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The map label for this gene is yciC [H]

Identifier: 169630506

GI number: 169630506

Start: 3471021

End: 3472013

Strand: Reverse

Name: yciC [H]

Synonym: MAB_3425c

Alternate gene names: 169630506

Gene position: 3472013-3471021 (Counterclockwise)

Preceding gene: 169630507

Following gene: 169630505

Centisome position: 68.52

GC content: 63.54

Gene sequence:

>993_bases
TTGATCCCGGTCACCATCGTCTCCGGGTTCTTGGGTGCCGGTAAGACGACACTGCTGAACAATCTGCTGCGCAACACCCT
GGGCGTGCGAATCGGCGTGGTAGTCAACGACTTCGGTGCCATCAACATCGATGCCATGCTGGTTGCGGGCCAGGTCGACT
CGACCATGACCATGTCCAATGGATGCCTGTGCTGTACCGCCGATGATGACGAACTGGGCGGCATGCTGAGCGCTCTTGCC
GGCCGGGACATCGACGCGATCGTCATCGAGGCCAGCGGGCTGGCCGAGCCGCTGCCTTTGGTGCGCATGGTGCTCGCGGC
GACGGCCGAGGACCGGCGCATCGGTTACGGGGGACTGGTCACCGTCGTGGACACCGCTCAGTACGAGGACGTCGCCGTCC
GGCACCCGGAGATCGCTCAGCACCTGGACCTGGCGGATCTCGTGGTTCTCAACAAGATTGACCTGGCAGACGCCGGGGAC
CGTACCCATCTGCGCGCTGTCGTCAAGGAACGCAATCCACGGGCGTCGATCGTGGAGACCACCGGAGCCGACGTCGACCC
CCGGCTGTTGTTCGACAAGAAGGAGCGCCCCGAGCCTGTCGGTCAGCTCTCGCTCGAGGACCTCATTCGCGAGGATCACA
GCCATGAGCATCACGCGCACCATCACTACGAGACTGTCGAATTCGCGACGGAACAGCCGCTGCATCCACGGCGACTTATC
GAGTTTCTCGACAGTCAGCCGGCCGGCGTATACCGGATCAAGGGGCTGGTGCGACTGGGCGACAGGACGCTCGCGGTGCA
TACCGTGGGAGACCACATCAGCTTCGACAAAGTCGGGAGGGCATCGGATTTCTCGTCGGGGGCGAGTCTGGTGCTCATCG
GCACGCACCTGGACGGTGACACCATCACCGAGCGTCTGCGCACCCTCATCGACGACCCGCCCGATCCCGACCGCGAGCGA
TCGATGCTGGTCCTGGGAAAGTATTTGCGCTAA

Upstream 100 bases:

>100_bases
CGCAGACTATTTTCGTCAACGGCGGCATCATCTCGACCATCAACTAGTTGACGGCTTTACCTAGACTGGGCCGTGTGCGG
AGAAGTGTCGAGAACATAGC

Downstream 100 bases:

>100_bases
TCAGACGCCGCGTCTACTGTGGCTTCTCGTGCTGTACTTCTCCGGTCAACTCGTAGTAGCAACCCGCAGCGGGGTCTGAT
CCAGACCGACCCCTCGCTGT

Product: putative cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIPVTIVSGFLGAGKTTLLNNLLRNTLGVRIGVVVNDFGAINIDAMLVAGQVDSTMTMSNGCLCCTADDDELGGMLSALA
GRDIDAIVIEASGLAEPLPLVRMVLAATAEDRRIGYGGLVTVVDTAQYEDVAVRHPEIAQHLDLADLVVLNKIDLADAGD
RTHLRAVVKERNPRASIVETTGADVDPRLLFDKKERPEPVGQLSLEDLIREDHSHEHHAHHHYETVEFATEQPLHPRRLI
EFLDSQPAGVYRIKGLVRLGDRTLAVHTVGDHISFDKVGRASDFSSGASLVLIGTHLDGDTITERLRTLIDDPPDPDRER
SMLVLGKYLR

Sequences:

>Translated_330_residues
MIPVTIVSGFLGAGKTTLLNNLLRNTLGVRIGVVVNDFGAINIDAMLVAGQVDSTMTMSNGCLCCTADDDELGGMLSALA
GRDIDAIVIEASGLAEPLPLVRMVLAATAEDRRIGYGGLVTVVDTAQYEDVAVRHPEIAQHLDLADLVVLNKIDLADAGD
RTHLRAVVKERNPRASIVETTGADVDPRLLFDKKERPEPVGQLSLEDLIREDHSHEHHAHHHYETVEFATEQPLHPRRLI
EFLDSQPAGVYRIKGLVRLGDRTLAVHTVGDHISFDKVGRASDFSSGASLVLIGTHLDGDTITERLRTLIDDPPDPDRER
SMLVLGKYLR
>Mature_330_residues
MIPVTIVSGFLGAGKTTLLNNLLRNTLGVRIGVVVNDFGAINIDAMLVAGQVDSTMTMSNGCLCCTADDDELGGMLSALA
GRDIDAIVIEASGLAEPLPLVRMVLAATAEDRRIGYGGLVTVVDTAQYEDVAVRHPEIAQHLDLADLVVLNKIDLADAGD
RTHLRAVVKERNPRASIVETTGADVDPRLLFDKKERPEPVGQLSLEDLIREDHSHEHHAHHHYETVEFATEQPLHPRRLI
EFLDSQPAGVYRIKGLVRLGDRTLAVHTVGDHISFDKVGRASDFSSGASLVLIGTHLDGDTITERLRTLIDDPPDPDRER
SMLVLGKYLR

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=331, Percent_Identity=29.3051359516616, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI126722884, Length=331, Percent_Identity=28.7009063444109, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI148727351, Length=331, Percent_Identity=28.7009063444109, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI223941779, Length=322, Percent_Identity=27.639751552795, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI146231952, Length=331, Percent_Identity=28.7009063444109, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI223941776, Length=321, Percent_Identity=27.4143302180685, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI119120938, Length=316, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87082430, Length=197, Percent_Identity=32.994923857868, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324356, Length=218, Percent_Identity=28.4403669724771, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35942; Mature: 35942

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVTIVSGFLGAGKTTLLNNLLRNTLGVRIGVVVNDFGAINIDAMLVAGQVDSTMTMSN
CCCCEEEHHHHCCCHHHHHHHHHHHHHCEEEEEEEECCCCEEEEEEEEECCCCCEEEECC
GCLCCTADDDELGGMLSALAGRDIDAIVIEASGLAEPLPLVRMVLAATAEDRRIGYGGLV
CEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
TVVDTAQYEDVAVRHPEIAQHLDLADLVVLNKIDLADAGDRTHLRAVVKERNPRASIVET
EEEECCCCCCEECCCCHHHHHCCHHHHHEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEC
TGADVDPRLLFDKKERPEPVGQLSLEDLIREDHSHEHHAHHHYETVEFATEQPLHPRRLI
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
EFLDSQPAGVYRIKGLVRLGDRTLAVHTVGDHISFDKVGRASDFSSGASLVLIGTHLDGD
HHHCCCCCCEEEEEHEEEECCEEEEEEECCCCCCHHHCCCCCCCCCCCEEEEEEECCCCH
TITERLRTLIDDPPDPDRERSMLVLGKYLR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIPVTIVSGFLGAGKTTLLNNLLRNTLGVRIGVVVNDFGAINIDAMLVAGQVDSTMTMSN
CCCCEEEHHHHCCCHHHHHHHHHHHHHCEEEEEEEECCCCEEEEEEEEECCCCCEEEECC
GCLCCTADDDELGGMLSALAGRDIDAIVIEASGLAEPLPLVRMVLAATAEDRRIGYGGLV
CEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
TVVDTAQYEDVAVRHPEIAQHLDLADLVVLNKIDLADAGDRTHLRAVVKERNPRASIVET
EEEECCCCCCEECCCCHHHHHCCHHHHHEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEC
TGADVDPRLLFDKKERPEPVGQLSLEDLIREDHSHEHHAHHHYETVEFATEQPLHPRRLI
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
EFLDSQPAGVYRIKGLVRLGDRTLAVHTVGDHISFDKVGRASDFSSGASLVLIGTHLDGD
HHHCCCCCCEEEEEHEEEECCEEEEEEECCCCCCHHHCCCCCCCCCCCEEEEEEECCCCH
TITERLRTLIDDPPDPDRERSMLVLGKYLR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]