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The map label for this gene is argS

Identifier: 169628524

GI number: 169628524

Start: 1436823

End: 1438475

Strand: Direct

Name: argS

Synonym: MAB_1433

Alternate gene names: 169628524

Gene position: 1436823-1438475 (Clockwise)

Preceding gene: 169628523

Following gene: 169628525

Centisome position: 28.36

GC content: 65.46

Gene sequence:

>1653_bases
GTGACTCCCGCCGACCTCGCCGACCTGCTGCGTTCCACCGCTACCACGGTGCTGGACGAGCGAGGTCTGGACACGTCGGC
ACTGCCCGCCGTGGTGACAGTCGAACGGCCCCGTAATCCGGAGCACGGAGACTACGCCACCAACGTGGCCTTACAGGTCG
CCAAAAAGGTGGGCGTCGCGCCGCGTGACCTGGCCGGCTGGCTCGTCGAGGCCCTCGTGTCCCACGCGGCGATCGCCGGG
GCCGAGATCGCCGGGCCCGGGTTCGTGAACCTGCGGATCGCGGCCGACGCACAGGGCACCATCGTGGCGAACATCCTGAA
GGCGGGGGAGACCTACGGGAATTCCGACGCGCAAGGCACGCACACCATCAACCTGGAGTTCGTCTCCGCCAACCCGACGG
GCCCGATTCACATCGGCGGTACCCGATGGGCCGCGGTGGGCGATGCGCTCGGCCGCCTGTTGGCTCGTCAGGGCGCCAAG
GTCACCCGCGAGTACTACTTCAACGACCACGGCGCCCAGATCGACCGGTTTGTCCGGTCGCTCATCGCGTCGGCCGAGGG
GAAGGAAGCCCCGGAAGACGGGTACGCCGGCGACTACATCGCCGATATCGCCAAGCAGGTCATCACCCAGCGGCCCGAGG
CGCTCACGCTGACGGAGCCCGAGAGATCCGAGGTCTTCCGAGAGATTGGCGTGGACTTGATGTTCACCCACATCAAGGAG
TCACTGCACGAGTTCGGCACGGATTTCGATGTCTTCACCCACGAGGACTCGATGCACACGTCAGGCCGGGTGCAGGAGGC
CATCGCCCAGCTGCGCAAGACCGGAAACATCTACGAGAAGGACGGCGCGTCCTGGCTGCGGTCGAGCAACTTCGGTGACG
ACAAGGATCGTGTCGTCATCAAGAGCGACGGCAACCCCGCCTACATCGCCGGTGATATCGCCTATTACCTCGACAAGCGC
GAGCGGGGCTTCGACCTGTGCATCTACATGCTCGGTGCCGATCATCACGGGTATATCGCGCGCCTGAAAGCCGTTGCCGC
CGCACTGGGTTACGACGCCGACAGCGTTGAGGTGCTTATCGGTCAGATGGTCAACCTGGTGCGTGATGGCCAGCCGGTGC
GCATGTCCAAGCGCGCGGGGACCGTCATCACCCTCGACGACTTGGTAGACGCCATCGGCGTGGATGCGGCTCGCTATGCG
CTGATCCGTTCCTCGGTGGACACCTCGATCGACATTGATCTGGAGCTGTGGGCGTCCGCGTCGAGTGAGAACCCGGTCTA
CTACGTCCAATACGCGCACGCACGGCTCTGTGCACTGGCCCGCAACGCGGCCGATCTGGGTCTGCAGCACTCGACGGAGC
ACCTGGAGCTGCTCACCCACGAGAAAGAAGGTGCGCTCATCCGTGGGCTCGGCGAGTTCGGCCGGATCCTGCAGAACGCC
GCAGCGTTGCGCGAACCACACCGTGTCGCAAGGTATTTGGAAGACATCGCCGGCGACTACCACCGGTTCTATGATTCGTG
CCGGGTGCTCCCGCAAGGCGACGAGACCCCCGGCGACCTCCACGCGGCCCGGCTCGCACTGTGCCTGGCCACTCGCCAAG
TCATCGCCAACGGCCTGGACATCCTCGGCGTGAGCGCACCGGAGCGGATGTGA

