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The map label for this gene is pqqL [C]

Identifier: 169630187

GI number: 169630187

Start: 3148518

End: 3149753

Strand: Reverse

Name: pqqL [C]

Synonym: MAB_3105c

Alternate gene names: 169630187

Gene position: 3149753-3148518 (Counterclockwise)

Preceding gene: 169630188

Following gene: 169630186

Centisome position: 62.16

GC content: 65.7

Gene sequence:

>1236_bases
ATGCCCTCGGTGCGCTCGGCGTCCGTCGGCGTGTGGGTCGACGTGGGGTCGCGCGACGAGGGGCGCAGTGTCGCCGGTGC
GGCGCACTTCCTCGAGCACCTGCTGTTCAAATCCACGCCCACCCGGTCGGCGGCCGATATCGCCCAGTCGATCGACGCCG
TCGGGGGCGAGCTCAACGCCTTCACCGCACGCGAGCAGACCTGTTATTACGCTCATGTGCTGGACTCCGATCTGGAGTTG
GCCATAGACCTGGTGGCCGATGTGGTGTTGCGCGGGCGATGCGCCAGCGACGACGTCGAGGTCGAGCGTGATGTGGTGCT
CGAAGAAATCGCGATGCGTGACGACGATCCCGAGGATCTGCTGGGGGAGGCCTTCCTGGGTGCGCTGTTCGGTGATCATC
CGATCGGCCGCAGCGTGCTGGGCAGCTCCGAATCGATTTCGGCGATGACGCGGGCGCAACTGCATTCATTCCATGTGCGG
CGGTACCGCCCCGAACGTATGGTGCTGGCGGTCGCCGGAAACATCGAACACGATCGTGTAGTCCGGTTGGCGCGCAAGTA
TTTCAAGTCGCATCTGGACTCATCGGTGCGGACGGTGGCGCCCCGCAAGGGCAGTGGCCGGGTCGCGGCCAAGCCGGGGC
TCGAGTTGGTGTCACGCGACGGTGAGCAGGTGCACCTGTCGCTTGGGGTGCGCACTCCCGGGCGCGGCTGGCAGCATCGC
TGGGCGCTGTCGGTACTCAACAGCGCACTCGGCGGTGGCCTCAGTTCTCGCCTGTTTCAAGAGATTCGCGAGCAGCGAGG
GCTGGTGTACGCGGTGTATTCGACGGTGGATACCTTCTCGGACACCGGCGCCTTGTCGGTATACGCGGGCTGCTCCCCGG
AGCGATTCGACGAGGTGACGAAGGTGACCTCGCAGGTGTTGGGATCGGTCGTCGAGGACGGATTCACCCCGGCGGAAATC
GATCGTGCCAAGGGGGCGCTCTCCGGTGGACTCGTTCTGGGGCTTGAAGATTCGGCATCGCGGATGAATCGGTTGGGCCG
CAGCGAGCTGAACAACGGCAAGCACCGCACCATTTCCGCGACCCTGGACAGGATCGACGCGGTGACGGCCGACGAGGTCA
ACGCCATCGCCCGCCAGTTGCTCGGCGGCCCCGCCGGGGCGGCGGTGGTGGGACCGTACCGATCCAAGCGGACGTTGCCG
CGCACATTGCGGACGATGATTGAATCCACAAGCTAG

Upstream 100 bases:

>100_bases
CAGTAAGGTCCCGAGCGCAGGGTCCGAGTCTCTTCGCGCAAGCGGCTCATCGGTACGCCGCACGGTTCTTCCAGGTGGGC
TCCGAGTAGTCACCGAGGCC

Downstream 100 bases:

>100_bases
TTCACGGCCGGGAAGATATCCTCTAGCTGATGGTCGCCCATGCGATTCAGCGCGTTAGGGAACTAACGGCTGGCACATAC
ACAGGGATCGTGGCCGCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MPSVRSASVGVWVDVGSRDEGRSVAGAAHFLEHLLFKSTPTRSAADIAQSIDAVGGELNAFTAREQTCYYAHVLDSDLEL
AIDLVADVVLRGRCASDDVEVERDVVLEEIAMRDDDPEDLLGEAFLGALFGDHPIGRSVLGSSESISAMTRAQLHSFHVR
RYRPERMVLAVAGNIEHDRVVRLARKYFKSHLDSSVRTVAPRKGSGRVAAKPGLELVSRDGEQVHLSLGVRTPGRGWQHR
WALSVLNSALGGGLSSRLFQEIREQRGLVYAVYSTVDTFSDTGALSVYAGCSPERFDEVTKVTSQVLGSVVEDGFTPAEI
DRAKGALSGGLVLGLEDSASRMNRLGRSELNNGKHRTISATLDRIDAVTADEVNAIARQLLGGPAGAAVVGPYRSKRTLP
RTLRTMIESTS

Sequences:

>Translated_411_residues
MPSVRSASVGVWVDVGSRDEGRSVAGAAHFLEHLLFKSTPTRSAADIAQSIDAVGGELNAFTAREQTCYYAHVLDSDLEL
AIDLVADVVLRGRCASDDVEVERDVVLEEIAMRDDDPEDLLGEAFLGALFGDHPIGRSVLGSSESISAMTRAQLHSFHVR
RYRPERMVLAVAGNIEHDRVVRLARKYFKSHLDSSVRTVAPRKGSGRVAAKPGLELVSRDGEQVHLSLGVRTPGRGWQHR
WALSVLNSALGGGLSSRLFQEIREQRGLVYAVYSTVDTFSDTGALSVYAGCSPERFDEVTKVTSQVLGSVVEDGFTPAEI
DRAKGALSGGLVLGLEDSASRMNRLGRSELNNGKHRTISATLDRIDAVTADEVNAIARQLLGGPAGAAVVGPYRSKRTLP
RTLRTMIESTS
>Mature_410_residues
PSVRSASVGVWVDVGSRDEGRSVAGAAHFLEHLLFKSTPTRSAADIAQSIDAVGGELNAFTAREQTCYYAHVLDSDLELA
IDLVADVVLRGRCASDDVEVERDVVLEEIAMRDDDPEDLLGEAFLGALFGDHPIGRSVLGSSESISAMTRAQLHSFHVRR
YRPERMVLAVAGNIEHDRVVRLARKYFKSHLDSSVRTVAPRKGSGRVAAKPGLELVSRDGEQVHLSLGVRTPGRGWQHRW
ALSVLNSALGGGLSSRLFQEIREQRGLVYAVYSTVDTFSDTGALSVYAGCSPERFDEVTKVTSQVLGSVVEDGFTPAEID
RAKGALSGGLVLGLEDSASRMNRLGRSELNNGKHRTISATLDRIDAVTADEVNAIARQLLGGPAGAAVVGPYRSKRTLPR
TLRTMIESTS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=407, Percent_Identity=29.7297297297297, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI46593007, Length=391, Percent_Identity=29.6675191815857, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI24308013, Length=422, Percent_Identity=27.7251184834123, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI50592988, Length=409, Percent_Identity=23.4718826405868, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1787770, Length=188, Percent_Identity=24.468085106383, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=406, Percent_Identity=30.0492610837438, Blast_Score=178, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17553678, Length=405, Percent_Identity=29.8765432098765, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17510601, Length=410, Percent_Identity=22.4390243902439, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=409, Percent_Identity=28.8508557457213, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6321813, Length=402, Percent_Identity=22.8855721393035, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21357875, Length=401, Percent_Identity=28.6783042394015, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24646943, Length=401, Percent_Identity=28.6783042394015, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI19921772, Length=417, Percent_Identity=25.8992805755396, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 44347; Mature: 44216

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVRSASVGVWVDVGSRDEGRSVAGAAHFLEHLLFKSTPTRSAADIAQSIDAVGGELNA
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
FTAREQTCYYAHVLDSDLELAIDLVADVVLRGRCASDDVEVERDVVLEEIAMRDDDPEDL
EECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH
LGEAFLGALFGDHPIGRSVLGSSESISAMTRAQLHSFHVRRYRPERMVLAVAGNIEHDRV
HHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
VRLARKYFKSHLDSSVRTVAPRKGSGRVAAKPGLELVSRDGEQVHLSLGVRTPGRGWQHR
HHHHHHHHHHHHCCHHHCCCCCCCCCCEECCCCHHHHHCCCCEEEEEEECCCCCCCCHHH
WALSVLNSALGGGLSSRLFQEIREQRGLVYAVYSTVDTFSDTGALSVYAGCSPERFDEVT
HHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCCEEEEECCCHHHHHHHH
KVTSQVLGSVVEDGFTPAEIDRAKGALSGGLVLGLEDSASRMNRLGRSELNNGKHRTISA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEHHH
TLDRIDAVTADEVNAIARQLLGGPAGAAVVGPYRSKRTLPRTLRTMIESTS
HHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
PSVRSASVGVWVDVGSRDEGRSVAGAAHFLEHLLFKSTPTRSAADIAQSIDAVGGELNA
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
FTAREQTCYYAHVLDSDLELAIDLVADVVLRGRCASDDVEVERDVVLEEIAMRDDDPEDL
EECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH
LGEAFLGALFGDHPIGRSVLGSSESISAMTRAQLHSFHVRRYRPERMVLAVAGNIEHDRV
HHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
VRLARKYFKSHLDSSVRTVAPRKGSGRVAAKPGLELVSRDGEQVHLSLGVRTPGRGWQHR
HHHHHHHHHHHHCCHHHCCCCCCCCCCEECCCCHHHHHCCCCEEEEEEECCCCCCCCHHH
WALSVLNSALGGGLSSRLFQEIREQRGLVYAVYSTVDTFSDTGALSVYAGCSPERFDEVT
HHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCCEEEEECCCHHHHHHHH
KVTSQVLGSVVEDGFTPAEIDRAKGALSGGLVLGLEDSASRMNRLGRSELNNGKHRTISA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEHHH
TLDRIDAVTADEVNAIARQLLGGPAGAAVVGPYRSKRTLPRTLRTMIESTS
HHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]