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The map label for this gene is yfjR [H]

Identifier: 169628138

GI number: 169628138

Start: 1052515

End: 1053387

Strand: Reverse

Name: yfjR [H]

Synonym: MAB_1043c

Alternate gene names: 169628138

Gene position: 1053387-1052515 (Counterclockwise)

Preceding gene: 169628139

Following gene: 169628137

Centisome position: 20.79

GC content: 64.6

Gene sequence:

>873_bases
ATGAGCACAATTGCCGTCATCGGACTGGGAGCCATGGGAAAGGCCATGGCAGACAATCTCGTTCAGGCAGGACATCAGGT
ATCCGTGTGGAACCGCTCACCCGCTCCCGTCGCAGAGCTCGCAGCGGTCGGCGCCCGCCCATTGGATTCCGTGGCACAGG
CCTTCGACTCCGGTGTGGTTTTCTCGGTACTGGCCGATGACCACGCGGTGACGGAGACGTTGTTGACCCCAGAGGTCCTC
GCGGCCGGGCATGGTGCGCTGCACGTGAACCTGGCCACCGTCAGCGCCCGGCTGGCCGATCGGGCGACGGCATTGCACGA
CGAGCACGGCGTGGGATACGTCGCGGCACCGGTGTTCGGCCGCGTCCCCGTCGCGCAAGCCGGACAGTTACAGGTATTGG
CGGCGGGTGCGGCCGCACAGATCGACAAGGCTCAATCGTTCTTCGACGTCATCGGGGCGCGTACGTGGCGATTGGGCGAT
GCCCCACGGCAAGCCAATGTCGTCAAGATCATCGGAAATTTCCTCATCGCATCGGCCATCCAGTCGTTGAGTGAGGCCGT
CAGCATGGCGGAACGCTCCGGAGTGGACTCCGCACTGCTGGTGGAACTGTTGACCAGCACCCTGTTTCAGGGACCCGCCT
ACAGCAGCTACGGCAAGCTCATCGCCACCTCGGCCTACGAACCAGCCGGATTCACAACCACCCTGGGCCGCAAGGATGTC
GGTCTGGCATTAGAGGTGGCCGCGGATACCGGGCTGCGGCTCCCGTTCGGCGAGATCCTGCGAACGGTTTTCGATGAGGC
ACTCGCGGGCGGACACGCCAACCTGGACTGGTCCTCCATCGCCGACCTACAGCGGGCGCGCGACGCAGAGTGA

Upstream 100 bases:

>100_bases
TGTCCTATCTGACCGACCCGTGGGGCACGGTCATCGAATTGATGAGCCACGACTACACCGACATCTTTACCCATTGGCCC
ACCGAAACAGGAGCACACTC

Downstream 100 bases:

>100_bases
CTATGGCATGATGTCCGCAGGAATGCCTCACGTACACAGGCGAATCGCACTGTTTTCGTATGGAGGTTTCCTGTGGCTAC
ATCATCTGTCGAGCTGACGG

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSTIAVIGLGAMGKAMADNLVQAGHQVSVWNRSPAPVAELAAVGARPLDSVAQAFDSGVVFSVLADDHAVTETLLTPEVL
AAGHGALHVNLATVSARLADRATALHDEHGVGYVAAPVFGRVPVAQAGQLQVLAAGAAAQIDKAQSFFDVIGARTWRLGD
APRQANVVKIIGNFLIASAIQSLSEAVSMAERSGVDSALLVELLTSTLFQGPAYSSYGKLIATSAYEPAGFTTTLGRKDV
GLALEVAADTGLRLPFGEILRTVFDEALAGGHANLDWSSIADLQRARDAE

Sequences:

>Translated_290_residues
MSTIAVIGLGAMGKAMADNLVQAGHQVSVWNRSPAPVAELAAVGARPLDSVAQAFDSGVVFSVLADDHAVTETLLTPEVL
AAGHGALHVNLATVSARLADRATALHDEHGVGYVAAPVFGRVPVAQAGQLQVLAAGAAAQIDKAQSFFDVIGARTWRLGD
APRQANVVKIIGNFLIASAIQSLSEAVSMAERSGVDSALLVELLTSTLFQGPAYSSYGKLIATSAYEPAGFTTTLGRKDV
GLALEVAADTGLRLPFGEILRTVFDEALAGGHANLDWSSIADLQRARDAE
>Mature_289_residues
STIAVIGLGAMGKAMADNLVQAGHQVSVWNRSPAPVAELAAVGARPLDSVAQAFDSGVVFSVLADDHAVTETLLTPEVLA
AGHGALHVNLATVSARLADRATALHDEHGVGYVAAPVFGRVPVAQAGQLQVLAAGAAAQIDKAQSFFDVIGARTWRLGDA
PRQANVVKIIGNFLIASAIQSLSEAVSMAERSGVDSALLVELLTSTLFQGPAYSSYGKLIATSAYEPAGFTTTLGRKDVG
LALEVAADTGLRLPFGEILRTVFDEALAGGHANLDWSSIADLQRARDAE

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI23308751, Length=307, Percent_Identity=24.1042345276873, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI40556376, Length=285, Percent_Identity=24.2105263157895, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1790315, Length=290, Percent_Identity=30.3448275862069, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786719, Length=281, Percent_Identity=28.1138790035587, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693186, Length=289, Percent_Identity=25.9515570934256, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655230, Length=290, Percent_Identity=26.2068965517241, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922568, Length=290, Percent_Identity=26.2068965517241, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28574115, Length=291, Percent_Identity=25.7731958762887, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 29962; Mature: 29831

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00895 3_HYDROXYISOBUT_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIAVIGLGAMGKAMADNLVQAGHQVSVWNRSPAPVAELAAVGARPLDSVAQAFDSGVV
CCCEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCHHHHHHHHCCCCE
FSVLADDHAVTETLLTPEVLAAGHGALHVNLATVSARLADRATALHDEHGVGYVAAPVFG
EEEECCCHHHHHHHHCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCHHC
RVPVAQAGQLQVLAAGAAAQIDKAQSFFDVIGARTWRLGDAPRQANVVKIIGNFLIASAI
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHH
QSLSEAVSMAERSGVDSALLVELLTSTLFQGPAYSSYGKLIATSAYEPAGFTTTLGRKDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEEECCCCCC
GLALEVAADTGLRLPFGEILRTVFDEALAGGHANLDWSSIADLQRARDAE
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
STIAVIGLGAMGKAMADNLVQAGHQVSVWNRSPAPVAELAAVGARPLDSVAQAFDSGVV
CCEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCHHHHHHHHCCCCE
FSVLADDHAVTETLLTPEVLAAGHGALHVNLATVSARLADRATALHDEHGVGYVAAPVFG
EEEECCCHHHHHHHHCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCHHC
RVPVAQAGQLQVLAAGAAAQIDKAQSFFDVIGARTWRLGDAPRQANVVKIIGNFLIASAI
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHH
QSLSEAVSMAERSGVDSALLVELLTSTLFQGPAYSSYGKLIATSAYEPAGFTTTLGRKDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEEECCCCCC
GLALEVAADTGLRLPFGEILRTVFDEALAGGHANLDWSSIADLQRARDAE
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]