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The map label for this gene is mpt53 [H]

Identifier: 169630324

GI number: 169630324

Start: 3279640

End: 3280176

Strand: Direct

Name: mpt53 [H]

Synonym: MAB_3243

Alternate gene names: 169630324

Gene position: 3279640-3280176 (Clockwise)

Preceding gene: 169630323

Following gene: 169630325

Centisome position: 64.72

GC content: 62.38

Gene sequence:

>537_bases
ATGAATATCCAATTCGGGGGACGTAAAAAGTTTCGGGCCCAGCAGGTTCGAGGGCTGACGCGCACCGTTGCGGTGGTCGT
CGCTGTGTTGTTGGTATCCGCTGGTCTGGTGCGGGCCCCCAGTGCACGCGCCGATGGCCTACTCGATTTCACCGGAACCA
CCGTGTCGGGTGCGCCGTTCAACGGCGCCAGCCTCAAGGGCAAACCCGTAGTGCTGTGGTTCTGGGCGGCATACTGCCCG
TTCTGCAATGGCGAGGGGCCGCATGTGAGTGCGGTGTCGGCGGCCAATCCCCGCGTCACGTTCGTCGGCATCTCCGGCCG
CGGATCGGTCGGGGAAATGGAGGCGTTCATCTCGCGCTACAACCTCCATTTCACCAACCTCAATGACGCCGACGGCTCGC
TGTGGCGGCAGTTCGGGGTGCCCTGGCAACCCGCGTACCTGTTCATCAACTCCAACGGAACCTCGGACTTTGTGAACAAC
CCCACATCGTCGATGTCCGAACAGGAGCTCAGTGACCGGGTGAAGGCACTGACCTGA

Upstream 100 bases:

>100_bases
CGTCCCCGTTCAAGCCCCCGCTAAACACGGGAAACCCGTCATACACTGCGGGAGTCACACCGTGTTGGCTGTGTGTTTTG
GGTCCCAGGAGGTTCTTGGC

Downstream 100 bases:

>100_bases
CGTCTCTGGCCTTCGCAGCGGGGCTGATCGCCGCGCTCAACCCGTGCGGCTTCGCCTTACTGCCGGTCTACCTCGCGCTC
GTGGTGCGTGGGCCCGGTGC

Product: soluble secreted antigen MPT53 precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MNIQFGGRKKFRAQQVRGLTRTVAVVVAVLLVSAGLVRAPSARADGLLDFTGTTVSGAPFNGASLKGKPVVLWFWAAYCP
FCNGEGPHVSAVSAANPRVTFVGISGRGSVGEMEAFISRYNLHFTNLNDADGSLWRQFGVPWQPAYLFINSNGTSDFVNN
PTSSMSEQELSDRVKALT

Sequences:

>Translated_178_residues
MNIQFGGRKKFRAQQVRGLTRTVAVVVAVLLVSAGLVRAPSARADGLLDFTGTTVSGAPFNGASLKGKPVVLWFWAAYCP
FCNGEGPHVSAVSAANPRVTFVGISGRGSVGEMEAFISRYNLHFTNLNDADGSLWRQFGVPWQPAYLFINSNGTSDFVNN
PTSSMSEQELSDRVKALT
>Mature_178_residues
MNIQFGGRKKFRAQQVRGLTRTVAVVVAVLLVSAGLVRAPSARADGLLDFTGTTVSGAPFNGASLKGKPVVLWFWAAYCP
FCNGEGPHVSAVSAANPRVTFVGISGRGSVGEMEAFISRYNLHFTNLNDADGSLWRQFGVPWQPAYLFINSNGTSDFVNN
PTSSMSEQELSDRVKALT

Specific function: Disulfide oxidoreductase that catalyzes the oxidation of reduced, unfolded secreted proteins to form disulfide bonds. Despite a weak homology to thioredoxin this cannot serve as a substrate for thioredoxin reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19117; Mature: 19117

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQFGGRKKFRAQQVRGLTRTVAVVVAVLLVSAGLVRAPSARADGLLDFTGTTVSGAPF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEECCCCC
NGASLKGKPVVLWFWAAYCPFCNGEGPHVSAVSAANPRVTFVGISGRGSVGEMEAFISRY
CCCCCCCCCEEEEEEHHHCCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHH
NLHFTNLNDADGSLWRQFGVPWQPAYLFINSNGTSDFVNNPTSSMSEQELSDRVKALT
CEEECCCCCCCHHHHHHHCCCCCCEEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIQFGGRKKFRAQQVRGLTRTVAVVVAVLLVSAGLVRAPSARADGLLDFTGTTVSGAPF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEECCCCC
NGASLKGKPVVLWFWAAYCPFCNGEGPHVSAVSAANPRVTFVGISGRGSVGEMEAFISRY
CCCCCCCCCEEEEEEHHHCCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHH
NLHFTNLNDADGSLWRQFGVPWQPAYLFINSNGTSDFVNNPTSSMSEQELSDRVKALT
CEEECCCCCCCHHHHHHHCCCCCCEEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]