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The map label for this gene is cobT [H]

Identifier: 169629040

GI number: 169629040

Start: 1952138

End: 1953160

Strand: Reverse

Name: cobT [H]

Synonym: MAB_1953c

Alternate gene names: 169629040

Gene position: 1953160-1952138 (Counterclockwise)

Preceding gene: 169629041

Following gene: 169629039

Centisome position: 38.55

GC content: 70.97

Gene sequence:

>1023_bases
GTGACACAGGCCGAACCACCAGAGGCGCCGCGATTCGCGCCGGTATCGGCACCCGATCCGGGTATCGCCGACGCCGCACG
CGCACGCCAGCACCGACTCACCAAGCCCACCGGCGCGTTGGGCCGGCTGGAAGAGCTGTCGGTGTGGGCGGCAGCCTGCC
AGAATCGTTGCCCCCCTACGACATTCCAGCGACCACGGGTTGTCGTGTTCGCCGGCGACCACGGCGTGGCCGCCGCTGGC
GTATCCGCCTATCCTGCGTCGGTCACCGCCCAGATGGTGCGTAACATGGACGCCGGTGGCGCCGCGGTCAACGTACTGGC
GGCTTTGACCGGAGCGGGTGTGCGTGTGGCCGATATGGCAGTCGGCCGGCCCAGCGGAAACATCGCGGTCGAGGACGCAC
TCACCGGCGAGCAGACGCACGCGGCGCTCGCGGCGGGCATCGCACTGGCCGACGCCGAGGTGGACGGTGGTGCCGACCTC
CTCATTGCCGGCGATATGGGCATCGGGAACACCACGCCCGCAACGGTATTGGTGGCTGCGCTGACGGGCAGCGAGCCGGT
GGCGGTGGTGGGCCGCGGCACCGGGGTCGACGACGCCGGATGGATGCGCAAGACCGCCGCAGTCCGTGACGCGCTGCGCC
GCACCAAGGATGTACGTACGGATCCGGTTGCGCTGCTGGGTGTGGCCGGCGGCGCCGATCTCGCCGCCATGACCGGTTTC
CTGGCGCAGGCGGCAGTGCGGCGCACACCCGTATTGCTGGACGGACTGGTGGTCACCTCCGCCGCGCTGGTGGCCGAGCA
GCTGGCACCCGGAGCGCGCCAGTGGTGGCTTGCGGGACACCGATCTACCGAACCGGCGCATTCCCTCGCCCTGCAACGCC
TGCGGCTGGACCCGGTGCTCGATCTGCAGATGCGATTGGGCGAGGGCTCCGGCGCGCTGGTGGCGCTGCCGGTGCTACAG
GCCGCGGTCGGCACGCTCGCTCAGATGGCGACCTTCGATGAGGCCCGGGTGGACACCGCGTGA

Upstream 100 bases:

>100_bases
CGGATGCACTCGGAGCCCTGAATCAGGCGGTCGCGGCGCGCGCCGATCGGGTGCTGCTGGTGGTGGCGGGTCAGCCGCTG
ACCATCAAGGGGGGACGCTC

Downstream 100 bases:

>100_bases
ATGCCCTGCTGCGAATCCTGCGGCCGGTGGGCGGCGCCTTCGAATTCGCCACCGTGGCACCGGTTCCGGCCCGGCTGGCT
GGCACGCTTTCCGGCCCGGT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTQAEPPEAPRFAPVSAPDPGIADAARARQHRLTKPTGALGRLEELSVWAAACQNRCPPTTFQRPRVVVFAGDHGVAAAG
VSAYPASVTAQMVRNMDAGGAAVNVLAALTGAGVRVADMAVGRPSGNIAVEDALTGEQTHAALAAGIALADAEVDGGADL
LIAGDMGIGNTTPATVLVAALTGSEPVAVVGRGTGVDDAGWMRKTAAVRDALRRTKDVRTDPVALLGVAGGADLAAMTGF
LAQAAVRRTPVLLDGLVVTSAALVAEQLAPGARQWWLAGHRSTEPAHSLALQRLRLDPVLDLQMRLGEGSGALVALPVLQ
AAVGTLAQMATFDEARVDTA

Sequences:

>Translated_340_residues
MTQAEPPEAPRFAPVSAPDPGIADAARARQHRLTKPTGALGRLEELSVWAAACQNRCPPTTFQRPRVVVFAGDHGVAAAG
VSAYPASVTAQMVRNMDAGGAAVNVLAALTGAGVRVADMAVGRPSGNIAVEDALTGEQTHAALAAGIALADAEVDGGADL
LIAGDMGIGNTTPATVLVAALTGSEPVAVVGRGTGVDDAGWMRKTAAVRDALRRTKDVRTDPVALLGVAGGADLAAMTGF
LAQAAVRRTPVLLDGLVVTSAALVAEQLAPGARQWWLAGHRSTEPAHSLALQRLRLDPVLDLQMRLGEGSGALVALPVLQ
AAVGTLAQMATFDEARVDTA
>Mature_339_residues
TQAEPPEAPRFAPVSAPDPGIADAARARQHRLTKPTGALGRLEELSVWAAACQNRCPPTTFQRPRVVVFAGDHGVAAAGV
SAYPASVTAQMVRNMDAGGAAVNVLAALTGAGVRVADMAVGRPSGNIAVEDALTGEQTHAALAAGIALADAEVDGGADLL
IAGDMGIGNTTPATVLVAALTGSEPVAVVGRGTGVDDAGWMRKTAAVRDALRRTKDVRTDPVALLGVAGGADLAAMTGFL
AQAAVRRTPVLLDGLVVTSAALVAEQLAPGARQWWLAGHRSTEPAHSLALQRLRLDPVLDLQMRLGEGSGALVALPVLQA
AVGTLAQMATFDEARVDTA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=336, Percent_Identity=34.8214285714286, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 34534; Mature: 34403

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAEPPEAPRFAPVSAPDPGIADAARARQHRLTKPTGALGRLEELSVWAAACQNRCPPT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TFQRPRVVVFAGDHGVAAAGVSAYPASVTAQMVRNMDAGGAAVNVLAALTGAGVRVADMA
CCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEHEE
VGRPSGNIAVEDALTGEQTHAALAAGIALADAEVDGGADLLIAGDMGIGNTTPATVLVAA
CCCCCCCEEEECCCCCCHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCCCHHHEEEEE
LTGSEPVAVVGRGTGVDDAGWMRKTAAVRDALRRTKDVRTDPVALLGVAGGADLAAMTGF
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
LAQAAVRRTPVLLDGLVVTSAALVAEQLAPGARQWWLAGHRSTEPAHSLALQRLRLDPVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCCHHHHHHHHHHCCCCCE
DLQMRLGEGSGALVALPVLQAAVGTLAQMATFDEARVDTA
EHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQAEPPEAPRFAPVSAPDPGIADAARARQHRLTKPTGALGRLEELSVWAAACQNRCPPT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TFQRPRVVVFAGDHGVAAAGVSAYPASVTAQMVRNMDAGGAAVNVLAALTGAGVRVADMA
CCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEHEE
VGRPSGNIAVEDALTGEQTHAALAAGIALADAEVDGGADLLIAGDMGIGNTTPATVLVAA
CCCCCCCEEEECCCCCCHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCCCHHHEEEEE
LTGSEPVAVVGRGTGVDDAGWMRKTAAVRDALRRTKDVRTDPVALLGVAGGADLAAMTGF
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
LAQAAVRRTPVLLDGLVVTSAALVAEQLAPGARQWWLAGHRSTEPAHSLALQRLRLDPVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCCCCHHHHHHHHHHCCCCCE
DLQMRLGEGSGALVALPVLQAAVGTLAQMATFDEARVDTA
EHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA