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The map label for this gene is pgsA1 [H]

Identifier: 169629484

GI number: 169629484

Start: 2455444

End: 2456040

Strand: Direct

Name: pgsA1 [H]

Synonym: MAB_2398

Alternate gene names: 169629484

Gene position: 2455444-2456040 (Clockwise)

Preceding gene: 169629483

Following gene: 169629485

Centisome position: 48.46

GC content: 62.31

Gene sequence:

>597_bases
ATGGGAACCGCGGAACCGTCCACCGGAGACGACCGGATAGTGACGGTCCCCAACCTGCTGAGCGTCATTCGGCTGGCATT
CATCCCACTGTTCCTGTACCTGCTGCTGGTCAGGCATGCCGACGGGTGGGCGGTGGCCATCTTGATGCTCAGCGGGTTCA
CCGACTGGGCCGACGGCAAGATCGCCCGGCTGATGAATCAGTCGTCGCACCTCGGGACACTGCTGGATCCGGCCGCGGAT
CGCCTCTACATGGTGACCACGCCGATAGCCTTCGCCATCCGGGACATCGTGCCATGGTGGATCGTGATCACCCTGCTGGC
ACGCGATCTCATTCTCACCCTGGGGCTACCCGTCGTGCGCCGACGTGGAATCGAGGCACTGCCGGTCATCTACATCGGCA
AGGCCGCCACCTTCGCACTGATGTCGGCATTTCCGCTCATCCTGATCGGTGAATGGGACTCCTTGTGGGGCAGAGTGATC
GGTCCATGCGGGTGGGCGTTCCTCATCTGGGGCTTGGGCATGTACTTGTGGACGTTCGTGCTCTACGTCGCGCAGATCGT
GATGATCGTGCGACGACTGCCGAAGGTGGACACCTGA

Upstream 100 bases:

>100_bases
ACGACAGCCTCTCGATCCTGAACCTGCCCGGCGTCTTCAGCTGACGACAGGCCGCCCATTTGCGCGGGGTATCGCTTCGC
GAATATGAGAGGCTGGCCGG

Downstream 100 bases:

>100_bases
CATGGACGCACAGGACACCTCGGCGAACGGCAAAGAGCCCCAGATACACGGCACCGGCCCGCACCTCATGGGTGGTTTCG
AGCCGGAGGAGGGGCTGGGC

Product: putative phosphatidylglycerophosphate synthase PgsA2

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MGTAEPSTGDDRIVTVPNLLSVIRLAFIPLFLYLLLVRHADGWAVAILMLSGFTDWADGKIARLMNQSSHLGTLLDPAAD
RLYMVTTPIAFAIRDIVPWWIVITLLARDLILTLGLPVVRRRGIEALPVIYIGKAATFALMSAFPLILIGEWDSLWGRVI
GPCGWAFLIWGLGMYLWTFVLYVAQIVMIVRRLPKVDT

Sequences:

>Translated_198_residues
MGTAEPSTGDDRIVTVPNLLSVIRLAFIPLFLYLLLVRHADGWAVAILMLSGFTDWADGKIARLMNQSSHLGTLLDPAAD
RLYMVTTPIAFAIRDIVPWWIVITLLARDLILTLGLPVVRRRGIEALPVIYIGKAATFALMSAFPLILIGEWDSLWGRVI
GPCGWAFLIWGLGMYLWTFVLYVAQIVMIVRRLPKVDT
>Mature_197_residues
GTAEPSTGDDRIVTVPNLLSVIRLAFIPLFLYLLLVRHADGWAVAILMLSGFTDWADGKIARLMNQSSHLGTLLDPAADR
LYMVTTPIAFAIRDIVPWWIVITLLARDLILTLGLPVVRRRGIEALPVIYIGKAATFALMSAFPLILIGEWDSLWGRVIG
PCGWAFLIWGLGMYLWTFVLYVAQIVMIVRRLPKVDT

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=140, Percent_Identity=31.4285714285714, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320059, Length=130, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22090; Mature: 21959

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTAEPSTGDDRIVTVPNLLSVIRLAFIPLFLYLLLVRHADGWAVAILMLSGFTDWADGK
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHH
IARLMNQSSHLGTLLDPAADRLYMVTTPIAFAIRDIVPWWIVITLLARDLILTLGLPVVR
HHHHHCCCCCCCHHHCHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRGIEALPVIYIGKAATFALMSAFPLILIGEWDSLWGRVIGPCGWAFLIWGLGMYLWTFV
HCCCCCCCCEEECHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYVAQIVMIVRRLPKVDT
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GTAEPSTGDDRIVTVPNLLSVIRLAFIPLFLYLLLVRHADGWAVAILMLSGFTDWADGK
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHH
IARLMNQSSHLGTLLDPAADRLYMVTTPIAFAIRDIVPWWIVITLLARDLILTLGLPVVR
HHHHHCCCCCCCHHHCHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRGIEALPVIYIGKAATFALMSAFPLILIGEWDSLWGRVIGPCGWAFLIWGLGMYLWTFV
HCCCCCCCCEEECHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYVAQIVMIVRRLPKVDT
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]