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The map label for this gene is paaK [H]

Identifier: 169628010

GI number: 169628010

Start: 902919

End: 904244

Strand: Direct

Name: paaK [H]

Synonym: MAB_0911

Alternate gene names: 169628010

Gene position: 902919-904244 (Clockwise)

Preceding gene: 169628009

Following gene: 169628011

Centisome position: 17.82

GC content: 60.71

Gene sequence:

>1326_bases
ATGATCGAAACCGTCGAACGCAGCGAGAGCCACAGCGTGGCGTGCTCGCCTGATGAGCTCGAGCCCATCGAAATGGCCTC
GCGTGACGAAATTTCCGCACTGCAATTGGAGCGGATGAAGTGGTCGCTGCGCCACGCCTACGACAATGTCGCTCATTATC
GACATGCGTTCGATCAAGCGGGGGTGCACCCCAACGACCTCAAGGACCTCGCCGACCTGGCACACTTTCCGTTCACCACC
AAGGCCGACCTCAGGCAGACCTACCCCTTCGGGATGTTCGCCGTCCCGCAATCCCAGATCTCACGGGTCCACGCCTCATC
GGGCACCACCGGCCAACCCACCGTAGTGGGGTATACCGCCGCCGACATCGACATCTGGGCGAACCTCGTCGCCCGCTGCC
TTCGTGCCGCCGGCGTCCGGTCAACCGACAAAGTGCACGTCTCCTATGGCTATGGGCTGTTCACCGGGGGTCTGGGCGCA
CACTACGGCGCAGAACGACTGGGCTGCACAGTAATTCCGGTCTCGGGCGGTATGACCGAACGTCAGCTGCAACTCATCAC
AGACTTTCAGCCCGACGCCATCATGATCACCCCCTCCTACATGCTCACGTTGCTCGACGCGATGGACCGCGTCGGCATCG
ACCCGCGCAGCACCTCGTTGCGCACAGGAATTTTCGGGGCGGAACCATGGACCGAGCAGATGCGAAGCGAACTCGAACAC
AAGCTCGGCATCAGTGCTGTCGACATCTACGGCCTATCCGAGTTGCTTGGTCCTGGAGTGGCCCAGGAATGCGTTGAAAC
CAAAGACGGACTGCATATTTGGGAAGATCACTTCTACCCCGAGATCATCGATCCGGACACCGGCCAGGTGTTGCCCGACG
GCTCCGAAGGCGAGCTCGTGTTCACGTCGCTGACCAAGCAGGCCCTGCCGATCATTCGCTACCGCACTCGCGATCTCACC
AAGCTGCTTCCCGGGACTGCCCGCAGCATGCGCCGTATGCGCAAAGTAACCAGCCGTAGTGACGACATGATCATTCTGCG
CGGGGTCAACCTGTTCCCGTCCCAAATCGAAGAGCTTATTCTCACCATTCCTACGCTCGCACCACATTTCGAGTGTGTGA
TTGACCGACCGACGCGCTTGGACCGGCTGACTGTGAACGTGGAACACCGTTCGGGGACAACGCCTGCCGAATGCGACACC
GCAGGGGCAGCGCTGGCGCACCTGATTAAGCAGAAGATCGGCGTCAGTGTCACAGTCGACGTGCTGGCGCCCAATACGAT
TGCCCGGTCCGAGGGCAAAGCCCGAAGGATCGTCGACCATAGATAG

Upstream 100 bases:

>100_bases
GACGCCGGATTTGTGCTGACCTGTCAGTCCTATCCGACCACCGATTCATTGACCGTCGACTTCGACGCCTGAAATCCCAC
CTCACCCACCGGAGTACGCC

Downstream 100 bases:

>100_bases
CGCCGGTCACGGACGGTTTTGGCACACTATGTCGATGGATCGACCAGATGCGCATGAGCTGTGCGCGGCAGTAGCCCAGC
GAATCGAGCGCAACGAGCCA

Product: putative phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MIETVERSESHSVACSPDELEPIEMASRDEISALQLERMKWSLRHAYDNVAHYRHAFDQAGVHPNDLKDLADLAHFPFTT
KADLRQTYPFGMFAVPQSQISRVHASSGTTGQPTVVGYTAADIDIWANLVARCLRAAGVRSTDKVHVSYGYGLFTGGLGA
HYGAERLGCTVIPVSGGMTERQLQLITDFQPDAIMITPSYMLTLLDAMDRVGIDPRSTSLRTGIFGAEPWTEQMRSELEH
KLGISAVDIYGLSELLGPGVAQECVETKDGLHIWEDHFYPEIIDPDTGQVLPDGSEGELVFTSLTKQALPIIRYRTRDLT
KLLPGTARSMRRMRKVTSRSDDMIILRGVNLFPSQIEELILTIPTLAPHFECVIDRPTRLDRLTVNVEHRSGTTPAECDT
AGAALAHLIKQKIGVSVTVDVLAPNTIARSEGKARRIVDHR

Sequences:

>Translated_441_residues
MIETVERSESHSVACSPDELEPIEMASRDEISALQLERMKWSLRHAYDNVAHYRHAFDQAGVHPNDLKDLADLAHFPFTT
KADLRQTYPFGMFAVPQSQISRVHASSGTTGQPTVVGYTAADIDIWANLVARCLRAAGVRSTDKVHVSYGYGLFTGGLGA
HYGAERLGCTVIPVSGGMTERQLQLITDFQPDAIMITPSYMLTLLDAMDRVGIDPRSTSLRTGIFGAEPWTEQMRSELEH
KLGISAVDIYGLSELLGPGVAQECVETKDGLHIWEDHFYPEIIDPDTGQVLPDGSEGELVFTSLTKQALPIIRYRTRDLT
KLLPGTARSMRRMRKVTSRSDDMIILRGVNLFPSQIEELILTIPTLAPHFECVIDRPTRLDRLTVNVEHRSGTTPAECDT
AGAALAHLIKQKIGVSVTVDVLAPNTIARSEGKARRIVDHR
>Mature_441_residues
MIETVERSESHSVACSPDELEPIEMASRDEISALQLERMKWSLRHAYDNVAHYRHAFDQAGVHPNDLKDLADLAHFPFTT
KADLRQTYPFGMFAVPQSQISRVHASSGTTGQPTVVGYTAADIDIWANLVARCLRAAGVRSTDKVHVSYGYGLFTGGLGA
HYGAERLGCTVIPVSGGMTERQLQLITDFQPDAIMITPSYMLTLLDAMDRVGIDPRSTSLRTGIFGAEPWTEQMRSELEH
KLGISAVDIYGLSELLGPGVAQECVETKDGLHIWEDHFYPEIIDPDTGQVLPDGSEGELVFTSLTKQALPIIRYRTRDLT
KLLPGTARSMRRMRKVTSRSDDMIILRGVNLFPSQIEELILTIPTLAPHFECVIDRPTRLDRLTVNVEHRSGTTPAECDT
AGAALAHLIKQKIGVSVTVDVLAPNTIARSEGKARRIVDHR

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=428, Percent_Identity=60.981308411215, Blast_Score=545, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48737; Mature: 48737

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETVERSESHSVACSPDELEPIEMASRDEISALQLERMKWSLRHAYDNVAHYRHAFDQA
CCCCCCCCCCCCEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVHPNDLKDLADLAHFPFTTKADLRQTYPFGMFAVPQSQISRVHASSGTTGQPTVVGYTA
CCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEH
ADIDIWANLVARCLRAAGVRSTDKVHVSYGYGLFTGGLGAHYGAERLGCTVIPVSGGMTE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCCCHHCCHHHHCEEEEECCCCCCH
RQLQLITDFQPDAIMITPSYMLTLLDAMDRVGIDPRSTSLRTGIFGAEPWTEQMRSELEH
HHHHHEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KLGISAVDIYGLSELLGPGVAQECVETKDGLHIWEDHFYPEIIDPDTGQVLPDGSEGELV
HHCCCEEECCCHHHHHCCCHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCEE
FTSLTKQALPIIRYRTRDLTKLLPGTARSMRRMRKVTSRSDDMIILRGVNLFPSQIEELI
EEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
LTIPTLAPHFECVIDRPTRLDRLTVNVEHRSGTTPAECDTAGAALAHLIKQKIGVSVTVD
HHHCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
VLAPNTIARSEGKARRIVDHR
EECCCHHHCCCCCHHHCCCCC
>Mature Secondary Structure
MIETVERSESHSVACSPDELEPIEMASRDEISALQLERMKWSLRHAYDNVAHYRHAFDQA
CCCCCCCCCCCCEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVHPNDLKDLADLAHFPFTTKADLRQTYPFGMFAVPQSQISRVHASSGTTGQPTVVGYTA
CCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEH
ADIDIWANLVARCLRAAGVRSTDKVHVSYGYGLFTGGLGAHYGAERLGCTVIPVSGGMTE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCCCHHCCHHHHCEEEEECCCCCCH
RQLQLITDFQPDAIMITPSYMLTLLDAMDRVGIDPRSTSLRTGIFGAEPWTEQMRSELEH
HHHHHEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KLGISAVDIYGLSELLGPGVAQECVETKDGLHIWEDHFYPEIIDPDTGQVLPDGSEGELV
HHCCCEEECCCHHHHHCCCHHHHHHHCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCEE
FTSLTKQALPIIRYRTRDLTKLLPGTARSMRRMRKVTSRSDDMIILRGVNLFPSQIEELI
EEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
LTIPTLAPHFECVIDRPTRLDRLTVNVEHRSGTTPAECDTAGAALAHLIKQKIGVSVTVD
HHHCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
VLAPNTIARSEGKARRIVDHR
EECCCHHHCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]