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The map label for this gene is sigW [H]

Identifier: 169628453

GI number: 169628453

Start: 1359744

End: 1360514

Strand: Direct

Name: sigW [H]

Synonym: MAB_1362

Alternate gene names: 169628453

Gene position: 1359744-1360514 (Clockwise)

Preceding gene: 169628447

Following gene: 169628454

Centisome position: 26.83

GC content: 64.33

Gene sequence:

>771_bases
ATGTCGCGATCCATCCTGAACCAGAGCCCGAGCGACCCGCGTCTATCCGGGAATAACACCGATGGCATCTGGGTTGAGCA
GGCTGACGGTCTCCCCACTGGGGGCGAGGCAGCCGTAACCGAACAGGAGGAACACGCGATTTCGCTTACGCGTATCAGCG
AGCCCGATTACACCGAATTCGTCGACGCCGCCAACGCCGACGAACTATCCGGGACCGCAGTATTCGATGCCACTGGAGAC
CAGGCCGCCATGCCGTCCTGGGATGAACTGGTTCGTGAGCATGCCGACCGCGTGTACCGCCTGGCGTACCGGCTTTCCGG
CAGCCAGCAAGATGCCGAGGACCTGACACAGGAAACCTTCATCAGGGTGTTCCGCTCGTTGCAGAACTACCAGCCCGGCA
CCTTCGAGGGTTGGCTGCACCGCATCACCACCAACCTGTTCCTCGACATGGTTCGTCGCCGCGGGCGCATCCGCATGGAA
GCGCTGCCCGAGGACTACGACCGGGTGCCGGCTACCGACCCCGATCCCGAGCAGATCTATCACGACGCCCAGCTGGGTGC
GGACCTGCAGGCCGCACTGGATTCATTGGCACCGGAGTTCCGTGCCGCCGTGGTCCTGTGCGATATCGAAGGTCTGTCCT
ACGAGGAGATCGGCGCCACCCTGGATGTGAAGCTCGGCACCGTCCGCAGCCGTATCCACCGCGGTCGGCAGGCCATCCGG
GAGTACCTGGCTGCACACTCCTCGGCATCCGCGCTCGCGGCCGCCGAGTAG

Upstream 100 bases:

>100_bases
TGGATGGAACTGCCTGGTGAGATCGGATCGAGACCGCATTCTCAGGAAGAGTTAAGTTAGCTCCTAAGTGACCCACACCT
GGGTGGTAGAGGGTCAGTGC

Downstream 100 bases:

>100_bases
CGCGCGACACCATTGGTGCAGGTTGGTACGCAATGAGTACATTCGCGCGCTATCTTCGAGGTAGGCCGGTACGAGTCCGC
CGGCCATTCCGAACCGAAGG

Product: alternative RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSRSILNQSPSDPRLSGNNTDGIWVEQADGLPTGGEAAVTEQEEHAISLTRISEPDYTEFVDAANADELSGTAVFDATGD
QAAMPSWDELVREHADRVYRLAYRLSGSQQDAEDLTQETFIRVFRSLQNYQPGTFEGWLHRITTNLFLDMVRRRGRIRME
ALPEDYDRVPATDPDPEQIYHDAQLGADLQAALDSLAPEFRAAVVLCDIEGLSYEEIGATLDVKLGTVRSRIHRGRQAIR
EYLAAHSSASALAAAE

Sequences:

>Translated_256_residues
MSRSILNQSPSDPRLSGNNTDGIWVEQADGLPTGGEAAVTEQEEHAISLTRISEPDYTEFVDAANADELSGTAVFDATGD
QAAMPSWDELVREHADRVYRLAYRLSGSQQDAEDLTQETFIRVFRSLQNYQPGTFEGWLHRITTNLFLDMVRRRGRIRME
ALPEDYDRVPATDPDPEQIYHDAQLGADLQAALDSLAPEFRAAVVLCDIEGLSYEEIGATLDVKLGTVRSRIHRGRQAIR
EYLAAHSSASALAAAE
>Mature_255_residues
SRSILNQSPSDPRLSGNNTDGIWVEQADGLPTGGEAAVTEQEEHAISLTRISEPDYTEFVDAANADELSGTAVFDATGDQ
AAMPSWDELVREHADRVYRLAYRLSGSQQDAEDLTQETFIRVFRSLQNYQPGTFEGWLHRITTNLFLDMVRRRGRIRMEA
LPEDYDRVPATDPDPEQIYHDAQLGADLQAALDSLAPEFRAAVVLCDIEGLSYEEIGATLDVKLGTVRSRIHRGRQAIRE
YLAAHSSASALAAAE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=172, Percent_Identity=33.1395348837209, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 28352; Mature: 28221

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSILNQSPSDPRLSGNNTDGIWVEQADGLPTGGEAAVTEQEEHAISLTRISEPDYTEF
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHH
VDAANADELSGTAVFDATGDQAAMPSWDELVREHADRVYRLAYRLSGSQQDAEDLTQETF
HHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
IRVFRSLQNYQPGTFEGWLHRITTNLFLDMVRRRGRIRMEALPEDYDRVPATDPDPEQIY
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHCCCCCCCCHHHHH
HDAQLGADLQAALDSLAPEFRAAVVLCDIEGLSYEEIGATLDVKLGTVRSRIHRGRQAIR
HHHHHCCHHHHHHHHHCHHHHHEEEEEECCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHH
EYLAAHSSASALAAAE
HHHHHCCCCCHHHCCC
>Mature Secondary Structure 
SRSILNQSPSDPRLSGNNTDGIWVEQADGLPTGGEAAVTEQEEHAISLTRISEPDYTEF
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHH
VDAANADELSGTAVFDATGDQAAMPSWDELVREHADRVYRLAYRLSGSQQDAEDLTQETF
HHCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
IRVFRSLQNYQPGTFEGWLHRITTNLFLDMVRRRGRIRMEALPEDYDRVPATDPDPEQIY
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHCCCCCCCCHHHHH
HDAQLGADLQAALDSLAPEFRAAVVLCDIEGLSYEEIGATLDVKLGTVRSRIHRGRQAIR
HHHHHCCHHHHHHHHHCHHHHHEEEEEECCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHH
EYLAAHSSASALAAAE
HHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]