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The map label for this gene is desA3 [H]

Identifier: 169628677

GI number: 169628677

Start: 1615581

End: 1616792

Strand: Reverse

Name: desA3 [H]

Synonym: MAB_1587c

Alternate gene names: 169628677

Gene position: 1616792-1615581 (Counterclockwise)

Preceding gene: 169628678

Following gene: 169628676

Centisome position: 31.91

GC content: 61.88

Gene sequence:

>1212_bases
ATGACCAGCAACGAAATCACCATCAGCGCAGCGGATATCGAAGCGCTGGGCAAGGACCTCGATGAATTGCGCGACCGTAT
CGTCGCCGACTTGGGCGATCGCGACCGCGAGTACATCTACTCGATCATCAAGACACAGCGCGGCTGCGAGGTCGCCGGGC
GGGCCCTGATGTACTTGGGATTCATCCCGCCGGTGTGGCTCGCCGCCGTGGGCGCCCTGTCCGTCTCCAAGATCCTGGAC
AACATGGAGATCGGCCACAATGTAATGCACGGCCAGTACGACTGGATGCGCGAAAAGGGCCTCAACTCACGCGAGTTCGA
ATGGGACACGGTGTGCCCCGCCGACCAGTGGCGGCACTCGCACAACTACATGCACCACACCTACACCAACATCGTCGACA
TGGACCGCGACGTGGGTTACGGCATCCTGCGCATGGCACCCGAACAGAAGTGGAACCCCTACTACCTGGGCAATCTGGCC
TGGGCAACCGCGCTGATGGTGTTCTTCGAGTGGGGCGTCATGGTGCACGAGCTCGAGGCCGAGAACATCGTAAGGGGCAA
GCGCAAGTGGTACGACCTCAAACCGCTGATCAAAGGCATGTGGCGTAAGGCCAGTAAACAAGTTCTCAAGGACTACGTGA
TCTTCCCCGCGCTCACCGGGCCGCTGTTCCCGATCACCTTCCTGGGCAACATGTCTGCCAACTTCGTGCGCAATCTGTGG
ACGTTCTCGATCATCTTCTGCGGGCACTTCCCGTCCGGCACCCAGACCTTCTCCAAGGAGGAAACCGCCAACGAGACGCG
GGGCGAATGGTATCTGCGGCAGTTGCTCGGCTCGGCGAACATCGAGGGCGGCAGGCTCTTTCACATCATGAGCGGCAACC
TGTCCCACCAGATCGAGCACCATTTGTTCCCCGATCTGCCGGCGAACCGCTACCCGGAGATGGCCACCGAGGTGCGCGAG
CTGTGCCAGAAGTACGGTCTGCCCTACAACACGGGCGGCTTGTTCGCCCAGCTCTCATCGACCTGGAAGAAGATCGCCCG
CCTGTCGCTGCCCAACGGCTGGTTCCGCGGTGATGACCAGCTCGTGGTCCACATCGAACGGAACAAGCACAAGGAAGCGG
CCACCACCCCGGAGCCCGAGGTCATCGTCGTTGACGAGCGCGGCAACGTGATGTCCCCGGCCAGCGGCGCCGGCGAGCTG
GTGGACGCGTAA

Upstream 100 bases:

>100_bases
CCGGCGATGAGAACGACGATCCCGATCAACATATCCAGCTCTGCATCACCGCGCCCGTCGGTGACGTCTCGATCAACCTC
TAGACCCCAGGAGATAGACG

Downstream 100 bases:

>100_bases
GTTAGGGGACGTGGTGAGCAAGTTCGAACGCAACAAGGACCTGGCCCAAGAGGTCGTGTCGTCCGCCGCCGAGCATGTCG
GTGAGATCGCCAAGATCATC

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(9)-desaturase; Stearoyl-CoA desaturase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTSNEITISAADIEALGKDLDELRDRIVADLGDRDREYIYSIIKTQRGCEVAGRALMYLGFIPPVWLAAVGALSVSKILD
NMEIGHNVMHGQYDWMREKGLNSREFEWDTVCPADQWRHSHNYMHHTYTNIVDMDRDVGYGILRMAPEQKWNPYYLGNLA
WATALMVFFEWGVMVHELEAENIVRGKRKWYDLKPLIKGMWRKASKQVLKDYVIFPALTGPLFPITFLGNMSANFVRNLW
TFSIIFCGHFPSGTQTFSKEETANETRGEWYLRQLLGSANIEGGRLFHIMSGNLSHQIEHHLFPDLPANRYPEMATEVRE
LCQKYGLPYNTGGLFAQLSSTWKKIARLSLPNGWFRGDDQLVVHIERNKHKEAATTPEPEVIVVDERGNVMSPASGAGEL
VDA

