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The map label for this gene is pnuC [H]

Identifier: 169630272

GI number: 169630272

Start: 3235522

End: 3236100

Strand: Reverse

Name: pnuC [H]

Synonym: MAB_3190c

Alternate gene names: 169630272

Gene position: 3236100-3235522 (Counterclockwise)

Preceding gene: 169630274

Following gene: 169630271

Centisome position: 63.86

GC content: 60.45

Gene sequence:

>579_bases
GTGGACTGGACCGAGCTAATTGGCAGCCTGTCCGGTGTGCTGTTCGTCATTCTGGCGGTACGGCAAAATATTTGGACCTT
CCCGGTGGCGATCGTCAGCTCGCTGTTCTACATGGTGGTCTTCAGTCGGCAGACCCTGTACGCCGACGCGGCCCTGCAGA
TCATGTTTATCGCTCTGGCCGCGCAGGGTTGGCATCTATGGCTGCGGGGAAGTCAGGACCGGCACGGGGTGACAGTCACG
CGTACACCGCAACGGGCGTGGCTCCCACTGGTCTCGTGCCTCGTCGCCCTGGTCGCGGGCCTCTACGCGTTTCTGGTTAC
CTTCACCGATTCAAATGCCCCGCAGCTTGATTCGGCCATCACGGGGTTCAGCGTGGTTTCCCAGCTCATGATGAACCGTA
AGTGGATCGAAAACTGGATCCTGTGGATCGTCACCGATACGTTCTCCGTCGGCGTCTATCTGTACAAGGGGCTGAACCTC
ACGGCGGGTTTCTACGCGTTCCTCAGCGTCATGGCCGCGGTGGGGCTGTGGAGTTGGCGGAAAGAATTGCACGCGGTGGC
GACCACCGAATCGGCCTGA

Upstream 100 bases:

>100_bases
GTTCGCTGTCGTTGATCAGCCCGGCCAGCCACGAGAAGCTCCGCTGCTGGTCCGCCGTCGTCATGGCGCGAGCTTACTGC
TGCTCGGCTAATCTGGTGCC

Downstream 100 bases:

>100_bases
ATAACCTTTCCCCTTTCAACTTATAACGCACAGGGGGGCTTGCGGCAAGACCCGGGTGATACCGCACAATCACTGAGCTC
AAATGTCAGATGCCATGGAC

Product: putative nicotinamide mononucleotide transporter

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MDWTELIGSLSGVLFVILAVRQNIWTFPVAIVSSLFYMVVFSRQTLYADAALQIMFIALAAQGWHLWLRGSQDRHGVTVT
RTPQRAWLPLVSCLVALVAGLYAFLVTFTDSNAPQLDSAITGFSVVSQLMMNRKWIENWILWIVTDTFSVGVYLYKGLNL
TAGFYAFLSVMAAVGLWSWRKELHAVATTESA

Sequences:

>Translated_192_residues
MDWTELIGSLSGVLFVILAVRQNIWTFPVAIVSSLFYMVVFSRQTLYADAALQIMFIALAAQGWHLWLRGSQDRHGVTVT
RTPQRAWLPLVSCLVALVAGLYAFLVTFTDSNAPQLDSAITGFSVVSQLMMNRKWIENWILWIVTDTFSVGVYLYKGLNL
TAGFYAFLSVMAAVGLWSWRKELHAVATTESA
>Mature_192_residues
MDWTELIGSLSGVLFVILAVRQNIWTFPVAIVSSLFYMVVFSRQTLYADAALQIMFIALAAQGWHLWLRGSQDRHGVTVT
RTPQRAWLPLVSCLVALVAGLYAFLVTFTDSNAPQLDSAITGFSVVSQLMMNRKWIENWILWIVTDTFSVGVYLYKGLNL
TAGFYAFLSVMAAVGLWSWRKELHAVATTESA

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=204, Percent_Identity=24.0196078431373, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 21489; Mature: 21489

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWTELIGSLSGVLFVILAVRQNIWTFPVAIVSSLFYMVVFSRQTLYADAALQIMFIALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGWHLWLRGSQDRHGVTVTRTPQRAWLPLVSCLVALVAGLYAFLVTFTDSNAPQLDSAI
HCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TGFSVVSQLMMNRKWIENWILWIVTDTFSVGVYLYKGLNLTAGFYAFLSVMAAVGLWSWR
HHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KELHAVATTESA
HHHHHHHCCCCC
>Mature Secondary Structure
MDWTELIGSLSGVLFVILAVRQNIWTFPVAIVSSLFYMVVFSRQTLYADAALQIMFIALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGWHLWLRGSQDRHGVTVTRTPQRAWLPLVSCLVALVAGLYAFLVTFTDSNAPQLDSAI
HCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TGFSVVSQLMMNRKWIENWILWIVTDTFSVGVYLYKGLNLTAGFYAFLSVMAAVGLWSWR
HHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
KELHAVATTESA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]