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The map label for this gene is fadE12 [H]

Identifier: 169628165

GI number: 169628165

Start: 1081412

End: 1082581

Strand: Reverse

Name: fadE12 [H]

Synonym: MAB_1070c

Alternate gene names: 169628165

Gene position: 1082581-1081412 (Counterclockwise)

Preceding gene: 169628166

Following gene: 169628164

Centisome position: 21.36

GC content: 64.19

Gene sequence:

>1170_bases
ATGACCCAGCCGAACCCGTACGTCGAGTCCGACGAGCGCAAGGCCCTGCGTCAGGCAGTGGCGTCTCTGGCCGCCAGCTA
CGGCCACGAGTACTACCTGGAGAAGTCCAAGACTCACGAGCCCTTGGCCGAATTGTGGGATGAAGCAGGGAAACTCGGCT
TCCTCGGGGTGAACATTCCGGAGGAGTATGGTGGCGGCGGCGCCGGCATGTACGAGCTCGGGCTCGTCTTCGAAGAGCTC
TCCGCGGCCGGTTGCCCACTGCTGTTGATGGTCGTCTCCCCCGCGATCAATGCCACCATCATCGCCCGGTACGGCACCGA
CGCCCAGAAGAAGAGCTGGCTACCGGCGATGGCCGAGGGCAGCTTCAAGATGGCGTTCGCGATCACCGAGCCCGATGCCG
GCTCCAACTCGCACAACATCATCACCACCGCCAAGCGCGACGGCGGTGACTGGATCCTCAACGGACGCAAGGTCTTCATC
TCTGGTGTCAATGAGGCCAACGCGGTGCTGGTGGTGGCCCGCACCGAAGAAGCCAAGACCGGAAAACTCAAGCCTGCGCT
GTTCGTGGTGCCCACCAACACCAAGGGATTCGAGTACACCCCCATCGATATGCAGCTGACGCTGCCCGAGCAGCAGTTCC
AGGTATTCCTCGACGATGTGCGCGTGCCCGGTGACGCGCTCGTCGGTTCCGAGGACGCCGCACTCATGCAGCTGTTCGCC
GGTCTCAACCCGGAACGAATCATGGGCGCTGCCAGCGGTGTTGGCCTGACTCGGCTCGCACTGAACAAGGCCACCGAGTA
TGTGAAGACCCGCCAGGTGTGGAAGACCCCGATCGGTGCACACCAGGCCATCGCGCACCCGCTGGCCGAGATCAAGGTCG
AACTGGAGCTGGCCAAGCTCATGATGCAGAAGGCGGCCACACTGTACGACTGCGGCGATGACTGGGGCGCCGCGGAGGCC
GCCAACATGGCCAAGTACGCGGCCGCTGATGTGGCCTGCCGCGCGGCGGACCGCGCCGTGCAATCACTGGGTGGCAACGG
GTTGACCACCGAGTACGGCGTGGCACCGCTGTTGAACCTGTCCCGTTTCGGGCGTATCGCCCCGGTCAGCCGCGAGATGA
TTCTCAACTTCGTCGCGCAGACCTCCCTTGGCCTGCCCCGTTCGTACTGA

Upstream 100 bases:

>100_bases
GTGTCGTCGAAATCCTGAATGTCGAACCCGGCCAACAGGTCGAGCTCGGCACCGTACTTGCCCAGTTGGCCGCCGAGGCC
ACCACAGAAGGAGAGCCAGC

Downstream 100 bases:

>100_bases
TTCGTACTCAAGGAGACGCCCCGATGAGTGACACCCTGGTCCAGTACGAGGTCGAAGGCCGTGCCGCACGCCTGACGCTC
GACTCGCCGCACAACCGTAA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTQPNPYVESDERKALRQAVASLAASYGHEYYLEKSKTHEPLAELWDEAGKLGFLGVNIPEEYGGGGAGMYELGLVFEEL
SAAGCPLLLMVVSPAINATIIARYGTDAQKKSWLPAMAEGSFKMAFAITEPDAGSNSHNIITTAKRDGGDWILNGRKVFI
SGVNEANAVLVVARTEEAKTGKLKPALFVVPTNTKGFEYTPIDMQLTLPEQQFQVFLDDVRVPGDALVGSEDAALMQLFA
GLNPERIMGAASGVGLTRLALNKATEYVKTRQVWKTPIGAHQAIAHPLAEIKVELELAKLMMQKAATLYDCGDDWGAAEA
ANMAKYAAADVACRAADRAVQSLGGNGLTTEYGVAPLLNLSRFGRIAPVSREMILNFVAQTSLGLPRSY

Sequences:

>Translated_389_residues
MTQPNPYVESDERKALRQAVASLAASYGHEYYLEKSKTHEPLAELWDEAGKLGFLGVNIPEEYGGGGAGMYELGLVFEEL
SAAGCPLLLMVVSPAINATIIARYGTDAQKKSWLPAMAEGSFKMAFAITEPDAGSNSHNIITTAKRDGGDWILNGRKVFI
SGVNEANAVLVVARTEEAKTGKLKPALFVVPTNTKGFEYTPIDMQLTLPEQQFQVFLDDVRVPGDALVGSEDAALMQLFA
GLNPERIMGAASGVGLTRLALNKATEYVKTRQVWKTPIGAHQAIAHPLAEIKVELELAKLMMQKAATLYDCGDDWGAAEA
ANMAKYAAADVACRAADRAVQSLGGNGLTTEYGVAPLLNLSRFGRIAPVSREMILNFVAQTSLGLPRSY
>Mature_388_residues
TQPNPYVESDERKALRQAVASLAASYGHEYYLEKSKTHEPLAELWDEAGKLGFLGVNIPEEYGGGGAGMYELGLVFEELS
AAGCPLLLMVVSPAINATIIARYGTDAQKKSWLPAMAEGSFKMAFAITEPDAGSNSHNIITTAKRDGGDWILNGRKVFIS
GVNEANAVLVVARTEEAKTGKLKPALFVVPTNTKGFEYTPIDMQLTLPEQQFQVFLDDVRVPGDALVGSEDAALMQLFAG
LNPERIMGAASGVGLTRLALNKATEYVKTRQVWKTPIGAHQAIAHPLAEIKVELELAKLMMQKAATLYDCGDDWGAAEAA
NMAKYAAADVACRAADRAVQSLGGNGLTTEYGVAPLLNLSRFGRIAPVSREMILNFVAQTSLGLPRSY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=31.6353887399464, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI187960098, Length=370, Percent_Identity=31.0810810810811, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557231, Length=370, Percent_Identity=31.0810810810811, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=27.10027100271, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI4557233, Length=305, Percent_Identity=31.8032786885246, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=27.4336283185841, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=26.8617021276596, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI7656849, Length=342, Percent_Identity=27.4853801169591, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI38505218, Length=300, Percent_Identity=29.6666666666667, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI48976061, Length=280, Percent_Identity=29.6428571428571, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI211971008, Length=280, Percent_Identity=29.6428571428571, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI76496475, Length=356, Percent_Identity=27.247191011236, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4557235, Length=356, Percent_Identity=27.247191011236, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI21361497, Length=387, Percent_Identity=25.5813953488372, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI7669494, Length=317, Percent_Identity=29.0220820189274, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4503943, Length=317, Percent_Identity=29.0220820189274, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081958, Length=368, Percent_Identity=26.9021739130435, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786223, Length=365, Percent_Identity=27.3972602739726, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87081702, Length=367, Percent_Identity=25.6130790190736, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=330, Percent_Identity=31.8181818181818, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17569725, Length=327, Percent_Identity=31.4984709480122, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17570075, Length=362, Percent_Identity=30.6629834254144, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17508101, Length=349, Percent_Identity=28.9398280802292, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=28.7878787878788, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17533517, Length=337, Percent_Identity=27.893175074184, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=27.5675675675676, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=352, Percent_Identity=27.2727272727273, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71990804, Length=279, Percent_Identity=30.4659498207885, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=333, Percent_Identity=27.3273273273273, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=344, Percent_Identity=27.3255813953488, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=344, Percent_Identity=27.3255813953488, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=259, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=29.6703296703297, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=353, Percent_Identity=26.9121813031161, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=258, Percent_Identity=27.5193798449612, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660351, Length=359, Percent_Identity=28.9693593314763, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356377, Length=307, Percent_Identity=31.2703583061889, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=28.4182305630027, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21355753, Length=344, Percent_Identity=27.0348837209302, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646207, Length=310, Percent_Identity=28.0645161290323, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281363737, Length=347, Percent_Identity=27.3775216138329, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19920834, Length=315, Percent_Identity=28.2539682539683, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41772; Mature: 41641

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPNPYVESDERKALRQAVASLAASYGHEYYLEKSKTHEPLAELWDEAGKLGFLGVNIP
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHCCCEEEEECCCC
EEYGGGGAGMYELGLVFEELSAAGCPLLLMVVSPAINATIIARYGTDAQKKSWLPAMAEG
HHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCHHHHCCCCHHCCC
SFKMAFAITEPDAGSNSHNIITTAKRDGGDWILNGRKVFISGVNEANAVLVVARTEEAKT
CEEEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCC
GKLKPALFVVPTNTKGFEYTPIDMQLTLPEQQFQVFLDDVRVPGDALVGSEDAALMQLFA
CCCCCEEEEEECCCCCCEECCCEEEEECCHHHHHHHHHHHCCCCCCEECCCHHHHHHHHH
GLNPERIMGAASGVGLTRLALNKATEYVKTRQVWKTPIGAHQAIAHPLAEIKVELELAKL
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
MMQKAATLYDCGDDWGAAEAANMAKYAAADVACRAADRAVQSLGGNGLTTEYGVAPLLNL
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHH
SRFGRIAPVSREMILNFVAQTSLGLPRSY
HHCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQPNPYVESDERKALRQAVASLAASYGHEYYLEKSKTHEPLAELWDEAGKLGFLGVNIP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHCCCEEEEECCCC
EEYGGGGAGMYELGLVFEELSAAGCPLLLMVVSPAINATIIARYGTDAQKKSWLPAMAEG
HHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCHHHHCCCCHHCCC
SFKMAFAITEPDAGSNSHNIITTAKRDGGDWILNGRKVFISGVNEANAVLVVARTEEAKT
CEEEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCC
GKLKPALFVVPTNTKGFEYTPIDMQLTLPEQQFQVFLDDVRVPGDALVGSEDAALMQLFA
CCCCCEEEEEECCCCCCEECCCEEEEECCHHHHHHHHHHHCCCCCCEECCCHHHHHHHHH
GLNPERIMGAASGVGLTRLALNKATEYVKTRQVWKTPIGAHQAIAHPLAEIKVELELAKL
CCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
MMQKAATLYDCGDDWGAAEAANMAKYAAADVACRAADRAVQSLGGNGLTTEYGVAPLLNL
HHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHH
SRFGRIAPVSREMILNFVAQTSLGLPRSY
HHCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]