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The map label for this gene is ctaD [H]

Identifier: 169628137

GI number: 169628137

Start: 1050763

End: 1052325

Strand: Reverse

Name: ctaD [H]

Synonym: MAB_1042c

Alternate gene names: 169628137

Gene position: 1052325-1050763 (Counterclockwise)

Preceding gene: 169628138

Following gene: 169628130

Centisome position: 20.77

GC content: 62.7

Gene sequence:

>1563_bases
ATGTATCTGGTCACATGTTTCGCCTTCTTCATGGTCGGTGGCTTGATGGCGCTGCTCATCCGCGCCGAGCTCACCACGCC
GGGGCTGGCATTCCTCTCCAATGAGCAGTACAACCAGCTGTTCACCATGCACGGCACCGCGATGCTGTTGTTCTACGCCA
CGCCGATCGTGTTCGGCTTCGCCAATGTGGTGCTGCCGCTGCAGATCGGCGCCCCCGACGTCGCCTTCCCACGACTGAAC
GCACTCTCGTTCTGGCTGTTCCTATTTGGTGCGCTCATCGCACTGGCCGGATTCATCACACCCGGCGGTGCCGCCGACTT
CGGCTGGACCGCCTACACGCCGCTCTCCGACGCCATCCACTCTCCGGGTGCGGGCGGCGACTTGTGGATCTTGGGCGTCG
CGGTGGGCGGTCTGGGCACCATTCTGGGCGCGGTAAACATGATCACCACCATCGTGTGCATGCGTGCGCCCGGCATGGTG
ATGTTCCGGATGCCGATCTTCACCTGGAACATCCTGGTGGTCAGCGTGCTGGTGCTGTTGGTGTTCCCGCTGCTGGCAGC
CGCGGCCATCGGACTGGAGGCGGATCGCCGGCTCGGGGCACATCTGTACGACCCCGCCAACGGCGGGGTTCTGCTGTGGC
AGCATCTGTTCTGGTTCTTCGGACACCCGGAGGTCTACGTGCTGGCCCTACCATTCTTCGGAGTCGTGTCGGAGATCTTC
CCGGTGTTCAGCCGCAAGCCGATCTTCGGTTACACCACGCTGGTCTTCGCCACCCTGGGAATCGGAGCGCTGTCGATCGC
GGTGTGGGCGCACCACATGTACGCGACCGGCGCGGTGCTGCTGCCGTTCTTCTCCTTCATGACGTTCCTGATCGCGGTTC
CCACCGGTATCAAGTTCTTCAACTGGATCGGCACCATGTGGAAGGGGCAACTGACCTTCGAGACCCCCATGCTGTTCTCG
ATCGGCTTCCTGGTGACGTTCCTCTTCGGCGGCCTGACCGGTGTCCTTCTCGCCGCTCCCCCAATAGATTTCCACGTCAC
CGATTCGTACTTCGTGGTGGCGCATTTCCACTACACCTTGTTCGGCACCATTGTGTTCGCAAGTTTCGCCGGGGTGTACT
TCTGGTTCCCAAAGATGACGGGCCGCCTGCTCGACGAGCGCCTGGGCAAGTTCCACTTCTGGCTGACCTTCATCGGCTTC
CACGCCACGTTCCTGGTGCAGCACTGGCTGGGTAACGAGGGCATGCCCCGCCGGTACGCCGACTACCTGCCCACCGACGG
CTTCACGGCGCTGAACATCGTGTCCACGGTCGGCGCTTTCATCCTCGGGTCGTCGATGCTGCCGTTCGTCTGGAATGTGT
TCAAGAGCTACCGCTACGGCGAGGTTGTCACGGTCGACGATCCGTGGGGCTACGGCAACTCCCTGGAGTGGGCCACCAGC
TGCCCGCCACCGCGGCACAATTTCACCGAGCTGCCCCGAATCCGTTCGGAACGTCCGGCATTCGAGCTGCACTATCCACA
CATGGTCGAACGCATGCGCGCCGAGGCGCACGTCGGGCACTAG

Upstream 100 bases:

>100_bases
CGAGCTGACGGCAAGTCGTCCTTTTCCCCCGCGCGTAGGGCCTAAAGGCTCTCTTATCTACCGGCTTGTTACCACCACCG
ATCACAAGTTGATCGGCATC

Downstream 100 bases:

>100_bases
CCCGGCACGTGACCGCCGTCCGGTTCACGCCCGAACACGAACCGGCGGCCGGTGATCTGTGCCGGAATGATCCGCACATA
ATGCAGTTTCAGGGTCGGGA

Product: cytochrome c oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MYLVTCFAFFMVGGLMALLIRAELTTPGLAFLSNEQYNQLFTMHGTAMLLFYATPIVFGFANVVLPLQIGAPDVAFPRLN
ALSFWLFLFGALIALAGFITPGGAADFGWTAYTPLSDAIHSPGAGGDLWILGVAVGGLGTILGAVNMITTIVCMRAPGMV
MFRMPIFTWNILVVSVLVLLVFPLLAAAAIGLEADRRLGAHLYDPANGGVLLWQHLFWFFGHPEVYVLALPFFGVVSEIF
PVFSRKPIFGYTTLVFATLGIGALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFS
IGFLVTFLFGGLTGVLLAAPPIDFHVTDSYFVVAHFHYTLFGTIVFASFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGF
HATFLVQHWLGNEGMPRRYADYLPTDGFTALNIVSTVGAFILGSSMLPFVWNVFKSYRYGEVVTVDDPWGYGNSLEWATS
CPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHVGH

Sequences:

>Translated_520_residues
MYLVTCFAFFMVGGLMALLIRAELTTPGLAFLSNEQYNQLFTMHGTAMLLFYATPIVFGFANVVLPLQIGAPDVAFPRLN
ALSFWLFLFGALIALAGFITPGGAADFGWTAYTPLSDAIHSPGAGGDLWILGVAVGGLGTILGAVNMITTIVCMRAPGMV
MFRMPIFTWNILVVSVLVLLVFPLLAAAAIGLEADRRLGAHLYDPANGGVLLWQHLFWFFGHPEVYVLALPFFGVVSEIF
PVFSRKPIFGYTTLVFATLGIGALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFS
IGFLVTFLFGGLTGVLLAAPPIDFHVTDSYFVVAHFHYTLFGTIVFASFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGF
HATFLVQHWLGNEGMPRRYADYLPTDGFTALNIVSTVGAFILGSSMLPFVWNVFKSYRYGEVVTVDDPWGYGNSLEWATS
CPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHVGH
>Mature_520_residues
MYLVTCFAFFMVGGLMALLIRAELTTPGLAFLSNEQYNQLFTMHGTAMLLFYATPIVFGFANVVLPLQIGAPDVAFPRLN
ALSFWLFLFGALIALAGFITPGGAADFGWTAYTPLSDAIHSPGAGGDLWILGVAVGGLGTILGAVNMITTIVCMRAPGMV
MFRMPIFTWNILVVSVLVLLVFPLLAAAAIGLEADRRLGAHLYDPANGGVLLWQHLFWFFGHPEVYVLALPFFGVVSEIF
PVFSRKPIFGYTTLVFATLGIGALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFS
IGFLVTFLFGGLTGVLLAAPPIDFHVTDSYFVVAHFHYTLFGTIVFASFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGF
HATFLVQHWLGNEGMPRRYADYLPTDGFTALNIVSTVGAFILGSSMLPFVWNVFKSYRYGEVVTVDDPWGYGNSLEWATS
CPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHVGH

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=494, Percent_Identity=43.9271255060729, Blast_Score=364, Evalue=1e-100,
Organism=Escherichia coli, GI1786634, Length=528, Percent_Identity=43.5606060606061, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6226519, Length=512, Percent_Identity=38.28125, Blast_Score=336, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6226524, Length=299, Percent_Identity=40.4682274247492, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6226523, Length=227, Percent_Identity=35.2422907488987, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 57719; Mature: 57719

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVTCFAFFMVGGLMALLIRAELTTPGLAFLSNEQYNQLFTMHGTAMLLFYATPIVFGF
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHEEEHHHHHHHHHHHHHHHHHH
ANVVLPLQIGAPDVAFPRLNALSFWLFLFGALIALAGFITPGGAADFGWTAYTPLSDAIH
HHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHC
SPGAGGDLWILGVAVGGLGTILGAVNMITTIVCMRAPGMVMFRMPIFTWNILVVSVLVLL
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHH
VFPLLAAAAIGLEADRRLGAHLYDPANGGVLLWQHLFWFFGHPEVYVLALPFFGVVSEIF
HHHHHHHHHHCCCHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
PVFSRKPIFGYTTLVFATLGIGALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFF
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
NWIGTMWKGQLTFETPMLFSIGFLVTFLFGGLTGVLLAAPPIDFHVTDSYFVVAHFHYTL
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEHHHHHH
FGTIVFASFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGFHATFLVQHWLGNEGMPRRYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
DYLPTDGFTALNIVSTVGAFILGSSMLPFVWNVFKSYRYGEVVTVDDPWGYGNSLEWATS
HCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC
CPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHVGH
CCCCCCCCCCCCCHHCCCCCEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYLVTCFAFFMVGGLMALLIRAELTTPGLAFLSNEQYNQLFTMHGTAMLLFYATPIVFGF
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHEEEHHHHHHHHHHHHHHHHHH
ANVVLPLQIGAPDVAFPRLNALSFWLFLFGALIALAGFITPGGAADFGWTAYTPLSDAIH
HHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHC
SPGAGGDLWILGVAVGGLGTILGAVNMITTIVCMRAPGMVMFRMPIFTWNILVVSVLVLL
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHH
VFPLLAAAAIGLEADRRLGAHLYDPANGGVLLWQHLFWFFGHPEVYVLALPFFGVVSEIF
HHHHHHHHHHCCCHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHH
PVFSRKPIFGYTTLVFATLGIGALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFF
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
NWIGTMWKGQLTFETPMLFSIGFLVTFLFGGLTGVLLAAPPIDFHVTDSYFVVAHFHYTL
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEHHHHHH
FGTIVFASFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGFHATFLVQHWLGNEGMPRRYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
DYLPTDGFTALNIVSTVGAFILGSSMLPFVWNVFKSYRYGEVVTVDDPWGYGNSLEWATS
HCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC
CPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHVGH
CCCCCCCCCCCCCHHCCCCCEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]