| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is secA2 [H]
Identifier: 169629483
GI number: 169629483
Start: 2453069
End: 2455387
Strand: Direct
Name: secA2 [H]
Synonym: MAB_2397
Alternate gene names: 169629483
Gene position: 2453069-2455387 (Clockwise)
Preceding gene: 169629482
Following gene: 169629484
Centisome position: 48.41
GC content: 65.42
Gene sequence:
>2319_bases GTGCGCAAGTCGAACACCGCCTCACGGTTCACCGGGAAGTTCTGGAAGCTGCTCGGTGCCGCTACCGACAAGAACCAAAG CCAGTCGCTGGCCCTCGTGGACGCCTCGAAGAAGTATGACGAGAAGGCCAAGGACCTCACCGACGAGCAGCTCACCAAGG CGGCGAAGAAACTCGATCTCACCGAGGGCCTCGAGTCCAAGGACATCGGCCAGTTCCTCGCGATCGTGCGTGAGGCCGCC GAACGCACCATCGACGAGCGCCCATTCGACGTTCAGCTGCTGGGTGCGCTGCGCATGCTGGACGGCGACGTCATCGAGAT GGCCACGGGTGAGGGCAAGACCTTGACCGGTGCGATCACCGCCGCCGGATACGCGCTGGGCGGGCGCAGTGTGCACGTCA TCTCCGTCAACGACTACCTGGCCCGGCGCGACGCCGAATGGATGGGGCCGTTCCTGGAGCGCATGGGCCTGACGGTCGGG TGGATCACCGAGGAATCGACCGCCGAGGAGCGCCGCAAGGCCTACGCCTGCGACGTCACCTACGGGTCGGTCAACGAAAT CGGTTTCGACGTGCTGCGTGACCAGCTGGCCATTGACGTCGACGACCTGGTGTCGCCGAGCCCCGACGTGGCCGTGGTCG ACGAGGCCGACTCGGTGCTCGTGGACGAGGCACTGGTTCCCCTGGTGCTGGCGGGTACCAGCCATCGGGAAGCGCCGAGC TCTGAGGTCATCGAAGCGGTACGCGAGCTGATCGCCGGAGAGGACTACGAGGCCGACAACGATCGCCGCAATATCTTCCT CACCGACACCGGTGCCCGGAAGCTGGAGAAGCAGCTGGGAAATATCGACCTGTATTCCGAACATCATGTCGGAACCACCC TGACCGAGGTCAACGTCGCGCTGCACGCCCATGTGCTCCTGGAGCGCGATGTCCACTACATCGTGCGCGACGGCGCCGTG CATCTCATCAACTCCTCACGCGGGCGCATCGCGGCCCTGCAGCGCTGGCCCGACGGCCTGCAAGCGGCCGTCGAAGCCAA AGAAGGAATCGAAACCACCGATACCGGTGAGGTTCTCGACACCATCACCGTGCAGGCGCTCATCAACCGCTACCCGCGGG TCAGCGGCATGACCGGTACAGCGCTCGCGGCCGGCGAACAGCTGCGGCAGTTCTACAAACTGGGTGTCTCACCGATCCCG CCCAACACGCCGAACATTCGTGAAGACCAGCCCGACCGCGTGTACATCACCGAGGCAAGCAAGAACGACGCCATCGTCGC GCATATCGCCGAGATCCACGCCACCGGTCAGCCGGTGCTCGTCGGCACCCATGACGTCGCCGAATCCGAGGCGCTGCATC ACCGTCTGGTGCGGGCCGGAGTTCCCGCGGTGGTGCTGAACGCCAAGAACGATGCCGAAGAAGCCCGCGTCATCGCCGAG GCCGGAGCCCTCAAGGCCGTCACGGTGTCGACGCAGATGGCCGGCCGGGGTACCGATATCCGCCTCGGCGGCTCCGATGA GACCGACTACGACGCCGTCGTCGAGGCTGGCGGGCTGCACGTCGTCGGCACCGGGCGGCACCGCACCGAACGACTCGACA ACCAGTTGCGTGGACGCGCGGGGCGCCAGGGCGACCCGGGATCGTCGGTCTTCTTCTCCAGCTGGGAGGACGAGGTGGTT GTGGCACATCTGGATTCGGCCAAGCTGCCCACCGAAACCGATGAGAACGGTCGGATAGTCAGCCCCAAGGCGGGCGGCCT CATCGACCACGCCCAGCGCGTGGCCGAGGGCGCGATGCTTGACCTGCACGCCAACACCTGGCGATACAACCAACTGATCG CTCAGCAGCGTGCGATCATTTCCGATCGCCGGGATACCTTGTTGCGCACCGACACCGCCCGCAAGGAGCTTCAGGAGCGC TCCCCGGAGCGCTATGACGAGCTGGCCGAGGAACTTTCCGAAGAGTGGCTGGAGCGCATCTCGCGGCAGATCATGCTGTA TCACCTGGATCGGGGCTGGGCCGACCATCTGGCCTACCTCTCGGACGTGCGCGAGAGCATTCACCTGCGCGCACTGGGAC GCCAGAACCCGATCGACGAATTCCACCGGCTGGCTGTCGATGCCTTCGCGTCGCTGGCCGCCGACGCCGTGGAGGCCGCC CAGCAGACCTTCGAGACCGCGAATCTGGTTGACGAGGAACAGGGATTGGATCTGTCGAAGCTCGCCCGGCCGACCTCGAC GTGGACGTACATGATCCACGACGACCCGCGCAAGAACGACAGCCTCTCGATCCTGAACCTGCCCGGCGTCTTCAGCTGA
Upstream 100 bases:
>100_bases TCGCAAGCTCGGATTCCGGGCAGTCTCCGATTCGGTGATCGTCGAGTTCACCTGACAGTGCTCATCGGGGGCCTCCTGGC CCCTGACGTACCGTGTGCAT
Downstream 100 bases:
>100_bases CGACAGGCCGCCCATTTGCGCGGGGTATCGCTTCGCGAATATGAGAGGCTGGCCGGATGGGAACCGCGGAACCGTCCACC GGAGACGACCGGATAGTGAC
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 772; Mature: 772
Protein sequence:
>772_residues MRKSNTASRFTGKFWKLLGAATDKNQSQSLALVDASKKYDEKAKDLTDEQLTKAAKKLDLTEGLESKDIGQFLAIVREAA ERTIDERPFDVQLLGALRMLDGDVIEMATGEGKTLTGAITAAGYALGGRSVHVISVNDYLARRDAEWMGPFLERMGLTVG WITEESTAEERRKAYACDVTYGSVNEIGFDVLRDQLAIDVDDLVSPSPDVAVVDEADSVLVDEALVPLVLAGTSHREAPS SEVIEAVRELIAGEDYEADNDRRNIFLTDTGARKLEKQLGNIDLYSEHHVGTTLTEVNVALHAHVLLERDVHYIVRDGAV HLINSSRGRIAALQRWPDGLQAAVEAKEGIETTDTGEVLDTITVQALINRYPRVSGMTGTALAAGEQLRQFYKLGVSPIP PNTPNIREDQPDRVYITEASKNDAIVAHIAEIHATGQPVLVGTHDVAESEALHHRLVRAGVPAVVLNAKNDAEEARVIAE AGALKAVTVSTQMAGRGTDIRLGGSDETDYDAVVEAGGLHVVGTGRHRTERLDNQLRGRAGRQGDPGSSVFFSSWEDEVV VAHLDSAKLPTETDENGRIVSPKAGGLIDHAQRVAEGAMLDLHANTWRYNQLIAQQRAIISDRRDTLLRTDTARKELQER SPERYDELAEELSEEWLERISRQIMLYHLDRGWADHLAYLSDVRESIHLRALGRQNPIDEFHRLAVDAFASLAADAVEAA QQTFETANLVDEEQGLDLSKLARPTSTWTYMIHDDPRKNDSLSILNLPGVFS
Sequences:
>Translated_772_residues MRKSNTASRFTGKFWKLLGAATDKNQSQSLALVDASKKYDEKAKDLTDEQLTKAAKKLDLTEGLESKDIGQFLAIVREAA ERTIDERPFDVQLLGALRMLDGDVIEMATGEGKTLTGAITAAGYALGGRSVHVISVNDYLARRDAEWMGPFLERMGLTVG WITEESTAEERRKAYACDVTYGSVNEIGFDVLRDQLAIDVDDLVSPSPDVAVVDEADSVLVDEALVPLVLAGTSHREAPS SEVIEAVRELIAGEDYEADNDRRNIFLTDTGARKLEKQLGNIDLYSEHHVGTTLTEVNVALHAHVLLERDVHYIVRDGAV HLINSSRGRIAALQRWPDGLQAAVEAKEGIETTDTGEVLDTITVQALINRYPRVSGMTGTALAAGEQLRQFYKLGVSPIP PNTPNIREDQPDRVYITEASKNDAIVAHIAEIHATGQPVLVGTHDVAESEALHHRLVRAGVPAVVLNAKNDAEEARVIAE AGALKAVTVSTQMAGRGTDIRLGGSDETDYDAVVEAGGLHVVGTGRHRTERLDNQLRGRAGRQGDPGSSVFFSSWEDEVV VAHLDSAKLPTETDENGRIVSPKAGGLIDHAQRVAEGAMLDLHANTWRYNQLIAQQRAIISDRRDTLLRTDTARKELQER SPERYDELAEELSEEWLERISRQIMLYHLDRGWADHLAYLSDVRESIHLRALGRQNPIDEFHRLAVDAFASLAADAVEAA QQTFETANLVDEEQGLDLSKLARPTSTWTYMIHDDPRKNDSLSILNLPGVFS >Mature_772_residues MRKSNTASRFTGKFWKLLGAATDKNQSQSLALVDASKKYDEKAKDLTDEQLTKAAKKLDLTEGLESKDIGQFLAIVREAA ERTIDERPFDVQLLGALRMLDGDVIEMATGEGKTLTGAITAAGYALGGRSVHVISVNDYLARRDAEWMGPFLERMGLTVG WITEESTAEERRKAYACDVTYGSVNEIGFDVLRDQLAIDVDDLVSPSPDVAVVDEADSVLVDEALVPLVLAGTSHREAPS SEVIEAVRELIAGEDYEADNDRRNIFLTDTGARKLEKQLGNIDLYSEHHVGTTLTEVNVALHAHVLLERDVHYIVRDGAV HLINSSRGRIAALQRWPDGLQAAVEAKEGIETTDTGEVLDTITVQALINRYPRVSGMTGTALAAGEQLRQFYKLGVSPIP PNTPNIREDQPDRVYITEASKNDAIVAHIAEIHATGQPVLVGTHDVAESEALHHRLVRAGVPAVVLNAKNDAEEARVIAE AGALKAVTVSTQMAGRGTDIRLGGSDETDYDAVVEAGGLHVVGTGRHRTERLDNQLRGRAGRQGDPGSSVFFSSWEDEVV VAHLDSAKLPTETDENGRIVSPKAGGLIDHAQRVAEGAMLDLHANTWRYNQLIAQQRAIISDRRDTLLRTDTARKELQER SPERYDELAEELSEEWLERISRQIMLYHLDRGWADHLAYLSDVRESIHLRALGRQNPIDEFHRLAVDAFASLAADAVEAA QQTFETANLVDEEQGLDLSKLARPTSTWTYMIHDDPRKNDSLSILNLPGVFS
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=814, Percent_Identity=37.2235872235872, Blast_Score=433, Evalue=1e-122,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 84815; Mature: 84815
Theoretical pI: Translated: 4.71; Mature: 4.71
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.4 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRKSNTASRFTGKFWKLLGAATDKNQSQSLALVDASKKYDEKAKDLTDEQLTKAAKKLDL CCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHH TEGLESKDIGQFLAIVREAAERTIDERPFDVQLLGALRMLDGDVIEMATGEGKTLTGAIT HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEHH AAGYALGGRSVHVISVNDYLARRDAEWMGPFLERMGLTVGWITEESTAEERRKAYACDVT HHCEEECCCEEEEEECCHHHHHCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHEEEEEEE YGSVNEIGFDVLRDQLAIDVDDLVSPSPDVAVVDEADSVLVDEALVPLVLAGTSHREAPS CCCHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHEEECCCCCCCCH SEVIEAVRELIAGEDYEADNDRRNIFLTDTGARKLEKQLGNIDLYSEHHVGTTLTEVNVA HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHCCEEEEECCCCCCCHHHHHHH LHAHVLLERDVHYIVRDGAVHLINSSRGRIAALQRWPDGLQAAVEAKEGIETTDTGEVLD HHHHHHHHCCHHEEEECCEEEEEECCCCCEEEHHHCCHHHHHHHHHHHCCCCCCCHHHHH TITVQALINRYPRVSGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIREDQPDRVYITEAS HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECC KNDAIVAHIAEIHATGQPVLVGTHDVAESEALHHRLVRAGVPAVVLNAKNDAEEARVIAE CCCEEEEEHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH AGALKAVTVSTQMAGRGTDIRLGGSDETDYDAVVEAGGLHVVGTGRHRTERLDNQLRGRA CCCEEEEEEEHHHCCCCCEEEECCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHCCC GRQGDPGSSVFFSSWEDEVVVAHLDSAKLPTETDENGRIVSPKAGGLIDHAQRVAEGAML CCCCCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEE DLHANTWRYNQLIAQQRAIISDRRDTLLRTDTARKELQERSPERYDELAEELSEEWLERI EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH SRQIMLYHLDRGWADHLAYLSDVRESIHLRALGRQNPIDEFHRLAVDAFASLAADAVEAA HHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH QQTFETANLVDEEQGLDLSKLARPTSTWTYMIHDDPRKNDSLSILNLPGVFS HHHHHHHHHCCHHCCCCHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCC >Mature Secondary Structure MRKSNTASRFTGKFWKLLGAATDKNQSQSLALVDASKKYDEKAKDLTDEQLTKAAKKLDL CCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHH TEGLESKDIGQFLAIVREAAERTIDERPFDVQLLGALRMLDGDVIEMATGEGKTLTGAIT HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEHH AAGYALGGRSVHVISVNDYLARRDAEWMGPFLERMGLTVGWITEESTAEERRKAYACDVT HHCEEECCCEEEEEECCHHHHHCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHEEEEEEE YGSVNEIGFDVLRDQLAIDVDDLVSPSPDVAVVDEADSVLVDEALVPLVLAGTSHREAPS CCCHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHEEECCCCCCCCH SEVIEAVRELIAGEDYEADNDRRNIFLTDTGARKLEKQLGNIDLYSEHHVGTTLTEVNVA HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHCCEEEEECCCCCCCHHHHHHH LHAHVLLERDVHYIVRDGAVHLINSSRGRIAALQRWPDGLQAAVEAKEGIETTDTGEVLD HHHHHHHHCCHHEEEECCEEEEEECCCCCEEEHHHCCHHHHHHHHHHHCCCCCCCHHHHH TITVQALINRYPRVSGMTGTALAAGEQLRQFYKLGVSPIPPNTPNIREDQPDRVYITEAS HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECC KNDAIVAHIAEIHATGQPVLVGTHDVAESEALHHRLVRAGVPAVVLNAKNDAEEARVIAE CCCEEEEEHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH AGALKAVTVSTQMAGRGTDIRLGGSDETDYDAVVEAGGLHVVGTGRHRTERLDNQLRGRA CCCEEEEEEEHHHCCCCCEEEECCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHCCC GRQGDPGSSVFFSSWEDEVVVAHLDSAKLPTETDENGRIVSPKAGGLIDHAQRVAEGAML CCCCCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEE DLHANTWRYNQLIAQQRAIISDRRDTLLRTDTARKELQERSPERYDELAEELSEEWLERI EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH SRQIMLYHLDRGWADHLAYLSDVRESIHLRALGRQNPIDEFHRLAVDAFASLAADAVEAA HHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH QQTFETANLVDEEQGLDLSKLARPTSTWTYMIHDDPRKNDSLSILNLPGVFS HHHHHHHHHCCHHCCCCHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA