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The map label for this gene is efp

Identifier: 169629921

GI number: 169629921

Start: 2887644

End: 2888207

Strand: Reverse

Name: efp

Synonym: MAB_2837c

Alternate gene names: 169629921

Gene position: 2888207-2887644 (Counterclockwise)

Preceding gene: 169629922

Following gene: 169629920

Centisome position: 57.0

GC content: 63.12

Gene sequence:

>564_bases
GTGGCTTCAACCGCCGATTTCAAGAACGGCCTGGTGCTCAACATCGATGGTCAGCTGTGGCAGATCACCGAGTTCCAGCA
CGTGAAGCCCGGTAAGGGACCGGCCTTCGTGCGCACGAAGCTCAAGAACGTGCTCTCGGGCAAGGTCGTCGACAAGACCT
TCAACGCCGGAGTCAAGGTCGAGACCGCGACCGTCGACCGCCGCGACACCACCTACCTGTACCGCGATGGCGATTCGTTC
GTGTTCATGGACAGCCAGGACTACGAGCAGCACCATCTGTCCCCGGAGCTCGTCGGCGACGCCCATCGCTTCCTGTTGGA
GGGCATGACCGTGCAGGTCGCCTTCAACGAGGGTGCCGCGCTGTACATCGAGCTTCCGGTCTCGGTTGAGCTGGAAGTCA
CCCATACCGAACCGGGCCTGCAGGGTGATCGCTCCAGCGCGGGCACCAAGCCCGCCACGGTGGAGACCGGTGCCGAGATT
CAGGTGCCGCTGTTCATCAACACCGGTGACCGGCTGAAGGTGGATACGCGCGACGCCAGCTACCTCGGCCGTGTGAATGG
CTGA

Upstream 100 bases:

>100_bases
GACACGCTCGTGGTGCGGCCCGACGGGCCGGAGCTGTTGACCCGGTTCCCCAAGGAACTCATCGTTATCGACTGAGCAGT
GACAAGAGGAGACTGAACAC

Downstream 100 bases:

>100_bases
TATCGGTTCTCATTCGGCCCGGGCCGGCGATGAGCCGCCGGGGCGAAGAGTGTCTGGATCGGCCAAGGGGGGACGTCGCA
AGGCCCGCAAGCGGGCCGTG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MASTADFKNGLVLNIDGQLWQITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKVETATVDRRDTTYLYRDGDSF
VFMDSQDYEQHHLSPELVGDAHRFLLEGMTVQVAFNEGAALYIELPVSVELEVTHTEPGLQGDRSSAGTKPATVETGAEI
QVPLFINTGDRLKVDTRDASYLGRVNG

Sequences:

>Translated_187_residues
MASTADFKNGLVLNIDGQLWQITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKVETATVDRRDTTYLYRDGDSF
VFMDSQDYEQHHLSPELVGDAHRFLLEGMTVQVAFNEGAALYIELPVSVELEVTHTEPGLQGDRSSAGTKPATVETGAEI
QVPLFINTGDRLKVDTRDASYLGRVNG
>Mature_186_residues
ASTADFKNGLVLNIDGQLWQITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKVETATVDRRDTTYLYRDGDSFV
FMDSQDYEQHHLSPELVGDAHRFLLEGMTVQVAFNEGAALYIELPVSVELEVTHTEPGLQGDRSSAGTKPATVETGAEIQ
VPLFINTGDRLKVDTRDASYLGRVNG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=180, Percent_Identity=41.1111111111111, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=32.6315789473684, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_MYCA9 (B1MCE5)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703570.1
- ProteinModelPortal:   B1MCE5
- SMR:   B1MCE5
- EnsemblBacteria:   EBMYCT00000007466
- GeneID:   5965345
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2837c
- GeneTree:   EBGT00050000016200
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   MABS561007:MAB_2837C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20543; Mature: 20412

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTADFKNGLVLNIDGQLWQITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKV
CCCCCCCCCCEEEEECCCEEEEECEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEE
ETATVDRRDTTYLYRDGDSFVFMDSQDYEQHHLSPELVGDAHRFLLEGMTVQVAFNEGAA
EEEEECCCCCEEEEECCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCEEEEEEECCCCE
LYIELPVSVELEVTHTEPGLQGDRSSAGTKPATVETGAEIQVPLFINTGDRLKVDTRDAS
EEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCC
YLGRVNG
EEEECCC
>Mature Secondary Structure 
ASTADFKNGLVLNIDGQLWQITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKV
CCCCCCCCCEEEEECCCEEEEECEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEE
ETATVDRRDTTYLYRDGDSFVFMDSQDYEQHHLSPELVGDAHRFLLEGMTVQVAFNEGAA
EEEEECCCCCEEEEECCCEEEEECCCCCHHHCCCHHHHHHHHHHHHCCEEEEEEECCCCE
LYIELPVSVELEVTHTEPGLQGDRSSAGTKPATVETGAEIQVPLFINTGDRLKVDTRDAS
EEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCC
YLGRVNG
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA