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The map label for this gene is ruvC [H]

Identifier: 169629968

GI number: 169629968

Start: 2938763

End: 2939272

Strand: Reverse

Name: ruvC [H]

Synonym: MAB_2884c

Alternate gene names: 169629968

Gene position: 2939272-2938763 (Counterclockwise)

Preceding gene: 169629970

Following gene: 169629967

Centisome position: 58.01

GC content: 65.88

Gene sequence:

>510_bases
ATGGTCGAGGCATCCTCGGGTCGCAAGGTGGTGGCCCTGGATGTCGACGTCGTTCGCACTCCCGCCAACCAGCCGCTGCC
GCAACGACTTCTAGTGATCAGTGAGGTCGTTGAACATTGGATGGAGACTCATCGCCCCGACGTCGTTGCCATCGAGCGCG
TCTTCGCCCAGCAGAACGTCTCCACCGTGATGGGCACGGCGCAAGCCGGCGGGGTGATCGCGCTCTGCGCCGCAAAACGG
GGGATCGAGGTGTATTTCCACACCCCGTCGGAGGTCAAGGCGGCGGTCACCGGCAACGGCCGGGCCGACAAATCCCAGGT
GACCGCGATGGTCACCCGCATCCTGAATCTGCAGGCCGCGCCCAAACCCGCGGATGCCGCCGACGCGCTGGCCCTGGCAA
TCTGTCACTGCTGGCGCGCGCCCATGCTTGCGAGAATGGCCAAGGCGGAAGCCGTGGCAGAGGAACAACGGAAGGCCTTC
GCGGCCCGGATGAAGGCAGCGGCTCGGTAA

Upstream 100 bases:

>100_bases
ACCTCCTCGATATGCTGATCGAACAACTGTTCTACAGCGAGAGGGCTGACGCGTGCGAGTAATGGGAGTCGACCCGGGTC
TTACCCGGTGCGGTCTGTCC

Downstream 100 bases:

>100_bases
TGGCAGGTCTGCGTAAAGAACGGAGTGCGGCGTGATTGCATCGGTCAACGGCGAGGTCATCGACATCGCGCTCGACCATG
TGGTGATCGAGGCGGCCGGC

Product: crossover junction endodeoxyribonuclease RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MVEASSGRKVVALDVDVVRTPANQPLPQRLLVISEVVEHWMETHRPDVVAIERVFAQQNVSTVMGTAQAGGVIALCAAKR
GIEVYFHTPSEVKAAVTGNGRADKSQVTAMVTRILNLQAAPKPADAADALALAICHCWRAPMLARMAKAEAVAEEQRKAF
AARMKAAAR

Sequences:

>Translated_169_residues
MVEASSGRKVVALDVDVVRTPANQPLPQRLLVISEVVEHWMETHRPDVVAIERVFAQQNVSTVMGTAQAGGVIALCAAKR
GIEVYFHTPSEVKAAVTGNGRADKSQVTAMVTRILNLQAAPKPADAADALALAICHCWRAPMLARMAKAEAVAEEQRKAF
AARMKAAAR
>Mature_169_residues
MVEASSGRKVVALDVDVVRTPANQPLPQRLLVISEVVEHWMETHRPDVVAIERVFAQQNVSTVMGTAQAGGVIALCAAKR
GIEVYFHTPSEVKAAVTGNGRADKSQVTAMVTRILNLQAAPKPADAADALALAICHCWRAPMLARMAKAEAVAEEQRKAF
AARMKAAAR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=116, Percent_Identity=35.3448275862069, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18107; Mature: 18107

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEASSGRKVVALDVDVVRTPANQPLPQRLLVISEVVEHWMETHRPDVVAIERVFAQQNV
CCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
STVMGTAQAGGVIALCAAKRGIEVYFHTPSEVKAAVTGNGRADKSQVTAMVTRILNLQAA
HHHHHCCCCCCEEEEEECCCCCEEEEECCCHHEEEECCCCCCCHHHHHHHHHHHHHCCCC
PKPADAADALALAICHCWRAPMLARMAKAEAVAEEQRKAFAARMKAAAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVEASSGRKVVALDVDVVRTPANQPLPQRLLVISEVVEHWMETHRPDVVAIERVFAQQNV
CCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
STVMGTAQAGGVIALCAAKRGIEVYFHTPSEVKAAVTGNGRADKSQVTAMVTRILNLQAA
HHHHHCCCCCCEEEEEECCCCCEEEEECCCHHEEEECCCCCCCHHHHHHHHHHHHHCCCC
PKPADAADALALAICHCWRAPMLARMAKAEAVAEEQRKAFAARMKAAAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA