGAGCGCTCGGCGGTCGGCCTCCATTCCCACCCCGTGCGCCGCTTAGAGCCCGGCTACCGCACTGGCGATCGGCG
CGGTCCCTTCGGTCAGGAAC

Product: RNA polymerase sigma-C factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MATGTDDEQLLELALSAGRGDQSALESLVKATQGDVWRFVAYLADSGVADDLTQETYLRALGALPRFAGRSTVRTWLLSI
ARRVVADHIRHLKSRPRIAHGADLEEASLRRPTHRFEELVELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGT
IRSRVARARDELIGWAEPENLTG

Sequences:

>Translated_183_residues
MATGTDDEQLLELALSAGRGDQSALESLVKATQGDVWRFVAYLADSGVADDLTQETYLRALGALPRFAGRSTVRTWLLSI
ARRVVADHIRHLKSRPRIAHGADLEEASLRRPTHRFEELVELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGT
IRSRVARARDELIGWAEPENLTG
>Mature_182_residues
ATGTDDEQLLELALSAGRGDQSALESLVKATQGDVWRFVAYLADSGVADDLTQETYLRALGALPRFAGRSTVRTWLLSIA
RRVVADHIRHLKSRPRIAHGADLEEASLRRPTHRFEELVELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGTI
RSRVARARDELIGWAEPENLTG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=190, Percent_Identity=31.0526315789474, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20064; Mature: 19933

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGTDDEQLLELALSAGRGDQSALESLVKATQGDVWRFVAYLADSGVADDLTQETYLRA
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LGALPRFAGRSTVRTWLLSIARRVVADHIRHLKSRPRIAHGADLEEASLRRPTHRFEELV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHH
ELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGTIRSRVARARDELIGWAEPEN
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LTG
CCC
>Mature Secondary Structure 
ATGTDDEQLLELALSAGRGDQSALESLVKATQGDVWRFVAYLADSGVADDLTQETYLRA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LGALPRFAGRSTVRTWLLSIARRVVADHIRHLKSRPRIAHGADLEEASLRRPTHRFEELV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHH
ELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGTIRSRVARARDELIGWAEPEN
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LTG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]