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The map label for this gene is hmp [C]

Identifier: 169628678

GI number: 169628678

Start: 1616810

End: 1617901

Strand: Reverse

Name: hmp [C]

Synonym: MAB_1588c

Alternate gene names: 169628678

Gene position: 1617901-1616810 (Counterclockwise)

Preceding gene: 169628680

Following gene: 169628677

Centisome position: 31.93

GC content: 66.39

Gene sequence:

>1092_bases
ATGACATTTCTAACTAAAGCCACCCGGCGCATCCTCACCCCCGACTCGTCGCTGGGCAGGCTGCTGACAGCCGCCCTGAC
CCCGCACGCCGTTGACCGCTACCTCGAGCTGGTCGACCCGATGATCACCTGGGAAGAGGCTCGCGCCCGCGTTATCCGCG
TGCAGCGCCGTACCACCCGGTCGGTGACCCTGACGTTGCGCACAACACACCAGTTCAAAGGCTTTCACGCAGGTCAGTTC
GTACAACTGGGCGTCGTGATCGACGGTGTGCGGCACGTCCGCTGCTTCTCCCCGTCCTGTGCCGACGACGCCAGGGAGAT
CATCGAGCTGACCATCGCGCGCCGTCCCGATGGTCTCGTCTCGAACTACCTTTACAAGCACGCCGCCGTGGGGGACGTGT
ACAGCATCACCCCCGCCGCGGGCACGTTCGTCCTACCCGCACCCCGGCCCATCCGCACGCTCCTGATCGCAGCCGGAAGT
GGGATTACACCCGTGCTCTCAATGGCAAGAACACTCGTCGGCAATGGCTACCCGGGACAGCTCGCCGTGCTCTACTACGC
GCCGACTGCCGCGGATAACGCCTACGCCGGTGAACTGGCCGCTCTCGGGGAGGTGCCGTCGGTGACGGTGCGGGTGGAGT
ACACCCGCGACGGCGGGCAACACTTCAGCGCCGAACAGCTGCAGGCCGTCGCACCCTGGCATGCCGACGCGCAGACCTTC
CTGTGCGGGCCGCCGTCATTGCACGAGGCGGTCAGCGCGCTATACGCCGAACGCGGACTCTCCGACCGTCTGCACACCGA
GGAATTCACCCTCGCCACCGCGGGCAACACCGGCGAGGCCGGGGGCGTGCTGCGCTTCGCGACATCGGGCATCACCGCCG
AGAACGACGGACGACCGATCCTCGAACAGGCCGAGGCGGCCGGCCTGCAGCCCGAATTCGGCTGCCGGATGGGAATCTGC
TTCGCCTGCACCGCGGTGAAGACATCCGGGTGCACCCGCAACCTGCGCACCGGCGATGAGAACGACGATCCCGATCAACA
TATCCAGCTCTGCATCACCGCGCCCGTCGGTGACGTCTCGATCAACCTCTAG

Upstream 100 bases:

>100_bases
TCGCTGTGATGACCGACACGGTGATTACGGCTTGACTGAGTGGGGGCATATTGGTTCACAATTTCAGTGTACATTCGTTA
ACCTAACGGAGGGAGTTCGA

Downstream 100 bases:

>100_bases
ACCCCAGGAGATAGACGATGACCAGCAACGAAATCACCATCAGCGCAGCGGATATCGAAGCGCTGGGCAAGGACCTCGAT
GAATTGCGCGACCGTATCGT

Product: putative oxidoreductase

Products: @TETR01txt*tetrahydropteridine!; NO3-; NAD(P); Proton [C]

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTFLTKATRRILTPDSSLGRLLTAALTPHAVDRYLELVDPMITWEEARARVIRVQRRTTRSVTLTLRTTHQFKGFHAGQF
VQLGVVIDGVRHVRCFSPSCADDAREIIELTIARRPDGLVSNYLYKHAAVGDVYSITPAAGTFVLPAPRPIRTLLIAAGS
GITPVLSMARTLVGNGYPGQLAVLYYAPTAADNAYAGELAALGEVPSVTVRVEYTRDGGQHFSAEQLQAVAPWHADAQTF
LCGPPSLHEAVSALYAERGLSDRLHTEEFTLATAGNTGEAGGVLRFATSGITAENDGRPILEQAEAAGLQPEFGCRMGIC
FACTAVKTSGCTRNLRTGDENDDPDQHIQLCITAPVGDVSINL

Sequences:

