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The map label for this gene is ureG

Identifier: 169629513

GI number: 169629513

Start: 2484153

End: 2484845

Strand: Direct

Name: ureG

Synonym: MAB_2427

Alternate gene names: 169629513

Gene position: 2484153-2484845 (Clockwise)

Preceding gene: 169629512

Following gene: 169629514

Centisome position: 49.02

GC content: 66.81

Gene sequence:

>693_bases
ATGCCACCGCACTTGATAGACGGCCAGCCCCACCAGCACATCGACCGGCCGCGACGCGTTCGTCAGCCGGGGGAGCCGCT
GCGCATCGGTATCGGTGGGCCGGTGGGGTCGGGCAAAACCGCGCTGGTCGCCGCGCTGTGCCGCACCTTGCGCGACGAAA
TCTCCGTCGCGGTCCTAACCAACGACATCTACACGACAGAAGACGCCGACTTCCTGCGCCGCCATGCGGTGCTGCCCGAC
GAGCGCATCACGGCGGTGCAGACCGGCGGCTGTCCGCACACCGCCATCCGCGACGACATCACGGCGAACCTCGACGCGAT
CGAGGATCTGATCGCCACCAACGAGCCGCTAGACCTCATCCTCGTCGAATCGGGTGGCGACAATCTCACCGCTACCTTCT
CCTCCGGGCTGATCGACGTGCAGATCTTCGTCATCGATGTCGCGGGCGGCGATAAGGTGCCGCGCAAGGGTGGTCCCGGC
GTGACCTTCTCGGATCTACTGGTGATCAACAAGACCGATCTGGCACCGATGGTCGGCGCGGATCTCACCGTGATGGCGCG
CGATGCCGCGGCCGTGCGCGAGGGCCGGCCGACGGCGATGATCTCGTTGACCGAGGACCCCGCGGCTTCCGAGGTGTTGG
CCTGGGTGCGTGCGCATCTCACCGAGGCGCACCAAACGGACCATGCGCACTGA

Upstream 100 bases:

>100_bases
GGCCAGTCTGTCCGACCCGCTGCTGGACGTGCTCGCCGAGCAGCACCTGACACGTGAACGCCCGCTTTTTGTTTCGTAGT
CCTCACAAGATTGGATCGTT

Downstream 100 bases:

>100_bases
CGTCCACATCATCGCGGAGAAGGGCCGGCTCCCTCGGCTGCGCTGCACGGGCAGTCTGCAGGGGCGAATCACCGACACCG
ATACCGTCCATCTCGTCGGC

Product: urease accessory protein (UreG)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPPHLIDGQPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDEISVAVLTNDIYTTEDADFLRRHAVLPD
ERITAVQTGGCPHTAIRDDITANLDAIEDLIATNEPLDLILVESGGDNLTATFSSGLIDVQIFVIDVAGGDKVPRKGGPG
VTFSDLLVINKTDLAPMVGADLTVMARDAAAVREGRPTAMISLTEDPAASEVLAWVRAHLTEAHQTDHAH

Sequences:

>Translated_230_residues
MPPHLIDGQPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDEISVAVLTNDIYTTEDADFLRRHAVLPD
ERITAVQTGGCPHTAIRDDITANLDAIEDLIATNEPLDLILVESGGDNLTATFSSGLIDVQIFVIDVAGGDKVPRKGGPG
VTFSDLLVINKTDLAPMVGADLTVMARDAAAVREGRPTAMISLTEDPAASEVLAWVRAHLTEAHQTDHAH
>Mature_229_residues
PPHLIDGQPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDEISVAVLTNDIYTTEDADFLRRHAVLPDE
RITAVQTGGCPHTAIRDDITANLDAIEDLIATNEPLDLILVESGGDNLTATFSSGLIDVQIFVIDVAGGDKVPRKGGPGV
TFSDLLVINKTDLAPMVGADLTVMARDAAAVREGRPTAMISLTEDPAASEVLAWVRAHLTEAHQTDHAH

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_MYCA9 (B1MB87)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703162.1
- ProteinModelPortal:   B1MB87
- EnsemblBacteria:   EBMYCT00000008927
- GeneID:   5964937
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2427
- GeneTree:   EBGT00050000016845
- HOGENOM:   HBG364734
- OMA:   DDIPRKG
- ProtClustDB:   CLSK871974
- BioCyc:   MABS561007:MAB_2427-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 24528; Mature: 24397

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPHLIDGQPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDEISVAVLT
CCCCCCCCCCHHHHCCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCEEEEEE
NDIYTTEDADFLRRHAVLPDERITAVQTGGCPHTAIRDDITANLDAIEDLIATNEPLDLI
CCEECCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCHHCCHHHHHHHHHCCCCEEEE
LVESGGDNLTATFSSGLIDVQIFVIDVAGGDKVPRKGGPGVTFSDLLVINKTDLAPMVGA
EEECCCCEEEEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHEEEEECCCCCHHCCC
DLTVMARDAAAVREGRPTAMISLTEDPAASEVLAWVRAHLTEAHQTDHAH
CEEEEECCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PPHLIDGQPHQHIDRPRRVRQPGEPLRIGIGGPVGSGKTALVAALCRTLRDEISVAVLT
CCCCCCCCCHHHHCCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCEEEEEE
NDIYTTEDADFLRRHAVLPDERITAVQTGGCPHTAIRDDITANLDAIEDLIATNEPLDLI
CCEECCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCHHCCHHHHHHHHHCCCCEEEE
LVESGGDNLTATFSSGLIDVQIFVIDVAGGDKVPRKGGPGVTFSDLLVINKTDLAPMVGA
EEECCCCEEEEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHEEEEECCCCCHHCCC
DLTVMARDAAAVREGRPTAMISLTEDPAASEVLAWVRAHLTEAHQTDHAH
CEEEEECCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA