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The map label for this gene is argE [H]

Identifier: 169629397

GI number: 169629397

Start: 2363161

End: 2364612

Strand: Direct

Name: argE [H]

Synonym: MAB_2311

Alternate gene names: 169629397

Gene position: 2363161-2364612 (Clockwise)

Preceding gene: 169629396

Following gene: 169629398

Centisome position: 46.64

GC content: 63.15

Gene sequence:

>1452_bases
ATGAACGACACCATGCACCGGATTCTCACTCTCGCCGTCGCCGTGCTCGCCCTCGCGTCCTGCGGAACAACGCAGAACCA
GGGTTCTCCGGCGACCACCGTCCCCGCCGTCAACGACGATCGCGGCGCGTTTCGAGATCTGTACCGGGAATTGGTCGAAA
CCAACACAACGGCGTCGCAGGGGAGTTGCACCGAGGCCGCGCAGAAGATGGCCGCGCGCCTCAAGGGCGCCGGATACGCG
GACAAGGACCTGGTGTTTTTCAGCCCGCCGGATCACCCCAAGGACGGCGGGCTGGTGGCGACTCTGGGTGGCTCCGATGC
TGCCGCCAAACCGATTCTGCTCCTGGCACATATCGACGTCGTCGAGGCCAAACGCGAGGACTGGAAGCGTGATCCGTTCA
CGCTCGCCGAGGACAATGGGTATTTCTATGCGCGCGGAGCCGAGGATGACAAGGCGATGGCCGCAATCTTTGTGGACAGC
CTGATGCGGTACCGCACGGAGAATTTTGTCCCGAAACGCCCGATTCGCGTCGCACTGACCTGCGGTGAAGAGGGCGGCGG
CCAGGTCAACGGTGCCGAGTGGCTCCATCAGAATCGGCCCCAGCTCGTTGACGCCGAATTCGTCATCAACGAGGGTGCCG
GTGGCGATCTGAATGAGGACAACAAACCCGTTCTGCTGGAAATCCAGGCAGGTCAGAAGATCTATCAGGACTTCACCCTC
GAGGTGACCGACGAGGGCGGACACAGCAGCCAGCCCGGATCGTTCAATGCGATACAGGCCCTCGGGGCGGCCCTGAACCG
TCTTGCCGCCACGCCGTTCCCCGTCCAGCTCAACGACATCACCCGGGCCTACTTCAAGGCTCAGGCCCCGCTGCGGCCGG
GTGAGGTGGGCCAGGCCATGTCGACAATCGTTGCCAATCCGCAAGATCCGGCCGCCGTAGCGGTACTTTCGAGAAATCCC
CTCTACAACGCGATGTTGCGTACCACCTGTGTGCCGACGAAAATTGAAGGCGGACATGCCAACAACGCGTTGCCGCAACG
TGCTACCGCCAATGTGAACTGCCGAATACTGCCCGGGCCAGGCTCGGTGCAGCAGGGAGCCCAGGACGCCATCGTCAAGG
CCGTCAACGACCCCAAGATCACGGTGAAGCCCGCCGCACCCTTCCGCGCCAATGTTGCGAGCGTCCCGCCGTTGACTCCG
CAGATCGTGGACCCCATCAAGGCCGTGGCCGGTGCGATGTGGCCGGGTGTGCCCCTGGTGCCCACCATGTCCACCGGCGC
GACAGACGCGATCTACTTCGGCCGTACTCCTGTGTACGGACTCAGCGGCATATTCGCCCAGCCGGGGGAGACGCACGCGC
ACGGTCTGGATGAACGAATCCAGGTGAAATCCCTCTATGACGGCCGCGCGTTTCTGTATCAAGTAGTCAAGCTCTACGCG
AACGGCGCGTGA

Upstream 100 bases:

>100_bases
GTGGTGTCTGTCAGGGTGTTTCGCACGGGCTCCGCATCGGAGATGACGGATCGGGCCGGGCAACAGGCGGTTCGCATCCC
CAGCTAGGCGTCACAGGTGT

Downstream 100 bases:

>100_bases
TCGTCCTCATAACCAGATTGAGGCGCGCGCCATACCTGTCCGGCGATCCGACGAGGGAAAATCACCCCTATAGCCCGACA
CAATCGGCCAAATGACGCAT

Product: hypothetical protein

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYRELVETNTTASQGSCTEAAQKMAARLKGAGYA
DKDLVFFSPPDHPKDGGLVATLGGSDAAAKPILLLAHIDVVEAKREDWKRDPFTLAEDNGYFYARGAEDDKAMAAIFVDS
LMRYRTENFVPKRPIRVALTCGEEGGGQVNGAEWLHQNRPQLVDAEFVINEGAGGDLNEDNKPVLLEIQAGQKIYQDFTL
EVTDEGGHSSQPGSFNAIQALGAALNRLAATPFPVQLNDITRAYFKAQAPLRPGEVGQAMSTIVANPQDPAAVAVLSRNP
LYNAMLRTTCVPTKIEGGHANNALPQRATANVNCRILPGPGSVQQGAQDAIVKAVNDPKITVKPAAPFRANVASVPPLTP
QIVDPIKAVAGAMWPGVPLVPTMSTGATDAIYFGRTPVYGLSGIFAQPGETHAHGLDERIQVKSLYDGRAFLYQVVKLYA
NGA

Sequences:

>Translated_483_residues
MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYRELVETNTTASQGSCTEAAQKMAARLKGAGYA
DKDLVFFSPPDHPKDGGLVATLGGSDAAAKPILLLAHIDVVEAKREDWKRDPFTLAEDNGYFYARGAEDDKAMAAIFVDS
LMRYRTENFVPKRPIRVALTCGEEGGGQVNGAEWLHQNRPQLVDAEFVINEGAGGDLNEDNKPVLLEIQAGQKIYQDFTL
EVTDEGGHSSQPGSFNAIQALGAALNRLAATPFPVQLNDITRAYFKAQAPLRPGEVGQAMSTIVANPQDPAAVAVLSRNP
LYNAMLRTTCVPTKIEGGHANNALPQRATANVNCRILPGPGSVQQGAQDAIVKAVNDPKITVKPAAPFRANVASVPPLTP
QIVDPIKAVAGAMWPGVPLVPTMSTGATDAIYFGRTPVYGLSGIFAQPGETHAHGLDERIQVKSLYDGRAFLYQVVKLYA
NGA
>Mature_483_residues
MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYRELVETNTTASQGSCTEAAQKMAARLKGAGYA
DKDLVFFSPPDHPKDGGLVATLGGSDAAAKPILLLAHIDVVEAKREDWKRDPFTLAEDNGYFYARGAEDDKAMAAIFVDS
LMRYRTENFVPKRPIRVALTCGEEGGGQVNGAEWLHQNRPQLVDAEFVINEGAGGDLNEDNKPVLLEIQAGQKIYQDFTL
EVTDEGGHSSQPGSFNAIQALGAALNRLAATPFPVQLNDITRAYFKAQAPLRPGEVGQAMSTIVANPQDPAAVAVLSRNP
LYNAMLRTTCVPTKIEGGHANNALPQRATANVNCRILPGPGSVQQGAQDAIVKAVNDPKITVKPAAPFRANVASVPPLTP
QIVDPIKAVAGAMWPGVPLVPTMSTGATDAIYFGRTPVYGLSGIFAQPGETHAHGLDERIQVKSLYDGRAFLYQVVKLYA
NGA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Homo sapiens, GI269846968, Length=401, Percent_Identity=29.6758104738155, Blast_Score=139, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6322289, Length=276, Percent_Identity=28.2608695652174, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24649210, Length=389, Percent_Identity=22.6221079691517, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 51408; Mature: 51408

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYRELVETNTTASQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GSCTEAAQKMAARLKGAGYADKDLVFFSPPDHPKDGGLVATLGGSDAAAKPILLLAHIDV
CCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEEEEECHH
VEAKREDWKRDPFTLAEDNGYFYARGAEDDKAMAAIFVDSLMRYRTENFVPKRPIRVALT
HHHHHHHCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
CGEEGGGQVNGAEWLHQNRPQLVDAEFVINEGAGGDLNEDNKPVLLEIQAGQKIYQDFTL
ECCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEECCCCHHHCCEEE
EVTDEGGHSSQPGSFNAIQALGAALNRLAATPFPVQLNDITRAYFKAQAPLRPGEVGQAM
EEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHH
STIVANPQDPAAVAVLSRNPLYNAMLRTTCVPTKIEGGHANNALPQRATANVNCRILPGP
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GSVQQGAQDAIVKAVNDPKITVKPAAPFRANVASVPPLTPQIVDPIKAVAGAMWPGVPLV
CCHHCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
PTMSTGATDAIYFGRTPVYGLSGIFAQPGETHAHGLDERIQVKSLYDGRAFLYQVVKLYA
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHCCCCCCEEEEHCCCCHHHHHHHHHHHH
NGA
CCC
>Mature Secondary Structure
MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYRELVETNTTASQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GSCTEAAQKMAARLKGAGYADKDLVFFSPPDHPKDGGLVATLGGSDAAAKPILLLAHIDV
CCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEEEEECHH
VEAKREDWKRDPFTLAEDNGYFYARGAEDDKAMAAIFVDSLMRYRTENFVPKRPIRVALT
HHHHHHHCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
CGEEGGGQVNGAEWLHQNRPQLVDAEFVINEGAGGDLNEDNKPVLLEIQAGQKIYQDFTL
ECCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEECCCCHHHCCEEE
EVTDEGGHSSQPGSFNAIQALGAALNRLAATPFPVQLNDITRAYFKAQAPLRPGEVGQAM
EEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHH
STIVANPQDPAAVAVLSRNPLYNAMLRTTCVPTKIEGGHANNALPQRATANVNCRILPGP
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GSVQQGAQDAIVKAVNDPKITVKPAAPFRANVASVPPLTPQIVDPIKAVAGAMWPGVPLV
CCHHCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
PTMSTGATDAIYFGRTPVYGLSGIFAQPGETHAHGLDERIQVKSLYDGRAFLYQVVKLYA
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHCCCCCCEEEEHCCCCHHHHHHHHHHHH
NGA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA