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The map label for this gene is aroB [H]

Identifier: 169629925

GI number: 169629925

Start: 2890360

End: 2891478

Strand: Reverse

Name: aroB [H]

Synonym: MAB_2841c

Alternate gene names: 169629925

Gene position: 2891478-2890360 (Counterclockwise)

Preceding gene: 169629926

Following gene: 169629924

Centisome position: 57.06

GC content: 66.31

Gene sequence:

>1119_bases
ATGACTAGCGCCAACCCGACGACGATCACCGTCGAGGTGAACCCGCCTTACCCGGTCATCGTGGGGACGGGTCTGCTGGG
TGAGTTGGTGGATAATCTGAAGGGCTCGCAGGGGCTAGCCAAGGTGGCGATCCTGCACCAGCCGACCCTGGCGGTCACCG
CCGAGGAAATTCGCAAGACGCTGGCCGACAGCGGCATCGATGCGCATCGCGTCGAGATCCCCGATGCGGAGGCGGGCAAG
GACTTGGCCGTCCTCGGTTTCATCTGGGAAGTGTTGGGCCGCATCGGAATCGGACGCAAGGACGCCGTGGTGAGCCTCGG
GGGAGGGGCGGCAACCGACACGGCGGGATTCGCCGCCGCCACGTGGCTGCGCGGGATCAAGGTGGTGCACGTGCCCACCA
CGCTGCTGGCCATGGTCGATGCCGCGGTCGGCGGAAAGACCGGTATCAACACCGAGGCCGGCAAGAATCTCGTCGGCGCA
TTTCATCAGCCGGGTGCCGTACTGGTTGACTTGGCGACCCTCGAGTCATTGCCGCGTAACGAGATCATCGCGGGCATGGC
CGAAGTGGTGAAGGCCGGTTTCATCGCAGATCCGGTGATCCTCGACCTCATCGAGGCCGACCCGGAGACGGCGATCGACC
CGTCCAAGCCCGTGCTGCGCGAACTCGTCGAACGCTCCATCGCGGTCAAGGCCACGGTGGTGGCGGCCGACGAGAAGGAA
GCCGAGCTGCGCGAAATCCTCAACTATGGCCACACGCTCGGCCATGCCATCGAGCGCCGTGAGCGGTACCGCTGGCGTCA
CGGCGCCGCGGTCTCGGTGGGGCTGGTGTTCGCCGCCGAACTGGGCCGCTTGGCGGGCCGCCTGGACGATGAAACCGCCG
ATCGTCATGCTCGGGTGCTCTCGGCGCTGGGGCTGCCGGTCAGCTACGACGCCGATGCGCTGGGCCAGCTCGTCGAATAT
ATGCAGGGCGACAAGAAGACCCGCTCGGGCATACTGCGTTTCGTGGTGCTTGACGGATTGGCCAAGCCGGGACGTTTGGA
AGGTCCGGATCCGTCGCTGCTGGCAGCCGCCTATTCGGTGGTGGCGGGCGAGGCGCGCGGCGAAGGAGTCCTGCTATGA

Upstream 100 bases:

>100_bases
CGCCCGCGCCGGCGCCCCCGTTCGCGGCGGCGTAGCGCAGGCGCTGCGGCGGTAACCCAAACCAATACCTCCGGAACCGA
AACCAGGGAGAGAGCCGACA

Downstream 100 bases:

>100_bases
CGATTCAGGTTCTCAATGGACCCAATCTGGGGCGTCTGGGTAAACGAGAGGCCGCCGTCTACGGCAGCGTCACCTACGCC
GAGCTGGTATCGCTCATCGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTSANPTTITVEVNPPYPVIVGTGLLGELVDNLKGSQGLAKVAILHQPTLAVTAEEIRKTLADSGIDAHRVEIPDAEAGK
DLAVLGFIWEVLGRIGIGRKDAVVSLGGGAATDTAGFAAATWLRGIKVVHVPTTLLAMVDAAVGGKTGINTEAGKNLVGA
FHQPGAVLVDLATLESLPRNEIIAGMAEVVKAGFIADPVILDLIEADPETAIDPSKPVLRELVERSIAVKATVVAADEKE
AELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELGRLAGRLDDETADRHARVLSALGLPVSYDADALGQLVEY
MQGDKKTRSGILRFVVLDGLAKPGRLEGPDPSLLAAAYSVVAGEARGEGVLL

Sequences:

>Translated_372_residues
MTSANPTTITVEVNPPYPVIVGTGLLGELVDNLKGSQGLAKVAILHQPTLAVTAEEIRKTLADSGIDAHRVEIPDAEAGK
DLAVLGFIWEVLGRIGIGRKDAVVSLGGGAATDTAGFAAATWLRGIKVVHVPTTLLAMVDAAVGGKTGINTEAGKNLVGA
FHQPGAVLVDLATLESLPRNEIIAGMAEVVKAGFIADPVILDLIEADPETAIDPSKPVLRELVERSIAVKATVVAADEKE
AELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELGRLAGRLDDETADRHARVLSALGLPVSYDADALGQLVEY
MQGDKKTRSGILRFVVLDGLAKPGRLEGPDPSLLAAAYSVVAGEARGEGVLL
>Mature_371_residues
TSANPTTITVEVNPPYPVIVGTGLLGELVDNLKGSQGLAKVAILHQPTLAVTAEEIRKTLADSGIDAHRVEIPDAEAGKD
LAVLGFIWEVLGRIGIGRKDAVVSLGGGAATDTAGFAAATWLRGIKVVHVPTTLLAMVDAAVGGKTGINTEAGKNLVGAF
HQPGAVLVDLATLESLPRNEIIAGMAEVVKAGFIADPVILDLIEADPETAIDPSKPVLRELVERSIAVKATVVAADEKEA
ELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELGRLAGRLDDETADRHARVLSALGLPVSYDADALGQLVEYM
QGDKKTRSGILRFVVLDGLAKPGRLEGPDPSLLAAAYSVVAGEARGEGVLL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=323, Percent_Identity=38.6996904024768, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320332, Length=285, Percent_Identity=38.9473684210526, Blast_Score=175, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38983; Mature: 38852

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSANPTTITVEVNPPYPVIVGTGLLGELVDNLKGSQGLAKVAILHQPTLAVTAEEIRKT
CCCCCCCEEEEEECCCCCEEECCCHHHHHHHHCCCCCCHHEEEEEECCCHHHHHHHHHHH
LADSGIDAHRVEIPDAEAGKDLAVLGFIWEVLGRIGIGRKDAVVSLGGGAATDTAGFAAA
HHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
TWLRGIKVVHVPTTLLAMVDAAVGGKTGINTEAGKNLVGAFHQPGAVLVDLATLESLPRN
HHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHCCCCCHHEEEHHHHHCCCHH
EIIAGMAEVVKAGFIADPVILDLIEADPETAIDPSKPVLRELVERSIAVKATVVAADEKE
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCHH
AELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELGRLAGRLDDETADRHARVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SALGLPVSYDADALGQLVEYMQGDKKTRSGILRFVVLDGLAKPGRLEGPDPSLLAAAYSV
HHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VAGEARGEGVLL
HHCCCCCCCCCC
>Mature Secondary Structure 
TSANPTTITVEVNPPYPVIVGTGLLGELVDNLKGSQGLAKVAILHQPTLAVTAEEIRKT
CCCCCCEEEEEECCCCCEEECCCHHHHHHHHCCCCCCHHEEEEEECCCHHHHHHHHHHH
LADSGIDAHRVEIPDAEAGKDLAVLGFIWEVLGRIGIGRKDAVVSLGGGAATDTAGFAAA
HHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
TWLRGIKVVHVPTTLLAMVDAAVGGKTGINTEAGKNLVGAFHQPGAVLVDLATLESLPRN
HHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHCCCCCHHEEEHHHHHCCCHH
EIIAGMAEVVKAGFIADPVILDLIEADPETAIDPSKPVLRELVERSIAVKATVVAADEKE
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCHH
AELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELGRLAGRLDDETADRHARVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SALGLPVSYDADALGQLVEYMQGDKKTRSGILRFVVLDGLAKPGRLEGPDPSLLAAAYSV
HHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VAGEARGEGVLL
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA