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The map label for this gene is soxA [H]

Identifier: 169629568

GI number: 169629568

Start: 2533275

End: 2534690

Strand: Direct

Name: soxA [H]

Synonym: MAB_2482

Alternate gene names: 169629568

Gene position: 2533275-2534690 (Clockwise)

Preceding gene: 169629567

Following gene: 169629573

Centisome position: 49.99

GC content: 63.42

Gene sequence:

>1416_bases
ATGTGTGGCACGCGAAACTTACCGGGACCAGATAGGAGATTCCCTGTGAGCAGGATCTATCTGAATGCCTTCGACATGGC
ATGTGTCGGGCATCAGTCGCCCGGCCTGTGGCGTCATCCGGATGATCAGGGGCATCGCTACAAAAGCCTGGGCTACTGGA
CCGATCTCGCCAAGACCCTGGAGGCGGGCGGTTTCGACCTGCTGTTTCTTGCCGACGTGCTGGGTGCGTATGACGTCTAC
GGCGGTTCGCGAGACGCCGCAGTGGCCGACGCCGCCCAATTTCCGGTCAATGATCCGACCTTGGCGGTCTCGGCGATGGC
CGCGGTCACCGAAACCCTCGGGTTCGGACTCACCCTGTCGCTCACTTACGAGCAGCCGTATGCGTTGGCGCGCCGTCTCA
CCACACTGGACCACCTCACCGAAGGGCGAGTGGCCTGGAATATCGTGACATCTTATTTGGACAGTGCGGCAAGGAATTTG
GGGCTGGATGCGCAGATTCCACATGATCAGCGTTATGACATCGCCGAAGAGTACCTACAGGTCTGCTACAAGCTGTGGGA
AGGCTCATGGGAGTCGGGCGCCGTGGTGCGAGACCGTGGGCGAGGGGTCTTCACCGATCCCGCGAAGGTTCACGACATAG
AACACCATGGCCAGTACTTCACCGTTCCGGGACCATTTCTGTGCGAGCCGTCGGCACAGCGCACCCCGCTGCTCTTCCAG
GCTGGTGCCTCGGCGCGCGGAGTTCGGTTTGCGGCCGCGCATGCGGAGGCTGTGTTCGTGTCGGGCCCCACACCCGATGT
GGTGCGTGCACCGGTACGAGCGCTGCGAGCAGAAGCAGCCCGGTTGGGCCGTGACCCCCGGTCCGTCAAGGTGTTCACGA
TGGTGACGCCGATAGTCGCGGAATCTCACGACGCGGCGGTTGCCAAGCTGCTCGAGTATCGCCGATTCGTCAGCGCCGCT
GGGGCATTGGCGCTGTTCGGCGGCTGGACGGGTGTTGATCTGGCTCGATTGGACCCGGACGAACCGTTGCGGCATGTCGA
GACCGAGGCCAATCGTTCGGCACTGGCCTCATTCACCAACGATCCGAAACGGACCTGGACCACGCGGGAGCTGGCGCAGG
AAATAGGGATAGGCGGGCGCGGGCCGGTTTTGGTCGGTACCGGGTCCAGCATCGCGGACGAACTGGAGCGTTGGTCCGAC
GAGGCCGATATCGACGGGTTCAATGTCGCGTATGTGACGACACCCGGGACCTTCGCCGATTTCGCACGCTTGGTGATACC
GGAGCTACGCCGGCGTGGCCGGGTACCGCACCAGCGCGAAAGATGCACTCTGCGTGAGCAACTCGGTGGGTCTGGCCCAT
ATTTGGCCGACACCCATCCGGGCACCGGCTACCGCCGGGCGCCGCTACCCGGCTGA

Upstream 100 bases:

>100_bases
CTCCGTTGATCGCCGCGGCGCTGCTGGCGGCGAATCATGGCGATCCGCGGCTCATCGTGTGCTACTACCTGGCGCTATCG
GTGCTCACCTTCGGCGCGGC

Downstream 100 bases:

>100_bases
CAGACTGGAATGATCGCCGAATCGCTCACTGAGGGCCACCAATAGTTGGTCCAGGACGGCCAGTTCCGCGCGTTTGGCGC
CAACTAGCCGGTGCAGTCGC

Product: monooxygenase

Products: an aldehyde; SO3; H2O; FMN [C]

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MCGTRNLPGPDRRFPVSRIYLNAFDMACVGHQSPGLWRHPDDQGHRYKSLGYWTDLAKTLEAGGFDLLFLADVLGAYDVY
GGSRDAAVADAAQFPVNDPTLAVSAMAAVTETLGFGLTLSLTYEQPYALARRLTTLDHLTEGRVAWNIVTSYLDSAARNL
GLDAQIPHDQRYDIAEEYLQVCYKLWEGSWESGAVVRDRGRGVFTDPAKVHDIEHHGQYFTVPGPFLCEPSAQRTPLLFQ
AGASARGVRFAAAHAEAVFVSGPTPDVVRAPVRALRAEAARLGRDPRSVKVFTMVTPIVAESHDAAVAKLLEYRRFVSAA
GALALFGGWTGVDLARLDPDEPLRHVETEANRSALASFTNDPKRTWTTRELAQEIGIGGRGPVLVGTGSSIADELERWSD
EADIDGFNVAYVTTPGTFADFARLVIPELRRRGRVPHQRERCTLREQLGGSGPYLADTHPGTGYRRAPLPG

Sequences:

>Translated_471_residues
MCGTRNLPGPDRRFPVSRIYLNAFDMACVGHQSPGLWRHPDDQGHRYKSLGYWTDLAKTLEAGGFDLLFLADVLGAYDVY
GGSRDAAVADAAQFPVNDPTLAVSAMAAVTETLGFGLTLSLTYEQPYALARRLTTLDHLTEGRVAWNIVTSYLDSAARNL
GLDAQIPHDQRYDIAEEYLQVCYKLWEGSWESGAVVRDRGRGVFTDPAKVHDIEHHGQYFTVPGPFLCEPSAQRTPLLFQ
AGASARGVRFAAAHAEAVFVSGPTPDVVRAPVRALRAEAARLGRDPRSVKVFTMVTPIVAESHDAAVAKLLEYRRFVSAA
GALALFGGWTGVDLARLDPDEPLRHVETEANRSALASFTNDPKRTWTTRELAQEIGIGGRGPVLVGTGSSIADELERWSD
EADIDGFNVAYVTTPGTFADFARLVIPELRRRGRVPHQRERCTLREQLGGSGPYLADTHPGTGYRRAPLPG
>Mature_471_residues
MCGTRNLPGPDRRFPVSRIYLNAFDMACVGHQSPGLWRHPDDQGHRYKSLGYWTDLAKTLEAGGFDLLFLADVLGAYDVY
GGSRDAAVADAAQFPVNDPTLAVSAMAAVTETLGFGLTLSLTYEQPYALARRLTTLDHLTEGRVAWNIVTSYLDSAARNL
GLDAQIPHDQRYDIAEEYLQVCYKLWEGSWESGAVVRDRGRGVFTDPAKVHDIEHHGQYFTVPGPFLCEPSAQRTPLLFQ
AGASARGVRFAAAHAEAVFVSGPTPDVVRAPVRALRAEAARLGRDPRSVKVFTMVTPIVAESHDAAVAKLLEYRRFVSAA
GALALFGGWTGVDLARLDPDEPLRHVETEANRSALASFTNDPKRTWTTRELAQEIGIGGRGPVLVGTGSSIADELERWSD
EADIDGFNVAYVTTPGTFADFARLVIPELRRRGRVPHQRERCTLREQLGGSGPYLADTHPGTGYRRAPLPG

Specific function: Part of a pathway to remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. This enzyme metabolizes DBT-sulfone (DBTO2 or DBT 5,5-dioxide) to 2- hydroxybiphenyl (2-HBP) [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ntaA/snaA/soxA(dszA) monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1787166, Length=317, Percent_Identity=24.9211356466877, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR016215 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: 1.14.14.5 [C]

Molecular weight: Translated: 51456; Mature: 51456

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGTRNLPGPDRRFPVSRIYLNAFDMACVGHQSPGLWRHPDDQGHRYKSLGYWTDLAKTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EAGGFDLLFLADVLGAYDVYGGSRDAAVADAAQFPVNDPTLAVSAMAAVTETLGFGLTLS
HCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEE
LTYEQPYALARRLTTLDHLTEGRVAWNIVTSYLDSAARNLGLDAQIPHDQRYDIAEEYLQ
EECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
VCYKLWEGSWESGAVVRDRGRGVFTDPAKVHDIEHHGQYFTVPGPFLCEPSAQRTPLLFQ
HHHHHHCCCCCCCCEEEECCCEEECCCHHHCCHHHCCCEEECCCCCEECCCCCCCCEEEE
AGASARGVRFAAAHAEAVFVSGPTPDVVRAPVRALRAEAARLGRDPRSVKVFTMVTPIVA
CCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHH
ESHDAAVAKLLEYRRFVSAAGALALFGGWTGVDLARLDPDEPLRHVETEANRSALASFTN
CCCHHHHHHHHHHHHHHHHHCHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC
DPKRTWTTRELAQEIGIGGRGPVLVGTGSSIADELERWSDEADIDGFNVAYVTTPGTFAD
CCHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHH
FARLVIPELRRRGRVPHQRERCTLREQLGGSGPYLADTHPGTGYRRAPLPG
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCGTRNLPGPDRRFPVSRIYLNAFDMACVGHQSPGLWRHPDDQGHRYKSLGYWTDLAKTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EAGGFDLLFLADVLGAYDVYGGSRDAAVADAAQFPVNDPTLAVSAMAAVTETLGFGLTLS
HCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEE
LTYEQPYALARRLTTLDHLTEGRVAWNIVTSYLDSAARNLGLDAQIPHDQRYDIAEEYLQ
EECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
VCYKLWEGSWESGAVVRDRGRGVFTDPAKVHDIEHHGQYFTVPGPFLCEPSAQRTPLLFQ
HHHHHHCCCCCCCCEEEECCCEEECCCHHHCCHHHCCCEEECCCCCEECCCCCCCCEEEE
AGASARGVRFAAAHAEAVFVSGPTPDVVRAPVRALRAEAARLGRDPRSVKVFTMVTPIVA
CCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHH
ESHDAAVAKLLEYRRFVSAAGALALFGGWTGVDLARLDPDEPLRHVETEANRSALASFTN
CCCHHHHHHHHHHHHHHHHHCHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC
DPKRTWTTRELAQEIGIGGRGPVLVGTGSSIADELERWSDEADIDGFNVAYVTTPGTFAD
CCHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHH
FARLVIPELRRRGRVPHQRERCTLREQLGGSGPYLADTHPGTGYRRAPLPG
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: an alkanesulfonate; O2; FMNH2 [C]

Specific reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + SO3 + H2O + FMN [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961424; 7574582 [H]