| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is hdl IVa [H]
Identifier: 169629947
GI number: 169629947
Start: 2916420
End: 2917097
Strand: Direct
Name: hdl IVa [H]
Synonym: MAB_2863
Alternate gene names: 169629947
Gene position: 2916420-2917097 (Clockwise)
Preceding gene: 169629946
Following gene: 169629951
Centisome position: 57.56
GC content: 64.9
Gene sequence:
>678_bases TTGCGCTACAAGGCATACCTGTTCGACGTGCAAGGCACACTGCTCGACTTCTTCGAACCGGTATCGCGGGCGGTCGCCGA GTACTCCCCCGATGTCGACGCCGCCGCGTTCACGCGGGCCTGGCGTGCGGACTACTTCGAGCGGGTCTCGAGTCTGACTC AGTCCGCCGACCACTGGACACGCGTGCAGGACCTCTACGCGGCCGGTTTCGCTGATGTCTGCCAGACATTTGGGCTACCG TGTCCGGACACCGCGACCGCCGAGGATGTTGCATCCAGCTGGCAACGTCTGGTTCCATGGCCCGACGTACCCGCGGGCCT TGCGGCCCTGCGGATGCGGGCCGTCGTCGCGACCCTGTCCAACACCGATATGGCCACCATGGTGAACCTGTTCAAACGCC TGGACATTTCGTGGGACGCGATTTTCACCGCCGAGGTATTCGGGCGCTTCAAACCGGACCCGTCGGTGTACCGGGGCGCA CTGCGCTACCTGGGCGTTGAGCCGTACGAAGCGGCCATGGTGGCGGCGCACCCCTACGACCTGCGGGCCGCACGACAGCT CGGCATGGGCACGATCTTCGTCTCGCGGCCGCACGAATACGGTGACCCGGTCCTGGCGCACACCGATCCCGATGAAGAAT TCGATCAGCGAGTCACCGCTATCGGGGAGCTCTCCTAA
Upstream 100 bases:
>100_bases ACCGGGCAAAGTTATCGCGGTCCTTCCTCGATCCCCGTCATCGAGGTCACCGGGGTAACCCGCACCGATCCGCCCAAGAG CACCTACTGAGGGAGTCGCG
Downstream 100 bases:
>100_bases CGGTATCCGCGCGGTCGCACCCACAAGACCAGCACGCCCGCCAGCACAATGCCGAAGAGGTTGACGGCCAGCTGAAGCGC CGACAGTCCGGCAATATCCC
Product: HAD-superfamily hydrolase YfnB
Products: NA
Alternate protein names: 2-haloalkanoic acid dehalogenase IVA; Halocarboxylic acid halidohydrolase IVA; L-2-haloacid dehalogenase IVA [H]
Number of amino acids: Translated: 225; Mature: 225
Protein sequence:
>225_residues MRYKAYLFDVQGTLLDFFEPVSRAVAEYSPDVDAAAFTRAWRADYFERVSSLTQSADHWTRVQDLYAAGFADVCQTFGLP CPDTATAEDVASSWQRLVPWPDVPAGLAALRMRAVVATLSNTDMATMVNLFKRLDISWDAIFTAEVFGRFKPDPSVYRGA LRYLGVEPYEAAMVAAHPYDLRAARQLGMGTIFVSRPHEYGDPVLAHTDPDEEFDQRVTAIGELS
Sequences:
>Translated_225_residues MRYKAYLFDVQGTLLDFFEPVSRAVAEYSPDVDAAAFTRAWRADYFERVSSLTQSADHWTRVQDLYAAGFADVCQTFGLP CPDTATAEDVASSWQRLVPWPDVPAGLAALRMRAVVATLSNTDMATMVNLFKRLDISWDAIFTAEVFGRFKPDPSVYRGA LRYLGVEPYEAAMVAAHPYDLRAARQLGMGTIFVSRPHEYGDPVLAHTDPDEEFDQRVTAIGELS >Mature_225_residues MRYKAYLFDVQGTLLDFFEPVSRAVAEYSPDVDAAAFTRAWRADYFERVSSLTQSADHWTRVQDLYAAGFADVCQTFGLP CPDTATAEDVASSWQRLVPWPDVPAGLAALRMRAVVATLSNTDMATMVNLFKRLDISWDAIFTAEVFGRFKPDPSVYRGA LRYLGVEPYEAAMVAAHPYDLRAARQLGMGTIFVSRPHEYGDPVLAHTDPDEEFDQRVTAIGELS
Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-3 [H]
COG id: COG1011
COG function: function code R; Predicted hydrolase (HAD superfamily)
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005834 - InterPro: IPR023214 - InterPro: IPR006439 - InterPro: IPR006388 - InterPro: IPR006402 - InterPro: IPR006328 - InterPro: IPR005833 [H]
Pfam domain/function: PF00702 Hydrolase [H]
EC number: =3.8.1.2 [H]
Molecular weight: Translated: 25117; Mature: 25117
Theoretical pI: Translated: 4.52; Mature: 4.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRYKAYLFDVQGTLLDFFEPVSRAVAEYSPDVDAAAFTRAWRADYFERVSSLTQSADHWT CCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH RVQDLYAAGFADVCQTFGLPCPDTATAEDVASSWQRLVPWPDVPAGLAALRMRAVVATLS HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC NTDMATMVNLFKRLDISWDAIFTAEVFGRFKPDPSVYRGALRYLGVEPYEAAMVAAHPYD CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHEECCCHH LRAARQLGMGTIFVSRPHEYGDPVLAHTDPDEEFDQRVTAIGELS HHHHHHCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHCCC >Mature Secondary Structure MRYKAYLFDVQGTLLDFFEPVSRAVAEYSPDVDAAAFTRAWRADYFERVSSLTQSADHWT CCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH RVQDLYAAGFADVCQTFGLPCPDTATAEDVASSWQRLVPWPDVPAGLAALRMRAVVATLS HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC NTDMATMVNLFKRLDISWDAIFTAEVFGRFKPDPSVYRGALRYLGVEPYEAAMVAAHPYD CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHEECCCHH LRAARQLGMGTIFVSRPHEYGDPVLAHTDPDEEFDQRVTAIGELS HHHHHHCCCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1376111 [H]