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The map label for this gene is dinB1 [H]

Identifier: 169629787

GI number: 169629787

Start: 2746923

End: 2748302

Strand: Reverse

Name: dinB1 [H]

Synonym: MAB_2702c

Alternate gene names: 169629787

Gene position: 2748302-2746923 (Counterclockwise)

Preceding gene: 169629789

Following gene: 169629785

Centisome position: 54.24

GC content: 65.87

Gene sequence:

>1380_bases
GTGTGTGCTGCCGGTCGATGGGTTTTGCACCTCGACATGGACGCCTTCTTCGCTTCGGTCGAGCAGCTGACCCGGCCCAC
CCTGCGTGGTCGTCCGGTACTCGTCGGCGGCACCGGCGGCCGCGGCGTGGTGGCCGGCGCGAGCTACGAGGCCAGGGTCT
TCGGGGCCCGTTCGGCCATGCCGATGCATCAGGCTCGGCGCCTGGTGGGCATCAACGCTGTCGTCTTGCCGCCTCGCGGT
TCGGTGTACGGCGTGGCCAGCAGGCGCGTATTCGAGACAGTGCGATCGATGATCCCCATTCTGGAGCAGCTGTCGTTCGA
TGAGGCGTTTGGAGAACCGTCCGAATTATTCGGTGCCACAACAAGTGCAGTCGCGGATTACATTCATGAGTTGCGTTCAC
GCGTGCTCGGCGAGACCGGTCTCACCGCGTCGGTAGGGGCGGGCTCGGGTAAACAGATTGCCAAGATCGCCTCGGGGTTG
GCCAAGCCCGACGGCGTGCGGATCATAGCGCCGGAGGAAGAACGGACACTGCTCGACGAGCTCCCGGTGCGCAAATTGTG
GGGTATCGGCCCGGTCGCCGAAGAGCGCCTGAATAGGTTGGGTATCAACACAATTGGCCAGTTCGCGGCCCTGCAGACCA
GTGAGGCGGCCTCGGTCTTGGGTGGCACGATCGGCCCCGCGCTGCACCAGCTGGCCCGTGGCGTCGATGACCGCCCGGTG
GCCGAGCGGGCCGAAACCAAACAGATCAGCGCGGAATCGACGTTTCCCGACGACCTGACAACCCTTGATCAACTACGCCA
GGCCATCGAGCCCATCGGTGTCCACGCCCACCGGCGACTCATCAAACACGGGCGTGGCGTCCGGACCGTCACCGTGAAGT
TGCGGCGCTCGGATATGAGCATCCTGACCAGGTCCGCGACGCTGCCCTACGCCACCACGGAACGCGCGGTACTGATGTCG
GCGGCGCGCCGGCTGCTGCTGGATCCCGTCGAGATCGGGCCGATCCGTCTTGTCGGCGTAGGTTTTTCGGGATTCTCCGA
TGTTCAGCAGACCTCGTTGTTCCCGGATCTGGATCAGGCCGAGCCCGTTGCCGAGTCCGACGAGGTGCCATCTACCGCGG
AGCCCACCCACAGCACGGCTGGTTGGGGTGTCGGGGATGACGTCGACCACGCCGAGTTCGGGCACGGGTGGATACAGGGC
ACCGGGCACGGTGTCATGACGGTGAGATTTGAGACGCGAAGCAGCGGTCCGGGTATCGCGCGCACCTTCGCGGTCGATGA
TCCGGGTATCGCGCGCGCCGACCCGGTGGCGAGCCTGGACTGGCCGGGGGAGTCAGCCGAGCCGGTCGATGACGGCGACG
AGATCGGAACCGGTGGCTAG

Upstream 100 bases:

>100_bases
GAGGGCTGCGGGCCAGCGGCTACCGGGATTCGGCCAATCCATATCGAGCTTCCGACAGCGATACCCGTGGGCAGTCGGTG
GGCCGCAATACGATGGGCGC

Downstream 100 bases:

>100_bases
GGCCGCCATCAACAGCACTCGCGCTTGGCCGGCGCGAAGCCGAGGCGCGACCACCGCGCCGGCGTCGATGAGCTTCTGTC
CCGGTGCGTAGCCCGGGGAC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MCAAGRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGTGGRGVVAGASYEARVFGARSAMPMHQARRLVGINAVVLPPRG
SVYGVASRRVFETVRSMIPILEQLSFDEAFGEPSELFGATTSAVADYIHELRSRVLGETGLTASVGAGSGKQIAKIASGL
AKPDGVRIIAPEEERTLLDELPVRKLWGIGPVAEERLNRLGINTIGQFAALQTSEAASVLGGTIGPALHQLARGVDDRPV
AERAETKQISAESTFPDDLTTLDQLRQAIEPIGVHAHRRLIKHGRGVRTVTVKLRRSDMSILTRSATLPYATTERAVLMS
AARRLLLDPVEIGPIRLVGVGFSGFSDVQQTSLFPDLDQAEPVAESDEVPSTAEPTHSTAGWGVGDDVDHAEFGHGWIQG
TGHGVMTVRFETRSSGPGIARTFAVDDPGIARADPVASLDWPGESAEPVDDGDEIGTGG

Sequences:

>Translated_459_residues
MCAAGRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGTGGRGVVAGASYEARVFGARSAMPMHQARRLVGINAVVLPPRG
SVYGVASRRVFETVRSMIPILEQLSFDEAFGEPSELFGATTSAVADYIHELRSRVLGETGLTASVGAGSGKQIAKIASGL
AKPDGVRIIAPEEERTLLDELPVRKLWGIGPVAEERLNRLGINTIGQFAALQTSEAASVLGGTIGPALHQLARGVDDRPV
AERAETKQISAESTFPDDLTTLDQLRQAIEPIGVHAHRRLIKHGRGVRTVTVKLRRSDMSILTRSATLPYATTERAVLMS
AARRLLLDPVEIGPIRLVGVGFSGFSDVQQTSLFPDLDQAEPVAESDEVPSTAEPTHSTAGWGVGDDVDHAEFGHGWIQG
TGHGVMTVRFETRSSGPGIARTFAVDDPGIARADPVASLDWPGESAEPVDDGDEIGTGG
>Mature_459_residues
MCAAGRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGTGGRGVVAGASYEARVFGARSAMPMHQARRLVGINAVVLPPRG
SVYGVASRRVFETVRSMIPILEQLSFDEAFGEPSELFGATTSAVADYIHELRSRVLGETGLTASVGAGSGKQIAKIASGL
AKPDGVRIIAPEEERTLLDELPVRKLWGIGPVAEERLNRLGINTIGQFAALQTSEAASVLGGTIGPALHQLARGVDDRPV
AERAETKQISAESTFPDDLTTLDQLRQAIEPIGVHAHRRLIKHGRGVRTVTVKLRRSDMSILTRSATLPYATTERAVLMS
AARRLLLDPVEIGPIRLVGVGFSGFSDVQQTSLFPDLDQAEPVAESDEVPSTAEPTHSTAGWGVGDDVDHAEFGHGWIQG
TGHGVMTVRFETRSSGPGIARTFAVDDPGIARADPVASLDWPGESAEPVDDGDEIGTGG

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=431, Percent_Identity=26.2180974477958, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI7706681, Length=432, Percent_Identity=26.1574074074074, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI154350220, Length=332, Percent_Identity=25.3012048192771, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7705344, Length=254, Percent_Identity=26.3779527559055, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI5729982, Length=158, Percent_Identity=27.8481012658228, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786425, Length=324, Percent_Identity=33.0246913580247, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787432, Length=325, Percent_Identity=28.6153846153846, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17537959, Length=325, Percent_Identity=26.4615384615385, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193205702, Length=221, Percent_Identity=32.579185520362, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193205700, Length=221, Percent_Identity=32.579185520362, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=321, Percent_Identity=23.3644859813084, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=401, Percent_Identity=26.1845386533666, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24668444, Length=371, Percent_Identity=24.7978436657682, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355641, Length=289, Percent_Identity=24.2214532871972, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644984, Length=289, Percent_Identity=24.2214532871972, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 48763; Mature: 48763

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAAGRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGTGGRGVVAGASYEARVFGARSAM
CCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCCEEEECCCCCC
PMHQARRLVGINAVVLPPRGSVYGVASRRVFETVRSMIPILEQLSFDEAFGEPSELFGAT
CHHHHHHHHCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHCCH
TSAVADYIHELRSRVLGETGLTASVGAGSGKQIAKIASGLAKPDGVRIIAPEEERTLLDE
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
LPVRKLWGIGPVAEERLNRLGINTIGQFAALQTSEAASVLGGTIGPALHQLARGVDDRPV
CCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCH
AERAETKQISAESTFPDDLTTLDQLRQAIEPIGVHAHRRLIKHGRGVRTVTVKLRRSDMS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEEEECCCHH
ILTRSATLPYATTERAVLMSAARRLLLDPVEIGPIRLVGVGFSGFSDVQQTSLFPDLDQA
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCC
EPVAESDEVPSTAEPTHSTAGWGVGDDVDHAEFGHGWIQGTGHGVMTVRFETRSSGPGIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEECCCEEEEEEEECCCCCCCCE
RTFAVDDPGIARADPVASLDWPGESAEPVDDGDEIGTGG
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCAAGRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGTGGRGVVAGASYEARVFGARSAM
CCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCCEEEECCCCCC
PMHQARRLVGINAVVLPPRGSVYGVASRRVFETVRSMIPILEQLSFDEAFGEPSELFGAT
CHHHHHHHHCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHCCH
TSAVADYIHELRSRVLGETGLTASVGAGSGKQIAKIASGLAKPDGVRIIAPEEERTLLDE
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
LPVRKLWGIGPVAEERLNRLGINTIGQFAALQTSEAASVLGGTIGPALHQLARGVDDRPV
CCHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCH
AERAETKQISAESTFPDDLTTLDQLRQAIEPIGVHAHRRLIKHGRGVRTVTVKLRRSDMS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEEEECCCHH
ILTRSATLPYATTERAVLMSAARRLLLDPVEIGPIRLVGVGFSGFSDVQQTSLFPDLDQA
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCC
EPVAESDEVPSTAEPTHSTAGWGVGDDVDHAEFGHGWIQGTGHGVMTVRFETRSSGPGIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEECCCEEEEEEEECCCCCCCCE
RTFAVDDPGIARADPVASLDWPGESAEPVDDGDEIGTGG
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]