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The map label for this gene is mmpL4 [H]

Identifier: 169629735

GI number: 169629735

Start: 2690414

End: 2693233

Strand: Direct

Name: mmpL4 [H]

Synonym: MAB_2650

Alternate gene names: 169629735

Gene position: 2690414-2693233 (Clockwise)

Preceding gene: 169629734

Following gene: 169629739

Centisome position: 53.09

GC content: 60.5

Gene sequence:

>2820_bases
ATGAGCGCACACTCCGCACAGAAATCATTGTTCGCCAGAATGATTCGGAAGTATTCGATACTTGTGGTGCTGGCGTGGGT
CGCGTTCACCGTCGTGATCAATGTGGTGGTGCCGCAGCTCGAACCGGTGACCGACGCCAATCAGGGGCCGCTGGTACCGC
TCGACGCGCCGTCCTCCAAGGCGCTCATTCACATTGGTGAATCGTTCCAGGAGTCCGACAGCAACAGCCTGGCCATGGTC
ATCCTGGAGGGTGATCACAAGCTGAACGACGCCGACCACAAGTTCTACGACGTGCTGGCAAGCAAGCTGGAAAACGATAA
GAAGCACGTTCAATACGTGATGAATCTGTGGGGCCAGGGAACCACCGCGGCAGGCGTGCAGAGCTCCGACGGCCAGGCGG
CCTACACGCTCGTGCGCGTCGCCGGCGATCAAGGGTCTACGGTCTCAGACGAGTCCATTCGCGCTGTGCGCGAGCTGGTC
GCCGAGGTCCAGCCCCCTAACGGGGTCAAGGTTTATGTCTCCGGGTCGGCCCCGTTGTCCACGGACATGCTGCAGGTGGG
TAACCAGAGCATGATCCGCCTGATGTACGTGACCATCGTGATCATCACGGTGATGCTGCTCATCGTCTACCGGTCATTCA
CGACGGCATTCCTGACGCTGCTGATCGTGATGGTAGAATTGTCTTGTGGTCGAGGAGTTGTCGCATTCCTGGCCTATCAC
AAGCTCATTGGCATCTCGGTGTTCGCGTCGAACATCCTGGTGTCGCTGATCCTGGGGGCCGGCACCGATTACGCGATCTT
CCTGATCGGAAGGTATCAAGAGGCGCGTCATGCCGGCGAAGACCGCGAGACTGCGTACTACTCCGCGGTCAAGGGCGTCT
CCCACGTCATCCTCGGTTCCGGGCTGGCTATCGCGGGTGCAACCTTCTGCCTGCAGTTCACGCGCCTGAACTACTTCAAC
ACCATGGGCCTGCCCTGTGCGGCGGCAACACTCGTCGCTGTCGCCGCCTCCCTCACCTTTGGGCCCGCAGTGTTGGCCCT
GGGTAGCCGCTTTGGGATCTTTGACCCGAAAAGGAAAGCGGACTCGGGTATTTGGCGCAAGGTGGGTACCGTCACCGTGC
GGTGGCCCGGACGCATTCTCGTGGTGAGCAGCGTGGTGGTGATGATCGGTTCGATCACCCTTCCGACATACAAGCCCAAC
TACAACGACAGGATCTACATCGCCGGCGATGTACCGGCGAATCAGGGCTACGCGGCGGCGGACCGGCATTTTCCGGTGAG
CAAGCTCAACAGCGACATGCTGATGGTCGAATCCGACCACGATATGCGTAATTCCACGGACATGATCGCCCTGGACAAGG
TGGCGCGTGAGGTCTTCCACACGCCCGGCGTTGCGATGATCCAAAGTGTCACCCGCCCGTTAGGCACACCGCTGGAGCAT
TCATCGTTCACGTACACGATGGGCACGATGGGCACCAAAATCAACGAAATACTGCCCTTCCTTACCGATCTCACCGATCG
GTTCACCCAAATGGCCGATATCACCGACCGGATGGCCGCGCTGATGCGCCAACAGCAAGGGCTCACCGGGCAGCAGGCAG
GGGCATCGCATATCTCACTCAAGGGTGCCCAAGAGCTGAAGGATGTCACGGTCACCATGCGCGACACCCTGGCCAACTTC
GATGACCAATTCCGGCCGCTGCGCAACTATTTCTACTGGGAGCCCCATTGCGCGGACATCCCGATGTGCTGGGCCATGCG
ATCGCTGTTCGACATGACCGACCAGGTCGATTCGATGACCGACGCGGTGGACGACAGCCTCAAGGCCGCGGTGATCCAGG
ACGCGGTCACTCCCCAACTGGTGGAGGTGATCGGCAAGAGTGCTGCCGAACTGGACAACATGAGAAAGGTGGTACTCACC
GAACAGAGCACCATGCGGCCGATGCTCACCCAGATGAATGAGCTGGGCCGCCAAATGATGGATCTCGGATACGCATTCGA
CAGTTCGAAGAACGACGAGTTCTTCTACCTGCCGCCCGATGCGTTCGACAACCCGTACTTCCAGATCGACCTCAAGTACT
TCGTATCCCCCGACGGAAAATCCGCCCGCTACATGATCTATCACGACGGGGAGGCGCTGAGCACGGAAGGAATTGACCAT
GCGCAGGCATACCTGCCCAAGGCCAAGGAGGCCCTGAAGGGAACCACGCTAGCCGGATCACGGGTCTACCTAGGCGGCGC
CGCGGCGACCTACTGGGACATCCAAGACGCCACCAAGACCGATCTGCTGATCGCCGCGATCGCCGCATTCGCCCTGATTT
TCCTGGTGATGCTGGTGATCACCAGAAGTGTGGTGGCAGCGCTGGTCATCGTCGGCACGGTGGCGTTCTCGTACTCCGGC
GCGTTCGGCCTATCGGTACTGGTCTGGCAGCACTTCCTCGGCATACCGCTGAGCTGGCTGAACCTGCCCATCACCTTCAT
CATCCTGGTCGCGGTGGGATCGGACTACAACCTACTGCTGATCTCCCGCTACCTGGAGGAAAGCAAAGCCGGGCTCAACA
CTGGCCTGATCCGGGCGGTGGCAAACTCCGGTAAGGTGGTGACCACCGCAGGCATCGTGTTCGCAACGACCATGATGGCC
ATGCTCTCCAGCGACCTGCTGTCGGTGGGCCAGCTGGGCTCCATCATCGGGTTAGGCCTGCTGTTGGACACCCTGATCGT
GCGCTCGTTCATCACACCCGCGATCGCACGGCTCCTCGGCCCGCTGTTCTGGTGGCCCCGGCTGATCCGTTCGCGCCCGG
CGCCCGCACAATACCGGTGA

Upstream 100 bases:

>100_bases
GCGGAAATGTCGGCTGCCGGATCACCGTTGACGGCTTGGTCCGCTCGGAGCACACCGCCACCGGTGAGCACGCGGGCGTC
TGGTGCCAGGTGCTGTCGGC

Downstream 100 bases:

>100_bases
ATTAAGTCGACTATTAATCGATTTCACGCGGCGAAGCAGGTTCCAATGGAGTGCCCAGACCGTGCCACCTAGCGGGAACA
GAGCCCTGGCCCAAGGAAAC

Product: MmpL family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 939; Mature: 938

Protein sequence:

>939_residues
MSAHSAQKSLFARMIRKYSILVVLAWVAFTVVINVVVPQLEPVTDANQGPLVPLDAPSSKALIHIGESFQESDSNSLAMV
ILEGDHKLNDADHKFYDVLASKLENDKKHVQYVMNLWGQGTTAAGVQSSDGQAAYTLVRVAGDQGSTVSDESIRAVRELV
AEVQPPNGVKVYVSGSAPLSTDMLQVGNQSMIRLMYVTIVIITVMLLIVYRSFTTAFLTLLIVMVELSCGRGVVAFLAYH
KLIGISVFASNILVSLILGAGTDYAIFLIGRYQEARHAGEDRETAYYSAVKGVSHVILGSGLAIAGATFCLQFTRLNYFN
TMGLPCAAATLVAVAASLTFGPAVLALGSRFGIFDPKRKADSGIWRKVGTVTVRWPGRILVVSSVVVMIGSITLPTYKPN
YNDRIYIAGDVPANQGYAAADRHFPVSKLNSDMLMVESDHDMRNSTDMIALDKVAREVFHTPGVAMIQSVTRPLGTPLEH
SSFTYTMGTMGTKINEILPFLTDLTDRFTQMADITDRMAALMRQQQGLTGQQAGASHISLKGAQELKDVTVTMRDTLANF
DDQFRPLRNYFYWEPHCADIPMCWAMRSLFDMTDQVDSMTDAVDDSLKAAVIQDAVTPQLVEVIGKSAAELDNMRKVVLT
EQSTMRPMLTQMNELGRQMMDLGYAFDSSKNDEFFYLPPDAFDNPYFQIDLKYFVSPDGKSARYMIYHDGEALSTEGIDH
AQAYLPKAKEALKGTTLAGSRVYLGGAAATYWDIQDATKTDLLIAAIAAFALIFLVMLVITRSVVAALVIVGTVAFSYSG
AFGLSVLVWQHFLGIPLSWLNLPITFIILVAVGSDYNLLLISRYLEESKAGLNTGLIRAVANSGKVVTTAGIVFATTMMA
MLSSDLLSVGQLGSIIGLGLLLDTLIVRSFITPAIARLLGPLFWWPRLIRSRPAPAQYR

Sequences:

>Translated_939_residues
MSAHSAQKSLFARMIRKYSILVVLAWVAFTVVINVVVPQLEPVTDANQGPLVPLDAPSSKALIHIGESFQESDSNSLAMV
ILEGDHKLNDADHKFYDVLASKLENDKKHVQYVMNLWGQGTTAAGVQSSDGQAAYTLVRVAGDQGSTVSDESIRAVRELV
AEVQPPNGVKVYVSGSAPLSTDMLQVGNQSMIRLMYVTIVIITVMLLIVYRSFTTAFLTLLIVMVELSCGRGVVAFLAYH
KLIGISVFASNILVSLILGAGTDYAIFLIGRYQEARHAGEDRETAYYSAVKGVSHVILGSGLAIAGATFCLQFTRLNYFN
TMGLPCAAATLVAVAASLTFGPAVLALGSRFGIFDPKRKADSGIWRKVGTVTVRWPGRILVVSSVVVMIGSITLPTYKPN
YNDRIYIAGDVPANQGYAAADRHFPVSKLNSDMLMVESDHDMRNSTDMIALDKVAREVFHTPGVAMIQSVTRPLGTPLEH
SSFTYTMGTMGTKINEILPFLTDLTDRFTQMADITDRMAALMRQQQGLTGQQAGASHISLKGAQELKDVTVTMRDTLANF
DDQFRPLRNYFYWEPHCADIPMCWAMRSLFDMTDQVDSMTDAVDDSLKAAVIQDAVTPQLVEVIGKSAAELDNMRKVVLT
EQSTMRPMLTQMNELGRQMMDLGYAFDSSKNDEFFYLPPDAFDNPYFQIDLKYFVSPDGKSARYMIYHDGEALSTEGIDH
AQAYLPKAKEALKGTTLAGSRVYLGGAAATYWDIQDATKTDLLIAAIAAFALIFLVMLVITRSVVAALVIVGTVAFSYSG
AFGLSVLVWQHFLGIPLSWLNLPITFIILVAVGSDYNLLLISRYLEESKAGLNTGLIRAVANSGKVVTTAGIVFATTMMA
MLSSDLLSVGQLGSIIGLGLLLDTLIVRSFITPAIARLLGPLFWWPRLIRSRPAPAQYR
>Mature_938_residues
SAHSAQKSLFARMIRKYSILVVLAWVAFTVVINVVVPQLEPVTDANQGPLVPLDAPSSKALIHIGESFQESDSNSLAMVI
LEGDHKLNDADHKFYDVLASKLENDKKHVQYVMNLWGQGTTAAGVQSSDGQAAYTLVRVAGDQGSTVSDESIRAVRELVA
EVQPPNGVKVYVSGSAPLSTDMLQVGNQSMIRLMYVTIVIITVMLLIVYRSFTTAFLTLLIVMVELSCGRGVVAFLAYHK
LIGISVFASNILVSLILGAGTDYAIFLIGRYQEARHAGEDRETAYYSAVKGVSHVILGSGLAIAGATFCLQFTRLNYFNT
MGLPCAAATLVAVAASLTFGPAVLALGSRFGIFDPKRKADSGIWRKVGTVTVRWPGRILVVSSVVVMIGSITLPTYKPNY
NDRIYIAGDVPANQGYAAADRHFPVSKLNSDMLMVESDHDMRNSTDMIALDKVAREVFHTPGVAMIQSVTRPLGTPLEHS
SFTYTMGTMGTKINEILPFLTDLTDRFTQMADITDRMAALMRQQQGLTGQQAGASHISLKGAQELKDVTVTMRDTLANFD
DQFRPLRNYFYWEPHCADIPMCWAMRSLFDMTDQVDSMTDAVDDSLKAAVIQDAVTPQLVEVIGKSAAELDNMRKVVLTE
QSTMRPMLTQMNELGRQMMDLGYAFDSSKNDEFFYLPPDAFDNPYFQIDLKYFVSPDGKSARYMIYHDGEALSTEGIDHA
QAYLPKAKEALKGTTLAGSRVYLGGAAATYWDIQDATKTDLLIAAIAAFALIFLVMLVITRSVVAALVIVGTVAFSYSGA
FGLSVLVWQHFLGIPLSWLNLPITFIILVAVGSDYNLLLISRYLEESKAGLNTGLIRAVANSGKVVTTAGIVFATTMMAM
LSSDLLSVGQLGSIIGLGLLLDTLIVRSFITPAIARLLGPLFWWPRLIRSRPAPAQYR

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 102482; Mature: 102351

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHSAQKSLFARMIRKYSILVVLAWVAFTVVINVVVPQLEPVTDANQGPLVPLDAPSSK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCC
ALIHIGESFQESDSNSLAMVILEGDHKLNDADHKFYDVLASKLENDKKHVQYVMNLWGQG
EEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
TTAAGVQSSDGQAAYTLVRVAGDQGSTVSDESIRAVRELVAEVQPPNGVKVYVSGSAPLS
CCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
TDMLQVGNQSMIRLMYVTIVIITVMLLIVYRSFTTAFLTLLIVMVELSCGRGVVAFLAYH
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KLIGISVFASNILVSLILGAGTDYAIFLIGRYQEARHAGEDRETAYYSAVKGVSHVILGS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHCC
GLAIAGATFCLQFTRLNYFNTMGLPCAAATLVAVAASLTFGPAVLALGSRFGIFDPKRKA
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHH
DSGIWRKVGTVTVRWPGRILVVSSVVVMIGSITLPTYKPNYNDRIYIAGDVPANQGYAAA
CCCHHHHHCEEEEECCCEEHHHHHHHHHHCCEECCCCCCCCCCEEEEEECCCCCCCCCCC
DRHFPVSKLNSDMLMVESDHDMRNSTDMIALDKVAREVFHTPGVAMIQSVTRPLGTPLEH
CCCCCHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
SSFTYTMGTMGTKINEILPFLTDLTDRFTQMADITDRMAALMRQQQGLTGQQAGASHISL
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
KGAQELKDVTVTMRDTLANFDDQFRPLRNYFYWEPHCADIPMCWAMRSLFDMTDQVDSMT
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DAVDDSLKAAVIQDAVTPQLVEVIGKSAAELDNMRKVVLTEQSTMRPMLTQMNELGRQMM
HHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHH
DLGYAFDSSKNDEFFYLPPDAFDNPYFQIDLKYFVSPDGKSARYMIYHDGEALSTEGIDH
HHHHHCCCCCCCCEEEECCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCHH
AQAYLPKAKEALKGTTLAGSRVYLGGAAATYWDIQDATKTDLLIAAIAAFALIFLVMLVI
HHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
TRSVVAALVIVGTVAFSYSGAFGLSVLVWQHFLGIPLSWLNLPITFIILVAVGSDYNLLL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
ISRYLEESKAGLNTGLIRAVANSGKVVTTAGIVFATTMMAMLSSDLLSVGQLGSIIGLGL
HHHHHHHHHCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDTLIVRSFITPAIARLLGPLFWWPRLIRSRPAPAQYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAHSAQKSLFARMIRKYSILVVLAWVAFTVVINVVVPQLEPVTDANQGPLVPLDAPSSK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCC
ALIHIGESFQESDSNSLAMVILEGDHKLNDADHKFYDVLASKLENDKKHVQYVMNLWGQG
EEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
TTAAGVQSSDGQAAYTLVRVAGDQGSTVSDESIRAVRELVAEVQPPNGVKVYVSGSAPLS
CCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
TDMLQVGNQSMIRLMYVTIVIITVMLLIVYRSFTTAFLTLLIVMVELSCGRGVVAFLAYH
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KLIGISVFASNILVSLILGAGTDYAIFLIGRYQEARHAGEDRETAYYSAVKGVSHVILGS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHCC
GLAIAGATFCLQFTRLNYFNTMGLPCAAATLVAVAASLTFGPAVLALGSRFGIFDPKRKA
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHH
DSGIWRKVGTVTVRWPGRILVVSSVVVMIGSITLPTYKPNYNDRIYIAGDVPANQGYAAA
CCCHHHHHCEEEEECCCEEHHHHHHHHHHCCEECCCCCCCCCCEEEEEECCCCCCCCCCC
DRHFPVSKLNSDMLMVESDHDMRNSTDMIALDKVAREVFHTPGVAMIQSVTRPLGTPLEH
CCCCCHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
SSFTYTMGTMGTKINEILPFLTDLTDRFTQMADITDRMAALMRQQQGLTGQQAGASHISL
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
KGAQELKDVTVTMRDTLANFDDQFRPLRNYFYWEPHCADIPMCWAMRSLFDMTDQVDSMT
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DAVDDSLKAAVIQDAVTPQLVEVIGKSAAELDNMRKVVLTEQSTMRPMLTQMNELGRQMM
HHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHH
DLGYAFDSSKNDEFFYLPPDAFDNPYFQIDLKYFVSPDGKSARYMIYHDGEALSTEGIDH
HHHHHCCCCCCCCEEEECCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCHH
AQAYLPKAKEALKGTTLAGSRVYLGGAAATYWDIQDATKTDLLIAAIAAFALIFLVMLVI
HHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
TRSVVAALVIVGTVAFSYSGAFGLSVLVWQHFLGIPLSWLNLPITFIILVAVGSDYNLLL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
ISRYLEESKAGLNTGLIRAVANSGKVVTTAGIVFATTMMAMLSSDLLSVGQLGSIIGLGL
HHHHHHHHHCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDTLIVRSFITPAIARLLGPLFWWPRLIRSRPAPAQYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]