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The map label for this gene is lgrD [H]

Identifier: 169630045

GI number: 169630045

Start: 3017425

End: 3020979

Strand: Direct

Name: lgrD [H]

Synonym: MAB_2962

Alternate gene names: 169630045

Gene position: 3017425-3020979 (Clockwise)

Preceding gene: 169630044

Following gene: 169630046

Centisome position: 59.55

GC content: 63.91

Gene sequence:

>3555_bases
ATGACCGTGACCAACGAAACCAACCCACAGCAGGAGCAGCTATCCCGCCGTATTGAAAGTCTGCGCGAAAGCGATCCGCA
GTTCCGGGCGGCCCAGCCCGACCCGGCGGTCGCCGAACAGGTGCTGCGCCCGGGCCTGCATCTTTCTGAAGCCATTGCGG
CGTTGATGACTGGATACGCTGAGCGCCCGGCGCTCGGTGAGCGCGCACGCGAGTTGGTCACCGACCAGGATGGCCGCACC
ACGCTGCGCCTGTTGCCACGCTTCGACACCACCACATACGGCGAATTATGGTCCCGCACAACATCAGTCGCCGCTGCATG
GCACCACGACGCCGCCCACCCGGTTAAGGCCGGCGATCTGGTGGCCACCCTGGGATTCACCAGCATCGACTACACCGTGC
TGGATCTGGCGATCATGATCCTCGGTGGCGTGGCGGTTCCGCTACAGACCAGCGCCCCGGCTTCGCAGTGGACGACCATT
CTGGCCGAAGCGGAACCCAACACTCTTGCGGTAAGCATCGAATTGATCGGCGCTGCAATGGAATCTGTGCGGGCCACGCC
TTCCATCAAGCAGGTCGTCGTGTTCGACTACACCCCCGAGGTCGATGATCAACGGGAGGCATTCGAGGCAGCAAGCACAC
AACTCGCCGGCACCGGCATCGCCATTGAGACCCTCGATGCCGTCATCGCCCGCGGCGCCGCACTTCCGGCCGCACCGCTC
TACGCACCATCGGCCGGCGACGATCCGCTGGCGCTGCTCATCTACACCTCCGGCAGCACCGGGGCTCCAAAGGGCGCCAT
GCACAGCGAAAACATCGTGCGCCGCTGGTGGATTCGTGAGGACGTCATGGCCGGCACCGAGAACCTGCCCATGATCGGGC
TGAACTTCATGCCGATGAGTCACATCATGGGACGCGGCACCCTCACCTCCACCCTGTCTACCGGTGGAACCGGATACTTC
GCGGCGTCCAGTGACATGTCAACGCTCTTCGAGGACATGGAGCTGATCCGCCCGACGGCCCTGGCCTTGGTTCCACGCGT
GTGCGACATGGTGTTCCAGCGATTCCAGACCGAGGTGGACCGGCGTCTGGCGAGCAGCGACACCGCCAGTGCCGAGGCCG
TTGCGGCCGAGGTCAAGGCCGATATCCGTGACAACCTCTTCGGTGGCCGCGTATCGGCGGTCATGGTCGGTTCTGCTCCG
TTGTCCGAGGAGCTGGGTGAGTTCATCGAATCCTGCTTCGAGCTGAATCTGACCGATGGCTACGGCTCCACCGAAGCCGG
CATGGTGTTCCGCGACGGCATCGTGCAACGCCCGCCGGTCATTGACTACAAGCTGGTTGACGTGCCCGAACTGGGCTACT
TCTCCACCGACAAGCCGCACCCGCGCGGTGAGCTGCTGCTGAAGACCGACGGCATGTTCCTCGGGTACTACAAACGCCCC
GAGGTGACTGCCGGCGTCTTCGACGCGGACGGTTTTTACATGACCGGCGACATCGTCGCCGAGCTGGCCCACGACAACAT
CGAGATCATCGATCGCCGCAACAACGTGCTCAAACTCTCACAGGGAGAGTTTGTCGCGGTCGCCACCTTGGAGGCCGAGT
ACGCCAATAGCCCTGTGGTGCACCAGATCTACGTCTACGGCAGCAGCGAACGGTCCTACCTGCTAGCAGTCGTGGTGCCG
ACGCCGGAGGCCGTGGCCGCCGCCAAGGGCGACGCGGCGGCACTCAAGACGACCATCGCGGACTCGCTGCAGGACATTGC
CAAGGAGATCCAGCTGCAGTCCTACGAAGTCCCCCGTGACTTCATCATCGAACCGCAGCCATTCACCCAGGGCAACGGCC
TGCTGACGGGTATCGCCAAGCTGGCGCGTCCGAACCTGAAGGCGCACTATGGACCGCGGCTGGAGCAGATGTACGCCGAA
ATCGCCGAGCAGCAGGCTGCCGAGCTTCGGGCGTTGCACGGAGTGGACCCAGACAAGCCCGCGCTGGAAACGGTCCTCAA
GGCGGCGCAGGCCCTGCTCGGCGTCTCGTCGGCCGAACTGGCCGCGGACGCGCATTTCACCGATCTAGGTGGCGATTCGC
TGTCCGCACTGTCCTTCTCGGATCTGCTGCGCGATATCTTCGCGGTCGAAGTACCGGTCGGAGTCATCGTCAGTGCCGCA
AACGATCTCAGCGGTGTTGCGAAATTTGTTGATGAACAACGCTATTCGGGCGGGACGCGGCCGACCGCGGAGACGGTGCA
CGGCGCCGGGCATACGGAGATCCGGGCCGCGGACCTGACCCTGGATAAGTTCATCGACGAGGCCACCCTGCATGCGGCAC
CGTCGCTTCCGAAGGCCGTCGGGATCCCACACACCGTCCTGCTCACCGGGTCCAACGGCTACCTGGGCCACTACCTGGCA
CTGGAATGGCTTGAGCGCCTGGACAAGACAGAAGGCAAGCTGATCGCCATCGTCCGCGGTAAGAATGCCGAGGCCGCCTA
CCGCCGCCTCGAGGAAGCCTTCGACACCGGCGACACGCAGCTGTTGGCGCACTTCCGGTCGCTGGCCGACAAGCACCTCG
AAGTACTGGCCGGCGATATCGGCGACCCCAACCTTGGCCTGGATGCCGACACCTGGCAGCGCCTGGCCGACACCGTCGAC
GTCATCGTGCACCCCGCCGCCCTGGTCAACCACGTACTGCCCTACAGCCAGCTGTTCGGACCGAATGTCGTCGGCACCGC
CGAGATCATCAAGCTGGCCATCACTACCAAGATCAAGCCGGTCACCTACCTGTCCACGGTCGCGGTCGCGGCATATGTCG
ATCCGACGACATTCGACGAAGAGTCCGATATCCGGCTCATCAGCGCGGTGCGTCCCGTGGACGAGCTGTACGCGAACGGC
TACGGCAACAGCAAGTGGGCCGGCGAGGTACTGCTGCGCGAAGCCCACGATCTGTGCGGACTACCCGTCGCGGTCTTCCG
CTCCGACATGATCTTGGCCCACAGCCGCTACACCGGACAGCTCAACGTGCCCGACCAGTTCACCCGACTAATCCTCAGCC
TCATCGCCACCGGAATCGCACCCGGCTCCTTCTACCAAGCACACGCCACCGGCGAACGCCCACTCGCCCACTACGACGGG
CTACCCGGTGACTTCACCGCCGAGGCGATCACCACGTTGGGCACCCAGGTGGTCGACAGCTACGAGACCTACGACTGCGT
GAACCCGCATGCAGACGGAGTCTCGCTGGACAACTTCGTCGACTGGCTCATCGAAGCCGGCTACCCCATCGCACGCATCG
ACAACTACACCGAATGGTTCACCCGCTTCGACACCGCCATCCGAAGCCTCCCCGAAAAACAGAAACAACACTCCCTACTA
CCACTGCTCCACGCATTCGAACAGCCGTCCGCCGCCGAGAACCACGGCGTCGTCCCGGCAAAGCGTTTCCAGCACGCTGT
GCAGGCCGCCGGAATCGGTCCGGCCGGGCAAGACGGCACTACCGACATTCCCCACCTGTCGCGGCGGCTGATCGTGAAAT
ACGCCAAGGACCTCGAACAGCTCGGACTCCTATGA

Upstream 100 bases:

>100_bases
GACACTGATTGTGAGGAATGCCATAGCTGAATATATCGTTAGTTTAGGTAATCTACTTTTCAGACTTCCCTGAGAACTCC
CTGTCGATTTGAGGCTGCCC

Downstream 100 bases:

>100_bases
CCCGCGCGCTTACAGAATCGACGGTTTCGTAAGCTGCCGATATGACGATCGACGCCACCGCGGACAACACCAAGGAAGCA
CGTCGTCAGCGGTTAGGCGA

Product: fatty-acid-CoA ligase FadD

Products: D-carnitinyl-CoA; crotonobetainyl-CoA; L-carnitinyl-CoA [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1184; Mature: 1183

Protein sequence:

>1184_residues
MTVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAEQVLRPGLHLSEAIAALMTGYAERPALGERARELVTDQDGRT
TLRLLPRFDTTTYGELWSRTTSVAAAWHHDAAHPVKAGDLVATLGFTSIDYTVLDLAIMILGGVAVPLQTSAPASQWTTI
LAEAEPNTLAVSIELIGAAMESVRATPSIKQVVVFDYTPEVDDQREAFEAASTQLAGTGIAIETLDAVIARGAALPAAPL
YAPSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIREDVMAGTENLPMIGLNFMPMSHIMGRGTLTSTLSTGGTGYF
AASSDMSTLFEDMELIRPTALALVPRVCDMVFQRFQTEVDRRLASSDTASAEAVAAEVKADIRDNLFGGRVSAVMVGSAP
LSEELGEFIESCFELNLTDGYGSTEAGMVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFLGYYKRP
EVTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEFVAVATLEAEYANSPVVHQIYVYGSSERSYLLAVVVP
TPEAVAAAKGDAAALKTTIADSLQDIAKEIQLQSYEVPRDFIIEPQPFTQGNGLLTGIAKLARPNLKAHYGPRLEQMYAE
IAEQQAAELRALHGVDPDKPALETVLKAAQALLGVSSAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAA
NDLSGVAKFVDEQRYSGGTRPTAETVHGAGHTEIRAADLTLDKFIDEATLHAAPSLPKAVGIPHTVLLTGSNGYLGHYLA
LEWLERLDKTEGKLIAIVRGKNAEAAYRRLEEAFDTGDTQLLAHFRSLADKHLEVLAGDIGDPNLGLDADTWQRLADTVD
VIVHPAALVNHVLPYSQLFGPNVVGTAEIIKLAITTKIKPVTYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANG
YGNSKWAGEVLLREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATGIAPGSFYQAHATGERPLAHYDG
LPGDFTAEAITTLGTQVVDSYETYDCVNPHADGVSLDNFVDWLIEAGYPIARIDNYTEWFTRFDTAIRSLPEKQKQHSLL
PLLHAFEQPSAAENHGVVPAKRFQHAVQAAGIGPAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL

Sequences:

>Translated_1184_residues
MTVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAEQVLRPGLHLSEAIAALMTGYAERPALGERARELVTDQDGRT
TLRLLPRFDTTTYGELWSRTTSVAAAWHHDAAHPVKAGDLVATLGFTSIDYTVLDLAIMILGGVAVPLQTSAPASQWTTI
LAEAEPNTLAVSIELIGAAMESVRATPSIKQVVVFDYTPEVDDQREAFEAASTQLAGTGIAIETLDAVIARGAALPAAPL
YAPSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIREDVMAGTENLPMIGLNFMPMSHIMGRGTLTSTLSTGGTGYF
AASSDMSTLFEDMELIRPTALALVPRVCDMVFQRFQTEVDRRLASSDTASAEAVAAEVKADIRDNLFGGRVSAVMVGSAP
LSEELGEFIESCFELNLTDGYGSTEAGMVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFLGYYKRP
EVTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEFVAVATLEAEYANSPVVHQIYVYGSSERSYLLAVVVP
TPEAVAAAKGDAAALKTTIADSLQDIAKEIQLQSYEVPRDFIIEPQPFTQGNGLLTGIAKLARPNLKAHYGPRLEQMYAE
IAEQQAAELRALHGVDPDKPALETVLKAAQALLGVSSAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAA
NDLSGVAKFVDEQRYSGGTRPTAETVHGAGHTEIRAADLTLDKFIDEATLHAAPSLPKAVGIPHTVLLTGSNGYLGHYLA
LEWLERLDKTEGKLIAIVRGKNAEAAYRRLEEAFDTGDTQLLAHFRSLADKHLEVLAGDIGDPNLGLDADTWQRLADTVD
VIVHPAALVNHVLPYSQLFGPNVVGTAEIIKLAITTKIKPVTYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANG
YGNSKWAGEVLLREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATGIAPGSFYQAHATGERPLAHYDG
LPGDFTAEAITTLGTQVVDSYETYDCVNPHADGVSLDNFVDWLIEAGYPIARIDNYTEWFTRFDTAIRSLPEKQKQHSLL
PLLHAFEQPSAAENHGVVPAKRFQHAVQAAGIGPAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL
>Mature_1183_residues
TVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAEQVLRPGLHLSEAIAALMTGYAERPALGERARELVTDQDGRTT
LRLLPRFDTTTYGELWSRTTSVAAAWHHDAAHPVKAGDLVATLGFTSIDYTVLDLAIMILGGVAVPLQTSAPASQWTTIL
AEAEPNTLAVSIELIGAAMESVRATPSIKQVVVFDYTPEVDDQREAFEAASTQLAGTGIAIETLDAVIARGAALPAAPLY
APSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIREDVMAGTENLPMIGLNFMPMSHIMGRGTLTSTLSTGGTGYFA
ASSDMSTLFEDMELIRPTALALVPRVCDMVFQRFQTEVDRRLASSDTASAEAVAAEVKADIRDNLFGGRVSAVMVGSAPL
SEELGEFIESCFELNLTDGYGSTEAGMVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFLGYYKRPE
VTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEFVAVATLEAEYANSPVVHQIYVYGSSERSYLLAVVVPT
PEAVAAAKGDAAALKTTIADSLQDIAKEIQLQSYEVPRDFIIEPQPFTQGNGLLTGIAKLARPNLKAHYGPRLEQMYAEI
AEQQAAELRALHGVDPDKPALETVLKAAQALLGVSSAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAAN
DLSGVAKFVDEQRYSGGTRPTAETVHGAGHTEIRAADLTLDKFIDEATLHAAPSLPKAVGIPHTVLLTGSNGYLGHYLAL
EWLERLDKTEGKLIAIVRGKNAEAAYRRLEEAFDTGDTQLLAHFRSLADKHLEVLAGDIGDPNLGLDADTWQRLADTVDV
IVHPAALVNHVLPYSQLFGPNVVGTAEIIKLAITTKIKPVTYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANGY
GNSKWAGEVLLREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATGIAPGSFYQAHATGERPLAHYDGL
PGDFTAEAITTLGTQVVDSYETYDCVNPHADGVSLDNFVDWLIEAGYPIARIDNYTEWFTRFDTAIRSLPEKQKQHSLLP
LLHAFEQPSAAENHGVVPAKRFQHAVQAAGIGPAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI57165412, Length=561, Percent_Identity=29.9465240641711, Blast_Score=198, Evalue=3e-50,
Organism=Homo sapiens, GI42794756, Length=562, Percent_Identity=29.5373665480427, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI42794760, Length=562, Percent_Identity=29.5373665480427, Blast_Score=197, Evalue=6e-50,
Organism=Homo sapiens, GI42794758, Length=562, Percent_Identity=29.5373665480427, Blast_Score=197, Evalue=6e-50,
Organism=Homo sapiens, GI57165410, Length=559, Percent_Identity=29.3381037567084, Blast_Score=196, Evalue=9e-50,
Organism=Homo sapiens, GI42794754, Length=700, Percent_Identity=26.2857142857143, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI42794752, Length=700, Percent_Identity=26.2857142857143, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI40807491, Length=560, Percent_Identity=28.75, Blast_Score=187, Evalue=7e-47,
Organism=Homo sapiens, GI12669909, Length=535, Percent_Identity=27.2897196261682, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI4758332, Length=535, Percent_Identity=27.2897196261682, Blast_Score=186, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17510401, Length=623, Percent_Identity=28.2504012841091, Blast_Score=201, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17556552, Length=544, Percent_Identity=29.4117647058824, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17564090, Length=447, Percent_Identity=29.3064876957494, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25147511, Length=536, Percent_Identity=27.7985074626866, Blast_Score=174, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17553312, Length=650, Percent_Identity=26.6153846153846, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17541856, Length=569, Percent_Identity=27.9437609841828, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI193204819, Length=599, Percent_Identity=25.3756260434057, Blast_Score=152, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320852, Length=595, Percent_Identity=26.7226890756303, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323903, Length=473, Percent_Identity=26.4270613107822, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319591, Length=667, Percent_Identity=23.688155922039, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322182, Length=477, Percent_Identity=26.8343815513627, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6324893, Length=526, Percent_Identity=24.3346007604563, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24666501, Length=454, Percent_Identity=31.2775330396476, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24666497, Length=454, Percent_Identity=31.2775330396476, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI281366413, Length=454, Percent_Identity=31.2775330396476, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI62471681, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62471687, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24586634, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI22026970, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62471689, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62471679, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI62471683, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI62471685, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24586636, Length=488, Percent_Identity=28.4836065573771, Blast_Score=168, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 6.3.2.- [C]

Molecular weight: Translated: 127906; Mature: 127775

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50075 ACP_DOMAIN ; PS00061 ADH_SHORT ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAEQVLRPGLHLSEAIAALMTGYA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
ERPALGERARELVTDQDGRTTLRLLPRFDTTTYGELWSRTTSVAAAWHHDAAHPVKAGDL
CCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
VATLGFTSIDYTVLDLAIMILGGVAVPLQTSAPASQWTTILAEAEPNTLAVSIELIGAAM
EEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEEEEECCCCEEEEEHHHHHHHH
ESVRATPSIKQVVVFDYTPEVDDQREAFEAASTQLAGTGIAIETLDAVIARGAALPAAPL
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
YAPSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIREDVMAGTENLPMIGLNFMPMS
CCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
HIMGRGTLTSTLSTGGTGYFAASSDMSTLFEDMELIRPTALALVPRVCDMVFQRFQTEVD
HHHCCCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLASSDTASAEAVAAEVKADIRDNLFGGRVSAVMVGSAPLSEELGEFIESCFELNLTDG
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCC
YGSTEAGMVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFLGYYKRP
CCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCC
EVTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEFVAVATLEAEYANSPVV
CCEEEEEECCCCEEHHHHHHHHHCCCEEEEECCCCEEEECCCCEEEEEEEEHHHCCCCCE
HQIYVYGSSERSYLLAVVVPTPEAVAAAKGDAAALKTTIADSLQDIAKEIQLQSYEVPRD
EEEEEEECCCCCEEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FIIEPQPFTQGNGLLTGIAKLARPNLKAHYGPRLEQMYAEIAEQQAAELRALHGVDPDKP
HEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ALETVLKAAQALLGVSSAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAA
HHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCHHHEEECC
NDLSGVAKFVDEQRYSGGTRPTAETVHGAGHTEIRAADLTLDKFIDEATLHAAPSLPKAV
HHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHH
GIPHTVLLTGSNGYLGHYLALEWLERLDKTEGKLIAIVRGKNAEAAYRRLEEAFDTGDTQ
CCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHH
LLAHFRSLADKHLEVLAGDIGDPNLGLDADTWQRLADTVDVIVHPAALVNHVLPYSQLFG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCC
PNVVGTAEIIKLAITTKIKPVTYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCCCCEEHHHHHCCHHHHHHCC
YGNSKWAGEVLLREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATGIA
CCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCC
PGSFYQAHATGERPLAHYDGLPGDFTAEAITTLGTQVVDSYETYDCVNPHADGVSLDNFV
CCCCEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
DWLIEAGYPIARIDNYTEWFTRFDTAIRSLPEKQKQHSLLPLLHAFEQPSAAENHGVVPA
HHHHHCCCCHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KRFQHAVQAAGIGPAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVTNETNPQQEQLSRRIESLRESDPQFRAAQPDPAVAEQVLRPGLHLSEAIAALMTGYA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
ERPALGERARELVTDQDGRTTLRLLPRFDTTTYGELWSRTTSVAAAWHHDAAHPVKAGDL
CCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
VATLGFTSIDYTVLDLAIMILGGVAVPLQTSAPASQWTTILAEAEPNTLAVSIELIGAAM
EEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEEEEECCCCEEEEEHHHHHHHH
ESVRATPSIKQVVVFDYTPEVDDQREAFEAASTQLAGTGIAIETLDAVIARGAALPAAPL
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
YAPSAGDDPLALLIYTSGSTGAPKGAMHSENIVRRWWIREDVMAGTENLPMIGLNFMPMS
CCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
HIMGRGTLTSTLSTGGTGYFAASSDMSTLFEDMELIRPTALALVPRVCDMVFQRFQTEVD
HHHCCCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLASSDTASAEAVAAEVKADIRDNLFGGRVSAVMVGSAPLSEELGEFIESCFELNLTDG
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCC
YGSTEAGMVFRDGIVQRPPVIDYKLVDVPELGYFSTDKPHPRGELLLKTDGMFLGYYKRP
CCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCC
EVTAGVFDADGFYMTGDIVAELAHDNIEIIDRRNNVLKLSQGEFVAVATLEAEYANSPVV
CCEEEEEECCCCEEHHHHHHHHHCCCEEEEECCCCEEEECCCCEEEEEEEEHHHCCCCCE
HQIYVYGSSERSYLLAVVVPTPEAVAAAKGDAAALKTTIADSLQDIAKEIQLQSYEVPRD
EEEEEEECCCCCEEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FIIEPQPFTQGNGLLTGIAKLARPNLKAHYGPRLEQMYAEIAEQQAAELRALHGVDPDKP
HEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ALETVLKAAQALLGVSSAELAADAHFTDLGGDSLSALSFSDLLRDIFAVEVPVGVIVSAA
HHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCHHHEEECC
NDLSGVAKFVDEQRYSGGTRPTAETVHGAGHTEIRAADLTLDKFIDEATLHAAPSLPKAV
HHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHH
GIPHTVLLTGSNGYLGHYLALEWLERLDKTEGKLIAIVRGKNAEAAYRRLEEAFDTGDTQ
CCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHH
LLAHFRSLADKHLEVLAGDIGDPNLGLDADTWQRLADTVDVIVHPAALVNHVLPYSQLFG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCC
PNVVGTAEIIKLAITTKIKPVTYLSTVAVAAYVDPTTFDEESDIRLISAVRPVDELYANG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCCCCEEHHHHHCCHHHHHHCC
YGNSKWAGEVLLREAHDLCGLPVAVFRSDMILAHSRYTGQLNVPDQFTRLILSLIATGIA
CCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCC
PGSFYQAHATGERPLAHYDGLPGDFTAEAITTLGTQVVDSYETYDCVNPHADGVSLDNFV
CCCCEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
DWLIEAGYPIARIDNYTEWFTRFDTAIRSLPEKQKQHSLLPLLHAFEQPSAAENHGVVPA
HHHHHCCCCHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KRFQHAVQAAGIGPAGQDGTTDIPHLSRRLIVKYAKDLEQLGLL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; D-carnitine; Coenzyme A; crotono-betaine; L-carnitine [C]

Specific reaction: Coenzyme A + D-carnitine = D-carnitinyl-CoA Coenzyme A + crotono-betaine = crotonobetainyl-CoA Coenzyme A + L-carnitine = L-carnitinyl-CoA [C]

General reaction: Ligases; Forming Carbon-Sulfur Bonds; Acid-Thiol Ligases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA