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The map label for this gene is aroQ

Identifier: 169629924

GI number: 169629924

Start: 2889929

End: 2890363

Strand: Reverse

Name: aroQ

Synonym: MAB_2840c

Alternate gene names: 169629924

Gene position: 2890363-2889929 (Counterclockwise)

Preceding gene: 169629925

Following gene: 169629922

Centisome position: 57.04

GC content: 62.53

Gene sequence:

>435_bases
ATGACGATTCAGGTTCTCAATGGACCCAATCTGGGGCGTCTGGGTAAACGAGAGGCCGCCGTCTACGGCAGCGTCACCTA
CGCCGAGCTGGTATCGCTCATCGAGGCGGAGGCCGCGGTGCTGGGTGTTGACGTCCAGGTGCGCCAAAGCGATAGCGAGG
CCGAACTGCTCGGCTGGGTGCATGATGCCGCCGATGCTAAGGATCCCGTCATCCTCAACGCCGGTGCGTTCACCCATACG
TCGGTGGCGCTACGGGACGCGTGCGCCGAACTGAGCGCGGGACTGATAGAGGTGCATATCTCGAATGTGCATGCGCGCGA
AGAGTTCCGACACCACTCATACCTCAGTGCGTTGGCCACCGGCGTCATCGTCGGGCTCGGTGTCCAGGGCTATCTACTGG
CCCTGCGCTACTTCGTGGCGTCTGCCTCTTCCTGA

Upstream 100 bases:

>100_bases
GATTGGCCAAGCCGGGACGTTTGGAAGGTCCGGATCCGTCGCTGCTGGCAGCCGCCTATTCGGTGGTGGCGGGCGAGGCG
CGCGGCGAAGGAGTCCTGCT

Downstream 100 bases:

>100_bases
ACCGCCTGGAACACGTCGGTATCGGACTGCTGCAGCGCGGCGTGTTCCTTGTGCTTGCGGTCCACCAGTAGCCGGCCCGC
GAAGACACCGGCCATGGCCG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MTIQVLNGPNLGRLGKREAAVYGSVTYAELVSLIEAEAAVLGVDVQVRQSDSEAELLGWVHDAADAKDPVILNAGAFTHT
SVALRDACAELSAGLIEVHISNVHAREEFRHHSYLSALATGVIVGLGVQGYLLALRYFVASASS

Sequences:

>Translated_144_residues
MTIQVLNGPNLGRLGKREAAVYGSVTYAELVSLIEAEAAVLGVDVQVRQSDSEAELLGWVHDAADAKDPVILNAGAFTHT
SVALRDACAELSAGLIEVHISNVHAREEFRHHSYLSALATGVIVGLGVQGYLLALRYFVASASS
>Mature_143_residues
TIQVLNGPNLGRLGKREAAVYGSVTYAELVSLIEAEAAVLGVDVQVRQSDSEAELLGWVHDAADAKDPVILNAGAFTHTS
VALRDACAELSAGLIEVHISNVHAREEFRHHSYLSALATGVIVGLGVQGYLLALRYFVASASS

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_MYCA9 (B1MCE8)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703573.1
- ProteinModelPortal:   B1MCE8
- SMR:   B1MCE8
- EnsemblBacteria:   EBMYCT00000007421
- GeneID:   5965348
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2840c
- GeneTree:   EBGT00050000017464
- HOGENOM:   HBG284657
- OMA:   GWLHEAA
- ProtClustDB:   PRK05395
- BioCyc:   MABS561007:MAB_2840C-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15213; Mature: 15082

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQVLNGPNLGRLGKREAAVYGSVTYAELVSLIEAEAAVLGVDVQVRQSDSEAELLGWV
CEEEEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHEEECEEEEECCCCHHHHHHHH
HDAADAKDPVILNAGAFTHTSVALRDACAELSAGLIEVHISNVHAREEFRHHSYLSALAT
HHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHH
GVIVGLGVQGYLLALRYFVASASS
HHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIQVLNGPNLGRLGKREAAVYGSVTYAELVSLIEAEAAVLGVDVQVRQSDSEAELLGWV
EEEEECCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHEEECEEEEECCCCHHHHHHHH
HDAADAKDPVILNAGAFTHTSVALRDACAELSAGLIEVHISNVHAREEFRHHSYLSALAT
HHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHH
GVIVGLGVQGYLLALRYFVASASS
HHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA