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The map label for this gene is cmlR [H]

Identifier: 169630066

GI number: 169630066

Start: 3042961

End: 3044139

Strand: Reverse

Name: cmlR [H]

Synonym: MAB_2983c

Alternate gene names: 169630066

Gene position: 3044139-3042961 (Counterclockwise)

Preceding gene: 169630067

Following gene: 169630065

Centisome position: 60.08

GC content: 64.8

Gene sequence:

>1179_bases
GTGACACTGCCTATCTACGCGCTCACCTTGGCCATATTCGCCCAGGGCTGTTCGGAATTCATGTTCGCCGGGCTCATCAC
CGAGGTGGGTGACGACTTTGGTGTCTCGCTGGCTGCGGCGGGAACGCTGACGTCAGCGTTTGCCGTTGGCATCATCGTCG
GTGCTCCACTGATGGCTCTTATCAGTGGTCGTTGGCCCCGGCGCCGGGCGCTCGTGTTGTTCTTGTCGGTCTTTATCGCA
GCGCACATCGTGGGCGCGACGGCCGCGAGCTTTCCGTTGCTGTTGATCGTTCGTGTGGTTTCGGCGGTCGCTAACGCCGG
ATTCCTGGCAGTGGCGCTGACGACAGCGATGTCCATTACGGGTCCACGCGCGAAGGGGCGCACCACAGCGTTGCTGCTCA
GTGGCATAACAATCGCCTGTGTCGCAGGAGTACCCGGCGGCGCGGCGCTCGGCTACTTCTGGGGATGGCGTGCGGCGCTG
TGGGCGGTGGTGCTGGTATCGGTGCCGGCGCTCGCGGCGATCATGTACGCACTACCAGTCGGACGGCCGGTGACCGGCTT
ACCGGACGGAATTGGTGAATTGCGGACGCTTCGGAACCGACGGCTGCAGATAACGCTGGCCGCGGGAGTTCTGTGCAACG
CAGCAACCTTTTGTGCCTTTACCTATCTGGCTCCCGTCTCGGTGCAGGTCACCTCGTTGAGTCCGGCGTGGACTCCGGCG
CTCCTGGCACTCTTTGGGTGTGGCTCGTTTGTCGGCGTCCACGCCACGGGCAGACTCGCCGACTCACACGCCAACCTGGT
AGCCGGTGGGGGCGGAGTGTTGCTGCTGGCGGGCTGGATCGCGTTCGCGGGCACGGCGGCTCACGACTGGCTTTTCGTCA
CGCTCGTGTTCGCACTGGGCGCGTTGTCGTTCGGCGTCGGCTCGACCCTGTTTTCGCAGGGGCTGTACGCCGCGAGTGAT
GCGCCCATGCTGGGCAGCTCGCTCACCACCGCTGCCTTCAACGTCGGTACCGTCATCGGCCCGTCGCTGGGAGGGGCGTC
GATACACACCCCGCTGGGCTACCGAGGACCGCTATGGGTCAGTGTGATGTTGGCGGCGCTGGCGCTCGTGGTCACGCTGT
GCGGGCTGCAGGCACGACGCCGAACTAGGAGGGCTGTAACGTCAGCGAGATCGAGTTGA

Upstream 100 bases:

>100_bases
TGCGACGTTGACCTTTCGGTCCGTCTGAACAAGTAGCAGCCGAACCAATCCCAGATGCTTTGCCGTCCCTATTCGGCCTA
CTCATCTGCACGGAGTTGTT

Downstream 100 bases:

>100_bases
TGAGACAGGCGAGGTAGCGCTTTTCAACTATTGGCGTGAGCGGTCAGTCCCGTGACGGAGTCGTTGAGCCCATGCCTTGG
AGGATATTTCGCGGATTTCG

Product: chloramphenicol resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTLPIYALTLAIFAQGCSEFMFAGLITEVGDDFGVSLAAAGTLTSAFAVGIIVGAPLMALISGRWPRRRALVLFLSVFIA
AHIVGATAASFPLLLIVRVVSAVANAGFLAVALTTAMSITGPRAKGRTTALLLSGITIACVAGVPGGAALGYFWGWRAAL
WAVVLVSVPALAAIMYALPVGRPVTGLPDGIGELRTLRNRRLQITLAAGVLCNAATFCAFTYLAPVSVQVTSLSPAWTPA
LLALFGCGSFVGVHATGRLADSHANLVAGGGGVLLLAGWIAFAGTAAHDWLFVTLVFALGALSFGVGSTLFSQGLYAASD
APMLGSSLTTAAFNVGTVIGPSLGGASIHTPLGYRGPLWVSVMLAALALVVTLCGLQARRRTRRAVTSARSS

Sequences:

>Translated_392_residues
MTLPIYALTLAIFAQGCSEFMFAGLITEVGDDFGVSLAAAGTLTSAFAVGIIVGAPLMALISGRWPRRRALVLFLSVFIA
AHIVGATAASFPLLLIVRVVSAVANAGFLAVALTTAMSITGPRAKGRTTALLLSGITIACVAGVPGGAALGYFWGWRAAL
WAVVLVSVPALAAIMYALPVGRPVTGLPDGIGELRTLRNRRLQITLAAGVLCNAATFCAFTYLAPVSVQVTSLSPAWTPA
LLALFGCGSFVGVHATGRLADSHANLVAGGGGVLLLAGWIAFAGTAAHDWLFVTLVFALGALSFGVGSTLFSQGLYAASD
APMLGSSLTTAAFNVGTVIGPSLGGASIHTPLGYRGPLWVSVMLAALALVVTLCGLQARRRTRRAVTSARSS
>Mature_391_residues
TLPIYALTLAIFAQGCSEFMFAGLITEVGDDFGVSLAAAGTLTSAFAVGIIVGAPLMALISGRWPRRRALVLFLSVFIAA
HIVGATAASFPLLLIVRVVSAVANAGFLAVALTTAMSITGPRAKGRTTALLLSGITIACVAGVPGGAALGYFWGWRAALW
AVVLVSVPALAAIMYALPVGRPVTGLPDGIGELRTLRNRRLQITLAAGVLCNAATFCAFTYLAPVSVQVTSLSPAWTPAL
LALFGCGSFVGVHATGRLADSHANLVAGGGGVLLLAGWIAFAGTAAHDWLFVTLVFALGALSFGVGSTLFSQGLYAASDA
PMLGSSLTTAAFNVGTVIGPSLGGASIHTPLGYRGPLWVSVMLAALALVVTLCGLQARRRTRRAVTSARSS

Specific function: Unknown

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787947, Length=391, Percent_Identity=30.9462915601023, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786595, Length=270, Percent_Identity=27.037037037037, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787808, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI145693198, Length=259, Percent_Identity=25.0965250965251, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 39928; Mature: 39796

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPIYALTLAIFAQGCSEFMFAGLITEVGDDFGVSLAAAGTLTSAFAVGIIVGAPLMAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISGRWPRRRALVLFLSVFIAAHIVGATAASFPLLLIVRVVSAVANAGFLAVALTTAMSIT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GPRAKGRTTALLLSGITIACVAGVPGGAALGYFWGWRAALWAVVLVSVPALAAIMYALPV
CCCCCCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRPVTGLPDGIGELRTLRNRRLQITLAAGVLCNAATFCAFTYLAPVSVQVTSLSPAWTPA
CCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
LLALFGCGSFVGVHATGRLADSHANLVAGGGGVLLLAGWIAFAGTAAHDWLFVTLVFALG
HHHHHHCCCCEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALSFGVGSTLFSQGLYAASDAPMLGSSLTTAAFNVGTVIGPSLGGASIHTPLGYRGPLWV
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHCCCCCCCCCCCCCCCCCCHHHH
SVMLAALALVVTLCGLQARRRTRRAVTSARSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLPIYALTLAIFAQGCSEFMFAGLITEVGDDFGVSLAAAGTLTSAFAVGIIVGAPLMAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISGRWPRRRALVLFLSVFIAAHIVGATAASFPLLLIVRVVSAVANAGFLAVALTTAMSIT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GPRAKGRTTALLLSGITIACVAGVPGGAALGYFWGWRAALWAVVLVSVPALAAIMYALPV
CCCCCCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRPVTGLPDGIGELRTLRNRRLQITLAAGVLCNAATFCAFTYLAPVSVQVTSLSPAWTPA
CCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
LLALFGCGSFVGVHATGRLADSHANLVAGGGGVLLLAGWIAFAGTAAHDWLFVTLVFALG
HHHHHHCCCCEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALSFGVGSTLFSQGLYAASDAPMLGSSLTTAAFNVGTVIGPSLGGASIHTPLGYRGPLWV
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHCCCCCCCCCCCCCCCCCCHHHH
SVMLAALALVVTLCGLQARRRTRRAVTSARSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1779766 [H]