Upstream 100 bases:

>100_bases
GCGGAGACAGCCTAGCGCATCCACACGTGGACCCCGACCACCGTTTCGGTCGGGGTAAAGGATTCGGGGCCTGGATACCC
CAGCCCATAGGATGATCGCC

Downstream 100 bases:

>100_bases
GCGCACACCCGGCAGGCCCCCGCCACGCAGAAGGGGAACAGCACACCGCCATGAGCAGTGCACCACCGGCTAATCCGACC
GAATTGGCGTCAAATGTATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTPADLADLLRSTATTVLDERGLDTSALPAVVTVERPRNPEHGDYATNVALQVAKKVGVAPRDLAGWLVEALVSHAAIAG
AEIAGPGFVNLRIAADAQGTIVANILKAGETYGNSDAQGTHTINLEFVSANPTGPIHIGGTRWAAVGDALGRLLARQGAK
VTREYYFNDHGAQIDRFVRSLIASAEGKEAPEDGYAGDYIADIAKQVITQRPEALTLTEPERSEVFREIGVDLMFTHIKE
SLHEFGTDFDVFTHEDSMHTSGRVQEAIAQLRKTGNIYEKDGASWLRSSNFGDDKDRVVIKSDGNPAYIAGDIAYYLDKR
ERGFDLCIYMLGADHHGYIARLKAVAAALGYDADSVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVDAIGVDAARYA
LIRSSVDTSIDIDLELWASASSENPVYYVQYAHARLCALARNAADLGLQHSTEHLELLTHEKEGALIRGLGEFGRILQNA
AALREPHRVARYLEDIAGDYHRFYDSCRVLPQGDETPGDLHAARLALCLATRQVIANGLDILGVSAPERM

Sequences:

>Translated_550_residues
MTPADLADLLRSTATTVLDERGLDTSALPAVVTVERPRNPEHGDYATNVALQVAKKVGVAPRDLAGWLVEALVSHAAIAG
AEIAGPGFVNLRIAADAQGTIVANILKAGETYGNSDAQGTHTINLEFVSANPTGPIHIGGTRWAAVGDALGRLLARQGAK
VTREYYFNDHGAQIDRFVRSLIASAEGKEAPEDGYAGDYIADIAKQVITQRPEALTLTEPERSEVFREIGVDLMFTHIKE
SLHEFGTDFDVFTHEDSMHTSGRVQEAIAQLRKTGNIYEKDGASWLRSSNFGDDKDRVVIKSDGNPAYIAGDIAYYLDKR
ERGFDLCIYMLGADHHGYIARLKAVAAALGYDADSVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVDAIGVDAARYA
LIRSSVDTSIDIDLELWASASSENPVYYVQYAHARLCALARNAADLGLQHSTEHLELLTHEKEGALIRGLGEFGRILQNA
AALREPHRVARYLEDIAGDYHRFYDSCRVLPQGDETPGDLHAARLALCLATRQVIANGLDILGVSAPERM
>Mature_549_residues
TPADLADLLRSTATTVLDERGLDTSALPAVVTVERPRNPEHGDYATNVALQVAKKVGVAPRDLAGWLVEALVSHAAIAGA
EIAGPGFVNLRIAADAQGTIVANILKAGETYGNSDAQGTHTINLEFVSANPTGPIHIGGTRWAAVGDALGRLLARQGAKV
TREYYFNDHGAQIDRFVRSLIASAEGKEAPEDGYAGDYIADIAKQVITQRPEALTLTEPERSEVFREIGVDLMFTHIKES
LHEFGTDFDVFTHEDSMHTSGRVQEAIAQLRKTGNIYEKDGASWLRSSNFGDDKDRVVIKSDGNPAYIAGDIAYYLDKRE
RGFDLCIYMLGADHHGYIARLKAVAAALGYDADSVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVDAIGVDAARYAL
IRSSVDTSIDIDLELWASASSENPVYYVQYAHARLCALARNAADLGLQHSTEHLELLTHEKEGALIRGLGEFGRILQNAA
ALREPHRVARYLEDIAGDYHRFYDSCRVLPQGDETPGDLHAARLALCLATRQVIANGLDILGVSAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1788184, Length=562, Percent_Identity=26.3345195729537, Blast_Score=131, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6320548, Length=611, Percent_Identity=24.8772504091653, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321883, Length=609, Percent_Identity=23.9737274220033, Blast_Score=111, Evalue=3e-25,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_MYCA9 (B1MLU2)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702173.1
- ProteinModelPortal:   B1MLU2
- EnsemblBacteria:   EBMYCT00000007145
- GeneID:   5967478
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1433
- GeneTree:   EBGT00050000016532
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   MABS561007:MAB_1433-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 59680; Mature: 59549

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPADLADLLRSTATTVLDERGLDTSALPAVVTVERPRNPEHGDYATNVALQVAKKVGVA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PRDLAGWLVEALVSHAAIAGAEIAGPGFVNLRIAADAQGTIVANILKAGETYGNSDAQGT
CHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCE
HTINLEFVSANPTGPIHIGGTRWAAVGDALGRLLARQGAKVTREYYFNDHGAQIDRFVRS
EEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHH
LIASAEGKEAPEDGYAGDYIADIAKQVITQRPEALTLTEPERSEVFREIGVDLMFTHIKE
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCHHHHHHHHHH
SLHEFGTDFDVFTHEDSMHTSGRVQEAIAQLRKTGNIYEKDGASWLRSSNFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCEEEE
KSDGNPAYIAGDIAYYLDKRERGFDLCIYMLGADHHGYIARLKAVAAALGYDADSVEVLI
ECCCCCEEEECHHHEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHH
GQMVNLVRDGQPVRMSKRAGTVITLDDLVDAIGVDAARYALIRSSVDTSIDIDLELWASA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEECC
SSENPVYYVQYAHARLCALARNAADLGLQHSTEHLELLTHEKEGALIRGLGEFGRILQNA
CCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AALREPHRVARYLEDIAGDYHRFYDSCRVLPQGDETPGDLHAARLALCLATRQVIANGLD
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
ILGVSAPERM
EEECCCCCCC
>Mature Secondary Structure 
TPADLADLLRSTATTVLDERGLDTSALPAVVTVERPRNPEHGDYATNVALQVAKKVGVA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PRDLAGWLVEALVSHAAIAGAEIAGPGFVNLRIAADAQGTIVANILKAGETYGNSDAQGT
CHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCE
HTINLEFVSANPTGPIHIGGTRWAAVGDALGRLLARQGAKVTREYYFNDHGAQIDRFVRS
EEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHH
LIASAEGKEAPEDGYAGDYIADIAKQVITQRPEALTLTEPERSEVFREIGVDLMFTHIKE
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCHHHHHHHHHH
SLHEFGTDFDVFTHEDSMHTSGRVQEAIAQLRKTGNIYEKDGASWLRSSNFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCEEEE
KSDGNPAYIAGDIAYYLDKRERGFDLCIYMLGADHHGYIARLKAVAAALGYDADSVEVLI
ECCCCCEEEECHHHEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHH
GQMVNLVRDGQPVRMSKRAGTVITLDDLVDAIGVDAARYALIRSSVDTSIDIDLELWASA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEECC
SSENPVYYVQYAHARLCALARNAADLGLQHSTEHLELLTHEKEGALIRGLGEFGRILQNA
CCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AALREPHRVARYLEDIAGDYHRFYDSCRVLPQGDETPGDLHAARLALCLATRQVIANGLD
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
ILGVSAPERM
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA