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The map label for this gene is pyrR [H]

Identifier: 169629916

GI number: 169629916

Start: 2883979

End: 2884527

Strand: Reverse

Name: pyrR [H]

Synonym: MAB_2832c

Alternate gene names: 169629916

Gene position: 2884527-2883979 (Counterclockwise)

Preceding gene: 169629918

Following gene: 169629915

Centisome position: 56.93

GC content: 67.03

Gene sequence:

>549_bases
TTGCTGTCCGCCGCAGATGTCGGCAGGACCATCTCGCGTATCGCGCATCAAATCATCGAAAAGACCGCGCTTTCTGACTC
CGGTGACGCGCCCCGCGTCGTCTTGGTCGGCATCCCTACCCGCGGAGCCACCCTCGCCAAGCGGCTCGCCGCACACATCA
CCGAATTCTCCGGTGTCGAGGTGCCCGCGGGATTCTTGGACATCACGCTGTACCGCGACGACCTGCGCAACAAACCACAC
CGCCCGCTCGAACGCACCTCCATTCCCGAGGGTGGCGTCGATGGCGCTCTGGTGGTGCTGGTCGACGACGTGCTGTTCTC
CGGCCGTACCGTGCGCTCGGCACTTGACGCGCTGCGGGACCTCGGCAGGCCGCGTGCGGTGCAGCTGGCGGTGCTGGTCG
ACCGCGGACATCGCGAGCTGCCGCTGCGTGCGGATTACGTCGGCAAGAACGTGCCGACGGCACGCTCGGAGGACGTCAAG
GTGCTGCTGGCCGAACACGACGGCCGCGACGCGGTGATCATCACGAGCGGGCAAGGGGCGCAGACATGA

Upstream 100 bases:

>100_bases
GATCCGTCCAGTGAGGCGGAGAAGGAGGTCTCGCGTAAGCGTGGGCGCATCATCTGACTCGGAGCCGCAATGTCGGCGAC
ATCCGGTTGAAGGACGCGAA

Downstream 100 bases:

>100_bases
GACATCTCCTCTCCGCGGCCGACCTCACGCGTGACGAGGCCACCGCCATCCTCGACGACGCCGACCGGTTCCTGCAGGCG
CTAGCCGGGCGTGAGGTCAA

Product: PyrR bifunctional protein (pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase)

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MLSAADVGRTISRIAHQIIEKTALSDSGDAPRVVLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLYRDDLRNKPH
RPLERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTARSEDVK
VLLAEHDGRDAVIITSGQGAQT

Sequences:

>Translated_182_residues
MLSAADVGRTISRIAHQIIEKTALSDSGDAPRVVLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLYRDDLRNKPH
RPLERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTARSEDVK
VLLAEHDGRDAVIITSGQGAQT
>Mature_182_residues
MLSAADVGRTISRIAHQIIEKTALSDSGDAPRVVLVGIPTRGATLAKRLAAHITEFSGVEVPAGFLDITLYRDDLRNKPH
RPLERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRDLGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTARSEDVK
VLLAEHDGRDAVIITSGQGAQT

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 19509; Mature: 19509

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAADVGRTISRIAHQIIEKTALSDSGDAPRVVLVGIPTRGATLAKRLAAHITEFSGVE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCC
VPAGFLDITLYRDDLRNKPHRPLERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRD
CCCCEEEEEEEHHHHCCCCCCCCHHCCCCCCCCCCEEEEEEEHHHHCCHHHHHHHHHHHH
LGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTARSEDVKVLLAEHDGRDAVIITSGQGA
CCCCCEEEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCC
QT
CC
>Mature Secondary Structure
MLSAADVGRTISRIAHQIIEKTALSDSGDAPRVVLVGIPTRGATLAKRLAAHITEFSGVE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCC
VPAGFLDITLYRDDLRNKPHRPLERTSIPEGGVDGALVVLVDDVLFSGRTVRSALDALRD
CCCCEEEEEEEHHHHCCCCCCCCHHCCCCCCCCCCEEEEEEEHHHHCCHHHHHHHHHHHH
LGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTARSEDVKVLLAEHDGRDAVIITSGQGA
CCCCCEEEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCC
QT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA