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The map label for this gene is lspA [H]

Identifier: 169629785

GI number: 169629785

Start: 2745355

End: 2745942

Strand: Reverse

Name: lspA [H]

Synonym: MAB_2700c

Alternate gene names: 169629785

Gene position: 2745942-2745355 (Counterclockwise)

Preceding gene: 169629787

Following gene: 169629784

Centisome position: 54.19

GC content: 64.8

Gene sequence:

>588_bases
GTGAGTGACGAGTCCGAGACCGCCCGGAAGCCAAAGCGGCGGATAAAACTGCTGCTCATCGTGGCGTCGGTGGTGCTCGT
ACTGGACGTCGTGACCAAGGTTCTCGCCGTCAGGCTGCTACAACCCGGCAAGCCGGTGCCCATCATCGGCGACACCGTCA
CCTGGACGCTGGTGCGCAATTCGGGCGCCGCGTTCTCGTTCGCCACGGGCTATACCTGGGTGCTCACCCTCATCGCCATC
TCGGTGGTGGTGGGAATCCTGTTCATCGGTCGTCGGTTGGTCTCGACGTGGTGGGCAATCGGCTTGGGCATGATTCTCGG
CGGTGCACTGGGCAATCTCGTGGACAGGTTCTTCCGCGGCCCGGGACCGCTGCGCGGCCACGTGGTGGACTTCCTGTCCG
TGGGGTGGTGGCCGGTCTTCAATGTCGCGGACCCCTCCGTGGTGGGTGGCGCGATTCTGCTGGTGGCACTGTCGCTGTTC
GGTTACGACTACGACCGCGAGGGCCGTTCTACCTCGAAACCAGCGAGCAGTGGCCCGGAGGACAGCGTGAACGCGGACCC
GCAGGCTTCCCAGACCAAGCCGTCATGA

Upstream 100 bases:

>100_bases
GCTGGCGAGGAGTCATTTGGGCGAAGAGCGGCAGGCACAGCGGCGATCATCGCAGACAGGTTGCGCAAAGCGCTGCGCCG
CGTAAGGGATGATGGGGGAC

Downstream 100 bases:

>100_bases
CGTCGCGCTCTCTGCCGGTTCCGGACGGCCTGTCCGGTATGCGTGTGGACGCAGGTTTGGCTCGTCTGCTGGGACTTTCG
CGCACCGCCGCGGCCGCCCT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSDESETARKPKRRIKLLLIVASVVLVLDVVTKVLAVRLLQPGKPVPIIGDTVTWTLVRNSGAAFSFATGYTWVLTLIAI
SVVVGILFIGRRLVSTWWAIGLGMILGGALGNLVDRFFRGPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVALSLF
GYDYDREGRSTSKPASSGPEDSVNADPQASQTKPS

Sequences:

>Translated_195_residues
MSDESETARKPKRRIKLLLIVASVVLVLDVVTKVLAVRLLQPGKPVPIIGDTVTWTLVRNSGAAFSFATGYTWVLTLIAI
SVVVGILFIGRRLVSTWWAIGLGMILGGALGNLVDRFFRGPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVALSLF
GYDYDREGRSTSKPASSGPEDSVNADPQASQTKPS
>Mature_194_residues
SDESETARKPKRRIKLLLIVASVVLVLDVVTKVLAVRLLQPGKPVPIIGDTVTWTLVRNSGAAFSFATGYTWVLTLIAIS
VVVGILFIGRRLVSTWWAIGLGMILGGALGNLVDRFFRGPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVALSLFG
YDYDREGRSTSKPASSGPEDSVNADPQASQTKPS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 20872; Mature: 20740

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDESETARKPKRRIKLLLIVASVVLVLDVVTKVLAVRLLQPGKPVPIIGDTVTWTLVRN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEEEEC
SGAAFSFATGYTWVLTLIAISVVVGILFIGRRLVSTWWAIGLGMILGGALGNLVDRFFRG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVALSLFGYDYDREGRSTSKPASSGPE
CCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DSVNADPQASQTKPS
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDESETARKPKRRIKLLLIVASVVLVLDVVTKVLAVRLLQPGKPVPIIGDTVTWTLVRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEEEEC
SGAAFSFATGYTWVLTLIAISVVVGILFIGRRLVSTWWAIGLGMILGGALGNLVDRFFRG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVALSLFGYDYDREGRSTSKPASSGPE
CCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DSVNADPQASQTKPS
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]