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The map label for this gene is yebQ [C]

Identifier: 169629396

GI number: 169629396

Start: 2361711

End: 2363147

Strand: Direct

Name: yebQ [C]

Synonym: MAB_2310

Alternate gene names: 169629396

Gene position: 2361711-2363147 (Clockwise)

Preceding gene: 169629394

Following gene: 169629397

Centisome position: 46.61

GC content: 66.81

Gene sequence:

>1437_bases
ATGGTTCGCGAGTTGGGCGCCGGTGGTTGGCGAGATCTGTTGGACGGGCGCCAACTCGGAATCGTCACCGTCCTGGCTGG
CGGCGTGGCGCTATACGCCACGAATGTCTACCTCACCACCAGTCTGTTACCAAGCGCAGTTGTGGAGATCGGCGGCGAGC
GCTTCTATGCCTGGGTGACAACGGTGTACCTGATCGCCTCGGTGAGTGCCGCCACAGTGGTGAGCCCCCTGCTGGGGTGG
GCCGGCCCACGCGGCGCGTACCTTCTGGCCTTCGGGGCCTTCGCGGTTGGCACCCTGGTCTGCGCGGTCGCTCCCGGGAT
GCACGTCTTGCTTGCCGGACGAGCCGTACAGGGTGCGGCGGGTGGACTGCTGGCCGGGCTTGCTTATGCCGTCATCAATT
TGGCGCTGCCACAGGGCCTATGGACTCGGGCATCGGCACTCACCTCGGCGATGTGGGGTGTTGGAACCTTTGTCGGTCCC
GCGGCCGGCGGTCTTTTCGCCCAATGGGGGCTCTGGCGGTGGGCATTCGGGATGCTGGCGGTCATCACCGCGGGGATTGC
CGCGATGGTGCCCTACGTGTTGACGCGCGCGCAAAAGCCGAACGCCGCGCGTGCCGGGAACCAGGTTCCGGTCTGGTCGT
TGCTCGTGCTCACGGCGGCGGCCAGCCTGGTAGCGGCAGCGGGGCTCCAATCGACGTTGCCCTTCATGGCCACGTTGCTC
GCCGCCGCCGTCGTTCTCGTGATCCTCTTCGTCGCGCTCGATCGTCGCTCCCGGGCATCGGTACTGCCGAAGGCGGTATT
CGCGCGCAATCCGCTGAAGTGGATCTACTTGACGATCGCGGTGCTGGCGGTGGCCTCGATGGCCGAGACGTACATTCCCT
TCTTCGGGCAGCGGCTCGGACATCTGAGCCCTGTCGCTGCCGGATTCTTGGGCGCCACCTTGGCATTCGGATGGACTGTC
GGCGAAATGATCAGCGCGTCGGCCCAAGTGCGGACGGTCTCCCGGGTGGTGTCCGTCGCCCCGGCCGTGGTGGCGGCTGG
GCTGTTTCTGGCCGGAGTATTACAGCGCGACGGCGCCACCGTCCTCGAGATCGGGTGCTGGGCACTCGGCTTCGTCGTCA
CGGGTGCGGGTATCGGGATGGCCTGGCCGCATCTGGCGGCCGCAGCGATGTCGGTGTCTGACGACGGTTCGGAAAGCGGG
ACCGGTGCCGCGGCCATCAGCACCGTACAGCTGATCGCCGGAGCTCTTGGCGCCGGACTGGCCGGTGTGTTCGTCAACCT
CGGCGGATCGGCCAGACACGGCGCACAGCTGTTGTTCGTGGGGTTCGCCGTGATGGTGCTGTGCGGTGTAGTGGTGTCTG
TCAGGGTGTTTCGCACGGGCTCCGCATCGGAGATGACGGATCGGGCCGGGCAACAGGCGGTTCGCATCCCCAGCTAG

Upstream 100 bases:

>100_bases
GGCAGCAGCTCGGTCTTGCCCTTCATGAGGCCTCCTCTATGAAGAGATGTTCGCCGCCCAGAGTTGATCTCAAGTGAACT
TTAGCTCATACGGTATCGGC

Downstream 100 bases:

>100_bases
GCGTCACAGGTGTATGAACGACACCATGCACCGGATTCTCACTCTCGCCGTCGCCGTGCTCGCCCTCGCGTCCTGCGGAA
CAACGCAGAACCAGGGTTCT

Product: drug efflux membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MVRELGAGGWRDLLDGRQLGIVTVLAGGVALYATNVYLTTSLLPSAVVEIGGERFYAWVTTVYLIASVSAATVVSPLLGW
AGPRGAYLLAFGAFAVGTLVCAVAPGMHVLLAGRAVQGAAGGLLAGLAYAVINLALPQGLWTRASALTSAMWGVGTFVGP
AAGGLFAQWGLWRWAFGMLAVITAGIAAMVPYVLTRAQKPNAARAGNQVPVWSLLVLTAAASLVAAAGLQSTLPFMATLL
AAAVVLVILFVALDRRSRASVLPKAVFARNPLKWIYLTIAVLAVASMAETYIPFFGQRLGHLSPVAAGFLGATLAFGWTV
GEMISASAQVRTVSRVVSVAPAVVAAGLFLAGVLQRDGATVLEIGCWALGFVVTGAGIGMAWPHLAAAAMSVSDDGSESG
TGAAAISTVQLIAGALGAGLAGVFVNLGGSARHGAQLLFVGFAVMVLCGVVVSVRVFRTGSASEMTDRAGQQAVRIPS

Sequences:

>Translated_478_residues
MVRELGAGGWRDLLDGRQLGIVTVLAGGVALYATNVYLTTSLLPSAVVEIGGERFYAWVTTVYLIASVSAATVVSPLLGW
AGPRGAYLLAFGAFAVGTLVCAVAPGMHVLLAGRAVQGAAGGLLAGLAYAVINLALPQGLWTRASALTSAMWGVGTFVGP
AAGGLFAQWGLWRWAFGMLAVITAGIAAMVPYVLTRAQKPNAARAGNQVPVWSLLVLTAAASLVAAAGLQSTLPFMATLL
AAAVVLVILFVALDRRSRASVLPKAVFARNPLKWIYLTIAVLAVASMAETYIPFFGQRLGHLSPVAAGFLGATLAFGWTV
GEMISASAQVRTVSRVVSVAPAVVAAGLFLAGVLQRDGATVLEIGCWALGFVVTGAGIGMAWPHLAAAAMSVSDDGSESG
TGAAAISTVQLIAGALGAGLAGVFVNLGGSARHGAQLLFVGFAVMVLCGVVVSVRVFRTGSASEMTDRAGQQAVRIPS
>Mature_478_residues
MVRELGAGGWRDLLDGRQLGIVTVLAGGVALYATNVYLTTSLLPSAVVEIGGERFYAWVTTVYLIASVSAATVVSPLLGW
AGPRGAYLLAFGAFAVGTLVCAVAPGMHVLLAGRAVQGAAGGLLAGLAYAVINLALPQGLWTRASALTSAMWGVGTFVGP
AAGGLFAQWGLWRWAFGMLAVITAGIAAMVPYVLTRAQKPNAARAGNQVPVWSLLVLTAAASLVAAAGLQSTLPFMATLL
AAAVVLVILFVALDRRSRASVLPKAVFARNPLKWIYLTIAVLAVASMAETYIPFFGQRLGHLSPVAAGFLGATLAFGWTV
GEMISASAQVRTVSRVVSVAPAVVAAGLFLAGVLQRDGATVLEIGCWALGFVVTGAGIGMAWPHLAAAAMSVSDDGSESG
TGAAAISTVQLIAGALGAGLAGVFVNLGGSARHGAQLLFVGFAVMVLCGVVVSVRVFRTGSASEMTDRAGQQAVRIPS

Specific function: Could be involved in fluoroquinolones efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=389, Percent_Identity=25.1928020565553, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48589; Mature: 48589

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]