Click here to switch to the map view.

The map label for this gene is rnc [H]

Identifier: 169630337

GI number: 169630337

Start: 3295448

End: 3296224

Strand: Reverse

Name: rnc [H]

Synonym: MAB_3256c

Alternate gene names: 169630337

Gene position: 3296224-3295448 (Counterclockwise)

Preceding gene: 169630338

Following gene: 169630336

Centisome position: 65.05

GC content: 63.06

Gene sequence:

>777_bases
GTGAGTCGGACCCCCGAACATCGTCACGACGACCTGCGCGCGGCGATCGGTGTACAGCTCGGCGATGAGCTGCTTACGCT
TGCGCTCACGCATCGCAGCTATGCCTACGAGAACGGTGGCCTGCCCACCAACGAAAGGCTGGAGTTTCTCGGGGATGCCG
TTCTGGGTCTGACGATTACCGAGACGCTTTACCACAGCCACCCGGACCGTTCGGAAGGCGATTTGGCGAAGTTGCGTGCC
AGCATCGTCAACACCCAGGCGCTTGCCGGGGTCGCGCGCGGGCTGACCGGCGACGGATTGGGCGCCCATTTGCTGCTGGG
CAAGGGTGAGGAGAACACCGGTGGCCGTGACAAATCGAGCATTTTGGCCGATGGCATGGAGTCGATTCTGGGTGCGGTCT
ACCTGGAACACGGTCTGGAGACCGCGCGCGCTGTGGTGCTGACGTTGTTCGGCGAGCTGCTGGAGACCGCGCCCAAACTC
GGCGCCGGCCTGGACTGGAAGACCAGCTTGCAGGAGCTGACTGCGGAAAAGGGTTGGGGTGCGCCATCGTATGCGGTCAC
CTCAACCGGGCCCGACCATGACAAGGAGTTCACCGCCACGGTGATGGTCAACGACACCGCACATGGCGTGGGTGTGGGGA
GGTCAAAGAAAGAGGCCGAACAAAAGGCCGCCGCAGAGGCATGGAACAGCATCAGCGGCGATGAGCCTCTTGGGGGAAGA
GCAGAAGGCGGCGATGAGCCTCTTGAGGGAAGAGCAGAAGGCACGGTGAGTGCCTGA

Upstream 100 bases:

>100_bases
GCCCCGACTGCGGAATCGCCTTGGCGACAGCCGAACCGGGCCATCATCACGACAAGATCGATCCACGCTGGGCCAAACTT
GCCAACTTCGGTGATGACCA

Downstream 100 bases:

>100_bases
GCTTCCCGAGGTGGAGGTGGTTCGCCGCGGACTGCACCACCACCTTGTCGGCAAGACCATCGCATCGACGCTGGTGTACC
ACGAGCGTGCTGTGCGCAGA

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSRTPEHRHDDLRAAIGVQLGDELLTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITETLYHSHPDRSEGDLAKLRA
SIVNTQALAGVARGLTGDGLGAHLLLGKGEENTGGRDKSSILADGMESILGAVYLEHGLETARAVVLTLFGELLETAPKL
GAGLDWKTSLQELTAEKGWGAPSYAVTSTGPDHDKEFTATVMVNDTAHGVGVGRSKKEAEQKAAAEAWNSISGDEPLGGR
AEGGDEPLEGRAEGTVSA

Sequences:

>Translated_258_residues
MSRTPEHRHDDLRAAIGVQLGDELLTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITETLYHSHPDRSEGDLAKLRA
SIVNTQALAGVARGLTGDGLGAHLLLGKGEENTGGRDKSSILADGMESILGAVYLEHGLETARAVVLTLFGELLETAPKL
GAGLDWKTSLQELTAEKGWGAPSYAVTSTGPDHDKEFTATVMVNDTAHGVGVGRSKKEAEQKAAAEAWNSISGDEPLGGR
AEGGDEPLEGRAEGTVSA
>Mature_257_residues
SRTPEHRHDDLRAAIGVQLGDELLTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITETLYHSHPDRSEGDLAKLRAS
IVNTQALAGVARGLTGDGLGAHLLLGKGEENTGGRDKSSILADGMESILGAVYLEHGLETARAVVLTLFGELLETAPKLG
AGLDWKTSLQELTAEKGWGAPSYAVTSTGPDHDKEFTATVMVNDTAHGVGVGRSKKEAEQKAAAEAWNSISGDEPLGGRA
EGGDEPLEGRAEGTVSA

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=228, Percent_Identity=32.4561403508772, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI155030234, Length=228, Percent_Identity=32.4561403508772, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1788920, Length=199, Percent_Identity=37.6884422110553, Blast_Score=117, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17506883, Length=185, Percent_Identity=30.8108108108108, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193202651, Length=185, Percent_Identity=30.8108108108108, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137682, Length=228, Percent_Identity=31.140350877193, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 27076; Mature: 26945

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTPEHRHDDLRAAIGVQLGDELLTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ETLYHSHPDRSEGDLAKLRASIVNTQALAGVARGLTGDGLGAHLLLGKGEENTGGRDKSS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHH
ILADGMESILGAVYLEHGLETARAVVLTLFGELLETAPKLGAGLDWKTSLQELTAEKGWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
APSYAVTSTGPDHDKEFTATVMVNDTAHGVGVGRSKKEAEQKAAAEAWNSISGDEPLGGR
CCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
AEGGDEPLEGRAEGTVSA
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRTPEHRHDDLRAAIGVQLGDELLTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ETLYHSHPDRSEGDLAKLRASIVNTQALAGVARGLTGDGLGAHLLLGKGEENTGGRDKSS
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHH
ILADGMESILGAVYLEHGLETARAVVLTLFGELLETAPKLGAGLDWKTSLQELTAEKGWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
APSYAVTSTGPDHDKEFTATVMVNDTAHGVGVGRSKKEAEQKAAAEAWNSISGDEPLGGR
CCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
AEGGDEPLEGRAEGTVSA
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]