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The map label for this gene is ygfU [H]

Identifier: 169630015

GI number: 169630015

Start: 2986490

End: 2988484

Strand: Reverse

Name: ygfU [H]

Synonym: MAB_2932c

Alternate gene names: 169630015

Gene position: 2988484-2986490 (Counterclockwise)

Preceding gene: 169630016

Following gene: 169630014

Centisome position: 58.98

GC content: 63.76

Gene sequence:

>1995_bases
ATGAGCGCCGATACCACGCGACCGGCCGCGCCCGGAGCCCAGCGCAAGAAGGTTCATCCCGTTGACGAGGTGCCTTCGAC
AGGCAGACTTGTCACGTTGGGCATCCAGCATGTGATCGCGTTCTACGCCGGCGCGGTATTGGTGCCGTTGCTCATCGCAC
GTGCCATCGATCTGGATGCCGAGGCGCTGACCATGTTGATCACCGCCGACCTATTCACCTGTGGTGTCGCCTCGATCCTG
CAGGCGGTTGGGTTCTGGAAGATCGGGGTGCGGCTGCCGCTACTGCAGGGGGTCACCTTTGCCACCCTGGCGCCGGTGAT
CAAAATCGCCAACGACCACGGTGGCGGCAGAGTCGGATTGCTCACGGTGTACGGCGCCGTCATCGCGGCGGGAGCGTTCA
CCTTCCTTATCGCACCGTTCTTCGCCCGGCTCATCCGATTCTTTCCACCTGTCGTGACCGGCTCGGTGATCACCATCATC
GGCGTATCGCTGCTGCCGGTGGGTATCGGCGACGCCACCCGTAACCCGCATAGCCCGGTCGCCGCGCACGATCCTGGTAA
CGGGCGCTGGCTCATGTACGCGCTGGGCACCATCGGGGCGATTGTGTTGATGCAGAGATTTTTCCGGGGCTTCTGGAGCA
CCATCGCGGTGCTGCTGGGGCTGGTCGCGGGCACCGTTGTCGCATGGCTGGCCGGGGACACGGACTTCGGCCGTGTCGGT
GAGGCGGACTGGATCGGATTCACGTCGCCGTTTGCCTTCGGCGCGCCGCGCTTCGATGTGATCGCCGTGGTATCGCTAAT
CGTGGTGCTGATGGTGACCGCGGTGGAGTCCACCGGTGCGGTCTTCGCCACGGCCGAGATCGTGGGCAAGCGGGTGCGCG
GGGCCGATATCGCCGCGACCGTGCGCGCCGATGGCATCGCCACCGTGATCGGCGGCACCTTCAACTCCTTTCCCTATACC
GCGTTCTCGGAGAATGTCGGACTGGTGCGCCTGACCGGTGTCAAGAGCCGTTGGGTGGTAGCGGCCGCGGGGGTGATCAT
GATGGTGTTGGGTGTGCTGCCCAAGACCGCCAAGATCGTGGAGTCGATTCCGGCCCCGGTGCTGGGCGGGGCTGCCATGA
CGCTGTTCGCGACGGTGGCCGTGGTCGGTATCCAGACCTTGGGCAAGGTCGACTTCAATGATCACCGGAATTTGATCATC
GCCAGCACCTCACTGGCCATGGGCATGTACGTGCAGTTCTCCCAATCTTCGGGCCCGGCAACAGTGCTGGACCACGGCCG
CGGCATCGCGGTACCCGCGCTGCCGGGAATCGACCAGGCCGTGCCGGGGCTACTGCAGATTCCGTTCAGCACCGGCATCA
CGATGGGCGCCATCACGGCCATCGTGCTGAATCTGCTGTTCTTCCATACGGGCAGCCGTGGCGTCGCGGTCGCCGGGGGA
GGTGCCATTCGGCTCGCGCAGGTCAACGAGATGACACTGGAGCAGTTTCGACGTACTTTCGGTGGCCTGGTTCAGGATGT
GCATTGGGTGGTGGATCGCGCCTATCGGCAGCGTCCCTTTGCCGACGCGCACGATTTGCGGAGTGCTTTTCAGGAAGCAA
TGCTCACCGGCAGCGACGAGGAGCAGCTCGAACTCATCGGATCCTTCCCCGATCTGGGCGCCGAGGACGAAGCTGGAGAG
ATGGTGGCCGTGGATCACACGATTCTGCAGACGCTCGACGAGGCCGAGCTGAACAATGTGGTGAGCCTTGCCACTGCCTA
TCGCGAGCATTTCGGCTTCCCGCTGGTGGTGTGTGCGAGGGAGACCGAACGGTATGAACGGCTGCTCCGCAGCGGCTGGA
GCCGGATGGAGAATTCGGCGACCAGCGAGCGCTCCTTTGCCCTCATCGAGATCGCGAAGATCGCCAACTACCGATTCGAT
GATCTGGTGGCCGATGCCAATCCCATCACGGCCGCTCGTTTCGGGCGCTTCGAGGATTTTCATGCGACGCGTTGA

Upstream 100 bases:

>100_bases
ATATAGGCAGCCGGCAACCTGGCCGCAACACGTTCGATCTAGCGTCGCTTGCGCGTCCGGGTGGGTATGCGCGGGTGCGT
CGAGGCAGGGAGGTTCCGCG

Downstream 100 bases:

>100_bases
CTGGCGGGGAATCGAGAGCTTCAACGAGCTCAGCGACAACCAGGCGATCCATTGGCTGTACGAGTGCTGCGCGTCGCGGA
TATGGGCGGTACGGGTTGCC

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPLLIARAIDLDAEALTMLITADLFTCGVASIL
QAVGFWKIGVRLPLLQGVTFATLAPVIKIANDHGGGRVGLLTVYGAVIAAGAFTFLIAPFFARLIRFFPPVVTGSVITII
GVSLLPVGIGDATRNPHSPVAAHDPGNGRWLMYALGTIGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVG
EADWIGFTSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKRVRGADIAATVRADGIATVIGGTFNSFPYT
AFSENVGLVRLTGVKSRWVVAAAGVIMMVLGVLPKTAKIVESIPAPVLGGAAMTLFATVAVVGIQTLGKVDFNDHRNLII
ASTSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGIDQAVPGLLQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGG
GAIRLAQVNEMTLEQFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDEEQLELIGSFPDLGAEDEAGE
MVAVDHTILQTLDEAELNNVVSLATAYREHFGFPLVVCARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFD
DLVADANPITAARFGRFEDFHATR

Sequences:

>Translated_664_residues
MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPLLIARAIDLDAEALTMLITADLFTCGVASIL
QAVGFWKIGVRLPLLQGVTFATLAPVIKIANDHGGGRVGLLTVYGAVIAAGAFTFLIAPFFARLIRFFPPVVTGSVITII
GVSLLPVGIGDATRNPHSPVAAHDPGNGRWLMYALGTIGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVG
EADWIGFTSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKRVRGADIAATVRADGIATVIGGTFNSFPYT
AFSENVGLVRLTGVKSRWVVAAAGVIMMVLGVLPKTAKIVESIPAPVLGGAAMTLFATVAVVGIQTLGKVDFNDHRNLII
ASTSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGIDQAVPGLLQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGG
GAIRLAQVNEMTLEQFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDEEQLELIGSFPDLGAEDEAGE
MVAVDHTILQTLDEAELNNVVSLATAYREHFGFPLVVCARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFD
DLVADANPITAARFGRFEDFHATR
>Mature_663_residues
SADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPLLIARAIDLDAEALTMLITADLFTCGVASILQ
AVGFWKIGVRLPLLQGVTFATLAPVIKIANDHGGGRVGLLTVYGAVIAAGAFTFLIAPFFARLIRFFPPVVTGSVITIIG
VSLLPVGIGDATRNPHSPVAAHDPGNGRWLMYALGTIGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVGE
ADWIGFTSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKRVRGADIAATVRADGIATVIGGTFNSFPYTA
FSENVGLVRLTGVKSRWVVAAAGVIMMVLGVLPKTAKIVESIPAPVLGGAAMTLFATVAVVGIQTLGKVDFNDHRNLIIA
STSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGIDQAVPGLLQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGGG
AIRLAQVNEMTLEQFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDEEQLELIGSFPDLGAEDEAGEM
VAVDHTILQTLDEAELNNVVSLATAYREHFGFPLVVCARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFDD
LVADANPITAARFGRFEDFHATR

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=530, Percent_Identity=24.1509433962264, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI40316845, Length=530, Percent_Identity=24.1509433962264, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI44680143, Length=183, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI44680145, Length=183, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI87082181, Length=470, Percent_Identity=39.5744680851064, Blast_Score=333, Evalue=3e-92,
Organism=Escherichia coli, GI1790087, Length=476, Percent_Identity=28.1512605042017, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788843, Length=405, Percent_Identity=28.641975308642, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081818, Length=405, Percent_Identity=28.8888888888889, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87082178, Length=456, Percent_Identity=26.3157894736842, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17541904, Length=454, Percent_Identity=22.6872246696035, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17558856, Length=440, Percent_Identity=23.1818181818182, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17542262, Length=446, Percent_Identity=23.0941704035874, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17542260, Length=239, Percent_Identity=24.2677824267782, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71993493, Length=238, Percent_Identity=23.9495798319328, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356175, Length=510, Percent_Identity=22.3529411764706, Blast_Score=80, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 70498; Mature: 70366

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPLLIARAIDLDA
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EALTMLITADLFTCGVASILQAVGFWKIGVRLPLLQGVTFATLAPVIKIANDHGGGRVGL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHCCHHHHHHHHHHEECCCCCCEEHH
LTVYGAVIAAGAFTFLIAPFFARLIRFFPPVVTGSVITIIGVSLLPVGIGDATRNPHSPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHEECCCCCCCCCCCCC
AAHDPGNGRWLMYALGTIGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVG
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EADWIGFTSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKRVRGADIAAT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCEEEE
VRADGIATVIGGTFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIMMVLGVLPKTAKIV
EECCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHH
ESIPAPVLGGAAMTLFATVAVVGIQTLGKVDFNDHRNLIIASTSLAMGMYVQFSQSSGPA
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHEEEEEEEECCCCCE
TVLDHGRGIAVPALPGIDQAVPGLLQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGG
EEHCCCCEEECCCCCCCHHHCCCCEECCHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
GAIRLAQVNEMTLEQFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
EQLELIGSFPDLGAEDEAGEMVAVDHTILQTLDEAELNNVVSLATAYREHFGFPLVVCAR
HHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECH
ETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFDDLVADANPITAARFGRFEDF
HHHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHCCCHHHHHCCCCCCHHHHCCCCCHH
HATR
CCCC
>Mature Secondary Structure 
SADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPLLIARAIDLDA
CCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EALTMLITADLFTCGVASILQAVGFWKIGVRLPLLQGVTFATLAPVIKIANDHGGGRVGL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHCCHHHHHHHHHHEECCCCCCEEHH
LTVYGAVIAAGAFTFLIAPFFARLIRFFPPVVTGSVITIIGVSLLPVGIGDATRNPHSPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHEECCCCCCCCCCCCC
AAHDPGNGRWLMYALGTIGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVG
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EADWIGFTSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKRVRGADIAAT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCEEEE
VRADGIATVIGGTFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIMMVLGVLPKTAKIV
EECCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHH
ESIPAPVLGGAAMTLFATVAVVGIQTLGKVDFNDHRNLIIASTSLAMGMYVQFSQSSGPA
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHEEEEEEEECCCCCE
TVLDHGRGIAVPALPGIDQAVPGLLQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGG
EEHCCCCEEECCCCCCCHHHCCCCEECCHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
GAIRLAQVNEMTLEQFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
EQLELIGSFPDLGAEDEAGEMVAVDHTILQTLDEAELNNVVSLATAYREHFGFPLVVCAR
HHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECH
ETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFDDLVADANPITAARFGRFEDF
HHHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHCCCHHHHHCCCCCCHHHHCCCCCHH
HATR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]