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The map label for this gene is cobO [H]

Identifier: 169630238

GI number: 169630238

Start: 3202688

End: 3203302

Strand: Reverse

Name: cobO [H]

Synonym: MAB_3156c

Alternate gene names: 169630238

Gene position: 3203302-3202688 (Counterclockwise)

Preceding gene: 169630239

Following gene: 169630237

Centisome position: 63.22

GC content: 65.37

Gene sequence:

>615_bases
ATGCCACAGGGGCAGCCATTGGTGGTGCCGCAGGACGGCCTGACCACCAAGGCACGTCGCAACGCGCCGATTCTGGCAGT
GCATACCGGCGCCGGAAAAGGCAAGTCGACGGCCGCCTTTGGCATGGCTCTGCGTGCCTGGCACCACGGAGCCGATGTCG
CGGTGTTCCAATTCGTCAAGAGTGCCAAATGGCGTGTGGGCGAGGAGTCGGTCTTCGGTGAACTCGCCAAGCTGCACGAT
GAGCACGGAATCGGCGGCTCGGTGCAGTGGCACAAGATGGGGTCGGGGTGGTCCTGGTCACGCAAGGCGGGAACCGAGAC
GGACCACGCCGCGGACGCGGCAGCTGGGTGGGCCGAAATCGCACGGCGGCTGGCAGCGCAGGAGCACGGCTTCTACGTGC
TGGATGAGTTCACCTATCCGCTCAAGTGGGGATGGGTCGACCCGGACGAAGTTGTCGAGGTGCTGCGCTCCCGGCCTGGC
ATGCAACACGTGGTCATCACCGGGCGTGACGCACCGCAGCAGCTGCTGGACGCGGCCGATCTGGTGACCGAGATGACCAA
GGTCAAGCATCCGATGGACCAGGGTCGCAAGGGCCAGCGCGGCATTGAATGGTGA

Upstream 100 bases:

>100_bases
GACGCGCCGGTGATCCAGCTTGACCATCTGAACGCTGACCGGCTCGCCGGAGTGGTGCGCGGCGCGACTGCCGCTGCGTG
AGCTAGCAGAGGAGGTTCGG

Downstream 100 bases:

>100_bases
TGGCGTGGTGGCCCATTGAGCACGGTATTCGCTAGCGTCCCCGCCGTGGTGATTGCCGCGCCGGCTTCCGGCAGCGGAAA
GACCACGGTGGCAACGGGTT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MPQGQPLVVPQDGLTTKARRNAPILAVHTGAGKGKSTAAFGMALRAWHHGADVAVFQFVKSAKWRVGEESVFGELAKLHD
EHGIGGSVQWHKMGSGWSWSRKAGTETDHAADAAAGWAEIARRLAAQEHGFYVLDEFTYPLKWGWVDPDEVVEVLRSRPG
MQHVVITGRDAPQQLLDAADLVTEMTKVKHPMDQGRKGQRGIEW

Sequences:

>Translated_204_residues
MPQGQPLVVPQDGLTTKARRNAPILAVHTGAGKGKSTAAFGMALRAWHHGADVAVFQFVKSAKWRVGEESVFGELAKLHD
EHGIGGSVQWHKMGSGWSWSRKAGTETDHAADAAAGWAEIARRLAAQEHGFYVLDEFTYPLKWGWVDPDEVVEVLRSRPG
MQHVVITGRDAPQQLLDAADLVTEMTKVKHPMDQGRKGQRGIEW
>Mature_203_residues
PQGQPLVVPQDGLTTKARRNAPILAVHTGAGKGKSTAAFGMALRAWHHGADVAVFQFVKSAKWRVGEESVFGELAKLHDE
HGIGGSVQWHKMGSGWSWSRKAGTETDHAADAAAGWAEIARRLAAQEHGFYVLDEFTYPLKWGWVDPDEVVEVLRSRPGM
QHVVITGRDAPQQLLDAADLVTEMTKVKHPMDQGRKGQRGIEW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=193, Percent_Identity=37.8238341968912, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22421; Mature: 22289

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGQPLVVPQDGLTTKARRNAPILAVHTGAGKGKSTAAFGMALRAWHHGADVAVFQFVK
CCCCCEEEECCCCCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
SAKWRVGEESVFGELAKLHDEHGIGGSVQWHKMGSGWSWSRKAGTETDHAADAAAGWAEI
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
ARRLAAQEHGFYVLDEFTYPLKWGWVDPDEVVEVLRSRPGMQHVVITGRDAPQQLLDAAD
HHHHHHHHCCCEEEECCCCCEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
LVTEMTKVKHPMDQGRKGQRGIEW
HHHHHHHHHCCHHCCCCCCCCCCC
>Mature Secondary Structure 
PQGQPLVVPQDGLTTKARRNAPILAVHTGAGKGKSTAAFGMALRAWHHGADVAVFQFVK
CCCCEEEECCCCCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
SAKWRVGEESVFGELAKLHDEHGIGGSVQWHKMGSGWSWSRKAGTETDHAADAAAGWAEI
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
ARRLAAQEHGFYVLDEFTYPLKWGWVDPDEVVEVLRSRPGMQHVVITGRDAPQQLLDAAD
HHHHHHHHCCCEEEECCCCCEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHH
LVTEMTKVKHPMDQGRKGQRGIEW
HHHHHHHHHCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]