Sequences:

>Translated_403_residues
MTSNEITISAADIEALGKDLDELRDRIVADLGDRDREYIYSIIKTQRGCEVAGRALMYLGFIPPVWLAAVGALSVSKILD
NMEIGHNVMHGQYDWMREKGLNSREFEWDTVCPADQWRHSHNYMHHTYTNIVDMDRDVGYGILRMAPEQKWNPYYLGNLA
WATALMVFFEWGVMVHELEAENIVRGKRKWYDLKPLIKGMWRKASKQVLKDYVIFPALTGPLFPITFLGNMSANFVRNLW
TFSIIFCGHFPSGTQTFSKEETANETRGEWYLRQLLGSANIEGGRLFHIMSGNLSHQIEHHLFPDLPANRYPEMATEVRE
LCQKYGLPYNTGGLFAQLSSTWKKIARLSLPNGWFRGDDQLVVHIERNKHKEAATTPEPEVIVVDERGNVMSPASGAGEL
VDA
>Mature_402_residues
TSNEITISAADIEALGKDLDELRDRIVADLGDRDREYIYSIIKTQRGCEVAGRALMYLGFIPPVWLAAVGALSVSKILDN
MEIGHNVMHGQYDWMREKGLNSREFEWDTVCPADQWRHSHNYMHHTYTNIVDMDRDVGYGILRMAPEQKWNPYYLGNLAW
ATALMVFFEWGVMVHELEAENIVRGKRKWYDLKPLIKGMWRKASKQVLKDYVIFPALTGPLFPITFLGNMSANFVRNLWT
FSIIFCGHFPSGTQTFSKEETANETRGEWYLRQLLGSANIEGGRLFHIMSGNLSHQIEHHLFPDLPANRYPEMATEVREL
CQKYGLPYNTGGLFAQLSSTWKKIARLSLPNGWFRGDDQLVVHIERNKHKEAATTPEPEVIVVDERGNVMSPASGAGELV
DA

Specific function: Desaturates stearoyl-CoA to form oleoyl-CoA [H]

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable). Note=Has been shown to be membrane-associated but no reliable trans-membrane regions are predicted by bioinformatics tools [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Homo sapiens, GI214831730, Length=246, Percent_Identity=24.7967479674797, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 46030; Mature: 45899

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNEITISAADIEALGKDLDELRDRIVADLGDRDREYIYSIIKTQRGCEVAGRALMYLG
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
FIPPVWLAAVGALSVSKILDNMEIGHNVMHGQYDWMREKGLNSREFEWDTVCPADQWRHS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHH
HNYMHHTYTNIVDMDRDVGYGILRMAPEQKWNPYYLGNLAWATALMVFFEWGVMVHELEA
CCCHHHHHHHHHHCCCCCCCHHEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCH
ENIVRGKRKWYDLKPLIKGMWRKASKQVLKDYVIFPALTGPLFPITFLGNMSANFVRNLW
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHH
TFSIIFCGHFPSGTQTFSKEETANETRGEWYLRQLLGSANIEGGRLFHIMSGNLSHQIEH
HEEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHH
HLFPDLPANRYPEMATEVRELCQKYGLPYNTGGLFAQLSSTWKKIARLSLPNGWFRGDDQ
HCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LVVHIERNKHKEAATTPEPEVIVVDERGNVMSPASGAGELVDA
EEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSNEITISAADIEALGKDLDELRDRIVADLGDRDREYIYSIIKTQRGCEVAGRALMYLG
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
FIPPVWLAAVGALSVSKILDNMEIGHNVMHGQYDWMREKGLNSREFEWDTVCPADQWRHS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHH
HNYMHHTYTNIVDMDRDVGYGILRMAPEQKWNPYYLGNLAWATALMVFFEWGVMVHELEA
CCCHHHHHHHHHHCCCCCCCHHEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCH
ENIVRGKRKWYDLKPLIKGMWRKASKQVLKDYVIFPALTGPLFPITFLGNMSANFVRNLW
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHH
TFSIIFCGHFPSGTQTFSKEETANETRGEWYLRQLLGSANIEGGRLFHIMSGNLSHQIEH
HEEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHH
HLFPDLPANRYPEMATEVRELCQKYGLPYNTGGLFAQLSSTWKKIARLSLPNGWFRGDDQ
HCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LVVHIERNKHKEAATTPEPEVIVVDERGNVMSPASGAGELVDA
EEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]