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The map label for this gene is glnA [H]

Identifier: 169629021

GI number: 169629021

Start: 1932319

End: 1933755

Strand: Reverse

Name: glnA [H]

Synonym: MAB_1933c

Alternate gene names: 169629021

Gene position: 1933755-1932319 (Counterclockwise)

Preceding gene: 169629026

Following gene: 169629020

Centisome position: 38.16

GC content: 63.4

Gene sequence:

>1437_bases
ATGGCGTTCAGTAGCCCCGACGAGGTATTCAAGTTCATTGCCGACGAGAAGGTCGAGTACGTGGACGTCAGGTTCTGTGA
CCTGCCGGGCGTCGTGCAGCACTTCTCGATCCCGGCTTCGGCCTTCGATCAGAGCGTTTTCGACGACGGCCTGGCGTTCG
ACGGTTCCTCGGTCCGTGGTTTCCAGTCGATCCACGAATCGGACATGCTCCTGCTCCCCGACATCTCGACCGCGCGCGTC
GACCCTTTCCGCGCCGCCAAGACGCTGAACATCAACTTCTTCGTGCACGACCCGTTCACCCGCGAGGCCTACTCGCGTGA
CCCTCGCAATGTCGCCCGCAAGGCCGAGCAGTACCTGGCCAGCACCGGCATCGCCGACACCTGCTACTTCGGCGCCGAGG
CCGAGTTCTACATCTTCGACTCGGTGACCTTCGATTCCAAGATGAACGGCACCTTCTACGAGATCGACTCGGAGTCGGGC
TGGTGGAACACCGGAGAGCCCTACGAGGAGGACGGTAGCCCGAACCGCGGCTACAAGGTCCGCCCCAAGGGCGGCTACTT
CCCGGTGGCCCCCTACGACCACTACGTCGACCTGCGCGACGAGATGTCGACCAACCTGATCAACGCCGGGTTCACCCTGG
AGCGCGGCCACCACGAGGTGGGCACCGCCGGCCAGGCCGAGATCAACTACAAGTTCGACACGCTGCTGGCCGCGGCCGAC
GACGTGCTGCTGTTCAAATACATCATCAAGAACACCGCCTGGGCCAACGGCAAGACTGTCACCTTCATGCCCAAGCCGCT
GTTCGGTGACAACGGCTCCGGCATGCACGCGCACCAGTCGCTGTGGAAGGACGGCAAGCCCCTGTTCCACGATGAGGCCG
GTTACGCCGGGCTGTCGGACCTGGCCCGCCACTACATCGGCGGCATCCTGCACCACGCCCCGTCGCTGCTGGCGTTCACC
AACCCGACGGTGAACTCCTACAAGCGTCTGGTGCCGGGCTACGAGGCCCCGATCAACCTGGTGTACAGCCAGCGCAACCG
CTCCGCGTGCGTGCGCATCCCGATCACCGGCAATAACCCGAAGGCCAAGCGTCTCGAGTTCCGTTGCCCGGACAGCTCGG
GTAACCCGTACCTGGCGTTCGCGGCCATGCTGATGGCAGGCATCGACGGCATCAAGAACAAGATCGAGCCGCTGGCCCCG
GTCGACAAGGACCTGTACGAGCTGCCTCCCGAGGAGGCCGCCGGTATTCCGCAGGCCCCGACCAGCCTCGCCACGGTGAT
CGACAACCTCGAGAAGGATCACGAATACCTCACCGAGGGTGGCGTTTTCACTTCCGACTTGATCGAGACCTGGATCTCGT
ACAAGCGCGAGAACGAGATCGAGCCGGTCAACATCCGGCCTCACCCGTACGAGTTCGCGCTTTACTACGACGTGTAA

Upstream 100 bases:

>100_bases
CATCCGCGCAACATATGGTTGACCGGCGGGCAACACCGGCTCCATAGGTTCGCATCGCGCGGTCATTATCCGTGGCACAA
GAGGGAAAACAAGGAGAAGC

Downstream 100 bases:

>100_bases
ATCGGCTCTAGGACAAGGCCCCCGGGAAAGCCTCCCGGGGGCCTTGTCATTTTCTGACTCACGGCACGGAATACCGCGGG
TCGGCGTAGGTTGAAAGTAG

Product: glutamine synthetase, type I (GlnA1)

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MAFSSPDEVFKFIADEKVEYVDVRFCDLPGVVQHFSIPASAFDQSVFDDGLAFDGSSVRGFQSIHESDMLLLPDISTARV
DPFRAAKTLNINFFVHDPFTREAYSRDPRNVARKAEQYLASTGIADTCYFGAEAEFYIFDSVTFDSKMNGTFYEIDSESG
WWNTGEPYEEDGSPNRGYKVRPKGGYFPVAPYDHYVDLRDEMSTNLINAGFTLERGHHEVGTAGQAEINYKFDTLLAAAD
DVLLFKYIIKNTAWANGKTVTFMPKPLFGDNGSGMHAHQSLWKDGKPLFHDEAGYAGLSDLARHYIGGILHHAPSLLAFT
NPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGNNPKAKRLEFRCPDSSGNPYLAFAAMLMAGIDGIKNKIEPLAP
VDKDLYELPPEEAAGIPQAPTSLATVIDNLEKDHEYLTEGGVFTSDLIETWISYKRENEIEPVNIRPHPYEFALYYDV

Sequences:

>Translated_478_residues
MAFSSPDEVFKFIADEKVEYVDVRFCDLPGVVQHFSIPASAFDQSVFDDGLAFDGSSVRGFQSIHESDMLLLPDISTARV
DPFRAAKTLNINFFVHDPFTREAYSRDPRNVARKAEQYLASTGIADTCYFGAEAEFYIFDSVTFDSKMNGTFYEIDSESG
WWNTGEPYEEDGSPNRGYKVRPKGGYFPVAPYDHYVDLRDEMSTNLINAGFTLERGHHEVGTAGQAEINYKFDTLLAAAD
DVLLFKYIIKNTAWANGKTVTFMPKPLFGDNGSGMHAHQSLWKDGKPLFHDEAGYAGLSDLARHYIGGILHHAPSLLAFT
NPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGNNPKAKRLEFRCPDSSGNPYLAFAAMLMAGIDGIKNKIEPLAP
VDKDLYELPPEEAAGIPQAPTSLATVIDNLEKDHEYLTEGGVFTSDLIETWISYKRENEIEPVNIRPHPYEFALYYDV
>Mature_477_residues
AFSSPDEVFKFIADEKVEYVDVRFCDLPGVVQHFSIPASAFDQSVFDDGLAFDGSSVRGFQSIHESDMLLLPDISTARVD
PFRAAKTLNINFFVHDPFTREAYSRDPRNVARKAEQYLASTGIADTCYFGAEAEFYIFDSVTFDSKMNGTFYEIDSESGW
WNTGEPYEEDGSPNRGYKVRPKGGYFPVAPYDHYVDLRDEMSTNLINAGFTLERGHHEVGTAGQAEINYKFDTLLAAADD
VLLFKYIIKNTAWANGKTVTFMPKPLFGDNGSGMHAHQSLWKDGKPLFHDEAGYAGLSDLARHYIGGILHHAPSLLAFTN
PTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGNNPKAKRLEFRCPDSSGNPYLAFAAMLMAGIDGIKNKIEPLAPV
DKDLYELPPEEAAGIPQAPTSLATVIDNLEKDHEYLTEGGVFTSDLIETWISYKRENEIEPVNIRPHPYEFALYYDV

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=503, Percent_Identity=23.2604373757455, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI1790301, Length=474, Percent_Identity=50.8438818565401, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI87081870, Length=395, Percent_Identity=27.5949367088608, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 53471; Mature: 53340

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSSPDEVFKFIADEKVEYVDVRFCDLPGVVQHFSIPASAFDQSVFDDGLAFDGSSVRG
CCCCCHHHHHHHHHCCCEEEEEEEEECCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCHH
FQSIHESDMLLLPDISTARVDPFRAAKTLNINFFVHDPFTREAYSRDPRNVARKAEQYLA
HHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHCCCHHHHHHHHHHHHH
STGIADTCYFGAEAEFYIFDSVTFDSKMNGTFYEIDSESGWWNTGEPYEEDGSPNRGYKV
HCCCCHHEEECCCEEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
RPKGGYFPVAPYDHYVDLRDEMSTNLINAGFTLERGHHEVGTAGQAEINYKFDTLLAAAD
CCCCCCCCCCCCCHHCCCHHHHHHHEEECCEEEECCCCCCCCCCCEEEEEEHHHHHHHHH
DVLLFKYIIKNTAWANGKTVTFMPKPLFGDNGSGMHAHQSLWKDGKPLFHDEAGYAGLSD
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCHHH
LARHYIGGILHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGNNP
HHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCCC
KAKRLEFRCPDSSGNPYLAFAAMLMAGIDGIKNKIEPLAPVDKDLYELPPEEAAGIPQAP
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHCCCCCCC
TSLATVIDNLEKDHEYLTEGGVFTSDLIETWISYKRENEIEPVNIRPHPYEFALYYDV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEEEC
>Mature Secondary Structure 
AFSSPDEVFKFIADEKVEYVDVRFCDLPGVVQHFSIPASAFDQSVFDDGLAFDGSSVRG
CCCCHHHHHHHHHCCCEEEEEEEEECCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCHH
FQSIHESDMLLLPDISTARVDPFRAAKTLNINFFVHDPFTREAYSRDPRNVARKAEQYLA
HHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHCCCHHHHHHHHHHHHH
STGIADTCYFGAEAEFYIFDSVTFDSKMNGTFYEIDSESGWWNTGEPYEEDGSPNRGYKV
HCCCCHHEEECCCEEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
RPKGGYFPVAPYDHYVDLRDEMSTNLINAGFTLERGHHEVGTAGQAEINYKFDTLLAAAD
CCCCCCCCCCCCCHHCCCHHHHHHHEEECCEEEECCCCCCCCCCCEEEEEEHHHHHHHHH
DVLLFKYIIKNTAWANGKTVTFMPKPLFGDNGSGMHAHQSLWKDGKPLFHDEAGYAGLSD
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCHHH
LARHYIGGILHHAPSLLAFTNPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGNNP
HHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCCC
KAKRLEFRCPDSSGNPYLAFAAMLMAGIDGIKNKIEPLAPVDKDLYELPPEEAAGIPQAP
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHCCCCCCC
TSLATVIDNLEKDHEYLTEGGVFTSDLIETWISYKRENEIEPVNIRPHPYEFALYYDV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA