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The map label for this gene is argK [C]

Identifier: 169629794

GI number: 169629794

Start: 2756385

End: 2757356

Strand: Reverse

Name: argK [C]

Synonym: MAB_2710c

Alternate gene names: 169629794

Gene position: 2757356-2756385 (Counterclockwise)

Preceding gene: 169629795

Following gene: 169629793

Centisome position: 54.42

GC content: 65.33

Gene sequence:

>972_bases
ATGTCGGCACCTGACAATCTGGCAGCACTGATCCGGTCGGGAGACCGTTCCGGCCTGGCCCGGGCCATCACCTTGGTGGA
GTCGACCCGACAAGATCACCGGTCGCAGGCGCAGCAGTTGCTGCTCGAGCTCTCGCCCGAGGGGGGAAACGCACTGCGCG
TGGGGATTACCGGAGTGCCCGGGGTGGGGAAGTCGACCACCATCGAGGCGCTCGGGATGTATCTCATCGAACAGGGACAT
CGCGTCGCCGTGCTGGCGGTCGACCCATCGTCGACGCGCACCGGCGGATCGATCCTGGGGGACAAGACCCGGATGGGTCG
GCTCTCGGTGCATCCGGATGCCTACATCCGGCCGTCGCCGACCTCGGGAACCCTGGGTGGGGTGGCCAAGGCCACCCGTG
AGACGGTGGTCCTGCTGGAGGCCGCCGGCTTCGATGTCATCCTGATCGAGACTGTGGGCGTGGGGCAGTCCGAGGTCGCG
GTCGCCAATATGGTCGACACATTTGTCTTCCTGACGTTGGCGCGCACCGGCGACCAGTTGCAGGGAATCAAGAAGGGCGT
ACTCGAACTCGCCGATATCGTGGTGGTGAACAAGGCCGATGGTGAGCACGCCATCGAAGCCAAGAAGGCCGCCCGTGAAT
TGTCGGGAGCCTTGCGCCTGATCTATCCGCATGACACGCTCTGGCGCCCACCGGTTCTCACCATGAGTGCGCTGGAGAAC
AACGGTGTCTCCGAGATGTGGGACACGGTGCTGCAGCATCGCGCGGTGCTCACCGAAGCGGGCGAGTTCGAGGCCAAACG
CCGCCGCCAGCAAGTCGATTGGATGTGGGCGATGGTGCGCGACGCGGTGCTCGACCGGGTTTTGAACGCCCCCGACGTGA
AGGCGTCGCGTGCTGATATCGAGCAGCAGGTGCGGGAAGGCACCCTGACGCCCGCGCTGGCCGCCGAGCAACTACTCAAC
CTCAGCTCGTAG

Upstream 100 bases:

>100_bases
CGGGCGCCGCGGCCATCTTCCCTCCCGGAACGGTGATCTCGGAGGCCGCAATTGGCCTGTTGCACAAGCTGGCTGAGCGG
CTCGGGTACGACCTGACCTG

Downstream 100 bases:

>100_bases
ACCTCGAGCGCGGCGTTGCGCACACAAACACGCCGGTATGTGTGTGCCCAAGGTGTCGCCCGCGAGAAGATGTCTGGATG
GCGTTGGTTTTTCTCGATAC

Product: putative kinase ArgK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSAPDNLAALIRSGDRSGLARAITLVESTRQDHRSQAQQLLLELSPEGGNALRVGITGVPGVGKSTTIEALGMYLIEQGH
RVAVLAVDPSSTRTGGSILGDKTRMGRLSVHPDAYIRPSPTSGTLGGVAKATRETVVLLEAAGFDVILIETVGVGQSEVA
VANMVDTFVFLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKKAARELSGALRLIYPHDTLWRPPVLTMSALEN
NGVSEMWDTVLQHRAVLTEAGEFEAKRRRQQVDWMWAMVRDAVLDRVLNAPDVKASRADIEQQVREGTLTPALAAEQLLN
LSS

Sequences:

>Translated_323_residues
MSAPDNLAALIRSGDRSGLARAITLVESTRQDHRSQAQQLLLELSPEGGNALRVGITGVPGVGKSTTIEALGMYLIEQGH
RVAVLAVDPSSTRTGGSILGDKTRMGRLSVHPDAYIRPSPTSGTLGGVAKATRETVVLLEAAGFDVILIETVGVGQSEVA
VANMVDTFVFLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKKAARELSGALRLIYPHDTLWRPPVLTMSALEN
NGVSEMWDTVLQHRAVLTEAGEFEAKRRRQQVDWMWAMVRDAVLDRVLNAPDVKASRADIEQQVREGTLTPALAAEQLLN
LSS
>Mature_322_residues
SAPDNLAALIRSGDRSGLARAITLVESTRQDHRSQAQQLLLELSPEGGNALRVGITGVPGVGKSTTIEALGMYLIEQGHR
VAVLAVDPSSTRTGGSILGDKTRMGRLSVHPDAYIRPSPTSGTLGGVAKATRETVVLLEAAGFDVILIETVGVGQSEVAV
ANMVDTFVFLTLARTGDQLQGIKKGVLELADIVVVNKADGEHAIEAKKAARELSGALRLIYPHDTLWRPPVLTMSALENN
GVSEMWDTVLQHRAVLTEAGEFEAKRRRQQVDWMWAMVRDAVLDRVLNAPDVKASRADIEQQVREGTLTPALAAEQLLNL
SS

Specific function: Probable GTPase. May also bind and hydrolyze ATP. May function as chaperone (Probable) [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=326, Percent_Identity=48.4662576687117, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1789285, Length=308, Percent_Identity=46.1038961038961, Blast_Score=276, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71994271, Length=318, Percent_Identity=43.7106918238994, Blast_Score=265, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71994275, Length=269, Percent_Identity=44.9814126394052, Blast_Score=249, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34649; Mature: 34518

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPDNLAALIRSGDRSGLARAITLVESTRQDHRSQAQQLLLELSPEGGNALRVGITGVP
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GVGKSTTIEALGMYLIEQGHRVAVLAVDPSSTRTGGSILGDKTRMGRLSVHPDAYIRPSP
CCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
TSGTLGGVAKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFVFLTLARTGDQL
CCCCCHHHHHHHHCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHH
QGIKKGVLELADIVVVNKADGEHAIEAKKAARELSGALRLIYPHDTLWRPPVLTMSALEN
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHCC
NGVSEMWDTVLQHRAVLTEAGEFEAKRRRQQVDWMWAMVRDAVLDRVLNAPDVKASRADI
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EQQVREGTLTPALAAEQLLNLSS
HHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SAPDNLAALIRSGDRSGLARAITLVESTRQDHRSQAQQLLLELSPEGGNALRVGITGVP
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GVGKSTTIEALGMYLIEQGHRVAVLAVDPSSTRTGGSILGDKTRMGRLSVHPDAYIRPSP
CCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
TSGTLGGVAKATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFVFLTLARTGDQL
CCCCCHHHHHHHHCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHH
QGIKKGVLELADIVVVNKADGEHAIEAKKAARELSGALRLIYPHDTLWRPPVLTMSALEN
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHCC
NGVSEMWDTVLQHRAVLTEAGEFEAKRRRQQVDWMWAMVRDAVLDRVLNAPDVKASRADI
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
EQQVREGTLTPALAAEQLLNLSS
HHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]