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The map label for this gene is ubiE [C]

Identifier: 169630044

GI number: 169630044

Start: 3016580

End: 3017176

Strand: Direct

Name: ubiE [C]

Synonym: MAB_2961

Alternate gene names: 169630044

Gene position: 3016580-3017176 (Clockwise)

Preceding gene: 169630043

Following gene: 169630045

Centisome position: 59.53

GC content: 63.15

Gene sequence:

>597_bases
ATGCCTACGACATGGATGGACACCGTGGTACGGCAAGTGCGCCGGGTCGGCGACTTTCCGTTCCCCCGCCAGGCTGCCCT
CGTGCTCGACAACCCCATTCACCGGAAGTTTGTGAACCCCGCCGGAGTGGCCGAGCAGTTGGCGCTGCACGGCGGCGAAC
ACGTGTTGGAGATCGGCCCGGGCCCTGGAATCTTCAGCGTGCACATCGCGTCACGACTCCCTTCCGGTCGACTCGAGCTG
TTCGACGTGCAGCCCGAAATGCTTGAAATGGTGAAGAGCAAGCTCGATCGCGCCGGATACCGGAACGCCGGATTCCATTC
CGGTGACGCCGGCAACGGTCTCCCCTTTTCCGACAACACTTTTGACGTCGCATTCCTGGCCAGCGTGATCGGCGAGGTGC
CGGACAAGGCGGCATGCGTCCGGTCATTGGCGCAGGTGCTCAAGCCCGGCGGGCGGCTGGTATTCCACGAGATCTTCCTC
GACCCCGATCGACTCGGAATCTCCGAACTCCGCTCCCTGGTCGAACCGGCAGGATTCACCTTCGCGGCGGCAACAGGAAG
CCGATGGCGCGACATCGTCGAATTCGCACGTACTTAG

Upstream 100 bases:

>100_bases
AGGCACCCAGCGCGGGGGGCGGCAACAGTGGTGGTGGCAGCGGCGGCGGGCGCCACTAGCGAGGGCTCCCCATCGCGCCA
AGTAAGGGTAGCCTTAGTTC

Downstream 100 bases:

>100_bases
ACACTCGACTCAGGCAGACACCCGACTTAGACACTCGGACAAAGCGCCCTCGGCCCCGCGTACTCCGGCCCGGACAGTCC
GCGCGCCAAGCCCGTCTTGC

Product: putative menaquinone biosynthesis methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Demethylmenaquinone Methyltransferase; Menaquinone Biosynthesis Methyltransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; UbiE/COQ5 Methyltransferase; Arsenite S-Adenosylmethyltransferase

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MPTTWMDTVVRQVRRVGDFPFPRQAALVLDNPIHRKFVNPAGVAEQLALHGGEHVLEIGPGPGIFSVHIASRLPSGRLEL
FDVQPEMLEMVKSKLDRAGYRNAGFHSGDAGNGLPFSDNTFDVAFLASVIGEVPDKAACVRSLAQVLKPGGRLVFHEIFL
DPDRLGISELRSLVEPAGFTFAAATGSRWRDIVEFART

Sequences:

>Translated_198_residues
MPTTWMDTVVRQVRRVGDFPFPRQAALVLDNPIHRKFVNPAGVAEQLALHGGEHVLEIGPGPGIFSVHIASRLPSGRLEL
FDVQPEMLEMVKSKLDRAGYRNAGFHSGDAGNGLPFSDNTFDVAFLASVIGEVPDKAACVRSLAQVLKPGGRLVFHEIFL
DPDRLGISELRSLVEPAGFTFAAATGSRWRDIVEFART
>Mature_197_residues
PTTWMDTVVRQVRRVGDFPFPRQAALVLDNPIHRKFVNPAGVAEQLALHGGEHVLEIGPGPGIFSVHIASRLPSGRLELF
DVQPEMLEMVKSKLDRAGYRNAGFHSGDAGNGLPFSDNTFDVAFLASVIGEVPDKAACVRSLAQVLKPGGRLVFHEIFLD
PDRLGISELRSLVEPAGFTFAAATGSRWRDIVEFART

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21616; Mature: 21485

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTWMDTVVRQVRRVGDFPFPRQAALVLDNPIHRKFVNPAGVAEQLALHGGEHVLEIGP
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHCCHHHHHHHHHHCCCCEEEEECC
GPGIFSVHIASRLPSGRLELFDVQPEMLEMVKSKLDRAGYRNAGFHSGDAGNGLPFSDNT
CCCEEEEEHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
FDVAFLASVIGEVPDKAACVRSLAQVLKPGGRLVFHEIFLDPDRLGISELRSLVEPAGFT
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCHHHHHHHHCCCCCE
FAAATGSRWRDIVEFART
EEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
PTTWMDTVVRQVRRVGDFPFPRQAALVLDNPIHRKFVNPAGVAEQLALHGGEHVLEIGP
CCHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHCCHHHHHHHHHHCCCCEEEEECC
GPGIFSVHIASRLPSGRLELFDVQPEMLEMVKSKLDRAGYRNAGFHSGDAGNGLPFSDNT
CCCEEEEEHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
FDVAFLASVIGEVPDKAACVRSLAQVLKPGGRLVFHEIFLDPDRLGISELRSLVEPAGFT
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCHHHHHHHHCCCCCE
FAAATGSRWRDIVEFART
EEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA