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The map label for this gene is dhmA2 [H]

Identifier: 169629375

GI number: 169629375

Start: 2337311

End: 2338261

Strand: Direct

Name: dhmA2 [H]

Synonym: MAB_2289

Alternate gene names: 169629375

Gene position: 2337311-2338261 (Clockwise)

Preceding gene: 169629374

Following gene: 169629376

Centisome position: 46.13

GC content: 61.62

Gene sequence:

>951_bases
ATGGGAGTGGCGGCGCACCAACAGATCTACCGTCCAGTATCGGGACACGGGGGAGCGATGAGCTTGGGACTCGAGAAGCA
CCGCCGCAGCGTGGATATCGAACGTGGCCGCATCAGCTATCTCGACATCGGTGCCGGTTCACCGACGGTATTCGTTCACG
GGGTCCTCACCAACAGTCTGCTCTGGCGCGATGTCGTGACCGCCGTCGCGGCCACGGGACGGCGCTGCATCGCACTGGAT
CTGCCCGGTCACGGGCACTCGCCCGTTCCGGCGGATGGCATCGACGTCACACTGTCGGGGCTAGCCCAACTTATCGCGGA
ATTTCTGGACAGCATTGGGATTGACGAGTTCGACCTGGTAGCCAACGACACCGGGGGAGCGGTTGCGCAAATCATGGTTG
CCCGTCAACCGGACCGAATCAGAACCCTGGCGCTGACCAACTGTGACACCGAAGGCCATGTGCCTCCCAAACTGTTCAAA
CCGGTAGTGGCACTGGCCCGGCCACCGCTGATGGCCCTGATCGGCCCACGTCTGTTTGCGCGCCGCAAAGTGCTCAGAGC
GCTGTTAGGTGCCGGGTACCGTAAGCCCGGCCGCCTGCCGGATAGCATCGTGGAGTCATACGGACAGCCCGTGTTTGGAA
CCGCAGAGTCATCCCGTTTTCTGTCAAAGATGTTGCGGGCGATGCATACCCGAGACCTTGAAGCCGCACGTGCCGGCCTG
GTGACATTTACCAAACCGACGCTGATCGCCTGGGGTCTGGGCGACTACTTTTTTCCACTCAAGTACGGGCAGCGACTCGC
CGAACTTTTCGGTGGCCCAGTAACCTTCGAAACCGTACCGGACGGCCGACTGTACTTTCCCGATGAGGATGCAGACCGGC
TGCTGCCGCTGCTTTACAGACACTGGCACTCGGCGGGTCGGCAAGAGTCCTCCACAGAGGTGGGGAGTTGA

Upstream 100 bases:

>100_bases
TCCACATTGTCGACATGGACATGGCCAACGCCCGATTTCTGGGGCCCGCCGAGGCCGTACTGCTGTGCCTGACCAGTGCC
GCCCTGGCCACGCTCGGGAT

Downstream 100 bases:

>100_bases
CATGTTGGAGATGAAGCCGGGGTGTGAGAAATGTGGAACGCCGCTGAATCATGCCGCGGCCGCGTGGATTTGCAGTTACG
AATGCACGTTTTGCCCGCAT

Product: putative hydrolase, alpha/beta hydrolase fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGVAAHQQIYRPVSGHGGAMSLGLEKHRRSVDIERGRISYLDIGAGSPTVFVHGVLTNSLLWRDVVTAVAATGRRCIALD
LPGHGHSPVPADGIDVTLSGLAQLIAEFLDSIGIDEFDLVANDTGGAVAQIMVARQPDRIRTLALTNCDTEGHVPPKLFK
PVVALARPPLMALIGPRLFARRKVLRALLGAGYRKPGRLPDSIVESYGQPVFGTAESSRFLSKMLRAMHTRDLEAARAGL
VTFTKPTLIAWGLGDYFFPLKYGQRLAELFGGPVTFETVPDGRLYFPDEDADRLLPLLYRHWHSAGRQESSTEVGS

Sequences:

>Translated_316_residues
MGVAAHQQIYRPVSGHGGAMSLGLEKHRRSVDIERGRISYLDIGAGSPTVFVHGVLTNSLLWRDVVTAVAATGRRCIALD
LPGHGHSPVPADGIDVTLSGLAQLIAEFLDSIGIDEFDLVANDTGGAVAQIMVARQPDRIRTLALTNCDTEGHVPPKLFK
PVVALARPPLMALIGPRLFARRKVLRALLGAGYRKPGRLPDSIVESYGQPVFGTAESSRFLSKMLRAMHTRDLEAARAGL
VTFTKPTLIAWGLGDYFFPLKYGQRLAELFGGPVTFETVPDGRLYFPDEDADRLLPLLYRHWHSAGRQESSTEVGS
>Mature_315_residues
GVAAHQQIYRPVSGHGGAMSLGLEKHRRSVDIERGRISYLDIGAGSPTVFVHGVLTNSLLWRDVVTAVAATGRRCIALDL
PGHGHSPVPADGIDVTLSGLAQLIAEFLDSIGIDEFDLVANDTGGAVAQIMVARQPDRIRTLALTNCDTEGHVPPKLFKP
VVALARPPLMALIGPRLFARRKVLRALLGAGYRKPGRLPDSIVESYGQPVFGTAESSRFLSKMLRAMHTRDLEAARAGLV
TFTKPTLIAWGLGDYFFPLKYGQRLAELFGGPVTFETVPDGRLYFPDEDADRLLPLLYRHWHSAGRQESSTEVGS

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=113, Percent_Identity=28.3185840707965, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 34311; Mature: 34180

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVAAHQQIYRPVSGHGGAMSLGLEKHRRSVDIERGRISYLDIGAGSPTVFVHGVLTNSL
CCCCHHHHHHCCCCCCCCEEECCHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHH
LWRDVVTAVAATGRRCIALDLPGHGHSPVPADGIDVTLSGLAQLIAEFLDSIGIDEFDLV
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
ANDTGGAVAQIMVARQPDRIRTLALTNCDTEGHVPPKLFKPVVALARPPLMALIGPRLFA
ECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
RRKVLRALLGAGYRKPGRLPDSIVESYGQPVFGTAESSRFLSKMLRAMHTRDLEAARAGL
HHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCCHHHHHCCC
VTFTKPTLIAWGLGDYFFPLKYGQRLAELFGGPVTFETVPDGRLYFPDEDADRLLPLLYR
EEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHHHHHH
HWHSAGRQESSTEVGS
HHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GVAAHQQIYRPVSGHGGAMSLGLEKHRRSVDIERGRISYLDIGAGSPTVFVHGVLTNSL
CCCHHHHHHCCCCCCCCEEECCHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHH
LWRDVVTAVAATGRRCIALDLPGHGHSPVPADGIDVTLSGLAQLIAEFLDSIGIDEFDLV
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
ANDTGGAVAQIMVARQPDRIRTLALTNCDTEGHVPPKLFKPVVALARPPLMALIGPRLFA
ECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
RRKVLRALLGAGYRKPGRLPDSIVESYGQPVFGTAESSRFLSKMLRAMHTRDLEAARAGL
HHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCCHHHHHCCC
VTFTKPTLIAWGLGDYFFPLKYGQRLAELFGGPVTFETVPDGRLYFPDEDADRLLPLLYR
EEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHHHHHH
HWHSAGRQESSTEVGS
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]