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The map label for this gene is yabD [H]

Identifier: 169628222

GI number: 169628222

Start: 1140651

End: 1141550

Strand: Direct

Name: yabD [H]

Synonym: MAB_1129

Alternate gene names: 169628222

Gene position: 1140651-1141550 (Clockwise)

Preceding gene: 169628216

Following gene: 169628223

Centisome position: 22.51

GC content: 65.0

Gene sequence:

>900_bases
ATGACGCCCGGCAATAACAGGCAGGCCCCACCCGACCGCATTCGTTCCCGCCCACCCGACCCTGAGCCGCTCGCGCCTCT
CATTGACGCCCACACCCATTTGGACGCGTGCGGCGCCGTCACGGCAGCGGATGTGCGCGCCATGGTCGACCATGCGGAGT
CCGTCGGTGTCGGACGAGTCGTCACGGTCGCCGACGACCTGGACTCGGCCCGGTGGGCGGTCTCGGCGGCGGCCGCCGAT
CCACGTGTCTATGCCGCGGTGGCGTTGCATCCCACTCGCGCGGGGAACCTCACCGACGAGGCCCGTGCCGAATTGGAGAC
GTTGGCGGCTCATCCCCGGGTGGTGGCGATCGGGGAGACCGGTCTGGACCTGTATTGGCCGGGTCGTTTGGAGGGGTGCG
CGGAGCCGTCGATTCAGCGCGAGGCATTTGCTTGGCATATCGAGCTGGCTAAGCGGACGGGCAAGCCGCTGATGATTCAC
AACCGTGATGCGGACGCGGACGTCCTCGATGTGCTCAAGGCGGAGGGCGCGCCAGGCTCGGTTATCTTCCACTGCTTCTC
GTCGGATGCTGACATGGCGAAAAAATGCATCGCTGAGGGCTGGATTCTGAGCCTGTCAGGGACGGTCAGCTTCAAGAACG
CCCGCGCTCTGCAAGAGGCTGCCGCTCTCATTCCCGACGAACAACTGCTGGTAGAGACCGATGCGCCCTATCTGACACCC
CACCCGCACCGGGGTGCGCCCAACGAGCCGTACTGCCTGCCGTACACCGTTCGCGCCCTGGCGGAAATAACTGGGCGAAC
CGCTGACCGGTTAGCGGAAGCCTCGTCTACTACCGCAATCGCGGTGTTCAAGATCGTTGATGAGTTGCCCCCACGCGATG
CTTTCGTTACCGTGTCGTGA

Upstream 100 bases:

>100_bases
TCGCCGTTCGGATACGCGATGGCGGTGGTGATGTAGAACGGATCCAATGATTCAGGCATGGTGGGAGCAACTGTATCTAT
CCAAATAGAATGGATACCTG

Downstream 100 bases:

>100_bases
TCAATGAGGATGATTATCAGCCGAATTTCGCCGTGTGAAATCCGGTATCGAGGCTCCGAAACGAACGCAGGAAACCCCTA
CTCGTGAATGCACTGACGAA

Product: deoxyribonuclease TatD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTPGNNRQAPPDRIRSRPPDPEPLAPLIDAHTHLDACGAVTAADVRAMVDHAESVGVGRVVTVADDLDSARWAVSAAAAD
PRVYAAVALHPTRAGNLTDEARAELETLAAHPRVVAIGETGLDLYWPGRLEGCAEPSIQREAFAWHIELAKRTGKPLMIH
NRDADADVLDVLKAEGAPGSVIFHCFSSDADMAKKCIAEGWILSLSGTVSFKNARALQEAAALIPDEQLLVETDAPYLTP
HPHRGAPNEPYCLPYTVRALAEITGRTADRLAEASSTTAIAVFKIVDELPPRDAFVTVS

Sequences:

>Translated_299_residues
MTPGNNRQAPPDRIRSRPPDPEPLAPLIDAHTHLDACGAVTAADVRAMVDHAESVGVGRVVTVADDLDSARWAVSAAAAD
PRVYAAVALHPTRAGNLTDEARAELETLAAHPRVVAIGETGLDLYWPGRLEGCAEPSIQREAFAWHIELAKRTGKPLMIH
NRDADADVLDVLKAEGAPGSVIFHCFSSDADMAKKCIAEGWILSLSGTVSFKNARALQEAAALIPDEQLLVETDAPYLTP
HPHRGAPNEPYCLPYTVRALAEITGRTADRLAEASSTTAIAVFKIVDELPPRDAFVTVS
>Mature_298_residues
TPGNNRQAPPDRIRSRPPDPEPLAPLIDAHTHLDACGAVTAADVRAMVDHAESVGVGRVVTVADDLDSARWAVSAAAADP
RVYAAVALHPTRAGNLTDEARAELETLAAHPRVVAIGETGLDLYWPGRLEGCAEPSIQREAFAWHIELAKRTGKPLMIHN
RDADADVLDVLKAEGAPGSVIFHCFSSDADMAKKCIAEGWILSLSGTVSFKNARALQEAAALIPDEQLLVETDAPYLTPH
PHRGAPNEPYCLPYTVRALAEITGRTADRLAEASSTTAIAVFKIVDELPPRDAFVTVS

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=202, Percent_Identity=31.1881188118812, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI225903424, Length=191, Percent_Identity=31.9371727748691, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI110349730, Length=172, Percent_Identity=27.3255813953488, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI225903439, Length=185, Percent_Identity=31.8918918918919, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI110349734, Length=172, Percent_Identity=27.3255813953488, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI226061853, Length=178, Percent_Identity=26.9662921348315, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI226061614, Length=166, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787342, Length=263, Percent_Identity=34.2205323193916, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI87082439, Length=263, Percent_Identity=27.3764258555133, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994985, Length=251, Percent_Identity=29.8804780876494, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559024, Length=271, Percent_Identity=26.5682656826568, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=26.3157894736842, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=309, Percent_Identity=23.9482200647249, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648690, Length=311, Percent_Identity=27.9742765273312, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221330018, Length=211, Percent_Identity=28.436018957346, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586117, Length=211, Percent_Identity=28.436018957346, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 31949; Mature: 31818

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPGNNRQAPPDRIRSRPPDPEPLAPLIDAHTHLDACGAVTAADVRAMVDHAESVGVGRV
CCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
VTVADDLDSARWAVSAAAADPRVYAAVALHPTRAGNLTDEARAELETLAAHPRVVAIGET
EEEECCCCCHHHEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCC
GLDLYWPGRLEGCAEPSIQREAFAWHIELAKRTGKPLMIHNRDADADVLDVLKAEGAPGS
CCEEEECCCCCCCCCCCCCHHHHHEEEEEHHHCCCEEEEECCCCCHHHHHHHHCCCCCCE
VIFHCFSSDADMAKKCIAEGWILSLSGTVSFKNARALQEAAALIPDEQLLVETDAPYLTP
EEEEEECCCHHHHHHHHHCCEEEEEECEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCC
HPHRGAPNEPYCLPYTVRALAEITGRTADRLAEASSTTAIAVFKIVDELPPRDAFVTVS
CCCCCCCCCCEECHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
TPGNNRQAPPDRIRSRPPDPEPLAPLIDAHTHLDACGAVTAADVRAMVDHAESVGVGRV
CCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
VTVADDLDSARWAVSAAAADPRVYAAVALHPTRAGNLTDEARAELETLAAHPRVVAIGET
EEEECCCCCHHHEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCC
GLDLYWPGRLEGCAEPSIQREAFAWHIELAKRTGKPLMIHNRDADADVLDVLKAEGAPGS
CCEEEECCCCCCCCCCCCCHHHHHEEEEEHHHCCCEEEEECCCCCHHHHHHHHCCCCCCE
VIFHCFSSDADMAKKCIAEGWILSLSGTVSFKNARALQEAAALIPDEQLLVETDAPYLTP
EEEEEECCCHHHHHHHHHCCEEEEEECEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCC
HPHRGAPNEPYCLPYTVRALAEITGRTADRLAEASSTTAIAVFKIVDELPPRDAFVTVS
CCCCCCCCCCEECHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]