>Translated_363_residues
MTFLTKATRRILTPDSSLGRLLTAALTPHAVDRYLELVDPMITWEEARARVIRVQRRTTRSVTLTLRTTHQFKGFHAGQF
VQLGVVIDGVRHVRCFSPSCADDAREIIELTIARRPDGLVSNYLYKHAAVGDVYSITPAAGTFVLPAPRPIRTLLIAAGS
GITPVLSMARTLVGNGYPGQLAVLYYAPTAADNAYAGELAALGEVPSVTVRVEYTRDGGQHFSAEQLQAVAPWHADAQTF
LCGPPSLHEAVSALYAERGLSDRLHTEEFTLATAGNTGEAGGVLRFATSGITAENDGRPILEQAEAAGLQPEFGCRMGIC
FACTAVKTSGCTRNLRTGDENDDPDQHIQLCITAPVGDVSINL
>Mature_362_residues
TFLTKATRRILTPDSSLGRLLTAALTPHAVDRYLELVDPMITWEEARARVIRVQRRTTRSVTLTLRTTHQFKGFHAGQFV
QLGVVIDGVRHVRCFSPSCADDAREIIELTIARRPDGLVSNYLYKHAAVGDVYSITPAAGTFVLPAPRPIRTLLIAAGSG
ITPVLSMARTLVGNGYPGQLAVLYYAPTAADNAYAGELAALGEVPSVTVRVEYTRDGGQHFSAEQLQAVAPWHADAQTFL
CGPPSLHEAVSALYAERGLSDRLHTEEFTLATAGNTGEAGGVLRFATSGITAENDGRPILEQAEAAGLQPEFGCRMGICF
ACTAVKTSGCTRNLRTGDENDDPDQHIQLCITAPVGDVSINL

Specific function: This is an electron transfer partner for desA3 [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=246, Percent_Identity=27.6422764227642, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787098, Length=327, Percent_Identity=26.2996941896024, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.5.1.34 [C]

Molecular weight: Translated: 39001; Mature: 38870

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLTKATRRILTPDSSLGRLLTAALTPHAVDRYLELVDPMITWEEARARVIRVQRRTTR
CCCHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
SVTLTLRTTHQFKGFHAGQFVQLGVVIDGVRHVRCFSPSCADDAREIIELTIARRPDGLV
EEEEEEEECHHCCCCCCCCEEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHH
SNYLYKHAAVGDVYSITPAAGTFVLPAPRPIRTLLIAAGSGITPVLSMARTLVGNGYPGQ
HHHHHHHHCCCCEEEECCCCCEEEECCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCCCC
LAVLYYAPTAADNAYAGELAALGEVPSVTVRVEYTRDGGQHFSAEQLQAVAPWHADAQTF
EEEEEEECCCCCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCCCCEE
LCGPPSLHEAVSALYAERGLSDRLHTEEFTLATAGNTGEAGGVLRFATSGITAENDGRPI
EECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCHH
LEQAEAAGLQPEFGCRMGICFACTAVKTSGCTRNLRTGDENDDPDQHIQLCITAPVGDVS
HHHHHHCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEE
INL
EEC
>Mature Secondary Structure 
TFLTKATRRILTPDSSLGRLLTAALTPHAVDRYLELVDPMITWEEARARVIRVQRRTTR
CCHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
SVTLTLRTTHQFKGFHAGQFVQLGVVIDGVRHVRCFSPSCADDAREIIELTIARRPDGLV
EEEEEEEECHHCCCCCCCCEEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHH
SNYLYKHAAVGDVYSITPAAGTFVLPAPRPIRTLLIAAGSGITPVLSMARTLVGNGYPGQ
HHHHHHHHCCCCEEEECCCCCEEEECCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCCCC
LAVLYYAPTAADNAYAGELAALGEVPSVTVRVEYTRDGGQHFSAEQLQAVAPWHADAQTF
EEEEEEECCCCCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCCCCEE
LCGPPSLHEAVSALYAERGLSDRLHTEEFTLATAGNTGEAGGVLRFATSGITAENDGRPI
EECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCHH
LEQAEAAGLQPEFGCRMGICFACTAVKTSGCTRNLRTGDENDDPDQHIQLCITAPVGDVS
HHHHHHCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEE
INL
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dihydropteridine; 2 nitric oxide; O2; NAD(P)H [C]

Specific reaction: NAD(P)H + dihydropteridine = NAD(P)+ @TETR01.txt*tetrahydropteridine! 2 nitric oxide + 2 O2 + NAD(P)H = 2 NO3- + NAD(P) + Proton [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]