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The map label for this gene is dinB2 [H]

Identifier: 169628074

GI number: 169628074

Start: 984552

End: 985757

Strand: Reverse

Name: dinB2 [H]

Synonym: MAB_0977c

Alternate gene names: 169628074

Gene position: 985757-984552 (Counterclockwise)

Preceding gene: 169628078

Following gene: 169628072

Centisome position: 19.45

GC content: 66.17

Gene sequence:

>1206_bases
ATGACCGGGACAGCCAGCATCCTGCATGCCGATCTGGACTCGTTCTACGCCTCCGTCGAGCAACGTGATGCGCCGGCACT
GCGCGACCGCCCGGTGATCGTCGGGGGCGGTGTCGTGCTCGCCGCCAGCTACGAAGCAAAACATTGTGGCGTGCGTACCG
CCATGGGAGGTCGTCAGGCGCTACGGCTCTGCCCGCACGCGGTGGTGGTACCACCGCGTTTCGACGCCTACAGCGCCGCG
AGCAAGTTGGTGTTCGAGGTCTTCCGGGATACCACTCCCCTGGTCGAGCCGCTGTCCATCGACGAGGCGTTTCTGGATGT
GTCCGGTCTGCAGCGGATCTCAGGGGCGCCAAGCGATATCGCGGCCGCATTGCGCTTGGAGGTGCGGCGCCGGGCGGGAC
TACCGATCACCGTCGGCATCGCCCGCACCAAGTTCTTGGCCAAAGTCGCCAGCCGCCAGGGCAAGCCCGACGGACTGTTG
GTGGTGGAGCCGCACGAGGAGTTGTCGTTTCTGCGCCCGCTGCCGGTGCAGGCGCTGTGGGGAGTCGGATCGGTCACCGC
CGAGAAACTGCGGGTGTATGGCATCCGTACCGTCGCGGACGTGGCCGATCTGGGCGAGTCCACCCTGGCGTCGATGGTCG
GACGCGCCATGGGGCATCAATTGCATTGTCTGGCAAACAATATCGATCCACGACGGGTGGATGGTGGACGGCGGCGGCGC
TCGATCGGTGCGCAGTGCGCGCTTGGCCGCGGGCCACGAGCGGACAGCGAGATCGATGCCATCGCAACACAACTCATGGA
GCGGATTGCCCGCCGCATGCGCGGCACCGGCCGCAGCTGTCGCACGGTGGTGCTACGACTGCGTTTCGGCGACTACACCC
GCGCCACGCGCTCACGCACCGTGCCGCGACCCACCACGTCCACCGAACGCCTCCTGTCAGTGGCCCGCGAGCTTGTCAAA
GACGCCGGCCCGCTCATCAAAGAACGGGGCATCACTCTGATCGGATTCTCCGTATCCAACTTCGACCCTTGTGGCGCAGC
ACAGTTGGAGCTGCCCTTCTCGGATGCGGCGGAAAACACCTTGGCGCTCGACAGCACCCTTGATGGGCTGCGCGACAGGT
TCGGAACCCGGTCGGTCACCCGCGCCAACCTGTTGCACGGAGGCGGGCGGGAGGAATGGGGCATCCCGACCTTCGAAGAC
CTCTAG

Upstream 100 bases:

>100_bases
CCGGGCGCCATCAAGGATTGCCCAGTGATTCTCCGAATCAACCGCCGGTTGGGCAAATCAACCCGATCCGGCTGTCGGAC
CCCGGTGCGAGCATCGGATC

Downstream 100 bases:

>100_bases
CGAGACCGGGACGCCCGGGCCATGATCAGGAGTCCACGGAGCACAGCCAGAAGGTGCCGCCAGTGGTGTCCCTTATCAGC
GCCATCCGGCCATACGGCGT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTGTASILHADLDSFYASVEQRDAPALRDRPVIVGGGVVLAASYEAKHCGVRTAMGGRQALRLCPHAVVVPPRFDAYSAA
SKLVFEVFRDTTPLVEPLSIDEAFLDVSGLQRISGAPSDIAAALRLEVRRRAGLPITVGIARTKFLAKVASRQGKPDGLL
VVEPHEELSFLRPLPVQALWGVGSVTAEKLRVYGIRTVADVADLGESTLASMVGRAMGHQLHCLANNIDPRRVDGGRRRR
SIGAQCALGRGPRADSEIDAIATQLMERIARRMRGTGRSCRTVVLRLRFGDYTRATRSRTVPRPTTSTERLLSVARELVK
DAGPLIKERGITLIGFSVSNFDPCGAAQLELPFSDAAENTLALDSTLDGLRDRFGTRSVTRANLLHGGGREEWGIPTFED
L

Sequences:

>Translated_401_residues
MTGTASILHADLDSFYASVEQRDAPALRDRPVIVGGGVVLAASYEAKHCGVRTAMGGRQALRLCPHAVVVPPRFDAYSAA
SKLVFEVFRDTTPLVEPLSIDEAFLDVSGLQRISGAPSDIAAALRLEVRRRAGLPITVGIARTKFLAKVASRQGKPDGLL
VVEPHEELSFLRPLPVQALWGVGSVTAEKLRVYGIRTVADVADLGESTLASMVGRAMGHQLHCLANNIDPRRVDGGRRRR
SIGAQCALGRGPRADSEIDAIATQLMERIARRMRGTGRSCRTVVLRLRFGDYTRATRSRTVPRPTTSTERLLSVARELVK
DAGPLIKERGITLIGFSVSNFDPCGAAQLELPFSDAAENTLALDSTLDGLRDRFGTRSVTRANLLHGGGREEWGIPTFED
L
>Mature_400_residues
TGTASILHADLDSFYASVEQRDAPALRDRPVIVGGGVVLAASYEAKHCGVRTAMGGRQALRLCPHAVVVPPRFDAYSAAS
KLVFEVFRDTTPLVEPLSIDEAFLDVSGLQRISGAPSDIAAALRLEVRRRAGLPITVGIARTKFLAKVASRQGKPDGLLV
VEPHEELSFLRPLPVQALWGVGSVTAEKLRVYGIRTVADVADLGESTLASMVGRAMGHQLHCLANNIDPRRVDGGRRRRS
IGAQCALGRGPRADSEIDAIATQLMERIARRMRGTGRSCRTVVLRLRFGDYTRATRSRTVPRPTTSTERLLSVARELVKD
AGPLIKERGITLIGFSVSNFDPCGAAQLELPFSDAAENTLALDSTLDGLRDRFGTRSVTRANLLHGGGREEWGIPTFEDL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=250, Percent_Identity=30.4, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI7706681, Length=250, Percent_Identity=30.4, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI7705344, Length=118, Percent_Identity=44.9152542372881, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI154350220, Length=347, Percent_Identity=25.6484149855908, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1786425, Length=355, Percent_Identity=36.6197183098592, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787432, Length=206, Percent_Identity=33.495145631068, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=360, Percent_Identity=25.2777777777778, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI193205700, Length=99, Percent_Identity=38.3838383838384, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=335, Percent_Identity=24.1791044776119, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21355641, Length=398, Percent_Identity=23.6180904522613, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644984, Length=398, Percent_Identity=23.6180904522613, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43364; Mature: 43233

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTASILHADLDSFYASVEQRDAPALRDRPVIVGGGVVLAASYEAKHCGVRTAMGGRQA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEECCCHHHCCCHHHCCHHHH
LRLCPHAVVVPPRFDAYSAASKLVFEVFRDTTPLVEPLSIDEAFLDVSGLQRISGAPSDI
HHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
AAALRLEVRRRAGLPITVGIARTKFLAKVASRQGKPDGLLVVEPHEELSFLRPLPVQALW
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCHHHHH
GVGSVTAEKLRVYGIRTVADVADLGESTLASMVGRAMGHQLHCLANNIDPRRVDGGRRRR
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEHHCCCCCHHCCCCHHHH
SIGAQCALGRGPRADSEIDAIATQLMERIARRMRGTGRSCRTVVLRLRFGDYTRATRSRT
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHCCC
VPRPTTSTERLLSVARELVKDAGPLIKERGITLIGFSVSNFDPCGAAQLELPFSDAAENT
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCCC
LALDSTLDGLRDRFGTRSVTRANLLHGGGREEWGIPTFEDL
EEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGTASILHADLDSFYASVEQRDAPALRDRPVIVGGGVVLAASYEAKHCGVRTAMGGRQA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEECCCHHHCCCHHHCCHHHH
LRLCPHAVVVPPRFDAYSAASKLVFEVFRDTTPLVEPLSIDEAFLDVSGLQRISGAPSDI
HHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
AAALRLEVRRRAGLPITVGIARTKFLAKVASRQGKPDGLLVVEPHEELSFLRPLPVQALW
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCHHHHH
GVGSVTAEKLRVYGIRTVADVADLGESTLASMVGRAMGHQLHCLANNIDPRRVDGGRRRR
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEHHCCCCCHHCCCCHHHH
SIGAQCALGRGPRADSEIDAIATQLMERIARRMRGTGRSCRTVVLRLRFGDYTRATRSRT
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHCCC
VPRPTTSTERLLSVARELVKDAGPLIKERGITLIGFSVSNFDPCGAAQLELPFSDAAENT
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCCC
LALDSTLDGLRDRFGTRSVTRANLLHGGGREEWGIPTFEDL
EEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]