| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is fabG [H]
Identifier: 169628303
GI number: 169628303
Start: 1223145
End: 1223999
Strand: Reverse
Name: fabG [H]
Synonym: MAB_1210c
Alternate gene names: 169628303
Gene position: 1223999-1223145 (Counterclockwise)
Preceding gene: 169628304
Following gene: 169628301
Centisome position: 24.16
GC content: 66.55
Gene sequence:
>855_bases ATGCCCAATTGTGTTGTCGTTGGGGGTAGCCGGGGCATCGGCCGTGCGGTGGCGCTGCTACTCGGCGAGCTGGGCACCAA TGTGGTGGTGAACGGCCGTCATGCCGACGTGGTCGACGACACCGTCGGTGCGATCACGTCGAGCGGTGGCACGGCGGTCG GCTTTGTCGGCGCGCCGGATAACGAGCGGACGGCCACGGATCTGATCGACACCTGCCGCACCCAGTACGGTGGCATCGAT GCGTTGATCAACTGCGCGGGCATACCCGAACCCACCGGCTCGTCCATCCTCACCATCACCTCCGGCGACTTCCACCGGCT CATCGACGCACATCTGGGCACCGTGTTCCACACCTGCCGTGTGGTCGCGCCGCTCATGGTTCAGCAGCGACACGGGGCCA TCATCAACACCGGATCGACTGCTTCCCTAGGGATCTACGGCGGCACGGGATATCCCGCGGGCAAGGCGGCCGTCAACGGA CTCACGCTGGCGATCGCCGCCGAGCTGAAACGCAGCGGCGTGCGCGCCAACGTGATCTGCCCGGGTGCCCGCACCCGGTT GTCCGAGGGACCGGAGTACACCGCGCACCTGCACGATCTGCACACCCGGGGATTGCTCGACGACATGACCCTGCAGGCGT CGTTGGTGCCGGCACCGCCAGCGTGCGTGGCACCGCTGTACGCCTACCTGGCAGGCGATCTGTCTGCCCGCGTCACCGGA CAGATCTTTCTTGCCGCGGGCGGTTTCATCGGACGTTTCAAGCGCCAGACGCCGGTACCGCTGGGATACCGCGATCACGC GCTGGACGCACCGTGGTCGATGGAGGAGATCGACGACCTGATGGGCAGACGCTGA
Upstream 100 bases:
>100_bases TGCCGGACATCTCGCGGATCGGGGATGCGCCCCGGTTCCATTCCGGCTGGATCAACGGGATCAAGAAGTTCGACACGGCG TACTGCCCCGTCACGCACTG
Downstream 100 bases:
>100_bases CTACTGCCCAAACCGCCGGTTTCGCGCGGCGTAATCGCGCAGCGCGCGCAGGAAGTCCACCCGCCGGAACTCGGGCCAAT AGGCGTCGGTGAACCACATC
Product: putative short chain dehydrogenase/reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 284; Mature: 283
Protein sequence:
>284_residues MPNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQYGGID ALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNG LTLAIAAELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR
Sequences:
>Translated_284_residues MPNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQYGGID ALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNG LTLAIAAELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR >Mature_283_residues PNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPDNERTATDLIDTCRTQYGGIDA LINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCRVVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNGL TLAIAAELKRSGVRANVICPGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTGQ IFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI4504505, Length=290, Percent_Identity=28.9655172413793, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI40254992, Length=180, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI66933014, Length=188, Percent_Identity=29.7872340425532, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI209862901, Length=190, Percent_Identity=32.6315789473684, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI19923983, Length=190, Percent_Identity=32.6315789473684, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI19923817, Length=187, Percent_Identity=26.7379679144385, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=27.6264591439689, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=27.0916334661355, Blast_Score=78, Evalue=8e-16, Organism=Escherichia coli, GI87082160, Length=192, Percent_Identity=29.6875, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI2367175, Length=188, Percent_Identity=31.9148936170213, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=25.7692307692308, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1786812, Length=241, Percent_Identity=28.2157676348548, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=27.710843373494, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=27.027027027027, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17568967, Length=258, Percent_Identity=29.4573643410853, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=28.3524904214559, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=27.2373540856031, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=26.7924528301887, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71994604, Length=264, Percent_Identity=28.030303030303, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=29.9610894941634, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=25, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=27.1317829457364, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994600, Length=266, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=28.8973384030418, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.5813953488372, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=29.8804780876494, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=26.8939393939394, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17538182, Length=194, Percent_Identity=29.3814432989691, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=26.3358778625954, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=26.7716535433071, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17564282, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=25.7692307692308, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17563726, Length=186, Percent_Identity=29.5698924731183, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71997099, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=26.9961977186312, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=25.968992248062, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17555612, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=25.2918287937743, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=292, Percent_Identity=30.4794520547945, Blast_Score=103, Evalue=2e-23, Organism=Drosophila melanogaster, GI18859837, Length=293, Percent_Identity=30.3754266211604, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=30.241935483871, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=29.0322580645161, Blast_Score=81, Evalue=1e-15, Organism=Drosophila melanogaster, GI17737361, Length=195, Percent_Identity=31.2820512820513, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=27.4193548387097, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=23.8461538461538, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 29505; Mature: 29374
Theoretical pI: Translated: 6.78; Mature: 6.78
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPD CCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHEECCCCCEEEEEECCC NERTATDLIDTCRTQYGGIDALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCR CCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH VVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNGLTLAIAAELKRSGVRANVIC HHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCHHHHCCEEEEEEHHHHHCCCEEEEEC PGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG CCHHHHCCCCCCHHHHHHHHHHCCCHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEE QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR EEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC >Mature Secondary Structure PNCVVVGGSRGIGRAVALLLGELGTNVVVNGRHADVVDDTVGAITSSGGTAVGFVGAPD CCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHEECCCCCEEEEEECCC NERTATDLIDTCRTQYGGIDALINCAGIPEPTGSSILTITSGDFHRLIDAHLGTVFHTCR CCCHHHHHHHHHHHHHCCHHHHEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH VVAPLMVQQRHGAIINTGSTASLGIYGGTGYPAGKAAVNGLTLAIAAELKRSGVRANVIC HHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCHHHHCCEEEEEEHHHHHCCCEEEEEC PGARTRLSEGPEYTAHLHDLHTRGLLDDMTLQASLVPAPPACVAPLYAYLAGDLSARVTG CCHHHHCCCCCCHHHHHHHHHHCCCHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEE QIFLAAGGFIGRFKRQTPVPLGYRDHALDAPWSMEEIDDLMGRR EEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]