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The map label for this gene is fadE12 [H]

Identifier: 169629151

GI number: 169629151

Start: 2062352

End: 2063506

Strand: Reverse

Name: fadE12 [H]

Synonym: MAB_2065c

Alternate gene names: 169629151

Gene position: 2063506-2062352 (Counterclockwise)

Preceding gene: 169629152

Following gene: 169629150

Centisome position: 40.72

GC content: 65.45

Gene sequence:

>1155_bases
ATGGAATTGCACGAGACAGAGGAACGTCAGGACCTGCGCAAGGCGGTCGCCGAGATCGCCAAGGACTTCGGACACGAGTA
CTACCTGGAAAAATCGCTGGCCGGCGCGAAGAGCACCGAGCTGTGGCAGGCCGTGGGCAAACAGGGCTTCCTCGGGGTGA
ACCTTTCCGAGCAGTACGGCGGCGGCGGCGGCGGCATCTACGACATGCAGATCGTCGGTGAGGAGCTCGCCGCGGCGGGC
TGCCCGCTGCTGATGACCGTCGTCTCGCCAACCATCTGCGGCACGATCATCCAGGCATTCGGCAGTGAGGAACTCAAGCA
GCAGTGGCTGCCGGGCATCGCCAGCGGCGAGACGATCATGGCATTCGCAATCACCGAGCCGGACGCGGGCTCGAACTCGC
ACAACATCTCCACGACCGCGAAACGCGACGGCGACGACTGGGTCATCAACGGCACCAAGTACTACATCTCCGGTGTCGAC
GAAGCCGAAGCGATCCTGGTCGTCACCCGAACGTCTACCAACGACAGTGGTCGCGGACTACTCAGCCTGCTCGTCGTGCC
CACCGATGTCCCCGGGCTCACCAAGTCACTCATCCCGGTCCAGGCGGTCACTCCAGAGAAGCAGTTCACTCTATTCTTCG
ATGACGTCCGCGTGCCGGCCGCCAACCTTATCGGCACGGAGAACGAGGGCCTGCGCCAGGTCTTCATGGGCCTGAACCCG
GAGCGAATCATGGGGGCAGCGCTCGGCAACGGCATCGGCCGTTACGCGCTGGATAAAGCCGCCGATTACGCCCGCAACCG
CCACGTGTGGGGAGCGCCGATCGGCTCGCACCAGGGCGTATCGCACCCCCTCGCCCACGCCAAGATCCAGGTCGAGCTGG
CCCGGTTGATGACCCAGCGTGCCGCCGCCCTGCACGACGCCGGCGATCCGGGGTCGGGTGAGGCGTCGAACATGGCGAAA
TATGCCGCAGCCGAGGCGGGCATCCTGGCGCTCGACCAGGCGATTCAGACCCACGGCGGCAACGGCATGGCCACCGAGTA
CGGCCTCGCCACGTTGTGGGGTCCGGCCCGGCTCATGCGCACCGCGCCGATCAGCCGCGAAATGATCCTCAACTTCGTGG
CGCAGCACAGCCTGAAACTGCCCGCGTCCTACTGA

Upstream 100 bases:

>100_bases
GGCGGTGGACGGCGGTGAAGTGGCGTCGGACGCCACCGAGCTCTAATGAACCCGGCGCGCTCCCGATCGGTGGCGCGTCG
ATACCGATGTGAGGAGTGTC

Downstream 100 bases:

>100_bases
GTCGCCGCGGACGGAAAGGGAATCGCATGCAACTCGGCATCGGTCAGTGGGTGACCCGGCGCGCCTTCCTCAACGGCGGG
CGCACCGCGTTGATCAGCAA

Product: acyl-CoA dehydrogenase FadE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTELWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAG
CPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVD
EAEAILVVTRTSTNDSGRGLLSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGTENEGLRQVFMGLNP
ERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVSHPLAHAKIQVELARLMTQRAAALHDAGDPGSGEASNMAK
YAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY

Sequences:

>Translated_384_residues
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTELWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAG
CPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVD
EAEAILVVTRTSTNDSGRGLLSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGTENEGLRQVFMGLNP
ERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVSHPLAHAKIQVELARLMTQRAAALHDAGDPGSGEASNMAK
YAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY
>Mature_384_residues
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTELWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAG
CPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVD
EAEAILVVTRTSTNDSGRGLLSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGTENEGLRQVFMGLNP
ERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVSHPLAHAKIQVELARLMTQRAAALHDAGDPGSGEASNMAK
YAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=370, Percent_Identity=31.8918918918919, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4557233, Length=341, Percent_Identity=35.1906158357771, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4501859, Length=341, Percent_Identity=31.6715542521994, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI226958412, Length=359, Percent_Identity=27.8551532033426, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=28.2722513089005, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=28.7878787878788, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4557231, Length=365, Percent_Identity=29.3150684931507, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI187960098, Length=365, Percent_Identity=29.3150684931507, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI38505218, Length=294, Percent_Identity=32.9931972789116, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI48976061, Length=317, Percent_Identity=28.7066246056782, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI211971008, Length=317, Percent_Identity=28.7066246056782, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI76496475, Length=353, Percent_Identity=28.328611898017, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4557235, Length=353, Percent_Identity=28.328611898017, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21361497, Length=356, Percent_Identity=24.1573033707865, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7669494, Length=322, Percent_Identity=27.639751552795, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503943, Length=321, Percent_Identity=27.4143302180685, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=26.6318537859008, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=25.2631578947368, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87081702, Length=368, Percent_Identity=24.1847826086957, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=371, Percent_Identity=32.6145552560647, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17534899, Length=392, Percent_Identity=30.3571428571429, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17569725, Length=395, Percent_Identity=28.8607594936709, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17508101, Length=333, Percent_Identity=28.5285285285285, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=28, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17538396, Length=327, Percent_Identity=30.2752293577982, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17505929, Length=337, Percent_Identity=29.080118694362, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71990804, Length=285, Percent_Identity=30.1754385964912, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=25.3369272237197, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=338, Percent_Identity=27.810650887574, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=275, Percent_Identity=29.0909090909091, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=226, Percent_Identity=29.646017699115, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=282, Percent_Identity=26.241134751773, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=24.8175182481752, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=338, Percent_Identity=26.3313609467456, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=194, Percent_Identity=27.319587628866, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646207, Length=337, Percent_Identity=32.9376854599407, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=31.2335958005249, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666513, Length=361, Percent_Identity=30.1939058171745, Blast_Score=147, Evalue=9e-36,
Organism=Drosophila melanogaster, GI21355753, Length=385, Percent_Identity=30.3896103896104, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=31.6939890710383, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281363737, Length=366, Percent_Identity=26.775956284153, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI19920834, Length=331, Percent_Identity=27.7945619335347, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40902; Mature: 40902

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTELWQAVGKQGFLGVNLSEQYG
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCHHHCC
GGGGGIYDMQIVGEELAAAGCPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIM
CCCCCEEEHEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEE
AFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVDEAEAILVVTRTSTNDSGRGL
EEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEEEECCCCCCCCCE
LSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGTENEGLRQVFMGLNP
EEEEEECCCCCCCHHHCCCEEEECCCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHCCCH
ERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVSHPLAHAKIQVELARLMTQR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AAALHDAGDPGSGEASNMAKYAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMR
HHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCHHHHCCHHHHHH
TAPISREMILNFVAQHSLKLPASY
CCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTELWQAVGKQGFLGVNLSEQYG
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCHHHCC
GGGGGIYDMQIVGEELAAAGCPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIM
CCCCCEEEHEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEE
AFAITEPDAGSNSHNISTTAKRDGDDWVINGTKYYISGVDEAEAILVVTRTSTNDSGRGL
EEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCCCEEEEEEECCCCCCCCCE
LSLLVVPTDVPGLTKSLIPVQAVTPEKQFTLFFDDVRVPAANLIGTENEGLRQVFMGLNP
EEEEEECCCCCCCHHHCCCEEEECCCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHCCCH
ERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVSHPLAHAKIQVELARLMTQR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AAALHDAGDPGSGEASNMAKYAAAEAGILALDQAIQTHGGNGMATEYGLATLWGPARLMR
HHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCHHHHCCHHHHHH
TAPISREMILNFVAQHSLKLPASY
CCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]