| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is paaF [H]
Identifier: 169630206
GI number: 169630206
Start: 3164897
End: 3165655
Strand: Direct
Name: paaF [H]
Synonym: MAB_3124
Alternate gene names: 169630206
Gene position: 3164897-3165655 (Clockwise)
Preceding gene: 169630205
Following gene: 169630209
Centisome position: 62.46
GC content: 67.85
Gene sequence:
>759_bases ATGACCGAACCAATTTTGTTGACCCACACCGAAGACCGCATCTGCACCATCACCCTGAACCGGCCGCAAGCACGTAACGC CTTGAGCACCGCCCTGGGCGAGGAGATCGTCAAGGCCGTCACCGCGGCCGACGCCGACGAGAACGTCGACGTGATGATCC TGACCGCGGCCGACCCGGTCTTCTGCGCGGGCGTGGACCTCAAGGAGCTGGGCAGTGGCGATCGTGCCGAGTCCCTGGAC CCGTGGTGGCCCGAACTGAGCAAGCCGGTCATCGGCGCCATCAACGGCGCTGCGGTGACCGGCGGTCTGGAGTTGGCACT GGCCTGCGACATTCTCATCGCCTCGGAGAAGGCACGATTCGCCGACACCCATGCGCGCGTTGGCATCTTGCCGACCTGGG GGCTGACCACCCTGCTGCCGCTCTCGGTGGGGCGGGGCCTGGCCCGGCGGATGAGCCTGACCGGCGACTACCTCTCCGCC GAGGATGCGCTGCGGGCAGGCCTGGTGACCGAGGTGGTCGCGCACAACGAGCTCCTCCCCGCCGCCAAGCGTCTCGCCGC GACCATTGCCGGCAACAACCAGCCCGCGGTCCGCGAACTGCTGGCGTCCTACCGCCGTATAGAGTCCGAGCTCGTCGGCA ACGGCCTGCAGGTGGCTCTCGACGATGCTCACCGGTGGATCGATCAGAACTCGATCGCCGAGGGCGTAGAGGCTCGGCGC ACCGCGATCATGGAGCGCGGACGCAGCCAGAACGCCTAG
Upstream 100 bases:
>100_bases ACCCGGCCCATCTGTATTACAAACGCGCCGTGAGTAACTCGGCCCTCTTCGGGGGGCGCGCCGTCCACGCCGAACGTATT GCCAAGGAGGTAATCGACGC
Downstream 100 bases:
>100_bases GCGCGATCGGTTCGGTACAACGCGATCCGGCGATCGGGCCGAATATCGAACTCACCCAGGAACGTCCAGCCAATCCGGTC GAGCGCCTTGCGCATCGGCG
Product: enoyl-CoA hydratase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 252; Mature: 251
Protein sequence:
>252_residues MTEPILLTHTEDRICTITLNRPQARNALSTALGEEIVKAVTAADADENVDVMILTAADPVFCAGVDLKELGSGDRAESLD PWWPELSKPVIGAINGAAVTGGLELALACDILIASEKARFADTHARVGILPTWGLTTLLPLSVGRGLARRMSLTGDYLSA EDALRAGLVTEVVAHNELLPAAKRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHRWIDQNSIAEGVEARR TAIMERGRSQNA
Sequences:
>Translated_252_residues MTEPILLTHTEDRICTITLNRPQARNALSTALGEEIVKAVTAADADENVDVMILTAADPVFCAGVDLKELGSGDRAESLD PWWPELSKPVIGAINGAAVTGGLELALACDILIASEKARFADTHARVGILPTWGLTTLLPLSVGRGLARRMSLTGDYLSA EDALRAGLVTEVVAHNELLPAAKRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHRWIDQNSIAEGVEARR TAIMERGRSQNA >Mature_251_residues TEPILLTHTEDRICTITLNRPQARNALSTALGEEIVKAVTAADADENVDVMILTAADPVFCAGVDLKELGSGDRAESLDP WWPELSKPVIGAINGAAVTGGLELALACDILIASEKARFADTHARVGILPTWGLTTLLPLSVGRGLARRMSLTGDYLSAE DALRAGLVTEVVAHNELLPAAKRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHRWIDQNSIAEGVEARRT AIMERGRSQNA
Specific function: Could possibly oxidize fatty acids using specific components [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=188, Percent_Identity=40.4255319148936, Blast_Score=127, Evalue=6e-30, Organism=Homo sapiens, GI31542718, Length=213, Percent_Identity=34.7417840375587, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI70995211, Length=199, Percent_Identity=26.6331658291457, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI25453481, Length=182, Percent_Identity=29.6703296703297, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI51538573, Length=182, Percent_Identity=29.6703296703297, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI4757966, Length=182, Percent_Identity=29.6703296703297, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI51538581, Length=182, Percent_Identity=29.6703296703297, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI4502327, Length=197, Percent_Identity=34.5177664974619, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI37594469, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI37594471, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI4757968, Length=182, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI49355787, Length=182, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI116235487, Length=198, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI45643119, Length=181, Percent_Identity=28.7292817679558, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI260275230, Length=181, Percent_Identity=28.7292817679558, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI260274832, Length=181, Percent_Identity=28.7292817679558, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI221307494, Length=161, Percent_Identity=29.8136645962733, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI221136756, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI221136753, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI68989263, Length=175, Percent_Identity=29.7142857142857, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787659, Length=192, Percent_Identity=39.5833333333333, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI221142681, Length=238, Percent_Identity=34.0336134453782, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1787660, Length=206, Percent_Identity=33.0097087378641, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1788597, Length=214, Percent_Identity=32.2429906542056, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1788682, Length=214, Percent_Identity=32.7102803738318, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1790281, Length=191, Percent_Identity=27.7486910994764, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17554946, Length=187, Percent_Identity=34.2245989304813, Blast_Score=117, Evalue=8e-27, Organism=Caenorhabditis elegans, GI25145438, Length=238, Percent_Identity=33.6134453781513, Blast_Score=116, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17540714, Length=180, Percent_Identity=33.8888888888889, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560910, Length=201, Percent_Identity=29.8507462686567, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17534483, Length=200, Percent_Identity=29.5, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17535521, Length=190, Percent_Identity=30, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI25144160, Length=221, Percent_Identity=28.9592760180996, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI25144157, Length=221, Percent_Identity=28.9592760180996, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17540306, Length=214, Percent_Identity=28.9719626168224, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17549921, Length=190, Percent_Identity=28.4210526315789, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6320241, Length=213, Percent_Identity=27.6995305164319, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI20129971, Length=180, Percent_Identity=36.6666666666667, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI24653477, Length=180, Percent_Identity=36.6666666666667, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI24650670, Length=195, Percent_Identity=33.8461538461538, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24653139, Length=188, Percent_Identity=35.1063829787234, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI21357171, Length=203, Percent_Identity=30.0492610837438, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI24654903, Length=187, Percent_Identity=24.0641711229947, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24583165, Length=251, Percent_Identity=22.7091633466135, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI19922422, Length=185, Percent_Identity=26.4864864864865, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI19921018, Length=178, Percent_Identity=27.5280898876405, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.17 [H]
Molecular weight: Translated: 26860; Mature: 26729
Theoretical pI: Translated: 4.69; Mature: 4.69
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTEPILLTHTEDRICTITLNRPQARNALSTALGEEIVKAVTAADADENVDVMILTAADPV CCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCE FCAGVDLKELGSGDRAESLDPWWPELSKPVIGAINGAAVTGGLELALACDILIASEKARF EECCCCHHHHCCCCCCCCCCCCCHHHCCCCEECCCCCEEECCHHHHHHHHHHEECCCHHH ADTHARVGILPTWGLTTLLPLSVGRGLARRMSLTGDYLSAEDALRAGLVTEVVAHNELLP HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH AAKRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHRWIDQNSIAEGVEARR HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCHHHHHHHHHHHH TAIMERGRSQNA HHHHHCCCCCCC >Mature Secondary Structure TEPILLTHTEDRICTITLNRPQARNALSTALGEEIVKAVTAADADENVDVMILTAADPV CCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCE FCAGVDLKELGSGDRAESLDPWWPELSKPVIGAINGAAVTGGLELALACDILIASEKARF EECCCCHHHHCCCCCCCCCCCCCHHHCCCCEECCCCCEEECCHHHHHHHHHHEECCCHHH ADTHARVGILPTWGLTTLLPLSVGRGLARRMSLTGDYLSAEDALRAGLVTEVVAHNELLP HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH AAKRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHRWIDQNSIAEGVEARR HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCHHHHHHHHHHHH TAIMERGRSQNA HHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9748275; 9097039; 9278503; 10766858 [H]