Click here to switch to the map view.

The map label for this gene is degU [H]

Identifier: 169628613

GI number: 169628613

Start: 1542949

End: 1543605

Strand: Direct

Name: degU [H]

Synonym: MAB_1522

Alternate gene names: 169628613

Gene position: 1542949-1543605 (Clockwise)

Preceding gene: 169628612

Following gene: 169628617

Centisome position: 30.45

GC content: 64.54

Gene sequence:

>657_bases
ATGACTGACACCGAGGTGGGCGTCCTGCTGGTCGATGATCAGGAGCTTGTACGAACGGGGTTGCGCCGGATTCTGCGTCG
CAAGGACGGCTTCGCGATAGTGGGGGAGTGCGCCGATGGGAGCGAGGTCGCCGCTGCGGTGAGCCGGGCGCGGCCCGACG
TGGTGATCATGGATCTGCGGATGAAGCAGATGAGTGGTATCGAGGCGATTCGCTTGCTGCATGCCGCGCAGGGACCGCCG
GCGCTGGCGCTCACCACATTTGACGACGACGAGCTGCTCTCGGGTGCGCTGCGCGCCGGTGCTGCCGGGTTCATTCTGAA
GGACTCGCCCGCCGAGGAGCTGGTACGCGCAGTGCATGCGGTGGCGCGCGGTGAGGCGTACCTGGACCCTGCGGTGACCT
CGCGTGTGCTCAATGCCTATCGACGGGCACCCGCCGCAGTGTCGGGGGATGCCCAGGACAAACTCACCGCACGGGAACTG
GATGTGCTGGCACTCATCGCCTCCGGGGCAACCAACTCCGAAATCGCTGAACAACTCGTGATATCGGAGGTCACGGTCAA
GAGTCACATCGGGCGCATCTTCGTCAAACTCGATCTACGGGACCGTGCCGCGGCCATCGTCTACGCCTACGACCACGGCA
TCGTGACACCGAAATAG

Upstream 100 bases:

>100_bases
GCGGGGCGGGCGGAAGATGGCTGGACAGTTTCGGCGAGTGTCCCGTTGGAATCCAATGGGACAGACTGCCGTTCCCGGCG
CAGGAAAGTGCTGTGGCGTC

Downstream 100 bases:

>100_bases
ATTTACAGCAGGTTCTTTTCGCGGATGCTCTCTAGAGCCTCGTGTAGCTGTTCGAGCTCGCGGCGCAAGTAGTCACGCGT
CGCGACCTCGCCAACTGCCA

Product: putative two-component system response regulator LuxR

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTDTEVGVLLVDDQELVRTGLRRILRRKDGFAIVGECADGSEVAAAVSRARPDVVIMDLRMKQMSGIEAIRLLHAAQGPP
ALALTTFDDDELLSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVLNAYRRAPAAVSGDAQDKLTAREL
DVLALIASGATNSEIAEQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK

Sequences:

>Translated_218_residues
MTDTEVGVLLVDDQELVRTGLRRILRRKDGFAIVGECADGSEVAAAVSRARPDVVIMDLRMKQMSGIEAIRLLHAAQGPP
ALALTTFDDDELLSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVLNAYRRAPAAVSGDAQDKLTAREL
DVLALIASGATNSEIAEQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK
>Mature_217_residues
TDTEVGVLLVDDQELVRTGLRRILRRKDGFAIVGECADGSEVAAAVSRARPDVVIMDLRMKQMSGIEAIRLLHAAQGPPA
LALTTFDDDELLSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVLNAYRRAPAAVSGDAQDKLTARELD
VLALIASGATNSEIAEQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=210, Percent_Identity=37.6190476190476, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=32.0754716981132, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787473, Length=208, Percent_Identity=34.1346153846154, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=32.1428571428571, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788712, Length=198, Percent_Identity=25.7575757575758, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=25.3658536585366, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082052, Length=102, Percent_Identity=37.2549019607843, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=27.9620853080569, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23280; Mature: 23149

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTEVGVLLVDDQELVRTGLRRILRRKDGFAIVGECADGSEVAAAVSRARPDVVIMDLR
CCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECH
MKQMSGIEAIRLLHAAQGPPALALTTFDDDELLSGALRAGAAGFILKDSPAEELVRAVHA
HHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VARGEAYLDPAVTSRVLNAYRRAPAAVSGDAQDKLTARELDVLALIASGATNSEIAEQLV
HHCCCHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHH
ISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK
HHHHHHHHHCCEEEEEEECCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
TDTEVGVLLVDDQELVRTGLRRILRRKDGFAIVGECADGSEVAAAVSRARPDVVIMDLR
CCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECH
MKQMSGIEAIRLLHAAQGPPALALTTFDDDELLSGALRAGAAGFILKDSPAEELVRAVHA
HHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VARGEAYLDPAVTSRVLNAYRRAPAAVSGDAQDKLTARELDVLALIASGATNSEIAEQLV
HHCCCHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHH
ISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK
HHHHHHHHHCCEEEEEEECCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]